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List of works by Gert Van Assche

(Auto)antibodies in inflammatory bowel diseases

scientific article published in June 2008

3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn's Disease 2016: Part 1: Diagnosis and Medical Management

scientific article published on 22 September 2016

5-Aminosalicylate is Not Protective From Neoplasia in Ulcerative Colitis

scholarly article by Talat Bessissow et al published June 2013 in The American Journal of Gastroenterology

A Simplified Geboes Score for Ulcerative Colitis

scientific article published in March 2017

A panel to predict long-term outcome of infliximab therapy for patients with ulcerative colitis

scientific article

A phase I study of visilizumab, a humanized anti-CD3 monoclonal antibody, in severe steroid-refractory ulcerative colitis

scientific article published on 21 August 2007

A safety assessment of biological therapies targeting the IL-23/IL-17 axis in inflammatory bowel diseases

scientific article published on 2 June 2017

Adalimumab Induces and Maintains Mucosal Healing in Patients With Crohn's Disease: Data From the EXTEND Trial

scientific article published on February 8, 2012

Adalimumab dose escalation and dose de-escalation success rate and predictors in a large national cohort of Crohn's patients

scientific article published on April 24, 2012

Adalimumab in Crohn's disease

scientific article published on December 2007

Aeromonas species: an opportunistic enteropathogen in patients with inflammatory bowel diseases? A single center cohort study

scientific article published on January 2015

Anti-CD3 antibody visilizumab is not effective in patients with intravenous corticosteroid-refractory ulcerative colitis

scientific article

Anti-Tumor Necrosis Factor Therapy Restores Peripheral Blood B-cell Subsets and CD40 Expression in Inflammatory Bowel Diseases

scientific article published on 16 September 2015

Anti-tumor necrosis factor treatment restores the gut barrier in Crohn's disease

scientific article

Anxiety is associated with impaired tolerance of colonoscopy preparation in inflammatory bowel disease and controls

scientific article published on 9 May 2013

Assessment of the microbiota in microdissected tissues of Crohn's disease patients

scientific article

Autoimmunity associated with anti-tumor necrosis factor alpha treatment in Crohn's disease: a prospective cohort study

scientific article

Balloon dilatation of ileo-colonic anastomosis in Crohn's disease

scientific article

Balloon dilation of intrinsic small bowel strictures, still doubts about its efficacy?

scientific article published on 25 January 2018

Biological therapies for inflammatory bowel diseases

scientific article published on 26 February 2009

Biological therapy targeting the IL-23/IL-17 axis in inflammatory bowel disease

scientific article published on 6 November 2016

Burden of disease and patient-reported outcomes in patients with moderate to severe ulcerative colitis in the last 12 months - Multicenter European cohort study

scientific article published on 29 January 2016

C-reactive protein as a marker for inflammatory bowel disease

scientific article published in September 2004

CXCR1-binding chemokines in inflammatory bowel diseases: down-regulated IL-8/CXCL8 production by leukocytes in Crohn's disease and selective GCP-2/CXCL6 expression in inflamed intestinal tissue

scientific article published in July 2004

Cancer risk in immune-mediated inflammatory diseases (IMID).

scientific article published on 29 August 2013

Caspase activation and apoptosis induction by adalimumab: demonstration in vitro and in vivo in a chimeric mouse model

scientific article published on January 2006

Chromoendoscopy versus narrow band imaging in UC: a prospective randomised controlled trial

scientific article published on 11 July 2017

Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial

scientific article

Classification of inflammatory bowel disease: the old and the new.

scientific article published on July 2012

Clinical relevance of detecting anti-infliximab antibodies with a drug-tolerant assay: post hoc analysis of the TAXIT trial

scientific article published on 27 April 2017

Clustering of (auto)immune diseases with early-onset and complicated inflammatory bowel disease

scientific article published in August 2008

Consensus recommendations for patient-centered therapy in mild-to-moderate ulcerative colitis: the i Support Therapy-Access to Rapid Treatment (iSTART) approach

Correlation Between the Endoscopic and Histologic Score in Assessing the Activity of Ulcerative Colitis

scholarly article by Bart Lemmens et al published May 2013 in Inflammatory Bowel Diseases

Corrigendum to “Rectal non-Hodgkin's lymphoma in an infliximab treated patient with ulcerative colitis and primary sclerosing cholangitis” [J Crohn's and Colitis 4 (2010) 683–6. Epub 2010 Jul 14]

scholarly article published in Journal of Crohn's and Colitis

Crohn's Disease

Dealing With Infusion Reactions

Development of pouchitis following ileal pouch-anal anastomosis (IPAA) for ulcerative colitis: A role for serological markers and microbial pattern recognition receptor genes

scientific article published on 26 November 2007

Donor Species Richness Determines Faecal Microbiota Transplantation Success in Inflammatory Bowel Disease

scientific article published on 29 October 2015

Effect of vedolizumab (anti-α4β7-integrin) therapy on histological healing and mucosal gene expression in patients with UC.

