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List of works by Sabine Tejpar

A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 (SMAD4).

scientific article

A let-7 microRNA-binding site polymorphism in KRAS predicts improved outcome in patients with metastatic colorectal cancer treated with salvage cetuximab/panitumumab monotherapy

scientific article

A robust genomic signature for the detection of colorectal cancer patients with microsatellite instability phenotype and high mutation frequency

scientific article

Accomplishments in 2008 in biologic markers for gastrointestinal cancers-focus on colorectal cancer

scientific article published on September 2009

Amphiregulin and epiregulin mRNA expression in primary tumors predicts outcome in metastatic colorectal cancer treated with cetuximab

scientific article published on 08 September 2009

Antitumor activity of pimasertib, a selective MEK 1/2 inhibitor, in combination with PI3K/mTOR inhibitors or with multi-targeted kinase inhibitors in pimasertib-resistant human lung and colorectal cancer cells

scientific article published on 29 May 2013

Assessment of endostatin gene therapy for familial adenomatous polyposis-related desmoid tumors

scientific article published on August 2006

Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab

scientific article

Awareness, Understanding, and Adoption of Precision Medicine to Deliver Personalized Treatment for Patients With Cancer: A Multinational Survey Comparison of Physicians and Patients

scientific article published on 17 February 2016

Beta-catenin overexpression in Dupuytren's disease is unrelated to disease recurrence

scientific article published on 29 October 2008

Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal cancer: interaction of EGFR ligand expression with RAS/RAF, PIK3CA genotypes

scientific article

Biopsies: next-generation biospecimens for tailoring therapy

scientific article published on 25 June 2013

CGH arrays compared for DNA isolated from formalin-fixed, paraffin-embedded material

scientific article published on 08 December 2011

Cell Line Derived 5-FU and Irinotecan Drug-Sensitivity Profiles Evaluated in Adjuvant Colon Cancer Trial Data

scientific article

Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer

scientific article (publication date: 2 April 2009)

Charting the Course for a New Cancer Clinical Research Culture

scientific article published on 20 November 2015

Clinical Validation of Targeted Next Generation Sequencing for Colon and Lung Cancers

scientific article published on 14 September 2015

Clinical biomarkers in oncology: focus on colorectal cancer

scientific article published on January 2009

Clinical usefulness of EGFR gene copy number as a predictive marker in colorectal cancer patients treated with cetuximab: a fluorescent in situ hybridization study

scientific article

Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer

scientific article

Comprehensive pharmacogenetic profiling of the epidermal growth factor receptor pathway for biomarkers of response to, and toxicity from, cetuximab

scientific article

Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer

scientific article

Consensus molecular subtypes and the evolution of precision medicine in colorectal cancer

scientific article published on 4 January 2017

Context-dependent interpretation of the prognostic value of BRAF and KRAS mutations in colorectal cancer

scientific article

Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease

scientific article

DNA Topoisomerase I Gene Copy Number and mRNA Expression Assessed as Predictive Biomarkers for Adjuvant Irinotecan in Stage II/III Colon Cancer

scientific article published on 5 November 2015

DPYD Genotyping to Predict Adverse Events Following Treatment With Flourouracil-Based Adjuvant Chemotherapy in Patients With Stage III Colon Cancer: A Secondary Analysis of the PETACC-8 Randomized Clinical Trial

scientific article published on 21 January 2016

DUSP 4 expression identifies a subset of colorectal cancer tumors that differ in MAPK activation, regardless of the genotype ⬇️

scientific article published on July 22, 2013

EGFR-targeted therapy

scientific article published on 07 September 2011

Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

scientific article

Effects of the EGFR Inhibitor Erlotinib on Magnesium Handling

scientific article published on July 2010

Expression of FOXP1 and Colorectal Cancer Prognosis

scientific article published on January 2015

Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching

scientific article

External quality assessment for KRAS testing is needed: setup of a European program and report of the first joined regional quality assessment rounds

scientific article published on 26 March 2011

Familial adenomatous polyposis-associated desmoids display significantly more genetic changes than sporadic desmoids

scientific article

Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells

scientific article published on 09 December 2016

Gene expression patterns unveil a new level of molecular heterogeneity in colorectal cancer ⬇️

scientific article published on 08 July 2013

Hypomagnesaemia and targeted anti-epidermal growth factor receptor (EGFR) agents ⬇️

