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List of works by Caroline Seynaeve

11q13 is a susceptibility locus for hormone receptor positive breast cancer

scientific article

19p13.1 is a triple-negative-specific breast cancer susceptibility locus

scientific article published on 13 February 2012

2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy

scientific article

5-HT3 receptor antagonists, a new approach in emesis: a review of ondansetron, granisetron and tropisetron

scientific article published in August 1991

7q21-rs6964587 and breast cancer risk: an extended case-control study by the Breast Cancer Association Consortium

scientific article

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium

scientific article published on 02 August 2012

A family history of breast cancer will not predict female early onset breast cancer in a population-based setting

scientific article

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium

scientific article

A metastasis of an adenocarcinoma in a BRCA1 mutation carrier, a diagnostic problem not solved by morphology alone

scientific article published in May 2004

A phase II study of ET-743/trabectedin ('Yondelis') for patients with advanced gastrointestinal stromal tumours

scientific article

A phase II study of epidoxorubicin in colorectal cancer and the use of cyclosporin-A in an attempt to reverse multidrug resistance

scientific article

A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients

scientific article published on 16 December 2015

A prospective study of the impact of genetic susceptibility testing for BRCA1/2 or HNPCC on family relationships

scientific article published on April 2007

A randomized phase III study comparing pegylated liposomal doxorubicin with capecitabine as first-line chemotherapy in elderly patients with metastatic breast cancer: results of the OMEGA study of the Dutch Breast Cancer Research Group BOOG

scientific article published on 6 February 2014

Abstract S4-06: HER2 status as predictive marker for AI vs Tam benefit: A TRANS-AIOG meta-analysis of 12129 patients from ATAC, BIG 1-98 and TEAM with centrally determined HER2

Adjuvant radiotherapy for primary breast cancer in BRCA1 and BRCA2 mutation carriers and risk of contralateral breast cancer with special attention to patients irradiated at younger age.

scientific article

Adverse effect on bone marrow protection of prechemotherapy granulocyte colony-stimulating factor support

scientific article

Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers

scientific article

Age-specific nonpersistence of endocrine therapy in postmenopausal patients diagnosed with hormone receptor-positive breast cancer: a TEAM study analysis

scientific article published on 30 December 2011

Altered clearance of unbound paclitaxel in elderly patients with metastatic breast cancer

scientific article published in January 2003

An 8-gene mRNA expression profile in circulating tumor cells predicts response to aromatase inhibitors in metastatic breast cancer patients

scientific article published on 18 February 2016

An international survey of surveillance schemes for unaffected BRCA1 and BRCA2 mutation carriers

scientific article

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers

scientific article

Association analysis identifies 65 new breast cancer risk loci.

scientific article published on 23 October 2017

Association between a germline OCA2 polymorphism at chromosome 15q13.1 and estrogen receptor-negative breast cancer survival

scientific article

Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study

scientific article

Association of risk-reducing surgery with cancer risks and mortality in BRCA mutation carriers

scientific article

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

scientific article

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

article by Xiang Shu et al published 1 October 2018 in International Journal of Epidemiology

Attitudes and distress levels in women at risk to carry a BRCA1/BRCA2 gene mutation who decline genetic testing

scientific article published in June 2003

Author Reply: Decision-Making Management of Women with a High Risk of Developing Breast and Ovarian Cancer

scientific article published on 9 April 2008

BRCA1-associated breast cancers present differently from BRCA2-associated and familial cases: long-term follow-up of the Dutch MRISC Screening Study

scientific article

BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer

scientific article published on 10 March 2017

Baseline comprehensive geriatric assessment is associated with toxicity and survival in elderly metastatic breast cancer patients receiving single-agent chemotherapy: results from the OMEGA study of the Dutch breast cancer trialists' group

scientific article

Body image and psychological distress after prophylactic mastectomy and breast reconstruction in genetically predisposed women: A prospective long-term follow-up study ⬇️

article by Mariska den Heijer et al published June 2012 in European Journal of Cancer

