List of works - Benoît Stijlemans

1,25-Dihydroxyvitamin D3 curtails the inflammatory and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanism

article

A Glycosylphosphatidylinositol-Based Treatment Alleviates Trypanosomiasis-Associated Immunopathology

A New Family of Diverse Skin Peptides from the Microhylid Frog Genus Phrynomantis

scientific article published on 18 February 2020

A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity

scientific article

A conserved flagellar pocket exposed high mannose moiety is used by African trypanosomes as a host cytokine binding molecule.

scientific article published on 12 June 2001

Affinity is an important determinant of the anti-trypanosome activity of nanobodies

scientific article

African Trypanosomes Undermine Humoral Responses and Vaccine Development: Link with Inflammatory Responses?

scientific article published on 24 May 2017

African Trypanosomiasis as Paradigm for Involvement of the Mononuclear Phagocyte System in Pathogenicity During Parasite Infection

African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System

scientific article published on 15 February 2018

African trypanosomosis: from immune escape and immunopathology to immune intervention

scientific article published on 7 June 2007

An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase

scientific article published on 2 February 2016

Antibacterial activities of coagulase-negative staphylococci from bovine teat apex skin and their inhibitory effect on mastitis-related pathogens.

scientific article published on 8 February 2014

Antibody-mediated control of Trypanosoma vivax infection fails in the absence of tumour necrosis factor

scientific article published on June 2014

Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH

scientific article published on 01 July 2005

Attenuation of Trypanosoma brucei is associated with reduced immunosuppression and concomitant production of Th2 lymphokines

scientific article

Bacterial lipoprotein-based vaccines induce tumor necrosis factor-dependent type 1 protective immunity against Leishmania major

scientific article

Camelid immunoglobulins and nanobody technology.

scientific article published on 17 October 2008

Comparative analysis of antibody responses against HSP60, invariant surface glycoprotein 70, and variant surface glycoprotein reveals a complex antigen-specific pattern of immunoglobulin isotype switching during infection by Trypanosoma brucei

scientific article

Control of experimental Trypanosoma brucei infections occurs independently of lymphotoxin-alpha induction

scientific article

Correction: Affinity Is an Important Determinant of the Anti-Trypanosome Activity of Nanobodies.

scientific article

Current status of vaccination against African trypanosomiasis.

scientific article published on 05 May 2010

Detection of clinically relevant antibodies pretransplant and posttransplant with PRA-STAT

scientific article published on 01 February 1997

Development of a pHrodo-based assay for the assessment of in vitro and in vivo erythrophagocytosis during experimental trypanosomosis

scientific article

Differentiation, activation and function of CD11b+Ly6C+ TNF/iNOS-producing dendritic cells during parasitic infection

scholarly article by Tom Bosschaerts et al published October 2009 in Cytokine

Distinct carbohydrate recognition domains of an invertebrate defense molecule recognize Gram-negative and Gram-positive bacteria

scientific article published on 03 October 2001

E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo

scientific article published on 31 July 2015

Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm

scientific article

Evidence for proteins involved in prophenoloxidase cascade Eisenia fetida earthworms

article

Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor

scientific article

Expression and extracellular release of a functional anti-trypanosome Nanobody® in Sodalis glossinidius, a bacterial symbiont of the tsetse fly

scientific article

Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes

scientific article

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection

scientific article published on 03 February 2020

High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis

scientific article

IL-10 limits production of pathogenic TNF by M1 myeloid cells through induction of nuclear NF-κB p50 member in Trypanosoma congolense infection-resistant C57BL/6 mice

scientific article published on 19 September 2011

Identification of a parasitic immunomodulatory protein triggering the development of suppressive M1 macrophages during African trypanosomiasis

scientific article published in December 2009

Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity

scientific article

Inhibition of Staphylococcus epidermidis biofilm formation by rabbit polyclonal antibodies against the SesC protein

scientific article published on 15 June 2009

Iron Homeostasis and Trypanosoma brucei Associated Immunopathogenicity Development: A Battle/Quest for Iron

scientific article published on 18 May 2015

Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice

scientific article

Low structural variation in the host-defense peptide repertoire of the dwarf clawed frog Hymenochirus boettgeri (Pipidae)

scientific article (publication date: 2014)

M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment.

scientific article published on 16 November 2015

MIF contributes to Trypanosoma brucei associated immunopathogenicity development

scientific article

MIF inhibition interferes with the inflammatory and T cell-stimulatory capacity of NOD macrophages and delays autoimmune diabetes onset.

