List of works - Adrien Six

Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis

scientific article published in December 2011

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients

scientific article published on 26 January 2015

Restoration of regulatory and effector T cell balance and B cell homeostasis in systemic lupus erythematosus patients through vitamin D supplementation

scientific article published on 17 October 2012

Interleukin-21 modulates Th1 and Th17 responses in giant cell arteritis

article

The past, present, and future of immune repertoire biology - the rise of next-generation repertoire analysis

scientific article

Teleost fish mount complex clonal IgM and IgT responses in spleen upon systemic viral infection

scientific article (publication date: 2013)

The astonishing diversity of Ig classes and B cell repertoires in teleost fish

scientific article (publication date: 2013)

Preserving the B-cell compartment favors operational tolerance in human renal transplantation

scientific article

The expansion and selection of T cell receptor alpha beta intestinal intraepithelial T cell clones

scientific article published on 01 April 1996

Regulatory CD4+ CD25+ Foxp3+ T cells expand during experimental Plasmodium infection but do not prevent cerebral malaria

scientific article published on 19 January 2007

Behçet's disease physiopathology: a contemporary review

scientific article published on 12 February 2016

T follicular helper and T follicular regulatory cells have different TCR specificity.

scientific article published on 21 April 2017

Ontogeny of the immune system: gamma/delta and alpha/beta T cells migrate from thymus to the periphery in alternating waves

scientific article

HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation

scientific article published on 26 October 2015

Microorganisms linked to inflammatory bowel disease-associated dysbiosis differentially impact host physiology in gnotobiotic mice.

scientific article published on 28 July 2015

Phenotypic and functional similarity of gut intraepithelial and systemic T cells in a teleost fish

scientific article published on 01 April 2006

Massive expansion of regulatory T-cells following interleukin 2 treatment during a phase I-II dendritic cell-based immunotherapy of metastatic renal cancer.

scientific article published in September 2009

ISEApeaks: an Excel platform for GeneScan and Immunoscope data retrieval, management and analysis.

scientific article

Genetic structure of a wide-spectrum chicken gene pool

scientific article published on 3 June 2009

Characterization of avian T-cell receptor gamma genes

scientific article published on December 1996

T cell diversity and TcR repertoires in teleost fish

scientific article published on 06 September 2010

New perspectives for large-scale repertoire analysis of immune receptors

scientific article published on 14 February 2008

Systems biology in vaccine design

scientific article published on December 21, 2011

Th1 response and systemic treg deficiency in inclusion body myositis.

scientific article

TCR sequences and tissue distribution discriminate the subsets of naïve and activated/memory Treg cells in mice

scientific article

A profound alteration of blood TCRB repertoire allows prediction of cerebral malaria

scientific article published in October 2004

Epigenetic regulations in the IFNγ signalling pathway: IFNγ-mediated MHC class I upregulation on tumour cells is associated with DNA demethylation of antigen-presenting machinery genes.

scientific article published on August 2014

Identification of an endogenous mammary tumor virus involved in the clonal deletion of V beta 2 T cells.

scientific article published on November 1993

Diversity, molecular characterization and expression of T cell receptor γ in a teleost fish, the sea bass (Dicentrarchus labrax, L).

scientific article

Clinical-grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene

scientific article published in August 2008

New methods and software tools for high throughput CDR3 spectratyping. Application to T lymphocyte repertoire modifications during experimental malaria.

scientific article published in July 2003

Broadened T-cell repertoire diversity in ivIg-treated SLE patients is also related to the individual status of regulatory T-cells

scientific article

Half of the T-cell repertoire combinatorial diversity is genetically determined in humans and humanized mice.

scientific article published on 20 December 2011

High-resolution repertoire analysis reveals a major bystander activation of Tfh and Tfr cells

article published in the Proceedings of the National Academy of Sciences of the United States of America

Mechanisms of the natural reactivity of lymphocytes from noninfected individuals to membrane-associated Leishmania infantum antigens

scientific article

State-transition diagrams for biologists

scientific article

Contrasted TCRβ diversity of CD8+ and CD8- T cells in rainbow trout

scientific article

Endogenous TCR recombination in TCR Tg single RAG-deficient mice uncovered by robust in vivo T cell activation and selection

scientific article

TCR repertoire dynamics in the pancreatic lymph nodes of non-obese diabetic (NOD) mice at the time of disease initiation

scientific article published on 08 May 2008

Serum biomarker signature identifies patients with B-cell non-Hodgkin lymphoma associated with cryoglobulinemia vasculitis in chronic HCV infection

scientific article

A novel strategy for molecular signature discovery based on independent component analysis.

scientific article

Dynamical and Mechanistic Reconstructive Approaches of T Lymphocyte Dynamics: Using Visual Modeling Languages to Bridge the Gap between Immunologists, Theoreticians, and Programmers

scientific article published on October 2013

A unique CD8(+) T lymphocyte signature in pediatric type 1 diabetes.

scientific article published on 15 June 2016

Cutting edge: CD4-independent development of functional FoxP3+ regulatory T cells.