scientific article published on 7 October 2016

Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease

scientific article

Effects of Education and Information on Vaccination Behavior in Patients with Inflammatory Bowel Disease

scientific article published on 10 January 2017

Effects of Epithelial IL-13Rα2 Expression in Inflammatory Bowel Disease

Effects of T cell-induced colonic inflammation on epithelial barrier function

scientific article published in August 2010

Effects of infliximab therapy on transmural lesions as assessed by magnetic resonance enteroclysis in patients with ileal Crohn's disease

scientific article published on 12 February 2013

Effects of introduction of an inflammatory bowel disease nurse position on the quality of delivered care

scientific article published on 21 January 2017

Efficacy of infliximab in refractory pouchitis and Crohn's disease-related complications of the pouch: a Belgian case series

scientific article

Emerging biological treatments in inflammatory bowel diseases

scientific article

Endoscopic and medical management of fibrostenotic Crohn's disease

scientific article published on 17 December 2014

Endoscopic management of Crohn's strictures

scientific article

Endoscopic therapy of strictures in Crohn's disease

scientific article published on March 2007

Endoscopy in Inflammatory Bowel Diseases

Epithelial organoid cultures from patients with ulcerative colitis and Crohn's disease: a truly long-term model to study the molecular basis for inflammatory bowel disease?

scientific article published on 3 February 2017

Evolution of cytokines and inflammatory biomarkers during infliximab induction therapy and the impact of inflammatory burden on primary response in patients with Crohn's disease

scientific article published on 16 June 2017

Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial

scientific article published on 28 July 2016

Extracorporeal photopheresis for the treatment of refractory Crohn's disease: results of an open-label pilot study

scientific article published in June 2009

Fecal biomarkers for the diagnosis and management of inflammatory bowel disease

scientific article published on June 1, 2011

Fecal calprotectin is a surrogate marker for endoscopic lesions in inflammatory bowel disease

scientific article

Focus on mechanisms of inflammation in inflammatory bowel disease sites of inhibition: current and future therapies

scientific article published on December 2006

Functional expression of 4-1BB (CD137) in the inflammatory tissue in Crohn's disease

scientific article published in September 2004

Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress.

scientific article

Genetic variants in autophagy-related genes and granuloma formation in a cohort of surgically treated Crohn's disease patients

article

Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases

scientific article

Identifying predictors of low adherence in patients with inflammatory bowel disease

scientific article

IgG1 heavy chain-coding gene polymorphism (G1m allotypes) and development of antibodies-to-infliximab

scientific article published in May 2009

Immunogenicity to infliximab is associated with HLA-DRB1.

scientific article published on 15 April 2015

Immunosuppression in inflammatory bowel disease: traditional, biological or both?

scientific article published on July 2009

Implementing the Concept of Continuous Clinical Response Into Clinical Practice for Ulcerative Colitis

scientific article

Incidence of colectomy during long-term follow-up after cyclosporine-induced remission of severe ulcerative colitis

scientific article published on 22 May 2006

Incidence of renal cell carcinoma in inflammatory bowel disease patients with and without anti-TNF treatment

scientific article published on 3 September 2016

Increasing incidence of Clostridium difficile-associated diarrhea in inflammatory bowel disease

article published in 2009

Inflammatory bowel disease and colitis: new concepts from the bench and the clinic

scientific article published on January 2011

Infliximab Concentration Thresholds During Induction Therapy Are Associated With Short-term Mucosal Healing in Patients With Ulcerative Colitis

scientific article published on 8 December 2015

Infliximab Therapy

Infliximab administered with shortened infusion times in a specialized IBD infusion unit: a prospective cohort study

scientific article

Infliximab induces apoptosis of monocytes and T lymphocytes in a human-mouse chimeric model

scientific article

Infliximab therapy for patients with inflammatory bowel disease: 10 years on.

scientific article published on 18 October 2009

Infliximab: the evidence for its place in therapy in ulcerative colitis.

