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List of works by Dieter Flesch-Janys

11q13 is a susceptibility locus for hormone receptor positive breast cancer

scientific article

19p13.1 is a triple-negative-specific breast cancer susceptibility locus

scientific article published on 13 February 2012

2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy

scientific article

7q21-rs6964587 and breast cancer risk: an extended case-control study by the Breast Cancer Association Consortium

scientific article

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium

scientific article published on 02 August 2012

A Comprehensive Multistate Model Analyzing Associations of Various Risk Factors With the Course of Breast Cancer in a Population-Based Cohort of Breast Cancer Cases

scientific article published on 27 January 2016

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer

scientific article published on 30 October 2011

A genome-wide "pleiotropy scan" does not identify new susceptibility loci for estrogen receptor negative breast cancer

scientific article

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.

scientific article

A genome-wide association study to identify genetic susceptibility loci that modify ductal and lobular postmenopausal breast cancer risk associated with menopausal hormone therapy use: a two-stage design with replication

scientific article published on 20 February 2013

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium

scientific article

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

scientific article

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.

scientific article

A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients

scientific article published on 16 December 2015

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

scientific article published on 18 June 2018

Anti-nuclear autoantibodies in the general German population: prevalence and lack of association with selected cardiovascular and metabolic disorders-findings of a multicenter population-based study

scientific article

Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study

scientific article

Association analysis identifies 65 new breast cancer risk loci.

scientific article published on 23 October 2017

Association of ESR1 gene tagging SNPs with breast cancer risk

scientific article published on 06 January 2009

Association of a common AKAP9 variant with breast cancer risk: a collaborative analysis

scientific article published on 11 March 2008

Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry

scientific article published on 06 April 2016

Association of pre-diagnosis physical activity with recurrence and mortality among women with breast cancer

scientific article published on 18 March 2013

Associations between adjuvant radiotherapy and different causes of death in a German breast cancer cohort

scientific article published on 14 December 2017

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

scientific article

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

scientific article

Body mass index and breast cancer survival: a Mendelian randomization analysis

scientific article published in December 2017

Cancer mortality among workers in chemical plant contaminated with dioxin ⬇️

scientific article published on October 19, 1991

Cancer mortality in German male workers exposed to phenoxy herbicides and dioxins

scientific article published on 01 May 1996

Cancer mortality in workers exposed to phenoxy herbicides, chlorophenols, and dioxins: an expanded and updated international cohort study

journal article published in 1997

Cancer risk factors associated with insulin-like growth factor (IGF)-I and IGF-binding protein-3 levels in healthy women: effect modification by menopausal status.

scientific article published in December 2009

Circulating 25-hydroxyvitamin D and postmenopausal breast cancer survival: Influence of tumor characteristics and lifestyle factors?

scientific article

Coffee consumption modifies risk of estrogen-receptor negative breast cancer

scientific article published on 14 May 2011

Collection of vaccination data in the German National Cohort : Findings of a feasibility study in three study centers

scientific article

Common breast cancer susceptibility loci are associated with triple-negative breast cancer

scientific article published on 15 August 2011

Common germline polymorphisms associated with breast cancer-specific survival

scientific article published on 22 April 2015

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium

scientific article

Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

scientific article

Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer

scientific article

Confirmation of the reduction of hormone replacement therapy-related breast cancer risk for carriers of the HSD17B1_937_G variant

scientific article

Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

scientific article published in PLoS ONE

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

scientific article

Deregulated Serum Concentrations of Circulating Cell–Free MicroRNAs miR-17, miR-34a, miR-155, and miR-373 in Human Breast Cancer Development and Progression ⬇️

scientific article published on June 7, 2013

Determinants of long-term fatigue in breast cancer survivors: results of a prospective patient cohort study

scientific article published on 17 May 2014

Determinants of newly diagnosed comorbidities among breast cancer survivors

scientific article published on 26 February 2014

Determinants of sports, cycling, walking and overall leisure-time physical activity among postmenopausal women in Germany

scientific article published on 13 July 2010

Determination of nasal and oropharyngeal microbiomes in a multicenter population-based study - findings from Pretest 1 of the German National Cohort

scientific article

Dietary inflammation potential and postmenopausal breast cancer risk in a German case-control study

scientific article published on 16 May 2015

Dietary patterns and survival in German postmenopausal breast cancer survivors ⬇️

scientific article published on November 20, 2012

Dietary patterns and the risk of postmenopausal breast cancer in a German case–control study ⬇️

scientific article published on November 26, 2010

Dioxins and furans: epidemiologic assessment of cancer risks and other human health effects

scientific article

Elimination of beta-hexachlorocyclohexane in occupationally exposed persons

scientific article published in May 1997

Elimination of polychlorinated dibenzo-p-dioxins and dibenzofurans in occupationally exposed persons

scientific article published on 01 March 1996

Enterolactone concentrations and prognosis after postmenopausal breast cancer: Assessment of effect modification and meta-analysis

article

Estimated enterolignans, lignan-rich foods, and fibre in relation to survival after postmenopausal breast cancer

scientific article published on 13 September 2011

Evaluation of a questionnaire to assess selected infectious diseases and their risk factors : findings of a multicenter study

