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List of works by Jaap Keijer

A Difference in Fatty Acid Composition of Isocaloric High-Fat Diets Alters Metabolic Flexibility in Male C57BL/6JOlaHsd Mice.

scientific article published on 22 June 2015

A Lowly Digestible-Starch Diet after Weaning Enhances Exogenous Glucose Oxidation Rate in Female, but Not in Male, Mice

scientific article published on 18 September 2019

Adaptation of exercise-induced stress in well-trained healthy young men.

scientific article published on 3 November 2016

Adipose gene expression response of lean and obese mice to short-term dietary restriction.

scientific article published in June 2006

Adipose tissue failure and mitochondria as a possible target for improvement by bioactive food components

scientific article published on February 2008

Adipose tissue metabolism and inflammation are differently affected by weight loss in obese mice due to either a high-fat diet restriction or change to a low-fat diet

scientific article

Alterations in hepatic one-carbon metabolism and related pathways following a high-fat dietary intervention

scientific article (publication date: 8 February 2011)

An optimized desuccinylase activity assay reveals a difference in desuccinylation activity between proliferative and differentiated cells

scientific article published on 12 October 2020

Angiogenesis in Balb/c mice under beta-carotene supplementation in diet

scientific article

Assessment of metabolic flexibility of old and adult mice using three noninvasive, indirect calorimetry-based treatments.

scientific article published on 10 March 2014

Assessment of reducing RNA input for Agilent oligo microarrays

scientific article published on 18 January 2007

Assessment of representational difference analysis (RDA) to construct informative cDNA microarrays for gene expression analysis of species with limited transcriptome information, using red and green tomatoes as a model

scientific article published on 21 April 2006

BIOCLAIMS standard diet (BIOsd): a reference diet for nutritional physiology

scientific article

Beta-carotene affects gene expression in lungs of male and female Bcmo1 (-/-) mice in opposite directions

scientific article

Beta-carotene affects oxidative stress-related DNA damage in lung epithelial cells and in ferret lung

scientific article published in December 2009

Beta-carotene and the application of transcriptomics in risk-benefit evaluation of natural dietary components.

scientific article

Beta-carotene reduces body adiposity of mice via BCMO1

scientific article

Bioactive food components, cancer cell growth limitation and reversal of glycolytic metabolism.

scientific article published on 21 August 2010

Blood cells transcriptomics as source of potential biomarkers of articular health improvement: effects of oral intake of a rooster combs extract rich in hyaluronic acid

scientific article

Body Weight Cycling with Identical Diet Composition Does Not Affect Energy Balance and Has No Adverse Effect on Metabolic Health Parameters.

scientific article

Carboxypeptidase E and thrombospondin-1 are differently expressed in subcutaneous and visceral fat of obese subjects.

scientific article

Combined Treatment with L-Carnitine and Nicotinamide Riboside Improves Hepatic Metabolism and Attenuates Obesity and Liver Steatosis

scientific article published on 05 September 2019

Comparative expression analysis of isolated human adipocytes and the human adipose cell lines LiSa-2 and PAZ6.

scientific article

Complex regulation of mucosal pentraxin (Mptx) revealed by discrete micro-anatomical locations in colon

scientific article published on 15 August 2006

Deconjugation kinetics of glucuronidated phase II flavonoid metabolites by beta-glucuronidase from neutrophils.

scientific article published on January 2010

Development of a rapid yeast estrogen bioassay, based on the expression of green fluorescent protein.

scientific article published in January 2004

Diet-Independent Correlations between Bacteria and Dysfunction of Gut, Adipose Tissue, and Liver: A Comprehensive Microbiota Analysis in Feces and Mucosa of the Ileum and Colon in Obese Mice with NAFLD ⬇️

scientific article published on 20 December 2018

Dietary folate intake in combination with MTHFR C677T genotype and promoter methylation of tumor suppressor and DNA repair genes in sporadic colorectal adenomas

scientific article published on 01 February 2007

Dietary modulation and structure prediction of rat mucosal pentraxin (Mptx) protein and loss of function in humans

scientific article

Differential gene expression in rat colon by dietary heme and calcium.

scientific article published on 11 November 2004

Direct and Long-Term Metabolic Consequences of Lowly vs. Highly-Digestible Starch in the Early Post-Weaning Diet of Mice

scientific article published on 17 November 2018

Direct comparison of metabolic health effects of the flavonoids quercetin, hesperetin, epicatechin, apigenin and anthocyanins in high-fat-diet-fed mice

scientific article published on 29 May 2015

Dynamic changes in energy metabolism upon embryonic stem cell differentiation support developmental toxicant identification.

scientific article

Early differences in metabolic flexibility between obesity-resistant and obesity-prone mice

scientific article published on 19 November 2015

Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet.

scientific article published on 16 February 2017

Effects of chocolate supplementation on metabolic and cardiovascular parameters in ApoE3L mice fed a high-cholesterol atherogenic diet.

