List of works - Ivan Bièche

A Molecular Predictor Reassesses Classification of Human Grade II/III Gliomas

scientific article

A quantitative gene expression study suggests a role for angiopoietins in focal nodular hyperplasia

scientific article (publication date: March 2003)

An entire exon 3 germ-line rearrangement in the BRCA2 gene: pathogenic relevance of exon 3 deletion in breast cancer predisposition

scientific article

Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile

scientific article

Arpin downregulation in breast cancer is associated with poor prognosis

scientific article

CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors

scientific article

Changes in autophagic response in patients with chronic hepatitis C virus infection

scientific article

Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF.

scientific article

Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut.

scientific article

Control of MT1-MMP transport by atypical PKC during breast-cancer progression

scientific article

Differential distribution of erbB receptors in human glioblastoma multiforme: expression of erbB3 in CD133-positive putative cancer stem cells

scientific article

Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data

scientific article published on 24 February 2015

Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy

scientific article

Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway

scientific article

Genetics, genomics, and proteomics: implications for the diagnosis and the treatment of chronic hepatitis C.

scientific article published on February 2007

IFI35, mir-99a and HCV genotype to predict sustained virological response to pegylated-interferon plus ribavirin in chronic hepatitis C.

scientific article

Identification of a three-gene expression signature of poor-prognosis breast carcinoma

scientific article

Identification of new candidate therapeutic target genes in triple-negative breast cancer

scientific article

Identification of novel gene expression targets for the Ras association domain family 1 (RASSF1A) tumor suppressor gene in non-small cell lung cancer and neuroblastoma

scientific article

Increased VEGFR2 expression during human late endothelial progenitor cells expansion enhances in vitro angiogenesis with up-regulation of integrin alpha(6)

scientific article

Inhibiting aurora kinases reduces tumor growth and suppresses tumor recurrence after chemotherapy in patient-derived triple-negative breast cancer xenografts

scientific article

Inhibitory signalling to the Arp2/3 complex steers cell migration

scientific article

Molecular profiling of hepatocellular carcinomas (HCC) using a large-scale real-time RT-PCR approach: determination of a molecular diagnostic index

scientific article published on August 2003

Molecular profiling of malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1, based on large-scale real-time RT-PCR

scientific article

Mutational analysis of anal cancers demonstrates frequent PIK3CA mutations associated with poor outcome after salvage abdominoperineal resection

scientific article published on 24 May 2016

NF1 microdeletions in neurofibromatosis type 1: from genotype to phenotype

scientific article

PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups

scientific article

PIK3R1 underexpression is an independent prognostic marker in breast cancer

scientific article

Predictive gene signature of response to the anti-TweakR mAb PDL192 in patient-derived breast cancer xenografts

scientific article

Protein kinase D1 regulates ERα-positive breast cancer cell growth response to 17β-estradiol and contributes to poor prognosis in patients

scientific article

Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human

scientific article

Relationship between intratumoral expression of genes coding for xenobiotic-metabolizing enzymes and benefit from adjuvant tamoxifen in estrogen receptor alpha-positive postmenopausal breast carcinoma

scientific article

Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues

scientific article

Role of WISP-2/CCN5 in the maintenance of a differentiated and noninvasive phenotype in human breast cancer cells

scientific article

Role of estrogen receptor alpha transcriptional coregulators in tamoxifen resistance in breast cancer

scientific article published on 5 July 2006

SISH/CISH or qPCR as alternative techniques to FISH for determination of HER2 amplification status on breast tumors core needle biopsies: a multicenter experience based on 840 cases

scientific article

Significant gene expression differences in histologically "Normal" liver biopsies: Implications for control tissue

scientific article

The Tumor-Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the β-Catenin Coactivator BCL9-2 in Breast Cancer Cells

scientific article

The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

scientific article

Thrombin bound to a fibrin clot confers angiogenic and haemostatic properties on endothelial progenitor cells

scientific article

Thrombospondin-1 is a plasmatic marker of peripheral arterial disease that modulates endothelial progenitor cell angiogenic properties

scientific article

Treatment Algorithms Based on Tumor Molecular Profiling: The Essence of Precision Medicine Trials

scientific article

List of works by Ivan Bièche

A Molecular Predictor Reassesses Classification of Human Grade II/III Gliomas

A quantitative gene expression study suggests a role for angiopoietins in focal nodular hyperplasia

