List of works - Darina Czamara

"DNA Methylation signatures in panic disorder".

scientific article published on 18 December 2017

127. The Epigenetic Clock at Birth: Associations With Maternal Antenatal Depression and Child Psychiatric Problems

141. FOXO1, A2M and TGFB1: Three Novel Genes Predicting Depression in Gene X Environment Interactions Are Identified Using Cross-Species and Cross-Tissues Transcriptomic and Mirnomic Analyses

article

16.4 EFFECT OF GENOTYPE AND EARLY ADVERSITY ENVIRONMENT ON DNA METHYLATION.

scientific article published in April 2018

566. Acute Psychosocial Stress Impacts the Hemodynamic Response latency: A Novel Brain Phenotype that Relates to Markers of Acute and Chronic Stress

scientific article published on 29 April 2017

A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder

scientific article published on 17 April 2015

A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes

scientific article published on 22 April 2020

A mega-analysis of genome-wide association studies for major depressive disorder

scientific article

A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders

scientific article published on 21 November 2020

An epigenetic clock for gestational age at birth based on blood methylation data

scientific article

Analysis of IL12B gene variants in inflammatory bowel disease

scientific article

Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis

scientific article published on 12 November 2020

Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth

scientific article

CEACAM6 gene variants in inflammatory bowel disease

scientific article (publication date: 29 April 2011)

Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study

scientific article published on 26 October 2021

Children with ADHD symptoms have a higher risk for reading, spelling and math difficulties in the GINIplus and LISAplus cohort studies

scientific article

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium

scientific article published on 13 September 2017

Connecting Anxiety and Genomic Copy Number Variation: A Genome-Wide Analysis in CD-1 Mice

scientific article

Cord blood DNA methylation reflects cord blood C-reactive protein levels but not maternal levels: a longitudinal study and meta-analysis

scientific article published on 30 April 2020

DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

scientific article published on 25 November 2020

DNA methylation levels are associated with CRF receptor antagonist treatment outcome in women with post-traumatic stress disorder

scientific article published on 03 November 2018

Dilution of candidates: the case of iron-related genes in restless legs syndrome

scientific article published on 29 August 2012

Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms: A Genetic Correlation and 2-Sample Mendelian Randomization Study

scientific article published on 20 October 2020

EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units

scientific article

Epigenetic clock at birth and psychiatric problems during early childhood

scholarly article by Anna Suarez et al published September 2017 in Psychoneuroendocrinology

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

scientific article published on 02 March 2020

Exposure-induced changes of plasma metabolome and gene expression in patients with panic disorder

scientific article published on 02 August 2019

FoxO1, A2M, and TGF-β1: three novel genes predicting depression in gene X environment interactions are identified using cross-species and cross-tissues transcriptomic and miRNomic analyses.

scientific article published on 4 January 2018

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

scientific article published in June 2015

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression

scientific article published on 18 July 2020

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia

scientific article published on 11 February 2019

Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1

scientific journal article

Genome-wide association study of antidepressant treatment-emergent suicidal ideation

scientific article published on 26 October 2011

Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression

scientific article published on 11 November 2019

Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia

scientific article published on 14 October 2020

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

scientific article

Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation

scientific article published on 09 August 2019

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns

scientific article published on 24 June 2019

IRGM variants and susceptibility to inflammatory bowel disease in the German population

scientific article

Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus

scientific article published on 23 May 2019

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.

scientific article published on 11 June 2019

Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2

scientific article published in 2013

Investigation of MORC1 DNA methylation as biomarker of early life stress and depressive symptoms

scientific article published on 26 October 2019

MEIS1 and BTBD9: genetic association with restless leg syndrome in end stage renal disease

scientific article

Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium

scientific article published on 10 October 2019

Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation

scientific article published on 07 January 2021

Maternal depression during pregnancy and epigenetic age in their newborns: The PREDO study

scholarly article by Anna Suarez et al published September 2016 in Psychoneuroendocrinology

Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the Pregnancy And Childhood Epigenetics Consortium

scientific article published on 17 December 2020

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

article

Methodological challenges in constructing DNA methylation risk scores

scientific article published on 22 July 2019

Multi-omics analysis identifies mitochondrial pathways associated with anxiety-related behavior

scientific article published on 26 September 2019

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation

scientific article published on 17 June 2016

PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites

scientific article

PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Colitis Supporting a Common Genetic Disease Background ⬇️

scientific article published on March 21, 2012

Polygenic Risk: Predicting Depression Outcomes in Clinical and Epidemiological Cohorts of Youths

scientific article published on 05 April 2019

Polygenic prediction of the risk of perinatal depressive symptoms

scientific article published on 05 July 2020

Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes

scientific article

Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach

scientific article

Rare variants in PLXNA4 and Parkinson's disease

scientific article

Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon

scientific journal article

Sex-related differential response to dexamethasone in endocrine and immune measures in depressed in-patients and healthy controls

scientific article published on 3 January 2018

Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation

scientific article published on 27 January 2021

Stable longitudinal associations of family income with children's hippocampal volume and memory persist after controlling for polygenic scores of educational attainment

scientific article published on 17 October 2019

Supportive evidence for FOXP1, BARX1, and FOXF1 as genetic risk loci for the development of esophageal adenocarcinoma

scientific article

The Epigenetic Clock at Birth: Associations With Maternal Antenatal Depression and Child Psychiatric Problems

article by Anna Suarez et al published May 2018 in Journal of the American Academy of Child and Adolescent Psychiatry

