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List of works by Manuel Mattheisen

1,25-Dihydroxyvitamin D modulates L-type voltage-gated calcium channels in a subset of neurons in the developing mouse prefrontal cortex

scientific article published on 11 November 2019

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder

scientific article published on 2 December 2017

A German genome-wide linkage scan for type 2 diabetes supports the existence of a metabolic syndrome locus on chromosome 1p36.13 and a type 2 diabetes locus on chromosome 16p12.2.

scientific article published on 27 April 2007

A Novel Locus for Ectodermal Dysplasia of Hair, Nail and Skin Pigmentation Anomalies Maps to Chromosome 18p11.32-p11.31.

scientific article published on 26 June 2015

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder

scientific article

A genetic investigation of sex bias in the prevalence of attention deficit hyperactivity disorder

article

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry

scientific article published on 3 December 2015

A major role for common genetic variation in anxiety disorders

scientific article published on 20 November 2019

A mega-analysis of genome-wide association studies for major depressive disorder

scientific article

A novel locus for arterial hypertension on chromosome 1p36 maps to a metabolic syndrome trait cluster in the Sorbs, a Slavic population isolate in Germany

scientific article published in May 2009

A polygenic resilience score moderates the genetic risk for schizophrenia

scientific article published on 06 September 2019

A reappraisal of the association between Dysbindin (DTNBP1) and schizophrenia in a large combined case-control and family-based sample of German ancestry

scientific article

A reappraisal of the association between Dysbindin (DTNBP1) and schizophrenia in a large combined case-control and family-based sample of German ancestry

article

Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility.

scientific article published on 09 April 2013

Altered Functional Subnetwork During Emotional Face Processing: A Potential Intermediate Phenotype for Schizophrenia

scientific article published on 4 May 2016

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder

scientific article published on 23 July 2014

Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.

scientific article published on 31 May 2018

Association between copy number variants in 16p11.2 and major depressive disorder in a German case-control sample

scientific article

Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe

scientific article

Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder

scientific article published on 11 April 2012

Association of COMT genotypes with S-COMT promoter methylation in growth-discordant monozygotic twins and healthy adults ⬇️

scientific article published on September 1, 2011

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

scholarly article by Miruna C. Barbu et al published July 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

scientific article

Association of the polygenic risk score for schizophrenia with mortality and suicidal behavior - A Danish population-based study.

scientific article published on 06 December 2016

Beyond GWAS in COPD: probing the landscape between gene-set associations, genome-wide associations and protein-protein interaction networks

scientific article

Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1.

scientific article

Brain-specific tryptophan hydroxylase 2 (TPH2): a functional Pro206Ser substitution and variation in the 5'-region are associated with bipolar affective disorder

scientific article

Candidate gene association study implicates p63 in the etiology of nonsyndromic bladder-exstrophy-epispadias complex

scientific article

Common and rare variant analysis in early-onset bipolar disorder vulnerability

scientific article published on 11 August 2014

Common genetic variants influence human subcortical brain structures

scientific article

Common risk variants identified in autism spectrum disorder

Common variant at 16p11.2 conferring risk of psychosis.

scientific article

Common variants at VRK2 and TCF4 conferring risk of schizophrenia

scientific article published on 26 July 2011

Common variants conferring risk of schizophrenia

scientific article

Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia.

scientific article

Convergent lines of evidence support CAMKK2 as a schizophrenia susceptibility gene

scientific article

Copy number variants in German patients with schizophrenia

scientific article

DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder

scientific article

DNA Methylation at the Neonatal State and at the Time of Diagnosis: Preliminary Support for an Association with the Estrogen Receptor 1, Gamma-Aminobutyric Acid B Receptor 1, and Myelin Oligodendrocyte Glycoprotein in Female Adolescent Patients with

scientific article published on 18 March 2016

Detecting significant genotype-phenotype association rules in bipolar disorder: market research meets complex genetics

article

Diagnosed Anxiety Disorders and the Risk of Subsequent Anorexia Nervosa: A Danish Population Register Study

scientific article published on 8 September 2015

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

scholarly article published 3 June 2017

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

scientific article published on 26 November 2018

Dissection of phenotype reveals possible association between schizophrenia and Glutamate Receptor Delta 1 (GRID1) gene promoter

scientific article

Duplications in RB1CC1 are associated with schizophrenia; identification in large European sample sets.

scientific article

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

scientific article published on 21 April 2016

Efficient strategy for detecting gene × gene joint action and its application in schizophrenia

scientific article

Evidence for linkage of the bladder exstrophy-epispadias complex on chromosome 4q31.21-22 and 19q13.31-41 from a consanguineous Iranian family

scientific article published in September 2010

Examination of the shared genetic basis of anorexia nervosa and obsessive-compulsive disorder.

