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List of works by Geert D'Haens

A Systematic Review for the Development of a Core Outcome Set for Ulcerative Colitis Clinical Trials

scientific article

A composite disease activity index for early drug development in ulcerative colitis: development and validation of the UC-100 score

article

A global consensus on the classification, diagnosis and multidisciplinary treatment of perianal fistulising Crohn's disease.

scientific article

A multicentre prospective cohort study assessing the effectiveness of budesonide MMX® (Cortiment®MMX®) for active, mild-to-moderate ulcerative colitis

scientific article published on 17 July 2019

A novel intravenous iron formulation for treatment of anemia in inflammatory bowel disease: the ferric carboxymaltose (FERINJECT) randomized controlled trial

scientific article

A phase II study of laquinimod in Crohn's disease

scientific article published on 3 October 2014

A retrospective analysis: the development of patient reported outcome measures for the assessment of Crohn's disease activity

scientific article published on 27 October 2014

A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis

scientific article published on 20 December 2006

A simple classification of Crohn's disease: Report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998

scientific article

Acute severe ulcerative colitis: from pathophysiology to clinical management

scientific article

Adalimumab Effectiveness Up to Six Years in Adalimumab-naïve Patients with Crohn's Disease: Results of the PYRAMID Registry

scientific article published on 01 August 2019

Adalimumab Induces and Maintains Clinical Remission in Patients With Moderate-to-Severe Ulcerative Colitis ⬇️

scientific article published on November 4, 2011

Adalimumab Induces and Maintains Mucosal Healing in Patients With Crohn's Disease: Data From the EXTEND Trial ⬇️

scientific article published on February 8, 2012

Adalimumab dose escalation and dose de-escalation success rate and predictors in a large national cohort of Crohn's patients ⬇️

scientific article published on April 24, 2012

Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial

scientific article published on 05 January 2011

Adalimumab for the treatment of fistulas in patients with Crohn's disease

scientific article published on 06 February 2009

Adalimumab induction therapy for Crohn disease previously treated with infliximab: a randomized trial

scientific article published on 30 April 2007

Adalimumab sustains clinical remission and overall clinical benefit after 2 years of therapy for Crohn's disease

scientific article

Advances in biologic therapy for ulcerative colitis and Crohn's disease

scientific article published on December 2006

Advances in medical therapy for Crohn's disease

scientific article

Agreement of site and central readings of ileocolonoscopic scores in Crohn's disease: comparison using data from the EXTEND trial

scientific article

An expert consensus to standardise the assessment of histological disease activity in Crohn's disease clinical trials

scientific article published on 07 January 2021

Anti-TNF therapy for Crohn's disease

scientific article

Antibody development against biologic agents used for the treatment of inflammatory bowel disease and antibody prevention with immunosuppressives

scientific article

Assessment of histologic disease activity in Crohn's disease: a systematic review

scientific article

Assessment of mucosal healing in inflammatory bowel disease: review.

scientific article published on 21 May 2015

Association between plasma concentrations of certolizumab pegol and endoscopic outcomes of patients with Crohn's disease.

scientific article

Association of Biomarker Cutoffs and Endoscopic Outcomes in Crohn's Disease: A Post Hoc Analysis From the CALM Study

scientific article published on 27 February 2020

Azathioprine and 6-mercaptopurine for the prevention of postoperative recurrence in Crohn's disease: a meta-analysis

scientific article published on 30 June 2009

Biosimilars for inflammatory bowel disease: how can healthcare professionals help address patients' concerns?

scientific article published on 17 January 2019

Biosimilars in IBD: hope or expectation?

scientific article published on 16 March 2013

Budesonide MMX for the Induction of Remission of Mild to Moderate Ulcerative Colitis: A Pooled Safety Analysis

scientific article published on 20 June 2015

Budesonide in collagenous colitis: a double-blind placebo-controlled trial with histologic follow-up

scientific article published on January 2002

Capsule Retention in Crohn's Disease: A Meta-analysis

scientific article published on 01 January 2020

Centrally Determined Standardization of Flow Cytometry Methods Reduces Interlaboratory Variation in a Prospective Multicenter Study

scientific article published on 2 November 2017

Certolizumab pegol for active Crohn's disease: a placebo-controlled, randomized trial

scientific article

Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab

scientific article published on 6 May 2010

Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer

scientific article (publication date: 2 April 2009)