The NOD2 Single Nucleotide Polymorphisms rs2066843 and rs2076756 Are Novel and Common Crohn's Disease Susceptibility Gene Variants ⬇️

scientific article published on December 30, 2010

The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells

scientific article published on 14 October 2019

The Role of Osteopontin (OPN/SPP1) Haplotypes in the Susceptibility to Crohn's Disease ⬇️

scientific article published on December 29, 2011

The biological classification of mental disorders (BeCOME) study: a protocol for an observational deep-phenotyping study for the identification of biological subtypes

scientific article published on 11 May 2020

The brain's hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers

article published in the Proceedings of the National Academy of Sciences of the United States of America

The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety

scientific article

The epigenetic clock and pubertal, neuroendocrine, psychiatric, and cognitive outcomes in adolescents

scientific article published on 18 July 2018

The neuronal transporter gene SLC6A15 confers risk to major depression

scientific article

Time-dependent effects of dexamethasone plasma concentrations on glucocorticoid receptor challenge tests

scientific article published on 14 April 2016

Treatment response classes in major depressive disorder identified by model-based clustering and validated by clinical prediction models

scientific article published on 05 August 2019

List of works by Darina Czamara

"DNA Methylation signatures in panic disorder".

127. The Epigenetic Clock at Birth: Associations With Maternal Antenatal Depression and Child Psychiatric Problems

141. FOXO1, A2M and TGFB1: Three Novel Genes Predicting Depression in Gene X Environment Interactions Are Identified Using Cross-Species and Cross-Tissues Transcriptomic and Mirnomic Analyses

16.4 EFFECT OF GENOTYPE AND EARLY ADVERSITY ENVIRONMENT ON DNA METHYLATION.

566. Acute Psychosocial Stress Impacts the Hemodynamic Response latency: A Novel Brain Phenotype that Relates to Markers of Acute and Chronic Stress

A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder

A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes

A mega-analysis of genome-wide association studies for major depressive disorder

A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders

An epigenetic clock for gestational age at birth based on blood methylation data

Analysis of IL12B gene variants in inflammatory bowel disease

Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis

Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth

CEACAM6 gene variants in inflammatory bowel disease

Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study

Children with ADHD symptoms have a higher risk for reading, spelling and math difficulties in the GINIplus and LISAplus cohort studies

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium

Connecting Anxiety and Genomic Copy Number Variation: A Genome-Wide Analysis in CD-1 Mice

Cord blood DNA methylation reflects cord blood C-reactive protein levels but not maternal levels: a longitudinal study and meta-analysis

DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

DNA methylation levels are associated with CRF receptor antagonist treatment outcome in women with post-traumatic stress disorder

Dilution of candidates: the case of iron-related genes in restless legs syndrome

Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms: A Genetic Correlation and 2-Sample Mendelian Randomization Study

EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units

Epigenetic clock at birth and psychiatric problems during early childhood

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

Exposure-induced changes of plasma metabolome and gene expression in patients with panic disorder

FoxO1, A2M, and TGF-β1: three novel genes predicting depression in gene X environment interactions are identified using cross-species and cross-tissues transcriptomic and miRNomic analyses.

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia

Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1

Genome-wide association study of antidepressant treatment-emergent suicidal ideation

Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression

Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns

IRGM variants and susceptibility to inflammatory bowel disease in the German population

Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus

Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.

Intestinal DMBT1 expression is modulated by Crohn's disease-associated IL23R variants and by a DMBT1 variant which influences binding of the transcription factors CREB1 and ATF-2

Investigation of MORC1 DNA methylation as biomarker of early life stress and depressive symptoms

MEIS1 and BTBD9: genetic association with restless leg syndrome in end stage renal disease

Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium

Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation

Maternal depression during pregnancy and epigenetic age in their newborns: The PREDO study

Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the Pregnancy And Childhood Epigenetics Consortium

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

Methodological challenges in constructing DNA methylation risk scores

Multi-omics analysis identifies mitochondrial pathways associated with anxiety-related behavior

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation

PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites

PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Colitis Supporting a Common Genetic Disease Background ⬇️

Polygenic Risk: Predicting Depression Outcomes in Clinical and Epidemiological Cohorts of Youths

Polygenic prediction of the risk of perinatal depressive symptoms

Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes

Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach

Rare variants in PLXNA4 and Parkinson's disease

Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon

Sex-related differential response to dexamethasone in endocrine and immune measures in depressed in-patients and healthy controls

Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation

Stable longitudinal associations of family income with children's hippocampal volume and memory persist after controlling for polygenic scores of educational attainment

Supportive evidence for FOXP1, BARX1, and FOXF1 as genetic risk loci for the development of esophageal adenocarcinoma

The Epigenetic Clock at Birth: Associations With Maternal Antenatal Depression and Child Psychiatric Problems

The NOD2 Single Nucleotide Polymorphisms rs2066843 and rs2076756 Are Novel and Common Crohn's Disease Susceptibility Gene Variants ⬇️

The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells

The Role of Osteopontin (OPN/SPP1) Haplotypes in the Susceptibility to Crohn's Disease ⬇️

The biological classification of mental disorders (BeCOME) study: a protocol for an observational deep-phenotyping study for the identification of biological subtypes

The brain's hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers

The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety

The epigenetic clock and pubertal, neuroendocrine, psychiatric, and cognitive outcomes in adolescents

The neuronal transporter gene SLC6A15 confers risk to major depression

Time-dependent effects of dexamethasone plasma concentrations on glucocorticoid receptor challenge tests

Treatment response classes in major depressive disorder identified by model-based clustering and validated by clinical prediction models

Variably methylated regions in the newborn epigenome: environmental, genetic and combined influences