scientific article

Expanding the range of ZNF804A variants conferring risk of psychosis

scientific article published on 5 January 2010

Explorative two-locus linkage analysis suggests a multiplicative interaction between the 7q32 and 16p13 myoclonic seizures-related photosensitivity loci

article

FZD6 encoding the Wnt receptor frizzled 6 is mutated in autosomal-recessive nail dysplasia.

scientific article published on 4 April 2012

Functional and genetic characterization of the non-lysosomal glucosylceramidase 2 as a modifier for Gaucher disease

scientific article published on 26 September 2013

Functional impact of a recently identified quantitative trait locus for hippocampal volume with genome-wide support

scientific article published on 23 July 2013

Further evidence for the impact of a genome-wide-supported psychosis risk variant in ZNF804A on the Theory of Mind Network

scientific article

GWAS-based pathway analysis differentiates between fluid and crystallized intelligence.

scientific article

Gender-specific association of variants in the AKR1C1 gene with dimensional anxiety in patients with panic disorder: additional evidence for the importance of neurosteroids in anxiety?

scientific article published on 3 January 2014

Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder

scientific article

Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders

scientific article

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic Markers of ADHD-Related Variations in Intracranial Volume

scientific article published on 01 March 2019

Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study

scientific article published on 22 May 2019

Genetic architecture of subcortical brain structures in 38,851 individuals

scientific article published on 21 October 2019

Genetic dissection of photosensitivity and its relation to idiopathic generalized epilepsy

scientific article

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept

scientific article published on February 2016

Genetic markers of ADHD-related variations in intracranial volume

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

scientific article published on 21 January 2016

Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia

scientific article published on 24 September 2012

Genetic variation in the lymphotoxin-α (LTA)/tumour necrosis factor-α (TNFα) locus as a risk factor for idiopathic achalasia

scientific article published on 20 November 2013

Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder

scientific article

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

scientific article published on 26 April 2018

Genome-wide association data provide further support for an association between 5-HTTLPR and major depressive disorder

scientific article

Genome-wide association study and meta-analysis identify ISL1 as genome-wide significant susceptibility gene for bladder exstrophy

scientific article

Genome-wide association study and mouse expression data identify a highly conserved 32 kb intergenic region between WNT3 and WNT9b as possible susceptibility locus for isolated classic exstrophy of the bladder.

scientific article

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

scientific article

Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder

scientific article

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate

scientific article

Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS

scientific article

Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

article

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression

scientific article published on 11 November 2019

Genome-wide association study reveals two new risk loci for bipolar disorder

scientific article (publication date: 11 March 2014)

Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression

scientific article

Genome-wide linkage scan of nonsyndromic orofacial clefting in 91 families of central European origin

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci

scientific journal article

Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1.

scientific article published on 25 September 2012

Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster

scientific article published on 18 October 2011

Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci

scientific article

Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder

scientific article published in March 2011

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

scientific article published on 8 August 2017

Genotype-phenotype association mining in bipolar disorder: market research meets complex genetics

article

High factor VIII levels in venous thromboembolism show linkage to imprinted loci on chromosomes 5 and 11

scientific article published on 07 September 2004

High loading of polygenic risk in cases with chronic schizophrenia

scientific article published on September 2015

Hippocampal function in healthy carriers of the CLU Alzheimer's disease risk variant

scientific article published in December 2011

Hypomethylation and increased expression of the putative oncogene ELMO3 are associated with lung cancer development and metastases formation.

scientific article published on 23 May 2014

Identification of common genetic risk variants for autism spectrum disorder

scientific article published on 25 February 2019

Identification of common variants associated with human hippocampal and intracranial volumes

scientific article published on 15 April 2012

Identification of shared risk loci and pathways for bipolar disorder and schizophrenia

scientific article

Identification of the BRD1 interaction network and its impact on mental disorder risk

scientific journal article

Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance

scientific article published on 3 September 2015

Increased mortality among people with anxiety disorders: total population study

scientific article published on 7 July 2016

Independent evidence for the selective influence of GABA(A) receptors on one component of the bipolar disorder phenotype

scientific article published on 15 June 2010

Inferential testing for linkage with GENEHUNTER-MODSCORE: The impact of the pedigree structure on the null distribution of multipoint MOD scores