Challenges in the Pathophysiology, Diagnosis and Management of Intestinal Fibrosis in Inflammatory Bowel Disease

scientific article published on 26 June 2019

Challenges to the design, execution, and analysis of randomized controlled trials for inflammatory bowel disease

scientific article published on 20 September 2012

Changes in health-related quality of life and work-related outcomes for patients with mild-to-moderate ulcerative colitis receiving short-term and long-term treatment with multimatrix mesalamine: a prospective, open-label study

article

Characterisation of Mucosal Healing with Adalimumab Treatment in Patients with Moderately to Severely Active Crohn's Disease: Results from the EXTEND Trial

scientific article published on 10 October 2016

Chromoendoscopy versus autofluorescence imaging for neoplasia detection in patients with longstanding ulcerative colitis (FIND-UC): an international, multicentre, randomised controlled trial.

scientific article

Clinical Benefit of Long-Term Adalimumab Treatment in Patients With Crohn's Disease Following Loss of Response or Intolerance to Infliximab: 96-Week Efficacy Data From GAIN/ADHERE Trials

scientific article

Clinical disease activity in the CALM study - Authors' reply

scientific article published on 01 April 2018

Combination Immunosuppression in IBD.

scientific article published in February 2018

Combination Therapy With Infliximab and Azathioprine Improves Infliximab Pharmacokinetic Features and Efficacy: A Post Hoc Analysis

scientific article published on 26 September 2018

Comparison of six different calprotectin assays for the assessment of inflammatory bowel disease

scientific article

Correlation of Stool Frequency and Abdominal Pain Measures With Simple Endoscopic Score for Crohn's Disease

scientific article published on 01 January 2020

Corrigendum: Evolving Concepts in Phases I and II Drug Development for Crohn's Disease

scientific article published on 01 April 2018

Corrigendum: Responsiveness of Endoscopic Indices of Disease Activity for Crohn's Disease

scientific article published on 18 April 2017

Current misunderstandings in the management of ulcerative colitis ⬇️

scientific article published on April 19, 2011

Deep Remission at 1 Year Prevents Progression of Early Crohn's Disease

scientific article published on 25 March 2020

Demographic and clinical parameters influencing the short-term outcome of anti-tumor necrosis factor (infliximab) treatment in Crohn's disease

scientific article published on 01 September 2002

Development and Validation of a Magnetic Resonance Index for Assessing Fistulas in Patients With Crohn's Disease

scientific article published on 20 July 2019

Development and Validation of a Test to Monitor Endoscopic Activity in Patients With Crohn's Disease Based on Serum Levels of Proteins

scientific article published on 08 November 2019

Development and validation of a histological index for UC.

scientific article

Development and validation of a new, simplified endoscopic activity score for Crohn's disease: the SES-CD

scientific article published on 01 October 2004

Development of Red Flags Index for Early Referral of Adults with Symptoms and Signs Suggestive of Crohn's Disease: An IOIBD Initiative

scientific article published on 23 April 2015

Development of an index to define overall disease severity in IBD.

scientific article published on 25 October 2016

Development of interim patient-reported outcome measures for the assessment of ulcerative colitis disease activity in clinical trials

scientific article published on 21 September 2015

Development of the Crohn's disease digestive damage score, the Lémann score

scientific article published on 28 November 2010

Development of the Lémann index to assess digestive tract damage in patients with Crohn's disease.