Body image issues after bilateral prophylactic mastectomy with breast reconstruction in healthy women at risk for hereditary breast cancer

article by Jessica P. Gopie et al published 8 December 2012 in Familial Cancer

Body mass index and breast cancer survival: a Mendelian randomization analysis

scientific article published in December 2017

Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations

scientific article published on 27 November 2013

Breast cancer after prophylactic bilateral mastectomy in women with a BRCA1 or BRCA2 mutation

scientific article

Breast cancer risk after salpingo-oophorectomy in healthy BRCA1/2 mutation carriers: revisiting the evidence for risk reduction

scientific article published on 18 March 2015

Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2

scientific article

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

scientific article

Breast cancer screening in high-risk women. Rotterdam Committee of Medical and Genetic Counseling

scientific article published in October 1999

Breast density as indicator for the use of mammography or MRI to screen women with familial risk for breast cancer (FaMRIsc): a multicentre randomized controlled trial

scientific article

CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer

scientific article

CHEK2*1100delC homozygosity in the Netherlands--prevalence and risk of breast and lung cancer

scientific article published on 08 May 2013

CHEK2-mutation in Dutch breast cancer families: expanding genetic testing for breast cancer

scientific article published in January 2015

CYP2D6 genotype in relation to hot flashes as tamoxifen side effect in a Dutch cohort of the tamoxifen exemestane adjuvant multinational (TEAM) trial

CYP2D6 genotype in relation to tamoxifen efficacy in a Dutch cohort of the tamoxifen exemestane adjuvant multinational (TEAM) trial

scientific article published on 11 July 2013

Chemosensitivity and outcome of BRCA1- and BRCA2-associated ovarian cancer patients after first-line chemotherapy compared with sporadic ovarian cancer patients

scientific article

Chemotherapy in metastasized breast carcinoma

scientific article published on July 25, 1998

Clinical correlates of low-risk variants in FGFR2, TNRC9, MAP3K1, LSP1 and 8q24 in a Dutch cohort of incident breast cancer cases

scientific article

Clinical experience of prophylactic mastectomy followed by immediate breast reconstruction in women at hereditary risk of breast cancer (HB(O)C) or a proven BRCA1 and BRCA2 germ-line mutation

scientific article published in September 2002

Cognitive functioning of postmenopausal breast cancer patients before adjuvant systemic therapy, and its association with medical and psychological factors

scientific article published on 24 December 2009

Combined treatment with buserelin and tamoxifen in premenopausal metastatic breast cancer: a randomized study

scientific article published on 01 June 2000

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

scientific article published on 2 November 2011

Common germline polymorphisms associated with breast cancer-specific survival

scientific article published on 22 April 2015

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium

scientific article

Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

scientific article

Comparison of individuals opting for BRCA1/2 or HNPCC genetic susceptibility testing with regard to coping, illness perceptions, illness experiences, family system characteristics and hereditary cancer distress

Contralateral breast cancer risk is influenced by the age at onset in BRCA1-associated breast cancer

scientific article published in August 2000

Controlling cancer chemotherapy-induced emesis ⬇️

scientific article published on October 18, 1991

Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

scientific article published in PLoS ONE

Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer

scientific article

Cytotoxic therapy for the elderly with metastatic breast cancer: a review on safety, pharmacokinetics and efficacy

scientific article

Dextromethorphan as a phenotyping test to predict endoxifen exposure in patients on tamoxifen treatment

scientific article

Diagnostic and therapeutic ionizing radiation and the risk of a first and second primary breast cancer, with special attention for BRCA1 and BRCA2 mutation carriers: a critical review of the literature

scientific article published on 08 December 2014

Distant disease-free interval, site of first relapse and post-relapse survival in BRCA1- and BRCA2-associated compared to sporadic breast cancer patients

scientific article

Do type 1 receptor tyrosine kinases inform treatment choice? A prospectively planned analysis of the TEAM trial

scientific article published on 03 October 2013

Dynamic prediction in breast cancer: proving feasibility in clinical practice using the TEAM trial.

