List of works - Ronald Dijkman

A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets

scientific article

A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets

Assessment of the zoonotic potential of the ruminant-associated influenza D virus

Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission

scientific article published in Scientific Reports

Burden of disease due to human coronavirus NL63 infections and periodicity of infection

scientific article published on 29 March 2010

Characterization of human coronaviruses on well-differentiated human airway epithelial cell cultures

scientific article published on January 2015

Coronaviruses and the human airway: a universal system for virus-host interaction studies

scientific article

Culturing of respiratory viruses in well-differentiated pseudostratified human airway epithelium as a tool to detect unknown viruses

scientific article published on 8 December 2014

Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures

scientific article

Determination of host cell proteins constituting the molecular microenvironment of coronavirus replicase complexes by proximity-labeling

scientific article published on 16 September 2018

Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling

scientific article published on 11 January 2019

Determining the Replication Kinetics and Cellular Tropism of Influenza D Virus on Primary Well-Differentiated Human Airway Epithelial Cells.

scientific article published on 24 April 2019

Differentiation between human coronaviruses NL63 and 229E using a novel double-antibody sandwich enzyme-linked immunosorbent assay based on specific monoclonal antibodies

scientific article

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

scientific article

Disparate temperature-dependent virus – host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

scientific article published on 28 April 2020

Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

scientific article published on 29 March 2021

Efficient inactivation of SARS-CoV-2 by WHO-recommended hand rub formulations and alcohols

scientific article (preprint)

Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential

scientific article

Emergence of a C-terminal seven-amino-acid elongation of NS1 in around 1950 conferred a minor growth advantage to former seasonal influenza A viruses.

scientific article published on 7 August 2013

Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta

scientific article published in February 2022

Establishment of Primary Transgenic Human Airway Epithelial Cell Cultures to Study Respiratory Virus-Host Interactions

scientific article published on 13 August 2019

Establishment of primary transgenic human airway epithelial cell cultures to study respiratory virus – host interactions

scientific article published on 08 July 2019

Fecal shedding of bovine astrovirus CH13/NeuroS1 in veal calves

scientific article published on 26 February 2020

First international external quality assessment of molecular diagnostics for Mers-CoV.

scientific article published on 30 May 2015

Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5

scientific article published on 07 September 2021

H5N1 influenza A virus PB1-F2 relieves HAX-1-mediated restriction of avian virus polymerase PA in human lung cells.

scientific article published on 21 March 2018

Host switching pathogens, infectious outbreaks and zoonosis: A Marie Skłodowska-Curie innovative training network (HONOURs) ⬇️

scientific article published in September 2018

Human bocavirus can be cultured in differentiated human airway epithelial cells

scientific article published on 27 May 2009

Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes

scientific article published on 28 December 2006

Human coronavirus NL63 and 229E seroconversion in children

scientific article published on 21 May 2008

Human coronaviruses 229E and NL63: close yet still so far.

scientific article published on April 2009

Human parechovirus type 1, 3, 4, 5, and 6 detection in picornavirus cultures

scientific article published on 12 December 2007

Identification of an Antiviral Compound from the Pandemic Response Box that Efficiently Inhibits SARS-CoV-2 Infection In Vitro

scientific article published on 26 November 2020

Identification of cell lines permissive for human coronavirus NL63.

scientific article published on 7 September 2006

Identification of five antiviral compounds from the Pandemic Response Box targeting SARS-CoV-2

scientific article published on 18 May 2020

Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols

scientific article published on 13 April 2020

Inhibition of human coronavirus NL63 infection at early stages of the replication cycle

scientific article published on June 2006

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses

scientific article published on 29 October 2013

Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism

scientific article published on 20 February 2013

LY6E impairs coronavirus fusion and confers immune control of viral disease

scientific article (preprint)

LY6E impairs coronavirus fusion and confers immune control of viral disease

scientific article published on 23 July 2020

Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry

scientific article published on 18 March 2020

Link of a ubiquitous human coronavirus to dromedary camels

scientific article published on 15 August 2016

Mosaic structure of human coronavirus NL63, one thousand years of evolution ⬇️

scientific article published on 3 October 2006

Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target

scientific article published in Nature Communications

Prevalence of BRD-Related Viral Pathogens in the Upper Respiratory Tract of Swiss Veal Calves

scientific article published in 2021

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

scientific article (preprint)

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

scientific article published on 04 May 2020

Replication-dependent downregulation of cellular angiotensin-converting enzyme 2 protein expression by human coronavirus NL63.

scientific article

Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination

scientific article

SARS-CoV-2 spike D614G change enhances replication and transmission

scientific article

SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility

scientific article published on 27 October 2020

Seroconversion to HCoV-NL63 in Rhesus Macaques

scientific article

TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium

scientific article published on 27 March 2013

Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus

scientific article published in May 2014

Targeting of the nasal mucosa by Japanese encephalitis virus for non-vector-borne transmission

article

The IFNL4 Gene Is a Noncanonical Interferon Gene with a Unique but Evolutionarily Conserved Regulation

scientific article published on 14 February 2020

The International Virus Bioinformatics Meeting 2020

scientific article published on 06 December 2020

The differentiated airway epithelium infected by influenza viruses maintains the barrier function despite a dramatic loss of ciliated cells.

scientific article published on 22 December 2016

The dominance of human coronavirus OC43 and NL63 infections in infants

article

The first complete genome sequences of clinical isolates of human coronavirus 229E

article by Seyed Mohammad Jazaeri Farsani et al published 25 August 2012 in Virus Genes