scientific article published on 21 September 2014

Development of the Paris definition of early Crohn's disease for disease-modification trials: results of an international expert opinion process

scientific article published on December 2012

Diagnostic Accuracy of Endoscopic Trimodal Imaging and Chromoendoscopy for Lesion Characterization in Ulcerative Colitis

scientific article published on 01 December 2019

Diagnostic accuracy of Endoscopic Trimodal Imaging and Chromoendoscopy for lesion characterisation in ulcerative colitis surveillance: ETMI or chromoendoscopy for lesion characterisation in colitis

scientific article published on 01 November 2018

Disease activity indices in coeliac disease: systematic review and recommendations for clinical trials

scientific article

Early combined immunosuppression for the management of Crohn's disease (REACT): a cluster randomised controlled trial

scientific article published on 2 September 2015

Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial

scientific article published in February 2008

Effect of PF-00547659 on Central Nervous System Immune Surveillance and Circulating β7+ T Cells in Crohn's Disease: Report of the TOSCA Study

scientific article published on 16 September 2017

Effect of Standardised Scoring Conventions on Inter-rater Reliability in the Endoscopic Evaluation of Crohn's Disease

scientific article published on 6 July 2016

Effect of tight control management on Crohn's disease (CALM): a multicentre, randomised, controlled phase 3 trial

scientific article published on 30 October 2017

Effectiveness and safety of switching IBD patients from the originator to the biosimilar infliximab

Effectiveness of budesonide MMX (Cortiment) for the treatment of mild-to-moderate active ulcerative colitis: study protocol for a prospective multicentre observational cohort study

scientific article published on 17 May 2016

Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease

scientific article

Effects of adalimumab therapy on incidence of hospitalization and surgery in Crohn's disease: results from the CHARM study

scientific article

Effects of vedolizumab induction therapy for patients with Crohn's disease in whom tumor necrosis factor antagonist treatment failed

scientific article published on 21 May 2014

Efficacy and Safety of Upadacitinib in a Randomized Trial of Patients With Crohn's Disease

scientific article published on 07 February 2020

Efficacy and Safety of Vedolizumab Subcutaneous Formulation in a Randomized Trial of Patients With Ulcerative Colitis

scientific article published on 28 August 2019

Efficacy of Endoscopic Dilation of Gastroduodenal Crohn's Disease Strictures: A Systematic Review and Meta-Analysis of Individual Patient Data

scientific article published on 29 November 2018

Efficacy of Upadacitinib in a Randomized Trial of Patients With Active Ulcerative Colitis

scientific article published on 21 February 2020

Efficacy of infliximab in refractory pouchitis and Crohn's disease-related complications of the pouch: a Belgian case series

scientific article

Efficient Early Drug Development for Ulcerative Colitis

scientific article published on 24 March 2016

Endoscopic improvement of mucosal lesions in patients with moderate to severe ileocolonic Crohn's disease following treatment with certolizumab pegol

scientific article published on 23 April 2012

Endoscopic scoring indices for evaluation of disease activity in Crohn’s disease

scientific article

Endoscopic scoring indices for evaluation of disease activity in Crohn’s disease

scientific article (publication date: 8 August 2016)

Endoscopic scoring indices for evaluation of disease activity in ulcerative colitis

scientific article

Endoscopy in Inflammatory Bowel Diseases

Endpoints for clinical trials evaluating disease modification and structural damage in adults with Crohn's disease

scientific article published on October 2009

Erratum: Corrigendum: The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD With the European Crohn's and Colitis Organization: When to Start, When to Stop, Which Drug to Choose and How to Predict Respo

article

Evaluation of optimal biopsy location for assessment of histological activity, transcriptomic and immunohistochemical analyses in patients with active Crohn's disease

scientific article published on 15 April 2019

Evolving Concepts in Phases I and II Drug Development for Crohn's Disease

scientific article

Fc Receptor-mediated Effector Function Contributes to the Therapeutic Response of Anti-TNF Monoclonal Antibodies in a Mouse Model of Inflammatory Bowel Disease.

scientific article

Fecal calprotectin is a surrogate marker for endoscopic lesions in inflammatory bowel disease

scientific article

Fistulizing Crohn's disease: Diagnosis and management.