scientific article

E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium.

scientific article published on 26 April 2018

Ecthyma gangrenosum caused by Pseudomonas aeruginosa in a patient with astrocytoma treated with chemotherapy

scientific article

Effectiveness of breast cancer surveillance in BRCA1/2 gene mutation carriers and women with high familial risk

scientific article published in February 2001

Effects of CYP Induction by Rifampicin on Tamoxifen Exposure

scientific article published on May 23, 2012

Effects of tamoxifen and exemestane on cognitive functioning of postmenopausal patients with breast cancer: results from the neuropsychological side study of the tamoxifen and exemestane adjuvant multinational trial

scientific article published on 8 February 2010

Elderly postmenopausal patients with breast cancer are at increased risk for distant recurrence: a tamoxifen exemestane adjuvant multinational study analysis

scientific article published on 20 December 2012

Estrogen receptor and progesterone receptor as predictive biomarkers of response to endocrine therapy: a prospectively powered pathology study in the Tamoxifen and Exemestane Adjuvant Multinational trial

scientific article

Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients

scientific article published on 24 October 2017

Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation

scientific article published in March 2018

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

scientific article

Exploring the course of psychological distress around two successive control visits in women at hereditary risk of breast cancer

Extended adjuvant aromatase inhibition after sequential endocrine therapy (DATA): a randomised, phase 3 trial

scientific article published on 11 October 2017

External validity of a trial comprised of elderly patients with hormone receptor-positive breast cancer

scientific article

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

scientific article published on February 2014

Factors affecting sensitivity and specificity of screening mammography and MRI in women with an inherited risk for breast cancer

scientific article

Familial versus Sporadic Breast Cancer: Different Treatments for Similar Tumors?

scientific article published in 2015

Fatigue and relating factors in high-risk breast cancer patients treated with adjuvant standard or high-dose chemotherapy: a longitudinal study

scientific article

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).

scientific article published on 07 September 2016

Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus

scientific article

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

scientific article published on 4 February 2015

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

article

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

scientific article published on 07 January 2020

Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer

scientific article

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

scientific article

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

scientific article

Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium

scientific article

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

scientific article published on 27 March 2013

GIST as the model of paradigm shift towards targeted therapy of solid tumors: update and perspective on trial design

scientific article

Genetic modifiers of CHEK2*1100delC-associated breast cancer risk

scientific article published on 06 October 2016

Genetic predisposition to in situ and invasive lobular carcinoma of the breast

scientific article

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade

scientific article

Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent

scientific article (publication date: August 2016)

Genome-wide association analysis identifies three new breast cancer susceptibility loci

scientific article published on 22 January 2012

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

scientific article

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

scientific article published in April 2013

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

scientific article (publication date: 2013)

Genome-wide association study of germline variants and breast cancer-specific mortality

scientific article published on 21 February 2019

Germline variants in the CYP19A1 gene are related to specific adverse events in aromatase inhibitor users: a substudy of Dutch patients in the TEAM trial

article

Global and focal brain volume in long-term breast cancer survivors exposed to adjuvant chemotherapy

scientific article

Global and focal white matter integrity in breast cancer survivors 20 years after adjuvant chemotherapy

scientific article published on 20 December 2012

Gynaecological sarcomas

scientific article

HER2 status predicts for upfront AI benefit: A TRANS-AIOG meta-analysis of 12,129 patients from ATAC, BIG 1-98 and TEAM with centrally determined HER2.

scientific article published on 08 May 2017

Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization

scientific article

Heterogeneous HER2 gene amplification: impact on patient outcome and a clinically relevant definition

scientific article

High satisfaction rates in women after DIEP flap breast reconstruction

scientific article published on 25 November 2008

High-dose chemotherapy in adult sarcomas: no standard yet.

scientific article published in February 1999

Hypersensitivity reactions to CHIP.