scientific article published on 2 November 2017

MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis

scientific article

Macrophage dynamics are regulated by local macrophage proliferation and monocyte recruitment in injured pancreas.

scientific article published on 19 March 2015

Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis.

scientific article published on 23 June 2016

Monitoring liver macrophages using nanobodies targeting Vsig4: Concanavalin A induced acute hepatitis as paradigm

scientific article published on 02 October 2014

NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia

scientific article published on 12 June 2015

Nanobodies As Tools to Understand, Diagnose, and Treat African Trypanosomiasis

scientific article

Neutrophils enhance early Trypanosoma brucei infection onset

scientific article published in Scientific Reports

Novel half-life extended anti-MIF nanobodies protect against endotoxic shock.

scientific article published on 25 January 2018

Origin and functional diversification of an amphibian defense peptide arsenal

scientific article

Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens

scientific article

Presence and regulation of insulin-regulated aminopeptidase in mouse macrophages.

scientific article published on 14 February 2014

Reprint of: The non-mammalian MIF superfamily

scientific article

Scrutinizing the mechanisms underlying the induction of anemia of inflammation through GPI-mediated modulation of macrophage activation in a model of African trypanosomiasis.

scientific article published in March 2010

Similar inflammatory DC maturation signatures induced by TNF or Trypanosoma brucei antigens instruct default Th2-cell responses

article

The Induction of a Type 1 Immune Response following a Trypanosoma brucei Infection Is MyD88 Dependent

article

The Possible Role of Staphylococcus epidermidis LPxTG Surface Protein SesC in Biofilm Formation.

scientific article published on 22 January 2016

The Road to Personalized Myeloma Medicine: Patient-specific Single-domain Antibodies for Anti-idiotypic Radionuclide Therapy

scientific article published in January 2022

The glycosyl-inositol-phosphate and dimyristoylglycerol moieties of the glycosylphosphatidylinositol anchor of the trypanosome variant-specific surface glycoprotein are distinct macrophage-activating factors ⬇️

scientific article published on February 15, 1998

The non-mammalian MIF superfamily.

scientific article

Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling

scientific article

Tsetse fly saliva accelerates the onset of Trypanosoma brucei infection in a mouse model associated with a reduced host inflammatory response

scientific article

Tsetse salivary gland proteins 1 and 2 are high affinity nucleic acid binding proteins with residual nuclease activity

scientific article

Understanding the role of monocytic cells in liver inflammation using parasite infection as a model

scientific article published on 03 July 2009

Using microdialysis to analyse the passage of monovalent nanobodies through the blood-brain barrier

scientific article published on April 2012

VSG-GPI anchors of African trypanosomes: their role in macrophage activation and induction of infection-associated immunopathology

scientific article published in July 2002

Vaccination with SesC decreases Staphylococcus epidermidis biofilm formation

scientific article

List of works by Benoît Stijlemans

1,25-Dihydroxyvitamin D3 curtails the inflammatory and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanism

A Glycosylphosphatidylinositol-Based Treatment Alleviates Trypanosomiasis-Associated Immunopathology

A New Family of Diverse Skin Peptides from the Microhylid Frog Genus Phrynomantis

A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity

A conserved flagellar pocket exposed high mannose moiety is used by African trypanosomes as a host cytokine binding molecule.

Affinity is an important determinant of the anti-trypanosome activity of nanobodies

African Trypanosomes Undermine Humoral Responses and Vaccine Development: Link with Inflammatory Responses?

African Trypanosomiasis as Paradigm for Involvement of the Mononuclear Phagocyte System in Pathogenicity During Parasite Infection

African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System

African trypanosomosis: from immune escape and immunopathology to immune intervention

An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase

Antibacterial activities of coagulase-negative staphylococci from bovine teat apex skin and their inhibitory effect on mastitis-related pathogens.

Antibody-mediated control of Trypanosoma vivax infection fails in the absence of tumour necrosis factor

Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH

Attenuation of Trypanosoma brucei is associated with reduced immunosuppression and concomitant production of Th2 lymphokines

Bacterial lipoprotein-based vaccines induce tumor necrosis factor-dependent type 1 protective immunity against Leishmania major

Camelid immunoglobulins and nanobody technology.

