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List of works by Nathalie Chaput

A novel dendritic cell subset involved in tumor immunosurveillance

scientific article published on 29 January 2006

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

scientific article published on 8 May 2011

An inhibitor of cyclin-dependent kinases suppresses TLR signaling and increases the susceptibility of cancer patients to herpesviridae

scientific article published in January 2011

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

scientific article published on 5 November 2015

Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25.

scientific article

Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab

scientific article published on 27 March 2017

CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner

scientific article

Calreticulin exposure on malignant blasts predicts a cellular anticancer immune response in patients with acute myeloid leukemia

scientific article

Cancer Immunotherapy with Anti-CTLA-4 Monoclonal Antibodies Induces an Inflammatory Bowel Disease

scientific article published on 18 January 2016

Cancer-Induced Immunosuppression: IL-18-Elicited Immunoablative NK Cells

scientific article published on 16 March 2012

Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death

scientific article

Clinical impact of the NKp30/B7-H6 axis in high-risk neuroblastoma patients

scientific article

Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy

scientific article

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

Ctla-4 blockade confers lymphocyte resistance to regulatory T-cells in advanced melanoma: surrogate marker of efficacy of tremelimumab?

scientific article published in August 2008

Dendritic cell derived-exosomes: biology and clinical implementations

scientific article published on 29 June 2006

Dendritic cell maturation overrules H-2D-mediated natural killer T (NKT) cell inhibition: critical role for B7 in CD1d-dependent NKT cell interferon gamma production

scientific article

Dendritic cell-derived exosomes as cell-free peptide-based vaccines

scientific article

Dendritic cell-derived exosomes as immunotherapies in the fight against cancer

scientific article

Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC.

scientific article published on 12 August 2015

Dendritic cell-derived exosomes for cancer immunotherapy: what's next?

scientific article published on 09 February 2010

Dendritic cell-derived exosomes promote natural killer cell activation and proliferation: a role for NKG2D ligands and IL-15Ralpha

scientific article

Dendritic cells and innate defense against tumor cells

scientific article published on 26 December 2007

Ecto-calreticulin in immunogenic chemotherapy

scientific article published on December 2007

Erratum: anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25.

scientific article published in March 2015

Exosome-based immunotherapy

scientific article published on 16 January 2004

Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells

scientific article published on February 2004

Exosomes as potent cell-free peptide-based vaccine. II. Exosomes in CpG adjuvants efficiently prime naive Tc1 lymphocytes leading to tumor rejection

scientific article published on February 2004

Exosomes for immunotherapy of cancer.

scientific article

Exosomes for the treatment of human malignancies

scientific article published on February 2008

Exosomes: immune properties and potential clinical implementations

scientific article published on 21 December 2010

From the antigen-presenting cell to the antigen-presenting vesicle: the exosomes.

scientific article

Hypermutated tumours in the era of immunotherapy: The paradigm of personalised medicine

scientific article published on 24 August 2017

Hyperprogressive Disease Is a New Pattern of Progression in Cancer Patients Treated by Anti-PD-1/PD-L1.

scientific article

IL-15 Trans-Signaling with the Superagonist RLI Promotes Effector/Memory CD8+ T Cell Responses and Enhances Antitumor Activity of PD-1 Antagonists.

scientific article published on 23 May 2016

IL-21-Induced MHC Class II+ NK Cells Promote the Expansion of Human Uncommitted CD4+ Central Memory T Cells in a Macrophage Migration Inhibitory Factor-Dependent Manner.

scientific article published on 27 May 2016

IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules

scientific article published in May 2004

Imatinib mesylate (Gleevec): targeted therapy against cancer with immune properties

scientific article published on March 2010

Immune infiltrates are prognostic factors in localized gastrointestinal stromal tumors

scientific article

Immune response against dying tumor cells

scientific article

Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway

scientific article published on 26 April 2010

Immunomodulatory effects of cyclophosphamide and implementations for vaccine design

scientific article

Inflammatory bowel disease and cancer response due to anti-CTLA-4: is it in the flora?

scientific article published on 16 January 2017

Inflammatory gastrointestinal diseases associated with PD-1 blockade antibodies

scientific article

Integrating Circulating Biomarkers in the Immune Checkpoint Inhibitor Treatment in Lung Cancer

scientific article published on 03 December 2020

Interferon-gamma is produced by another player of innate immune responses: the interferon-producing killer dendritic cell (IKDC).

scientific article published on 5 May 2007

Killer dendritic cells and their potential role in immunotherapy

scientific article published on February 2008

Killer dendritic cells: IKDC and the others

scientific article published on 12 June 2008

Molecular determinants of immunogenic cell death: surface exposure of calreticulin makes the difference

scientific article published on 22 May 2007

Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients

scientific article

Natural killer cell-directed therapies: moving from unexpected results to successful strategies

scientific article published on May 2008

Natural killer cells in non-hematopoietic malignancies

scientific article

Opposing effects of toll-like receptor (TLR3) signaling in tumors can be therapeutically uncoupled to optimize the anticancer efficacy of TLR3 ligands

scientific article

Phase I clinical trial combining imatinib mesylate and IL-2 in refractory cancer patients: IL-2 interferes with the pharmacokinetics of imatinib mesylate

scientific article published on February 2013

Phase I clinical trial combining imatinib mesylate and IL-2: HLA-DR(+) NK cell levels correlate with disease outcome

scientific article published on February 2013

Potent immunomodulatory effects of the trifunctional antibody catumaxomab

scientific article published on 4 June 2013

Predictive biomarkers for programmed death-1/programmed death ligand immune checkpoint inhibitors in nonsmall cell lung cancer

scientific article

Prognostic value of HLA-A2 status in advanced non-small cell lung cancer patients

scientific article published on 29 July 2017

Regulation of CD4(+)NKG2D(+) Th1 cells in patients with metastatic melanoma treated with sorafenib: role of IL-15Rα and NKG2D triggering

scientific article published on 6 November 2013

Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer

scientific article published on 01 May 2020

The Janus face of dendritic cells in cancer

scientific article published on October 2008

The critical role of IL-15 in the antitumor effects mediated by the combination therapy imatinib and IL-2.

scientific article published in May 2008

The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells

scientific article published in August 2009

The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy

scientific article published on December 2007

The potential of exosomes in immunotherapy

scientific article

The potential of exosomes in immunotherapy of cancer

scientific article

Therapy-induced tumor immunosurveillance involves IFN-producing killer dendritic cells

scientific article published on February 2007

Trans-presentation of IL-15 dictates IFN-producing killer dendritic cells effector functions

scientific article

Treatment of gastric peritoneal carcinomatosis by combining complete surgical resection of lesions and intraperitoneal immunotherapy using catumaxomab

scientific article

Tumour-infiltrating CD68+ and CD57+ cells predict patient outcome in stage II-III colorectal cancer

scientific article published on 18 July 2013

Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial

scientific article

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