scientific article published in June 1990

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

scientific article

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

scientific article

Identification of novel genetic markers of breast cancer survival

scientific article published on 18 April 2015

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers

scientific article published on 23 December 2015

Impact of screening for breast cancer in high-risk women on health-related quality of life

scientific article published on July 2004

Improved insight into resistance mechanisms to imatinib in gastrointestinal stromal tumors: a basis for novel approaches and individualization of treatment

scientific article

Improved overall survival after contralateral risk-reducing mastectomy in BRCA1/2 mutation carriers with a history of unilateral breast cancer: a prospective analysis

scientific article published on 8 July 2014

Incidental findings on brain Magnetic Resonance Imaging in long-term survivors of breast cancer treated with adjuvant chemotherapy

scientific article

Influence of semi-quantitative oestrogen receptor expression on adjuvant endocrine therapy efficacy in ductal and lobular breast cancer - a TEAM study analysis

scientific article

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

scientific article

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer

scientific article

Ipsilateral breast tumour recurrence in hereditary breast cancer following breast-conserving therapy

scientific article published in May 2004

Large regional differences in the frequency of distinct BRCA1/BRCA2 mutations in 517 Dutch breast and/or ovarian cancer families

scientific article

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

scientific article published in December 2015

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

scientific article

Late effects of adjuvant chemotherapy for adult onset non-CNS cancer; cognitive impairment, brain structure and risk of dementia

scientific article published on 13 June 2013

Late effects of adjuvant chemotherapy for breast cancer on fine motor function

scientific article published on 9 March 2015

Long-term psychological impact of carrying a BRCA1/2 mutation and prophylactic surgery: a 5-year follow-up study

scientific article published in October 2003

Long‐term psychological distress in women at risk for hereditary breast cancer adhering to regular surveillance: a risk profile ⬇️

scientific article published on February 7, 2012

Low Dose Methotrexate and Vinblastine, Given Weekly to Patients With Desmoid Tumours, is Associated With Major Toxicity

scientific article

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

scientific article

Lower mitotic activity in BRCA1/2-associated primary breast cancers occurring after risk-reducing salpingo-oophorectomy

scientific article published on 14 January 2014

MDM2 promoter SNP344T>A (rs1196333) status does not affect cancer risk

scientific article

MUTYH gene variants and breast cancer in a Dutch case–control study

scientific article

Mammostrat as an immunohistochemical multigene assay for prediction of early relapse risk in the tamoxifen versus exemestane adjuvant multicenter trial pathology study

scientific article published on 8 October 2012

Menopausal status and adjuvant hormonal therapy for breast cancer patients: A practical guideline ⬇️

scientific article published on July 12, 2012

MicroRNA related polymorphisms and breast cancer risk

scientific article

Micrometastases or isolated tumor cells and the outcome of breast cancer.

scientific article

Minimal impact of adjuvant exemestane or tamoxifen treatment on mammographic breast density in postmenopausal breast cancer patients: A Dutch TEAM trial analysis

article published in 2014

Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls

scientific article

Molecular determination of the clonal relationships between multiple tumors in BRCA1/2-associated breast and/or ovarian cancer patients is clinically relevant

scientific article published on 9 September 2016

Molecular stratification of early breast cancer identifies drug targets to drive stratified medicine

scientific article

Most women recover from psychological distress after postoperative complications following implant or DIEP flap breast reconstruction: A prospective long-term follow-up study

scientific article

Multidisciplinary treatment of superior sulcus (Pancoast) tumors

scientific article published on April 26, 1997

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Mutational analysis of PI3K/AKT signaling pathway in tamoxifen exemestane adjuvant multinational pathology study.