Comparative analysis of antibody responses against HSP60, invariant surface glycoprotein 70, and variant surface glycoprotein reveals a complex antigen-specific pattern of immunoglobulin isotype switching during infection by Trypanosoma brucei

Control of experimental Trypanosoma brucei infections occurs independently of lymphotoxin-alpha induction

Correction: Affinity Is an Important Determinant of the Anti-Trypanosome Activity of Nanobodies.

Current status of vaccination against African trypanosomiasis.

Detection of clinically relevant antibodies pretransplant and posttransplant with PRA-STAT

Development of a pHrodo-based assay for the assessment of in vitro and in vivo erythrophagocytosis during experimental trypanosomosis

Differentiation, activation and function of CD11b+Ly6C+ TNF/iNOS-producing dendritic cells during parasitic infection

Distinct carbohydrate recognition domains of an invertebrate defense molecule recognize Gram-negative and Gram-positive bacteria

E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo

Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm

Evidence for proteins involved in prophenoloxidase cascade Eisenia fetida earthworms

Experimental therapy of African trypanosomiasis with a nanobody-conjugated human trypanolytic factor

Expression and extracellular release of a functional anti-trypanosome Nanobody® in Sodalis glossinidius, a bacterial symbiont of the tsetse fly

Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection

High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis

IL-10 limits production of pathogenic TNF by M1 myeloid cells through induction of nuclear NF-κB p50 member in Trypanosoma congolense infection-resistant C57BL/6 mice

Identification of a parasitic immunomodulatory protein triggering the development of suppressive M1 macrophages during African trypanosomiasis

Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity

Inhibition of Staphylococcus epidermidis biofilm formation by rabbit polyclonal antibodies against the SesC protein

Iron Homeostasis and Trypanosoma brucei Associated Immunopathogenicity Development: A Battle/Quest for Iron

Liver X receptors contribute to the protective immune response against Mycobacterium tuberculosis in mice

Low structural variation in the host-defense peptide repertoire of the dwarf clawed frog Hymenochirus boettgeri (Pipidae)

M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment.

MIF contributes to Trypanosoma brucei associated immunopathogenicity development

MIF inhibition interferes with the inflammatory and T cell-stimulatory capacity of NOD macrophages and delays autoimmune diabetes onset.

MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis

Macrophage dynamics are regulated by local macrophage proliferation and monocyte recruitment in injured pancreas.

Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis.

Monitoring liver macrophages using nanobodies targeting Vsig4: Concanavalin A induced acute hepatitis as paradigm

NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia

Nanobodies As Tools to Understand, Diagnose, and Treat African Trypanosomiasis

Neutrophils enhance early Trypanosoma brucei infection onset

Novel half-life extended anti-MIF nanobodies protect against endotoxic shock.

Origin and functional diversification of an amphibian defense peptide arsenal

Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens

Presence and regulation of insulin-regulated aminopeptidase in mouse macrophages.

Reprint of: The non-mammalian MIF superfamily

Scrutinizing the mechanisms underlying the induction of anemia of inflammation through GPI-mediated modulation of macrophage activation in a model of African trypanosomiasis.

Similar inflammatory DC maturation signatures induced by TNF or Trypanosoma brucei antigens instruct default Th2-cell responses

The Induction of a Type 1 Immune Response following a Trypanosoma brucei Infection Is MyD88 Dependent

The Possible Role of Staphylococcus epidermidis LPxTG Surface Protein SesC in Biofilm Formation.

The Road to Personalized Myeloma Medicine: Patient-specific Single-domain Antibodies for Anti-idiotypic Radionuclide Therapy

The glycosyl-inositol-phosphate and dimyristoylglycerol moieties of the glycosylphosphatidylinositol anchor of the trypanosome variant-specific surface glycoprotein are distinct macrophage-activating factors ⬇️

The non-mammalian MIF superfamily.

Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling

Tsetse fly saliva accelerates the onset of Trypanosoma brucei infection in a mouse model associated with a reduced host inflammatory response

Tsetse salivary gland proteins 1 and 2 are high affinity nucleic acid binding proteins with residual nuclease activity

Understanding the role of monocytic cells in liver inflammation using parasite infection as a model

Using microdialysis to analyse the passage of monovalent nanobodies through the blood-brain barrier

VSG-GPI anchors of African trypanosomes: their role in macrophage activation and induction of infection-associated immunopathology

Vaccination with SesC decreases Staphylococcus epidermidis biofilm formation