scientific article published on November 24, 2011

ICECREAM: randomised phase II study of cetuximab alone or in combination with irinotecan in patients with metastatic colorectal cancer with either KRAS, NRAS, BRAF and PI3KCA wild type, or G13D mutated tumours

scientific article

Immunohistochemical evidence for Zic1 coexpression with beta-catenin in the myofibroblast of Dupuytren disease

scientific article

Impact of molecular markers on treatment selection in advanced colorectal cancer

scientific article published on September 2009

Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia

scientific article published in August 2007

Improved postoperative outcome of segmental fasciectomy in Dupuytren disease by insertion of an absorbable cellulose implant ⬇️

scientific article published on June 1, 2011

Integrating biomarkers in colorectal cancer trials in the West and China

scientific article published on 12 May 2015

KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy

scientific article

Magnesium wasting associated with epidermal-growth-factor receptor-targeting antibodies in colorectal cancer: a prospective study

scientific article published on May 2007

Managing synchronous liver metastases from colorectal cancer: a multidisciplinary international consensus

scientific article

Molecular and genetic defects in colorectal tumorigenesis

scientific article

Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes

scientific article

New strategies for treatment of KRAS mutant metastatic colorectal cancer

scientific article published on 11 May 2010

Oral capecitabine: bridging the Atlantic divide in colon cancer treatment

scientific article

Overcoming resistance to antiangiogenic therapies

scientific article published on 06 July 2012

Personalized medicine in metastatic colorectal cancer treated with anti-epidermal growth factor receptor agents: a future opportunity?

scientific article published on March 2014

Personalized treatment is better than one treatment fits all in the management of patients with mCRC: a consensus statement

scientific article published on December 2014

Phase II open-label study to assess efficacy and safety of lenalidomide in combination with cetuximab in KRAS-mutant metastatic colorectal cancer

scientific article (publication date: 2013)

Prognostic and Predictive Relevance of Primary Tumor Location in Patients With RAS Wild-Type Metastatic Colorectal Cancer: Retrospective Analyses of the CRYSTAL and FIRE-3 Trials

scientific article published on 10 October 2016

Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery

scientific article published on 29 March 2010

Prostatic biopsy-related rectal bleeding refractory to medical and endoscopic therapy definitively managed by catheter-directed embolotherapy: a case report

scientific article published on 29 October 2015

Putative contribution of CD56 positive cells in cetuximab treatment efficacy in first-line metastatic colorectal cancer patients

scientific article

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

scientific article published on 13 February 2013

Single Nucleotide Polymorphism (rs4932178) in the P1 Promoter of FURIN Is Not Prognostic to Colon Cancer

scientific article published on 7 June 2015

Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study

scientific article published on 20 July 2016

TGF-beta modulates beta-Catenin stability and signaling in mesenchymal proliferations

scientific article

Targeted therapies: how personal should we go?

scientific article

Test of four colon cancer risk-scores in formalin fixed paraffin embedded microarray gene expression data

scientific article

The ZIC gene family encodes multi-functional proteins essential for patterning and morphogenesis ⬇️

scientific article published on February 27, 2013

The consensus molecular subtypes of colorectal cancer

scientific article

The human alphaE-catenin gene CTNNA1: mutational analysis and rare occurrence of a truncated splice variant

scientific article

The multidisciplinary management of gastrointestinal cancer. The use of molecular markers in the diagnosis and treatment of colorectal cancer

scientific article published on January 2007

The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling

scientific article

Therapeutic potential of replication-selective oncolytic adenoviruses on cells from familial and sporadic desmoid tumors

scientific article published on October 2008

Transcription factor Zic2 inhibits Wnt/β-catenin protein signaling

scientific article

Understanding the role of primary tumour localisation in colorectal cancer treatment and outcomes

scientific article published on 05 August 2017

Upregulation of Wilms' tumor gene 1 (WT1) in desmoid tumors

scientific article

VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials

scientific article

Virtual chromoendoscopy (I-SCAN) detects more polyps in patients with Lynch syndrome: a randomized controlled crossover trial

scientific article published on 20 January 2017

ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations

scientific article

miR-345 in metastatic colorectal cancer: a non-invasive biomarker for clinical outcome in non-KRAS mutant patients treated with 3rd line cetuximab and irinotecan

scientific article

microRNAs in colon cancer: a roadmap for discovery

scientific article published on September 2012

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