An entire exon 3 germ-line rearrangement in the BRCA2 gene: pathogenic relevance of exon 3 deletion in breast cancer predisposition

Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile

Arpin downregulation in breast cancer is associated with poor prognosis

CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors

Changes in autophagic response in patients with chronic hepatitis C virus infection

Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF.

Concomitant Notch activation and p53 deletion trigger epithelial-to-mesenchymal transition and metastasis in mouse gut.

Control of MT1-MMP transport by atypical PKC during breast-cancer progression

Differential distribution of erbB receptors in human glioblastoma multiforme: expression of erbB3 in CD133-positive putative cancer stem cells

Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data

Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy

Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway

Genetics, genomics, and proteomics: implications for the diagnosis and the treatment of chronic hepatitis C.

IFI35, mir-99a and HCV genotype to predict sustained virological response to pegylated-interferon plus ribavirin in chronic hepatitis C.

Identification of a three-gene expression signature of poor-prognosis breast carcinoma

Identification of new candidate therapeutic target genes in triple-negative breast cancer

Identification of novel gene expression targets for the Ras association domain family 1 (RASSF1A) tumor suppressor gene in non-small cell lung cancer and neuroblastoma

Increased VEGFR2 expression during human late endothelial progenitor cells expansion enhances in vitro angiogenesis with up-regulation of integrin alpha(6)

Inhibiting aurora kinases reduces tumor growth and suppresses tumor recurrence after chemotherapy in patient-derived triple-negative breast cancer xenografts

Inhibitory signalling to the Arp2/3 complex steers cell migration

Molecular profiling of hepatocellular carcinomas (HCC) using a large-scale real-time RT-PCR approach: determination of a molecular diagnostic index

Molecular profiling of malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1, based on large-scale real-time RT-PCR

Mutational analysis of anal cancers demonstrates frequent PIK3CA mutations associated with poor outcome after salvage abdominoperineal resection

NF1 microdeletions in neurofibromatosis type 1: from genotype to phenotype

PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups

PIK3R1 underexpression is an independent prognostic marker in breast cancer

Predictive gene signature of response to the anti-TweakR mAb PDL192 in patient-derived breast cancer xenografts

Protein kinase D1 regulates ERα-positive breast cancer cell growth response to 17β-estradiol and contributes to poor prognosis in patients

Quantitative RT-PCR reveals a ubiquitous but preferentially neural expression of the KIS gene in rat and human

Relationship between intratumoral expression of genes coding for xenobiotic-metabolizing enzymes and benefit from adjuvant tamoxifen in estrogen receptor alpha-positive postmenopausal breast carcinoma

Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues

Role of WISP-2/CCN5 in the maintenance of a differentiated and noninvasive phenotype in human breast cancer cells

Role of estrogen receptor alpha transcriptional coregulators in tamoxifen resistance in breast cancer

SISH/CISH or qPCR as alternative techniques to FISH for determination of HER2 amplification status on breast tumors core needle biopsies: a multicenter experience based on 840 cases

Significant gene expression differences in histologically "Normal" liver biopsies: Implications for control tissue

The Tumor-Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the β-Catenin Coactivator BCL9-2 in Breast Cancer Cells

The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

Thrombin bound to a fibrin clot confers angiogenic and haemostatic properties on endothelial progenitor cells

Thrombospondin-1 is a plasmatic marker of peripheral arterial disease that modulates endothelial progenitor cell angiogenic properties

Treatment Algorithms Based on Tumor Molecular Profiling: The Essence of Precision Medicine Trials