scientific article

Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors

scientific article published on 27 March 2013

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

scientific article

Exposure to dioxin and nonneoplastic mortality in the expanded IARC international cohort study of phenoxy herbicide and chlorophenol production workers and sprayers

journal article published in 1998

Exposure to polychlorinated dioxins and furans (PCDD/F) and mortality in a cohort of workers from a herbicide-producing plant in Hamburg, Federal Republic of Germany

scientific article published in December 1995

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

scientific article published on February 2014

Fatigue and quality of life in breast cancer survivors: temporal courses and long-term pattern

scientific article published on 11 December 2011

Feasibility and acceptance of cervicovaginal self-sampling within the German National Cohort (Pretest 2)

scientific article

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

scientific article published on 4 February 2015

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

scientific article

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

scientific article

Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium

scientific article

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016

Functional polymorphisms in the TERT promoter are associated with risk of serous epithelial ovarian and breast cancers

scientific article

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

scientific article published on 27 March 2013

Gene-environment interactions involving functional variants: Results from the Breast Cancer Association Consortium

scientific article published on 3 July 2017

Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study

scientific article

Genetic predisposition to in situ and invasive lobular carcinoma of the breast

scientific article

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

scientific article

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade

scientific article

Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium

scientific article published on 30 November 2015

Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent

scientific article (publication date: August 2016)

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Genome-wide association analysis identifies three new breast cancer susceptibility loci

scientific article published on 22 January 2012

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

scientific article

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

scientific article published in April 2013

Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer

scientific article published on 9 December 2013

Genome-wide association study of germline variants and breast cancer-specific mortality

scientific article published on 21 February 2019

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

scientific article published on 23 September 2016

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

scientific article published on 24 April 2017

Germline variants of base excision repair genes and breast cancer: A polymorphism in DNA polymerase gamma modifies gene expression and breast cancer risk ⬇️

scientific article published on June 26, 2012

Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization

scientific article

Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics

scientific article

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

scientific article

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

scientific article published on 27 April 2016

Identification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions

scientific article

Identification of novel genetic markers of breast cancer survival

scientific article published on 18 April 2015

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Immune cell functions in industrial workers after exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: dissociation of antigen-specific T-cell responses in cultures of diluted whole blood and of isolated peripheral blood mononuclear cells.

scientific article published in April 1998

Immunologic findings in workers formerly exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and its congeners

scientific article

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer

scientific article

Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors

scientific article

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

scientific article published in December 2015

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

scientific article

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

scientific article

Menopausal hormone therapy and risk of clinical breast cancer subtypes

scientific article

MicroRNA related polymorphisms and breast cancer risk

scientific article

Mortality and life expectancy of professional fire fighters in Hamburg, Germany: a cohort study 1950-2000

scientific article

Mortality and recurrence risk in relation to the use of lipid-lowering drugs in a prospective breast cancer patient cohort

scientific article (publication date: 2013)

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016

PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1.

scientific article published on 12 October 2017

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

scientific article

Physical activity and postmenopausal breast cancer: effect modification by other breast cancer risk factors

scientific article

Polymorphisms in oxidative stress-related genes and mortality in breast cancer patients – Potential differential effects by radiotherapy?

article

Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk

scientific article

Prediction of breast cancer risk based on profiling with common genetic variants

scientific article published on 8 April 2015

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

scientific article published on 10 April 2018

Quantitative cancer risk assessment for dioxins using an occupational cohort ⬇️

scientific article published on April 1, 1998

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

scientific article

Relationship between menopausal hormone therapy and mortality after breast cancer The MARIEplus study, a prospective case cohort

scientific article

Risk of different histological types of postmenopausal breast cancer by type and regimen of menopausal hormone therapy

scientific article published in August 2008

Serum 25-hydroxyvitamin D and postmenopausal breast cancer survival: a prospective patient cohort study ⬇️

scientific article published on July 26, 2011

Serum 25-hydroxyvitamin D and risk of post-menopausal breast cancer--results of a large case-control study

article by S. Abbas et al published 4 November 2007 in Carcinogenesis

Serum enterolactone and postmenopausal breast cancer risk by estrogen, progesterone and herceptin 2 receptor status

scientific article

Serum enterolactone and prognosis of postmenopausal breast cancer

scientific article published on 6 September 2011

Test-retest reliability of self-reported reproductive and lifestyle data in the context of a German case-control study on breast cancer and postmenopausal hormone therapy

scientific article

The Gc2 allele of the vitamin D binding protein is associated with a decreased postmenopausal breast cancer risk, independent of the vitamin D status

scientific article

The UGT1A6_19_GG genotype is a breast cancer risk factor

scientific article published on 11 June 2013

The association between dietary lignans, phytoestrogen-rich foods, and fiber intake and postmenopausal breast cancer risk: a German case-control study

scientific article published on 16 May 2012

The use of herbal preparations to alleviate climacteric disorders and risk of postmenopausal breast cancer in a German case-control study

scientific article published in August 2009

Vitamin D receptor gene polymorphisms and haplotypes and postmenopausal breast cancer risk

scientific article published on 17 April 2008

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