The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species

scientific article published on 24 September 2018

The quorum sensing com system regulates pneumococcal colonisation and invasive disease in a pseudo-stratified airway tissue model

scientific article published in 2023

The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

scientific article published in 2022

Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells.

scientific article

Trimeric SARS-CoV-2 Spike Proteins Produced from CHO Cells in Bioreactors Are High-Quality Antigens

scientific article

Using a mouse-adapted A/HK/01/68 influenza virus to analyse the impact of NS1 evolution in codons 196 and 231 on viral replication and virulence

scientific article published on 14 May 2020

Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses

scientific article

Well-Differentiated Primary Mammalian Airway Epithelial Cell Cultures

scientific article published on 01 January 2020

List of works by Ronald Dijkman

A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets

A genome-wide CRISPR screen identifies interactors of the autophagy pathway as conserved coronavirus targets

Assessment of the zoonotic potential of the ruminant-associated influenza D virus

Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission

Burden of disease due to human coronavirus NL63 infections and periodicity of infection

Characterization of human coronaviruses on well-differentiated human airway epithelial cell cultures

Coronaviruses and the human airway: a universal system for virus-host interaction studies

Culturing of respiratory viruses in well-differentiated pseudostratified human airway epithelium as a tool to detect unknown viruses

Culturing the unculturable: human coronavirus HKU1 infects, replicates, and produces progeny virions in human ciliated airway epithelial cell cultures

Determination of host cell proteins constituting the molecular microenvironment of coronavirus replicase complexes by proximity-labeling

Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling

Determining the Replication Kinetics and Cellular Tropism of Influenza D Virus on Primary Well-Differentiated Human Airway Epithelial Cells.

Differentiation between human coronaviruses NL63 and 229E using a novel double-antibody sandwich enzyme-linked immunosorbent assay based on specific monoclonal antibodies

Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

Disparate temperature-dependent virus – host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

Efficient inactivation of SARS-CoV-2 by WHO-recommended hand rub formulations and alcohols

Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential

Emergence of a C-terminal seven-amino-acid elongation of NS1 in around 1950 conferred a minor growth advantage to former seasonal influenza A viruses.

Enhanced fitness of SARS-CoV-2 variant of concern Alpha but not Beta

Establishment of Primary Transgenic Human Airway Epithelial Cell Cultures to Study Respiratory Virus-Host Interactions

Establishment of primary transgenic human airway epithelial cell cultures to study respiratory virus – host interactions

Fecal shedding of bovine astrovirus CH13/NeuroS1 in veal calves

First international external quality assessment of molecular diagnostics for Mers-CoV.

Functional comparison of MERS-coronavirus lineages reveals increased replicative fitness of the recombinant lineage 5

H5N1 influenza A virus PB1-F2 relieves HAX-1-mediated restriction of avian virus polymerase PA in human lung cells.

Host switching pathogens, infectious outbreaks and zoonosis: A Marie Skłodowska-Curie innovative training network (HONOURs) ⬇️

Human bocavirus can be cultured in differentiated human airway epithelial cells

Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes

Human coronavirus NL63 and 229E seroconversion in children

Human coronaviruses 229E and NL63: close yet still so far.

Human parechovirus type 1, 3, 4, 5, and 6 detection in picornavirus cultures

Identification of an Antiviral Compound from the Pandemic Response Box that Efficiently Inhibits SARS-CoV-2 Infection In Vitro

Identification of cell lines permissive for human coronavirus NL63.

Identification of five antiviral compounds from the Pandemic Response Box targeting SARS-CoV-2

Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols

Inhibition of human coronavirus NL63 infection at early stages of the replication cycle

Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses

Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism

LY6E impairs coronavirus fusion and confers immune control of viral disease

LY6E impairs coronavirus fusion and confers immune control of viral disease

Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry

Link of a ubiquitous human coronavirus to dromedary camels

Mosaic structure of human coronavirus NL63, one thousand years of evolution ⬇️

Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target

Prevalence of BRD-Related Viral Pathogens in the Upper Respiratory Tract of Swiss Veal Calves

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

Replication-dependent downregulation of cellular angiotensin-converting enzyme 2 protein expression by human coronavirus NL63.

Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination

SARS-CoV-2 spike D614G change enhances replication and transmission

SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility

Seroconversion to HCoV-NL63 in Rhesus Macaques

TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium

Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus

Targeting of the nasal mucosa by Japanese encephalitis virus for non-vector-borne transmission

The IFNL4 Gene Is a Noncanonical Interferon Gene with a Unique but Evolutionarily Conserved Regulation

The International Virus Bioinformatics Meeting 2020

The differentiated airway epithelium infected by influenza viruses maintains the barrier function despite a dramatic loss of ciliated cells.

The dominance of human coronavirus OC43 and NL63 infections in infants

The first complete genome sequences of clinical isolates of human coronavirus 229E

The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species

The quorum sensing com system regulates pneumococcal colonisation and invasive disease in a pseudo-stratified airway tissue model

The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells.

Trimeric SARS-CoV-2 Spike Proteins Produced from CHO Cells in Bioreactors Are High-Quality Antigens

Using a mouse-adapted A/HK/01/68 influenza virus to analyse the impact of NS1 evolution in codons 196 and 231 on viral replication and virulence

Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses

Well-Differentiated Primary Mammalian Airway Epithelial Cell Cultures