List of works - Josef Anrather

Abeta-induced vascular oxidative stress and attenuation of functional hyperemia in mouse somatosensory cortex

scientific article published in March 2004

Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals

scientific article published on 26 January 2006

Angiotensin II attenuates functional hyperemia in the mouse somatosensory cortex

scientific article

Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals

scientific journal article

Angiotensin II slow-pressor hypertension enhances NMDA currents and NOX2-dependent superoxide production in hypothalamic paraventricular neurons

scientific article published on 10 April 2013

Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca2+ currents in NTS neurons

scientific article

Angiotensin II-dependent hypertension requires cyclooxygenase 1-derived prostaglandin E2 and EP1 receptor signaling in the subfornical organ of the brain

scientific article published on 27 February 2012

Biological networks in ischemic tolerance - rethinking the approach to clinical conditioning

scientific article published on February 2013

COX-1-derived PGE2 and PGE2 type 1 receptors are vital for angiotensin II-induced formation of reactive oxygen species and Ca(2+) influx in the subfornical organ

scientific article published on 06 September 2013

Central cardiovascular circuits contribute to the neurovascular dysfunction in angiotensin II hypertension

scientific article published in April 2012

Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II.

scientific article published on 30 November 2006

Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus

scientific article

Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

scientific article published on 28 March 2016

Cyclooxygenase 1-derived prostaglandin E2 and EP1 receptors are required for the cerebrovascular dysfunction induced by angiotensin II.

scientific article

Endothelial CD36 Contributes to Postischemic Brain Injury by Promoting Neutrophil Activation via CSF3.

scientific article

Endothelin 1-dependent neurovascular dysfunction in chronic intermittent hypoxia

scientific article

Estrous cycle-dependent neurovascular dysfunction induced by angiotensin II in the mouse neocortex

scientific article

Exogenous NADPH increases cerebral blood flow through NADPH oxidase-dependent and -independent mechanisms

scientific article published on 12 August 2004

Hypertension enhances Aβ-induced neurovascular dysfunction, promotes β-secretase activity, and leads to amyloidogenic processing of APP

scientific article published on 29 April 2015

Hypo-phosphorylation leads to nuclear retention of NF-kappaB p65 due to impaired IkappaBalpha gene synthesis

scientific article

Immune interventions in stroke

scientific article

Immune mechanisms in cerebral ischemic tolerance

scientific article

Innate immunity receptor CD36 promotes cerebral amyloid angiopathy

scientific article published on 4 February 2013

Key role of CD36 in Toll-like receptor 2 signaling in cerebral ischemia.

scientific article

Key role of tissue plasminogen activator in neurovascular coupling

scientific journal article

Monoubiquitination of nuclear RelA negatively regulates NF-κB activity independent of proteasomal degradation

scientific article

NMDA receptor activation increases free radical production through nitric oxide and NOX2.

scientific article published on February 2009

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

scientific article

Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain

scientific article

Nuclear factor-kappaB activation and postischemic inflammation are suppressed in CD36-null mice after middle cerebral artery occlusion

scientific article published on February 2008

Prostaglandin E2 type 1 receptors contribute to neuronal apoptosis after transient forebrain ischemia

scientific article published on May 2013

Purinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: roles in the outcome of excitotoxic brain injury

scientific article

Regulation of nuclear factor κB (NF-κB) transcriptional activity via p65 acetylation by the chaperonin containing TCP1 (CCT)

scientific article

Reperfusion rather than ischemia drives the formation of ubiquitin aggregates after middle cerebral artery occlusion

scientific article

SUMO2/3 is associated with ubiquitinated protein aggregates in the mouse neocortex after middle cerebral artery occlusion

scientific article

Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta

scientific article

Site-specific Phosphorylation of the p65 Protein Subunit Mediates Selective Gene Expression by Differential NF-κB and RNA Polymerase II Promoter Recruitment ⬇️

scientific article published on October 25, 2012

Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1.

scientific article

Stroke research at a crossroad: asking the brain for directions

scientific article

Termination of NF-kappaB activity through a gammaherpesvirus protein that assembles an EC5S ubiquitin-ligase

scientific article

The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin

scientific article (publication date: May 2015)