scientific article published on 15 August 2013

Effects of cold exposure revealed by global transcriptomic analysis in ferret peripheral blood mononuclear cells

scientific article published on 27 December 2019

Effects of dietary history on energy metabolism and physiological parameters in C57BL/6J mice

scientific article published on 13 December 2012

Endurance Exercise Increases Intestinal Uptake of the Peanut Allergen Ara h 6 after Peanut Consumption in Humans

scientific article published on 21 January 2017

Factors influencing cDNA microarray hybridization on silylated glass slides

scientific article published on 01 September 2002

Follicular development of sows at weaning in relation to estimated breeding value for within-litter variation in piglet birth weight

scientific article published on 09 July 2018

Four selenoproteins, protein biosynthesis, and Wnt signalling are particularly sensitive to limited selenium intake in mouse colon

scientific article (publication date: December 2009)

Functional relationship between obesity and male reproduction: from humans to animal models

scientific article (publication date: 2011)

Gene expression in chicken reveals correlation with structural genomic features and conserved patterns of transcription in the terrestrial vertebrates

scientific article

Gene expression profiling of adipose tissue: individual, depot-dependent, and sex-dependent variabilities

scientific article published on January 2004

Gene expression response of mouse lung, liver and white adipose tissue to β-carotene supplementation, knockout of Bcmo1 and sex.

scientific article published on 19 July 2011

Glycemic index differences of high-fat diets modulate primarily lipid metabolism in murine adipose tissue.

scientific article

High Dose of Dietary Nicotinamide Riboside Induces Glucose Intolerance and White Adipose Tissue Dysfunction in Mice Fed a Mildly Obesogenic Diet

scientific article published on 13 October 2019

High folic acid increases cell turnover and lowers differentiation and iron content in human HT29 colon cancer cells

scientific article published on 10 September 2007

High-resolution genotyping of Salmonella strains by AFLP-fingerprinting.

scientific article published in February 1998

Ileal mucosal and fecal pancreatitis associated protein levels reflect severity of salmonella infection in rats.

scientific article published in December 2009

Impaired barrier function by dietary fructo-oligosaccharides (FOS) in rats is accompanied by increased colonic mitochondrial gene expression

scientific article

Induction of lipid oxidation by polyunsaturated fatty acids of marine origin in small intestine of mice fed a high-fat diet.

scientific article

Induction of peroxisome proliferator-activated receptor γ (PPARγ)-mediated gene expression by tomato (Solanum lycopersicum L.) extracts.

scientific article published on 2 April 2013

Insulin sensitivity linked skeletal muscle Nr4a1 DNA methylation is programmed by the maternal diet and modulated by voluntary exercise in mice

scientific article published on 21 March 2018

Integration of risk and benefit analysis-the window of benefit as a new tool?

scientific article published on August 2009

Interference of flavonoids with enzymatic assays for the determination of free fatty acid and triglyceride levels.

scientific article published on 26 November 2011

Intra- and interindividual variation in gene expression in human adipose tissue.

scientific article published on 24 October 2006

Intramuscular short-chain acylcarnitines in elderly people are decreased in (pre-)frail females, but not in males

scientific article published on 16 July 2020

Isocaloric high-fat feeding directs hepatic metabolism to handling of nutrient imbalance promoting liver fat deposition

scientific article published on 22 March 2016

Knockout of the Bcmo1 gene results in an inflammatory response in female lung, which is suppressed by dietary beta-carotene

scientific article

Krill Oil Treatment Increases Distinct PUFAs and Oxylipins in Adipose Tissue and Liver and Attenuates Obesity-Associated Inflammation via Direct and Indirect Mechanisms

scientific article published in 2021

Marginal selenium deficiency down-regulates inflammation-related genes in splenic leukocytes of the mouse

article

Maternal Circulating Vitamin Status and Colostrum Vitamin Composition in Healthy Lactating Women-A Systematic Approach.

scientific article published on 28 May 2018

Mating type-correlated molecular markers and demonstration of heterokaryosis in the phytopathogenic fungus Thanatephorus cucumeris (Rhizoctonia solani) AG 1-IC by AFLP DNA fingerprinting analysis.

scientific article published on January 1999

Matrisome, innervation and oxidative metabolism affected in older compared with younger males with similar physical activity

scientific article published on 04 July 2021

Metabolic effects of the dietary monosaccharides fructose, fructose-glucose, or glucose in mice fed a starch-containing moderate high-fat diet

scientific article published on 01 February 2020

Mitochondrial (dys)function in adipocyte (de)differentiation and systemic metabolic alterations

scientific article published on 21 August 2009

Mitochondrial dysfunction in primary human fibroblasts triggers an adaptive cell survival program that requires AMPK-α.

scientific article published on 20 December 2014

Mucosal pentraxin (Mptx), a novel rat gene 10-fold down-regulated in colon by dietary heme.

scientific article

Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action

scientific article published on 24 November 2015

Muscle mitohormesis promotes cellular survival via serine/glycine pathway flux.