scientific article

Influence of Immunogenicity on the Long-Term Efficacy of Infliximab in Crohn's Disease

scientific article

Inhibition of gelatinase B/MMP-9 does not attenuate colitis in murine models of inflammatory bowel disease

scientific article

Integrated miRNA and mRNA expression profiling in inflamed colon of patients with ulcerative colitis

scientific article

Interleukin-15 receptor α expression in inflammatory bowel disease patients before and after normalization of inflammation with infliximab

scientific article published in January 2013

Intersphincteric proctectomy with end-colostomy for anorectal Crohn's disease results in early and severe proximal colonic recurrence

scientific article

Intravenous iron therapy restores functional iron deficiency induced by infliximab

Long-Term Monitoring of Infliximab Therapy for Perianal Fistulizing Crohn's Disease by Using Magnetic Resonance Imaging

Long-Term Outcome of Patients with Ulcerative Colitis and Primary Non-response to Infliximab

scientific article

Long-term Efficacy and Safety of Stem Cell Therapy (Cx601) for Complex Perianal Fistulas in Patients With Crohn's Disease

scientific article published on 22 December 2017

Long-term outcome after infliximab for refractory ulcerative colitis

scholarly article by Marc Ferrante et al published September 2008 in Journal of Crohn's and Colitis

Long-term outcome of patients with Crohn's disease who discontinued infliximab therapy upon clinical remission

scientific article published on 3 December 2014

Long-term outcome of treatment with intravenous cyclosporin in patients with severe ulcerative colitis

scientific article published in March 2004

Low Fecal Calprotectin Correlates with Histological Remission and Mucosal Healing in Ulcerative Colitis and Colonic Crohn's Disease

scientific article published on 28 January 2016

Low TREM1 expression in whole blood predicts anti-TNF response in inflammatory bowel disease

Management of loss of response to anti-TNF drugs: Change the dose or change the drug?

article

Medical Therapy and Mucosal Healing

scientific article published on September 1, 2012

Medical management of postoperative recurrence in Crohn's disease

scientific article published on June 2004

Medical therapy for Crohn's disease strictures

scientific article published on January 2004

Medical treatment of inflammatory bowel diseases.

scientific article

Mucosal Healing and Long-term Outcomes of Patients With Inflammatory Bowel Diseases Receiving Clinic-based vs Trough Concentration-based Dosing of Infliximab

scientific article

Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment

scientific article

Mucosal gene expression of cell adhesion molecules, chemokines, and chemokine receptors in patients with inflammatory bowel disease before and after infliximab treatment.

scientific article

Mucosal healing in inflammatory bowel disease: impossible ideal or therapeutic target?

scientific article published on April 2007

Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease

scientific article published in September 2009

Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease

scientific article published on 8 October 2009

Neutralization of membrane TNF, but not soluble TNF, is crucial for the treatment of experimental colitis

scientific article published in February 2013

New serological markers in inflammatory bowel disease are associated with complicated disease behaviour

scientific article

New treatment options for inflammatory bowel diseases

scientific article published on 19 March 2018

No Change in Determining Crohn's Disease Recurrence or Need for Endoscopic or Surgical Intervention With Modification of Rutgeerts' Scoring System

scientific article published on 04 October 2018

Optimizing anti-TNF treatment in inflammatory bowel disease

scientific article published on May 2004

Optimizing biologic therapies for inflammatory bowel disease (ulcerative colitis and Crohn's disease).

scientific article published on December 2009

Optimizing biologic therapy for treatment of inflammatory bowel disease

scientific article published on July 1, 2013

Optimizing treatment of inflammatory bowel diseases with biologic agents

scientific article published on December 2008

Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial

scientific article

Outcome after proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis

scientific article published in January 2008

Outcome of pregnancy in women with inflammatory bowel disease treated with antitumor necrosis factor therapy

scientific article published on 6 January 2011

Outcome of restorative proctocolectomy with ileo-anal pouch for ulcerative colitis: effect of changes in clinical practice

scientific article published in November 2017

Perioperative Use of Vedolizumab is not Associated with Postoperative Infectious Complications in Patients with Ulcerative Colitis Undergoing Colectomy

scientific article published on 12 July 2017

Physiological basis for novel drug therapies used to treat the inflammatory bowel diseases. I. Immunology and therapeutic potential of antiadhesion molecule therapy in inflammatory bowel disease

scientific article

Post-Induction Adalimumab Concentration is Associated with Short-Term Mucosal Healing in Patients with Ulcerative Colitis

scientific article published on 11 July 2016

Postinfectious Irritable Bowel Syndrome: A Genetic Link Identified?