scientific article published in September 2014

Neuropsychological functioning in postmenopausal breast cancer patients treated with tamoxifen or exemestane after AC-chemotherapy: cross-sectional findings from the neuropsychological TEAM-side study

scientific article published on January 2009

Neuropsychological performance in survivors of breast cancer more than 20 years after adjuvant chemotherapy

scientific article published on 27 February 2012

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

scientific article published on 29 March 2009

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

No evidence that GATA3 rs570613 SNP modifies breast cancer risk

scientific article published on 11 December 2008

Novel endocrine therapies in breast cancer

scientific article published on January 1996

Occult cancer in the fallopian tube in patients with a BRCA-1 germline mutation

scientific article published on 01 November 2001

Ondansetron compared with high-dose metoclopramide in prophylaxis of acute and delayed cisplatin-induced nausea and vomiting. A multicenter, randomized, double-blind, crossover study.

scientific article

Ondansetron in the prophylaxis of nausea and vomiting induced by cisplatin

scientific article published on 01 January 1990

One year follow-up of women opting for presymptomatic testing for BRCA1 and BRCA2: emotional impact of the test outcome and decisions on risk management (surveillance or prophylactic surgery).

scientific article published in May 2002

Outcome of BRCA1- compared with BRCA2-associated ovarian cancer: a nationwide study in the Netherlands

scientific article published on 29 March 2013

Outcome of ovarian cancer after breast cancer in BRCA1 and BRCA2 mutation carriers

scientific article published on 18 October 2016

Outcome of surveillance and prophylactic salpingo-oophorectomy in asymptomatic women at high risk for ovarian cancer

scientific article published in May 2005

Outcomes of first-line chemotherapy in patients with advanced or metastatic leiomyosarcoma of uterine and non-uterine origin

scientific article

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016

PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1.

scientific article published on 12 October 2017

Passive coping and psychological distress in women adhering to regular breast cancer surveillance

scientific article published in September 2007

Pathophysiology of cytotoxic drug-induced emesis: far from crystal-clear ⬇️

scientific article published on February 22, 1991

Patients' preferences for breast reconstruction: a discrete choice experiment

scientific article published on 31 May 2010

Patterns of care in Dutch postmenopausal patients with hormone-sensitive early breast cancer participating in the Tamoxifen Exemestane Adjuvant Multinational (TEAM) trial

scientific article published on 29 October 2009

Phase II study of combining vinblastine and cyclosporin-A to circumvent multidrug resistance in renal cell cancer

scientific article

Phase II study of miltefosine 6% solution as topical treatment of skin metastases in breast cancer patients

scientific article published in November 2000

Phase II study of mitozolomide in advanced soft tissue sarcoma of adults: the EORTC Soft Tissue and Bone Sarcoma Group

scientific article published on January 1, 1992

Phase II study of weekly gemcitabine in patients with metastatic breast cancer relapsing or failing both an anthracycline and a taxane

scientific article published in March 2001

Phase II to III study comparing doxorubicin and docetaxel with fluorouracil, doxorubicin, and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: results of a Dutch Community Setting Trial for the Clinical Trial Gr

scientific article

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

scientific article

Possible consequences of applying guidelines to healthy women with a family history of breast cancer

scientific article published in August 2003

Practice guideline 'Diagnostic techniques for soft tissue tumours and treatment of soft tissue sarcomas (revision)'

scientific article

Prediction of breast cancer risk based on profiling with common genetic variants

scientific article published on 8 April 2015

Presymptomatic DNA testing and prophylactic surgery in families with a BRCA1 or BRCA2 mutation

scientific article published on 01 June 2000

Prevalence of cerebral small-vessel disease in long-term breast cancer survivors exposed to both adjuvant radiotherapy and chemotherapy

scientific article published on 5 January 2015

Prevalence of the variant allele rs61764370 T>G in the 3'UTR of KRAS among Dutch BRCA1, BRCA2 and non-BRCA1/BRCA2 breast cancer families

scientific article

Preventive surgical prcedures for inherited risk of breast cancer

scientific article published in November 2005

Primitive neuroectodermal tumor of the cervix uteri: a case report -- changing concepts in therapy

scientific article published in September 2005

Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor

scientific article published on 17 October 2016

Prognostic factors for hereditary cancer distress six months after BRCA1/2 or HNPCC genetic susceptibility testing