scientific article published on 9 December 2014

No Adverse Programming by Post-Weaning Dietary Fructose of Body Weight, Adiposity, Glucose Tolerance, or Metabolic Flexibility.

scientific article published on 16 October 2017

Not so hot: Optimal housing temperatures for mice to mimic the thermal environment of humans

scientific article

Not so nuanced: Reply to the comments of Gaskill and Garner on 'Not so hot: Optimal housing temperatures for mice to mimic the environment of humans'.

scientific article

Nutrient-gene interactions in benefit-risk analysis.

scientific article published on June 2006

Nutrigenomic approaches for benefit-risk analysis of foods and food components: defining markers of health

article

Nutrigenomics of body weight regulation: a rationale for careful dissection of individual contributors

scientific article

Nutritional factors and progenitor cell differentiation.

scientific article published on October 2007

Omega-3 Phospholipids from Krill Oil Enhance Intestinal Fatty Acid Oxidation More Effectively than Omega-3 Triacylglycerols in High-Fat Diet-Fed Obese Mice

scientific article published on 09 July 2020

Omega-3 phospholipids from fish suppress hepatic steatosis by integrated inhibition of biosynthetic pathways in dietary obese mice

scientific article published on 01 February 2014

Oxygen restriction as challenge test reveals early high-fat-diet-induced changes in glucose and lipid metabolism

scientific article published in July 2014

Peripheral blood mononuclear cells as a model to study the response of energy homeostasis-related genes to acute changes in feeding conditions.

scientific article published in April 2010

Peripheral blood mononuclear cells as a source to detect markers of homeostatic alterations caused by the intake of diets with an unbalanced macronutrient composition

article

Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce beta-oxidation in white fat.

scientific article published on 5 October 2005

Preservation of metabolic flexibility in skeletal muscle by a combined use of n-3 PUFA and rosiglitazone in dietary obese mice

scientific article (publication date: 2012)

Profiling of the secreted proteins during 3T3-L1 adipocyte differentiation leads to the identification of novel adipokines

scientific journal article

Quercetin decreases high-fat diet induced body weight gain and accumulation of hepatic and circulating lipids in mice.

scientific article

Quercetin induces hepatic lipid omega-oxidation and lowers serum lipid levels in mice

scientific article published on 24 January 2013

Quercetin tests negative for genotoxicity in transcriptome analyses of liver and small intestine of mice.

scientific article published on 8 April 2015

Rapid yeast estrogen bioassays stably expressing human estrogen receptors alpha and beta, and green fluorescent protein: a comparison of different compounds with both receptor types.

scientific article

Reduced fetal androgen exposure compromises Leydig cell function in adulthood

scientific article

Role of Frizzled6 in the molecular mechanism of beta-carotene action in the lung.

scientific article published on 21 March 2014

SIRT1 stimulation by polyphenols is affected by their stability and metabolism.

scientific article published on 17 April 2006

Salmonella induces prominent gene expression in the rat colon

scientific article

Short-term, high fat feeding-induced changes in white adipose tissue gene expression are highly predictive for long-term changes

scientific article

Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine

scientific article published on 17 December 2013

Slc27a2 expression in peripheral blood mononuclear cells as a molecular marker for overweight development

article

Supplemental calcium attenuates the colitis-related increase in diarrhea, intestinal permeability, and extracellular matrix breakdown in HLA-B27 transgenic rats.

scientific article published on 17 June 2009

The MemTrax Test Compared to the Montreal Cognitive Assessment Estimation of Mild Cognitive Impairment

scientific article published on 01 January 2019

The Molecular and Physiological Effects of Protein-Derived Polyamines in the Intestine

scientific article published on 11 January 2020

The application of DNA microarrays in gene expression analysis.

scientific article

The challenges for molecular nutrition research 2: quantification of the nutritional phenotype

scientific article

The chemotactic activity of beta-carotene in endothelial cell progenitors and human umbilical vein endothelial cells: A microarray analysis

scientific article published on January 2006

The circulating PBEF/NAMPT/visfatin level is associated with a beneficial blood lipid profile

scientific article published on 12 April 2007

The effect of endurance exercise on intestinal integrity in well-trained healthy men.

scientific article

The intraclass correlation coefficient applied for evaluation of data correction, labeling methods, and rectal biopsy sampling in DNA microarray experiments

scientific article

The ketogenic diet as a therapeutic intervention strategy in mitochondrial disease

scientific article published in 2021

The secretory function of adipocytes in the physiology of white adipose tissue

scientific article published on July 2008

Thermoneutrality results in prominent diet-induced body weight differences in C57BL/6J mice, not paralleled by diet-induced metabolic differences

scientific article published on 18 November 2013

Transient Hypothyroidism: Dual Effect on Adult-Type Leydig Cell and Sertoli Cell Development

scientific article

Uptake and metabolism of enterolactone and enterodiol by human colon epithelial cells.

scientific article published on March 2005

White adipose tissue reference network: a knowledge resource for exploring health-relevant relations

scientific article

beta-Carotene conversion products and their effects on adipose tissue.

scientific article published on 26 June 2009

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