scientific article published on June 2013

Five-year Safety Data From ENCORE, a European Observational Safety Registry for Adults With Crohn's Disease Treated With Infliximab [Remicade®] or Conventional Therapy

scientific article

Health-Related Quality of Life and Work-Related Outcomes for Patients With Mild-to-Moderate Ulcerative Colitis and Remission Status Following Short-Term and Long-Term Treatment With Multimatrix Mesalamine: A Prospective, Open-Label Study.

scientific article published in January 2018

Heterogeneity in Definitions of Efficacy and Safety Endpoints for Clinical Trials of Crohn's Disease: A Systematic Review for Development of a Core Outcome Set.

scientific article published on 26 March 2018

Histologic scoring indices for evaluation of disease activity in Crohn's disease.

scientific article published on 21 July 2017

Histologic scoring indices for evaluation of disease activity in Crohn’s disease

Histologic scoring indices for evaluation of disease activity in ulcerative colitis

scientific article

How to Manage Crohn's Disease After Ileocolonic Resection?

scientific article published on 14 June 2020

IBD Around the world: comparing the epidemiology, diagnosis, and treatment: proceedings of the World Digestive Health Day 2010--Inflammatory Bowel Disease Task Force meeting

scientific article published in February 2011

IOIBD technical review on endoscopic indices for Crohn's disease clinical trials

scientific article published on 09 September 2015

Identification of Endpoints for Development of Antifibrosis Drugs for Treatment of Crohn’s Disease

article

Immunosuppression-associated lymphoma in IBD

scientific article published on 01 November 2009

Impact of disease location on fecal calprotectin levels in Crohn's disease

scientific article published on 30 January 2015

Increasing Infliximab Dose Based on Symptoms, Biomarkers, and Serum Drug Concentrations Does Not Increase Clinical, Endoscopic, or Corticosteroid-Free Remission in Patients With Active Luminal Crohn's Disease.

scientific article published on 6 January 2018

Induction therapy with the selective interleukin-23 inhibitor risankizumab in patients with moderate-to-severe Crohn's disease: a randomised, double-blind, placebo-controlled phase 2 study

scientific article published on 12 April 2017

Infliximab Exposure Associates With Radiologic Evidence of Healing in Patients With Crohn's Disease

scientific article published on 28 April 2020

Infliximab, azathioprine, or combination therapy for Crohn's disease

article

Intestinal Ultrasound to Assess Disease Activity in Ulcerative Colitis: Development of a novel UC-Ultrasound index

scientific article published on 07 January 2021

Intestinal and hepatic fibrosis: how are they similar?

scientific article published on 01 November 2019

Long-term Efficacy of Vedolizumab for Crohn's Disease

scientific article published on 28 September 2016

Long-term Efficacy of Vedolizumab for Ulcerative Colitis

scientific article published on 28 September 2016

Long-term effectiveness of azathioprine in IBD beyond 4 years: a European multicenter study in 1176 patients

scientific article published on 22 August 2006

Long-term outcome of treatment with intravenous cyclosporin in patients with severe ulcerative colitis

scientific article published in March 2004

Long-term safety of vedolizumab for inflammatory bowel disease

scientific article published on 02 September 2020

MRI scoring indices for evaluation of disease activity and severity in Crohn’s disease

scientific article

Mesalamine foam enema versus mesalamine liquid enema in active left-sided ulcerative colitis.

scientific article

Modelling of the Relationship Between Infliximab Exposure, Faecal Calprotectin, and Endoscopic Remission in Patients with Crohn's Disease

scientific article published on 15 May 2020

Monitoring a Combination of Calprotectin and Infliximab Identifies Patients With Mucosal Healing of Crohn's Disease

scientific article published on 22 May 2019

Mucosal healing in Crohn's disease: relevance for clinical outcomes

scientific article published on September 2012

Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease

scientific article published on 8 October 2009

Novel Therapies and Treatment Strategies for Patients with Inflammatory Bowel Disease

scientific article published on 6 February 2018

Novel targets for inflammatory bowel disease therapeutics

scientific article published on February 2013

Oestrogens promote tumorigenesis in a mouse model for colitis-associated cancer.