Prognostic significance of germline BRCA2 mutations in hereditary breast cancer patients

scientific article published in November 2000

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

scientific article published on 18 October 2016

Prophylactic mastectomy in BRCA1/2 mutation carriers and women at risk of hereditary breast cancer: long-term experiences at the Rotterdam Family Cancer Clinic

scientific article

Prospective study of long-term impact of adjuvant high-dose and conventional-dose chemotherapy on health-related quality of life

scientific article published on December 2007

Psychological distress and breast self-examination frequency in women at increased risk for hereditary or familial breast cancer

scientific article published in January 2003

Psychological distress in women at increased risk for breast cancer: the role of risk perception

article by Silvia van Dooren et al published September 2004 in European Journal of Cancer

Psychological distress in women at risk for hereditary breast cancer: the role of family communication and perceived social support

scientific article published on 5 October 2010

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

scientific article published on 10 April 2018

Quality of life in relation to tamoxifen or exemestane treatment in postmenopausal breast cancer patients: a Tamoxifen Exemestane Adjuvant Multinational (TEAM) Trial side study ⬇️

scientific article published on March 28, 2012

RAD51B in Familial Breast Cancer

scientific article

Radiation Dose-Response For Risk Of Myocardial Infarction In Breast Cancer Survivors

article published in 2018

Randomised phase II trial of carboplatin and iproplatin in advanced urothelial cancer ⬇️

scientific article published on January 1, 1991

Randomized Phase II Study of Docetaxel Versus Doxorubicin in First- and Second-Line Chemotherapy for Locally Advanced or Metastatic Soft Tissue Sarcomas in Adults: A Study of the European Organization for Research and Treatment of Cancer Soft Tissue

article

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

scientific article

Relevance and efficacy of breast cancer screening in BRCA1 and BRCA2 mutation carriers above 60 years: a national cohort study

scientific article published on 20 May 2014

Relevant factors for the optimal duration of extended endocrine therapy in early breast cancer

scientific article

Relevant impact of central pathology review on nodal classification in individual breast cancer patients ⬇️

scientific article published on April 11, 2012

Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study.

scientific article published on 7 November 2017

Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.

scientific article published on 30 June 2009

Satisfaction with prophylactic mastectomy and breast reconstruction in genetically predisposed women

scientific article published in May 2006

Self‐reported cognitive functioning in postmenopausal breast cancer patients before and during endocrine treatment: findings from the neuropsychological TEAM side‐study ⬇️

scientific article published on February 23, 2011

Sensitivity to first-line chemotherapy for metastatic breast cancer in BRCA1 and BRCA2 mutation carriers

scientific article

Sensitivity to systemic therapy for metastatic breast cancer in CHEK2 1100delC mutation carriers

scientific article

Severe akathisia as a side effect of metoclopramide ⬇️

scientific article published on October 30, 2010

Slow accrual of elderly patients with metastatic breast cancer in the Dutch multicentre OMEGA study ⬇️

scientific article published on January 8, 2013

Specific adverse events predict survival benefit in patients treated with tamoxifen or aromatase inhibitors: an international tamoxifen exemestane adjuvant multinational trial analysis

scientific article published on 22 April 2013

Standard psychological consultations and follow up for women at increased risk of hereditary breast cancer considering prophylactic mastectomy

scientific article

Substantial breast cancer risk reduction and potential survival benefit after bilateral mastectomy when compared with surveillance in healthy BRCA1 and BRCA2 mutation carriers: a prospective analysis

scientific article

Survival and contralateral breast cancer in CHEK2 1100delC breast cancer patients: impact of adjuvant chemotherapy

scientific article

Survival and prognostic factors in BRCA1-associated breast cancer

scientific article published in December 2005

Survival and tumour characteristics of breast-cancer patients with germline mutations of BRCA1 ⬇️

scientific article published on January 31, 1998

Survival in hereditary breast cancer associated with germline mutations of BRCA2.