scientific article published in October 2009

Immunomonitoring

article from 2013

Germline genomic structure of the B10.A mouse Tcra-V2 gene subfamily

scientific article published in January 1996

GeVaDSs - decision support system for novel Genetic Vaccine development process

scientific article

A conserved sequence in the mouse variable T cell receptor alpha recombination signal sequence 23-bp spacer can affect recombination.

scientific article published on August 2004

Vaccinomics

A TCRβ Repertoire Signature Can Predict Experimental Cerebral Malaria

scientific article published on 4 February 2016

List of works by Adrien Six

Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis

Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients

Restoration of regulatory and effector T cell balance and B cell homeostasis in systemic lupus erythematosus patients through vitamin D supplementation

Interleukin-21 modulates Th1 and Th17 responses in giant cell arteritis

The past, present, and future of immune repertoire biology - the rise of next-generation repertoire analysis

Teleost fish mount complex clonal IgM and IgT responses in spleen upon systemic viral infection

The astonishing diversity of Ig classes and B cell repertoires in teleost fish

Preserving the B-cell compartment favors operational tolerance in human renal transplantation

The expansion and selection of T cell receptor alpha beta intestinal intraepithelial T cell clones

Regulatory CD4+ CD25+ Foxp3+ T cells expand during experimental Plasmodium infection but do not prevent cerebral malaria

Behçet's disease physiopathology: a contemporary review

T follicular helper and T follicular regulatory cells have different TCR specificity.

Ontogeny of the immune system: gamma/delta and alpha/beta T cells migrate from thymus to the periphery in alternating waves

HIV-Infected Spleens Present Altered Follicular Helper T Cell (Tfh) Subsets and Skewed B Cell Maturation

Microorganisms linked to inflammatory bowel disease-associated dysbiosis differentially impact host physiology in gnotobiotic mice.

Phenotypic and functional similarity of gut intraepithelial and systemic T cells in a teleost fish

Massive expansion of regulatory T-cells following interleukin 2 treatment during a phase I-II dendritic cell-based immunotherapy of metastatic renal cancer.

ISEApeaks: an Excel platform for GeneScan and Immunoscope data retrieval, management and analysis.

Genetic structure of a wide-spectrum chicken gene pool

Characterization of avian T-cell receptor gamma genes

T cell diversity and TcR repertoires in teleost fish

New perspectives for large-scale repertoire analysis of immune receptors

Systems biology in vaccine design

Th1 response and systemic treg deficiency in inclusion body myositis.

TCR sequences and tissue distribution discriminate the subsets of naïve and activated/memory Treg cells in mice

A profound alteration of blood TCRB repertoire allows prediction of cerebral malaria

Epigenetic regulations in the IFNγ signalling pathway: IFNγ-mediated MHC class I upregulation on tumour cells is associated with DNA demethylation of antigen-presenting machinery genes.

Identification of an endogenous mammary tumor virus involved in the clonal deletion of V beta 2 T cells.

Diversity, molecular characterization and expression of T cell receptor γ in a teleost fish, the sea bass (Dicentrarchus labrax, L).

Clinical-grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene

New methods and software tools for high throughput CDR3 spectratyping. Application to T lymphocyte repertoire modifications during experimental malaria.

Broadened T-cell repertoire diversity in ivIg-treated SLE patients is also related to the individual status of regulatory T-cells

Half of the T-cell repertoire combinatorial diversity is genetically determined in humans and humanized mice.

High-resolution repertoire analysis reveals a major bystander activation of Tfh and Tfr cells

Mechanisms of the natural reactivity of lymphocytes from noninfected individuals to membrane-associated Leishmania infantum antigens

State-transition diagrams for biologists

Contrasted TCRβ diversity of CD8+ and CD8- T cells in rainbow trout

Endogenous TCR recombination in TCR Tg single RAG-deficient mice uncovered by robust in vivo T cell activation and selection

TCR repertoire dynamics in the pancreatic lymph nodes of non-obese diabetic (NOD) mice at the time of disease initiation

Serum biomarker signature identifies patients with B-cell non-Hodgkin lymphoma associated with cryoglobulinemia vasculitis in chronic HCV infection

A novel strategy for molecular signature discovery based on independent component analysis.

Dynamical and Mechanistic Reconstructive Approaches of T Lymphocyte Dynamics: Using Visual Modeling Languages to Bridge the Gap between Immunologists, Theoreticians, and Programmers

A unique CD8(+) T lymphocyte signature in pediatric type 1 diabetes.

Cutting edge: CD4-independent development of functional FoxP3+ regulatory T cells.

Immunomonitoring

Germline genomic structure of the B10.A mouse Tcra-V2 gene subfamily

GeVaDSs - decision support system for novel Genetic Vaccine development process

A conserved sequence in the mouse variable T cell receptor alpha recombination signal sequence 23-bp spacer can affect recombination.

Vaccinomics

A TCRβ Repertoire Signature Can Predict Experimental Cerebral Malaria