Influence of Polygenic Risk Scores on the Association Between Infections and Schizophrenia

scientific article published on 19 April 2016

Integrated Genome-Wide Pathway Association Analysis with INTERSNP

article

Integrated pathway-based approach identifies association between genomic regions at CTCF and CACNB2 and schizophrenia

scientific article

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia

scientific article

Investigation of manic and euthymic episodes identifies state- and trait-specific gene expression and STAB1 as a new candidate gene for bipolar disorder

scientific article

Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia

scientific article

Linkage analysis using sex-specific recombination fractions with GENEHUNTER-MODSCORE

article

Linkage-disequilibrium-based binning affects the interpretation of GWASs

scientific article published on 22 March 2012

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

scientific article published on 8 April 2022

Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility

scientific article

Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.

scientific article

MicroRNA hsa-miR-4717-5p regulates RGS2 and may be a risk factor for anxiety-related traits

scientific article published on 2 April 2015

Neuregulin 3 is associated with attention deficits in schizophrenia and bipolar disorder

scientific article published on 25 July 2012

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

scientific article

Nine new twin pairs with esophageal atresia: a review of the literature and performance of a twin study of the disorder

scientific article published on 30 January 2012

No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study

scientific article

No evidence for an involvement of copy number variation in ABCA13 in schizophrenia, bipolar disorder, or major depressive disorder

scientific article published in February 2013

Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data

scientific article

Novel genetic loci associated with hippocampal volume

scientific article published on 18 January 2017

Novel genetic loci underlying human intracranial volume identified through genome-wide association

scientific article (publication date: 3 October 2016)

Obsessive-Compulsive Disorder and Autism Spectrum Disorders: Longitudinal and Offspring Risk

scientific article published on 11 November 2015

Obsessive-compulsive disorder as a risk factor for schizophrenia: a nationwide study

scientific article

On association analysis of rare variants under population substructure: an approach for the detection of subjects that can cause bias in the analysis--T opt: an outlier detection method

scientific article published on 14 May 2013

Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis.

scientific article published on July 2015

Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder

scientific article published on 01 February 2019

Quick, "imputation-free" meta-analysis with proxy-SNPs

scientific article

RETRACTED: Identification of gene ontologies linked to prefrontal-hippocampal functional coupling in the human brain

retracted scientific article

Rare autosomal copy number variations in early-onset familial Alzheimer's disease

scientific article published on 11 June 2013

Replication of brain function effects of a genome-wide supported psychiatric risk variant in the CACNA1C gene and new multi-locus effects

scientific article

Replication of functional serotonin receptor type 3A and B variants in bipolar affective disorder: a European multicenter study

scientific article published on 17 April 2012

Resequencing and follow-up of neurexin 1 (NRXN1) in schizophrenia patients

Retraction for Dixson et al., Identification of gene ontologies linked to prefrontal-hippocampal functional coupling in the human brain

scientific article published on 2 September 2014

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis

scientific article

Role of common and rare APP DNA sequence variants in Alzheimer disease

scientific article published on 4 April 2012

Secondary depression in severe anxiety disorders: a population-based cohort study in Denmark.

scientific article published on 14 May 2015

Segment-wise genome-wide association analysis identifies a candidate region associated with schizophrenia in three independent samples

scientific article

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

scientific article published on 16 February 2020

Significance Levels in Genome-Wide Interaction Analysis (GWIA)

article

Specific anxiety disorders and subsequent risk for bipolar disorder: a nationwide study.

scientific article published on June 2016

Striatal response to reward anticipation: evidence for a systems-level intermediate phenotype for schizophrenia

scientific article published in May 2014

Studies in humans and mice implicate neurocan in the etiology of mania

scientific article

Supporting evidence for LRRTM1 imprinting effects in schizophrenia.

scientific article

Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function

scientific article

Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

scientific article

The 5-HTTLPR Polymorphism Affects Network-Based Functional Connectivity in the Visual-Limbic System in Healthy Adults

scientific article published on 07 June 2017

The Anorexia Nervosa Genetics Initiative: Overview and Methods

article

The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations

scientific article published on 04 May 2009

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

scientific article

The anorexia nervosa genetics initiative (ANGI): Overview and methods

article

The association between neonatal vitamin D status and risk of schizophrenia

scientific article published in Scientific Reports

The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia: findings from a large German case-control and family-based sample

scientific article published on 19 July 2010

The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia

scientific article published on 24 March 2011

The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion

scientific article

The influence of polygenic risk scores on the association between infections and schizophrenia

VATER/VACTERL association: identification of seven new twin pairs, a systematic review of the literature, and a classical twin analysis

scientific article

Whole-genome association analysis of treatment response in obsessive-compulsive disorder.

scientific article published on 31 March 2015

XRCC5 as a risk gene for alcohol dependence: evidence from a genome-wide gene-set-based analysis and follow-up studies in Drosophila and humans

scientific article

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