scientific article published on 13 February 2013

Omega-3 free fatty acids for the maintenance of remission in Crohn disease: the EPIC Randomized Controlled Trials

scientific article published on April 2008

Once-Daily MMX® Mesalamine for Endoscopic Maintenance of Remission of Ulcerative Colitis ⬇️

scientific article published on May 8, 2012

Once-daily budesonide MMX in active, mild-to-moderate ulcerative colitis: results from the randomised CORE II study

scientific article published on 22 February 2013

Optimising monitoring in the management of Crohn's disease: a physician's perspective

scientific article

Optimizing biologic therapies for inflammatory bowel disease (ulcerative colitis and Crohn's disease).

scientific article published on December 2009

Oral p38 mitogen-activated protein kinase inhibition with BIRB 796 for active Crohn's disease: a randomized, double-blind, placebo-controlled trial

scientific article published on 01 March 2006

Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial

scientific article

Outcomes and Strategies to Support a Treat-to-target Approach in Inflammatory Bowel Disease: A Systematic Review

scientific article published on 01 February 2020

Ozanimod Induction and Maintenance Treatment for Ulcerative Colitis

scientific article

Ozanimod induction therapy for patients with moderate to severe Crohn's disease: a single-arm, phase 2, prospective observer-blinded endpoint study

scientific article published on 15 June 2020

Phase I, double-blind, randomized, placebo-controlled, dose-escalation study of NI-0401 (a fully human anti-CD3 monoclonal antibody) in patients with moderate to severe active Crohnʼs disease†

scientific article published on 01 October 2010

Phase II evaluation of anti-MAdCAM antibody PF-00547659 in the treatment of Crohn's disease: report of the OPERA study

scientific article published on 5 October 2017

Placebo response and remission rates in randomised trials of induction and maintenance therapy for Crohn’s disease

scientific article

Placebo response and remission rates in randomised trials of induction and maintenance therapy for Crohn’s disease

scientific article published on 16 January 2017

Placebo response and remission rates in randomised trials of induction and maintenance therapy for ulcerative colitis

scientific article published on 8 September 2017

Placebo response and remission rates in randomized trials of induction and maintenance therapy for ulcerative colitis

scientific article

Prevalence of endoscopic improvement and remission according to patient-reported outcomes in ulcerative colitis

scientific article published on 22 November 2019

Prevalence of- and risk factors for work disability in Dutch patients with inflammatory bowel disease

scientific article published in December 2017

Randomised clinical trial: vercirnon, an oral CCR9 antagonist, vs. placebo as induction therapy in active Crohn's disease

scientific article published on 23 September 2015

Randomized, double-blind comparison of 4 mg/kg versus 2 mg/kg intravenous cyclosporine in severe ulcerative colitis1 1Gert Van Assche, Severine Vermeire, Geert D’Haens, and Paul Rutgeerts have been instrumental in the design of the study, trial man

scientific article published on 01 October 2003

Recommendations for the treatment of Crohn's disease with tumor necrosis factor antagonists: an expert consensus report

scientific article

Recommendations for the treatment of ulcerative colitis with infliximab: a gastroenterology expert group consensus

scientific article

Reliability among central readers in the evaluation of endoscopic disease activity in pouchitis

Reliability among central readers in the evaluation of endoscopic findings from patients with Crohn's disease

scientific article published on 2 May 2015

Reliability of Endoscopic Evaluation of Postoperative Recurrent Crohn's Disease

scientific article published on 29 August 2019

Reliability of Measuring Ileo-Colonic Disease Activity in Crohn's Disease by Magnetic Resonance Enterography

scientific article

Reliability of histologic assessment in patients with eosinophilic oesophagitis.

scientific article published on 20 February 2018

Reply

Reply to Falvey et al.

scientific article published in May 2013

Reproducibility of histological assessments of disease activity in UC.