The role of microglia and myeloid immune cells in acute cerebral ischemia

scientific article

The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation

scientific article published on 17 October 2015

cis-acting, element-specific transcriptional activity of differentially phosphorylated nuclear factor-kappa B.

scientific article

List of works by Josef Anrather

Abeta-induced vascular oxidative stress and attenuation of functional hyperemia in mouse somatosensory cortex

Angiotensin II attenuates endothelium-dependent responses in the cerebral microcirculation through nox-2-derived radicals

Angiotensin II attenuates functional hyperemia in the mouse somatosensory cortex

Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals

Angiotensin II slow-pressor hypertension enhances NMDA currents and NOX2-dependent superoxide production in hypothalamic paraventricular neurons

Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca2+ currents in NTS neurons

Angiotensin II-dependent hypertension requires cyclooxygenase 1-derived prostaglandin E2 and EP1 receptor signaling in the subfornical organ of the brain

Biological networks in ischemic tolerance - rethinking the approach to clinical conditioning

COX-1-derived PGE2 and PGE2 type 1 receptors are vital for angiotensin II-induced formation of reactive oxygen species and Ca(2+) influx in the subfornical organ

Central cardiovascular circuits contribute to the neurovascular dysfunction in angiotensin II hypertension

Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II.

Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus

Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

Cyclooxygenase 1-derived prostaglandin E2 and EP1 receptors are required for the cerebrovascular dysfunction induced by angiotensin II.

Endothelial CD36 Contributes to Postischemic Brain Injury by Promoting Neutrophil Activation via CSF3.

Endothelin 1-dependent neurovascular dysfunction in chronic intermittent hypoxia

Estrous cycle-dependent neurovascular dysfunction induced by angiotensin II in the mouse neocortex

Exogenous NADPH increases cerebral blood flow through NADPH oxidase-dependent and -independent mechanisms

Hypertension enhances Aβ-induced neurovascular dysfunction, promotes β-secretase activity, and leads to amyloidogenic processing of APP

Hypo-phosphorylation leads to nuclear retention of NF-kappaB p65 due to impaired IkappaBalpha gene synthesis

Immune interventions in stroke

Immune mechanisms in cerebral ischemic tolerance

Innate immunity receptor CD36 promotes cerebral amyloid angiopathy

Key role of CD36 in Toll-like receptor 2 signaling in cerebral ischemia.

Key role of tissue plasminogen activator in neurovascular coupling

Monoubiquitination of nuclear RelA negatively regulates NF-κB activity independent of proteasomal degradation

NMDA receptor activation increases free radical production through nitric oxide and NOX2.

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain

Nuclear factor-kappaB activation and postischemic inflammation are suppressed in CD36-null mice after middle cerebral artery occlusion

Prostaglandin E2 type 1 receptors contribute to neuronal apoptosis after transient forebrain ischemia

Purinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: roles in the outcome of excitotoxic brain injury

Regulation of nuclear factor κB (NF-κB) transcriptional activity via p65 acetylation by the chaperonin containing TCP1 (CCT)

Reperfusion rather than ischemia drives the formation of ubiquitin aggregates after middle cerebral artery occlusion

SUMO2/3 is associated with ubiquitinated protein aggregates in the mouse neocortex after middle cerebral artery occlusion

Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta

Site-specific Phosphorylation of the p65 Protein Subunit Mediates Selective Gene Expression by Differential NF-κB and RNA Polymerase II Promoter Recruitment ⬇️

Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1.

Stroke research at a crossroad: asking the brain for directions

Termination of NF-kappaB activity through a gammaherpesvirus protein that assembles an EC5S ubiquitin-ligase

The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin

The role of microglia and myeloid immune cells in acute cerebral ischemia

The ubiquitin ligase HERC3 attenuates NF-κB-dependent transcription independently of its enzymatic activity by delivering the RelA subunit for degradation

cis-acting, element-specific transcriptional activity of differentially phosphorylated nuclear factor-kappa B.