scientific article published in November 1999

Tailoring breast cancer therapy to genetic status

scientific article published in May 2005

Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers

scientific article published on 05 August 2013

Targeted therapy: ready for prime time?

scientific article published in January 2004

The 5-HT3 receptor antagonist ondansetron re-establishes control in refractory emesis induced by non-cisplatin chemotherapy

scientific article

The Distress Thermometer assessed in women at risk of developing hereditary breast cancer

scientific article published in October 2009

The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians

article

The common sense model of self-regulation and psychological adjustment to predictive genetic testing: a prospective study

article

The contribution of self-esteem and self-concept in psychological distress in women at risk of hereditary breast cancer

The course of distress in women at increased risk of breast and ovarian cancer due to an (identified) genetic susceptibility who opt for prophylactic mastectomy and/or salpingo-oophorectomy

scientific article published on 13 November 2006

The efficacy of taxane chemotherapy for metastatic breast cancer in BRCA1 and BRCA2 mutation carriers

scientific article

The impact of CYP2D6-predicted phenotype on tamoxifen treatment outcome in patients with metastatic breast cancer

scientific article

The impact of having relatives affected with breast cancer on psychological distress in women at increased risk for hereditary breast cancer

The impact of social and personal resources on psychological distress in women at risk for hereditary breast cancer

scientific article published on 2 December 2010

The influence of insulin-like Growth Factor-1-Receptor expression and endocrine treatment on clinical outcome of postmenopausal hormone receptor positive breast cancer patients: A Dutch TEAM substudy analysis

scientific article published on 31 October 2015

The pharmacologic basis of ifosfamide use in adult patients with advanced soft tissue sarcomas

scientific article

The prognostic and predictive value of Tregs and tumor immune subtypes in postmenopausal, hormone receptor-positive breast cancer patients treated with adjuvant endocrine therapy: a Dutch TEAM study analysis

scientific article

The reason for confining the use of adjuvant chemotherapy in soft tissue sarcoma to the investigational setting

scientific article published in October 1999

The risk of primary and contralateral breast cancer after ovarian cancer in BRCA1/BRCA2 mutation carriers: Implications for counseling

scientific article

The role of genetic breast cancer susceptibility variants as prognostic factors

scientific article

Time dependence of biomarkers: non-proportional effects of immunohistochemical panels predicting relapse risk in early breast cancer

scientific article

Timing of risk reducing mastectomy in breast cancer patients carrying a BRCA1/2 mutation: retrospective data from the Dutch HEBON study

scientific article

Toxicity of (neo)adjuvant chemotherapy for BRCA1- and BRCA2-associated breast cancer

scientific article published on 9 April 2016

Tumor characteristics and detection method in the MRISC screening program for the early detection of hereditary breast cancer

scientific article

Tumor-associated inflammation as a potential prognostic tool in BRCA1/2-associated breast cancer

scientific article published on 15 November 2014

Tumour characteristics and prognosis of breast cancer patients carrying the germline CHEK2*1100delC variant

scientific article

Tumour characteristics, survival and prognostic factors of hereditary breast cancer from BRCA2-, BRCA1- and non-BRCA1/2 families as compared to sporadic breast cancer cases

scientific article

Use of Genetic Testing and Prophylactic Mastectomy and Oophorectomy in Women With Breast or Ovarian Cancer From Families With a BRCA1 or BRCA2 Mutation ⬇️

scientific article published on May 1, 2003

Using single-agent therapy in adult patients with advanced soft tissue sarcoma can still be considered standard care

scientific article published in November 2005

Validation of the IHC4 Breast Cancer Prognostic Algorithm Using Multiple Approaches on the Multinational TEAM Clinical Trial

scientific article published in January 2016

Variations in locoregional therapy in postmenopausal patients with early breast cancer treated in different countries

scientific article published on May 2010

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