scientific article

Response to Letter to the Editor

scientific article published on 18 March 2020

Responsiveness of Endoscopic Indices of Disease Activity for Crohn's Disease

scientific article published on 10 January 2017

Responsiveness of histological disease activity indices in ulcerative colitis: a post hoc analysis using data from the TOUCHSTONE randomised controlled trial

scientific article published on 03 August 2018

Results of the 2nd scientific workshop of the ECCO (IV): therapeutic strategies to enhance intestinal healing in inflammatory bowel disease

scientific article published on 09 March 2012

Risks and benefits of biologic therapy for inflammatory bowel diseases

scientific article published in May 2007

Safety and Feasibility of Using the Second-Generation Pillcam Colon Capsule to Assess Active Colonic Crohn's Disease

scientific article published on 21 March 2015

Significant differences between Crohn's disease and ulcerative colitis regarding the impact of body mass index and initial disease activity on responsiveness to azathioprine: results from a European multicenter study in 1,176 patients

scientific article published on 10 June 2009

Switch to adalimumab in patients with Crohn's disease controlled by maintenance infliximab: prospective randomised SWITCH trial

article by Gert Van Assche et al published 23 September 2011 in Gut

Systematic Review and Meta-analysis: Placebo Rates in Induction and Maintenance Trials of Ulcerative Colitis

scientific article published on 7 January 2016

Systematic Review: Disease Activity Indices in Eosinophilic Esophagitis

scientific article

Systematic review with meta-analysis: endoscopic and histologic placebo rates in induction and maintenance trials of ulcerative colitis

scientific article published on 25 April 2018

Systematic versus Endoscopy-driven Treatment with Azathioprine to Prevent Postoperative Ileal Crohn's Disease Recurrence

scientific article published on 29 April 2015

The Crohn's Disease-Ulcerative Colitis Clinical Appraisal

scientific article published on 2 February 2016

The Crohn's Disease-Ulcerative Colitis Clinical Appraisal Update: Emerging Trends in Clinical Practice

scientific article published on 24 July 2016

The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response?

scientific article

The Value of Myenteric Plexitis to Predict Early Postoperative Crohn’s Disease Recurrence

scientific article published on 01 May 2006

The development of a magnetic resonance imaging index for fistulising Crohn's disease

scientific article published on 27 June 2017

The expanding therapeutic armamentarium for inflammatory bowel disease: how to choose the right drug(s) for our patients?

scientific article published on 25 August 2017

The risk of post-operative complications associated with infliximab therapy for Crohn's disease: a controlled cohort study

scientific article published in April 2004

The role of aminosalicylates in the treatment of ulcerative colitis

scientific article published in October 2002

The role of centralized reading of endoscopy in a randomized controlled trial of mesalamine for ulcerative colitis

scientific article published on 22 March 2013

The safety of vedolizumab for ulcerative colitis and Crohn's disease

scientific article

The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Special situations

scientific article

Therapy of Metronidazole With Azathioprine to Prevent Postoperative Recurrence of Crohn's Disease: A Controlled Randomized Trial

article by Geert R. D'Haens et al published October 2008 in Gastroenterology

Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis

scientific article published on May 2017

Tofacitinib for induction and maintenance therapy of Crohn's disease: results of two phase IIb randomised placebo-controlled trials

scientific article published on 16 February 2017

Treatment of small bowel subocclusive Crohn's disease with infliximab: an open pilot study

scientific article published on 01 January 2007

Ulcerative Colitis Remission Status After Induction With Mesalazine Predicts Maintenance Outcomes: the MOMENTUM Trial

scientific article published on 23 February 2016

Ulcerative Colitis: Shifting Sands

scientific article published on 01 June 2019

Validation of endoscopic activity scores in patients with Crohn's disease based on a post hoc analysis of data from SONIC.

scientific article

Vedolizumab Induces Endoscopic and Histologic Remission in Patients With Crohn's Disease

scientific article published on 05 June 2019

What do changes in inflammatory bowel disease management mean for our patients?

scientific article published on February 2012

Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: a randomized trial

scientific article published on 8 March 2008

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