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List of works by Mieke Dewerchin

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis

scholarly article

A key role for transketolase-like 1 in tumor metabolic reprogramming

scientific article published on 06 July 2016

A transgenic Xenopus laevis reporter model to study lymphangiogenesis

scientific article

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

scientific article published on 01 March 2020

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

scientific article published on 01 January 2020

Angiogenesis Revisited: An Overlooked Role of Endothelial Cell Metabolism in Vessel Sprouting

scientific article published on 06 August 2015

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

scientific article

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

scientific article

BIOMEX: an interactive workflow for (single cell) omics data interpretation and visualization

scientific article published on 11 May 2020

Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha

scientific journal article

Central Role of Metabolism in Endothelial Cell Function and Vascular Disease

scientific article published on March 2017

Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development

scientific journal article

De novo design of a biologically active amyloid. ⬇️

scientific article

Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism

scientific article published on 06 January 2016

EndoDB: a database of endothelial cell transcriptomics data

scientific article

Erratum: Corrigendum: Fatty acid carbon is essential for dNTP synthesis in endothelial cells

scientific article published in Nature

FAF1, a gene that is disrupted in cleft palate and has conserved function in zebrafish

scientific article

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

scientific article published on April 2015

Gender-specific modulation of the response to arterial injury by soluble guanylate cyclase α1.

scientific article published on 31 August 2009

Glycolytic regulation of cell rearrangement in angiogenesis.

scientific article

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF

scientific article

Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism

scientific article published on 2 January 2014

Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata

scientific journal article

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation

scientific article published on 23 August 2018

Incomplete and transitory decrease of glycolysis: a new paradigm for anti-angiogenic therapy?

scientific article published on 13 December 2013

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy.

scientific article published on 8 November 2016

Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties

scientific article

Inhibition of vascular endothelial growth factor reduces scar formation after glaucoma filtration surgery

scientific article

Liprin (beta)1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity

scientific article

Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

scientific journal article

Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons

scientific journal article

Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration

scientific journal article

Loss or inhibition of stromal-derived PlGF prolongs survival of mice with imatinib-resistant Bcr-Abl1(+) leukemia

scientific article published on June 2011

Lymphatics help baby take first breath

scientific article

Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells.

scientific article

Meta-analysis of clinical metabolic profiling studies in cancer: challenges and opportunities

scientific article published on 06 September 2016

Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis

scientific article published on 12 December 2013

PlGF: a multitasking cytokine with disease-restricted activity

scientific article published on August 2012

Placental growth factor in cancer

scientific article

Principles of targeting endothelial cell metabolism to treat angiogenesis and endothelial cell dysfunction in disease

scientific article

Protocols for endothelial cell isolation from mouse tissues: brain, choroid, lung, and muscle

scientific article published on 14 September 2021

Protocols for endothelial cell isolation from mouse tissues: kidney, spleen, and testis

scientific article published on 28 July 2021

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis ⬇️

scientific article published on 23 August 2018

Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis

scientific article published on 08 February 2016

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

scientific article

Role and therapeutic potential of dietary ketone bodies in lymph vessel growth

scientific article published on 12 July 2019

Role of PFKFB3-driven glycolysis in vessel sprouting

scientific article

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

scientific article

Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles.

scientific article

Role of glutamine and interlinked asparagine metabolism in vessel formation ⬇️

scientific article published on 28 June 2017

Role of glutamine synthetase in angiogenesis beyond glutamine synthesis ⬇️

scientific article published in Nature

Role of synectin in lymphatic development in zebrafish and frogs

scientific article published on 14 July 2010

Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells

article

Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis

scientific article published on 01 April 2020

Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation

scientific article published on 09 December 2019

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

scientific article published on 13 February 2020

Targeted disruption of the murine Plag1 proto-oncogene causes growth retardation and reduced fertility

scientific journal article

The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts

scientific article published on 28 July 2015

The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A

scientific article published on 8 March 2016

The nuclear scaffold protein NIPP1 is essential for early embryonic development and cell proliferation

scientific journal article

The role of fatty acid β-oxidation in lymphangiogenesis

scientific article published on 26 December 2016

Tumor vessel normalization by chloroquine independent of autophagy.

scientific article published on August 2014

VEGF modulates NMDA receptors activity in cerebellar granule cells through Src-family kinases before synapse formation

scientific article

Vascular endothelial growth factor: a neurovascular target in neurological diseases

scientific article published on July 2016

uPA deficiency exacerbates muscular dystrophy in MDX mice

scientific article

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