Practical Approaches to "Top-Down" Therapies for Crohn's Disease

scientific article published on July 2016

Predicting Outcomes to Optimize Disease Management in Inflammatory Bowel Diseases

scientific article published on 09 June 2016

Predictors of early response to infliximab in patients with ulcerative colitis

scientific article published in February 2007

Primary sclerosing cholangitis is characterised by intestinal dysbiosis independent from IBD

scientific article

Prognostic Value of Serologic and Histologic Markers on Clinical Relapse in Ulcerative Colitis Patients With Mucosal Healing

scholarly article by Talat Bessissow et al published November 2012 in The American Journal of Gastroenterology

Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease

scientific article

Rapid Test for Infliximab Drug Concentration Allows Immediate Dose Adaptation

scientific article published on 8 December 2016

Recommendations for the treatment of ulcerative colitis with infliximab: a gastroenterology expert group consensus

scientific article

Rectal non-Hodgkin's lymphoma in an infliximab treated patient with ulcerative colitis and primary sclerosing cholangitis

scientific article

Reply to Dr. Caprilli et al.'s letter

Reply to Drs. Silva and Santana's letter

scientific article published on September 16, 2012

Report of the ECCO pathogenesis workshop on anti-TNF therapy failures in inflammatory bowel diseases: Definitions, frequency and pharmacological aspects

scholarly article by Matthieu Allez et al published October 2010 in Journal of Crohn's and Colitis

Restoration of Foxp3+ Regulatory T-cell Subsets and Foxp3- Type 1 Regulatory-like T Cells in Inflammatory Bowel Diseases During Anti-tumor Necrosis Factor Therapy

scientific article

Role of biomarkers in the diagnosis of inflammatory bowel disease

Role of genetics in prediction of disease course and response to therapy

scientific article

Safety issues with biological therapies for inflammatory bowel disease

scientific article published on July 2006

Sarcoidosis-Like Lesions: Another Paradoxical Reaction to Anti-TNF Therapy?

scientific article published on 3 September 2016

Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 1: definitions and diagnosis

scientific article published on 03 October 2012

Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 2: current management

scientific article published on 03 October 2012

Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 3: special situations

scientific article published on 03 October 2012

Serum Neutrophil Gelatinase B-associated Lipocalin and Matrix Metalloproteinase-9 Complex as a Surrogate Marker for Mucosal Healing in Patients with Crohn's Disease

scientific article published on 7 September 2015

Serum S100A12 as a new marker for inflammatory bowel disease and its relationship with disease activity

Serum sickness, encephalitis and other complications of anti-cytokine therapy

scientific article published on January 2009

Specific members of the predominant gut microbiota predict pouchitis following colectomy and IPAA in UC.

scientific article published on 30 September 2015

Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease

scientific article published on 6 August 2015

Switch to adalimumab in patients with Crohn's disease controlled by maintenance infliximab: prospective randomised SWITCH trial

article by Gert Van Assche et al published 23 September 2011 in Gut

Systematic Review of Tumor Necrosis Factor Antagonists in Extraintestinal Manifestations in Inflammatory Bowel Disease

scientific article

Targeting TNF-α for the treatment of inflammatory bowel disease

scientific article

The London position statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organisation: safety

scientific article published on 16 August 2011

The Modified Mayo Endoscopic Score (MMES): A New Index for the Assessment of Extension and Severity of Endoscopic Activity in Ulcerative Colitis Patients

scientific article published on 26 June 2015

The Occurrence of Thrombosis in Inflammatory Bowel Disease Is Reflected in the Clot Lysis Profile

scientific article

The optimization of immunosuppressive and biologic cotherapies in inflammatory bowel disease

scientific article published on March 1, 2008

The role of C-reactive protein as an inflammatory marker in gastrointestinal diseases

scientific article

The role of aminosalicylates in the treatment of ulcerative colitis

scientific article published in October 2002

The role of vascular endothelial growth factor (VEGF) in inflammatory bowel disease.

scientific article

The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis

scientific article published on January 15, 2010

The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Special situations

scientific article

The use of fecal calprotectin and lactoferrin in patients with IBD. Review

scientific article published on September 2013

The use of prognostic factors in inflammatory bowel diseases

scientific article

Therapeutic Drug Monitoring of Biologics for Inflammatory Bowel Disease

scientific article published on October 21, 2011

Therapy of Metronidazole With Azathioprine to Prevent Postoperative Recurrence of Crohn's Disease: A Controlled Randomized Trial

article by Geert R. D'Haens et al published October 2008 in Gastroenterology

Transcriptomic analysis of intestinal fibrosis-associated gene expression in response to medical therapy in Crohn's disease.

scientific article

Treating beyond symptoms with a view to improving patient outcomes in inflammatory bowel diseases

scientific article

Treatment of severe steroid refractory ulcerative colitis

scientific article published on September 2008

Treatment satisfaction, preferences and perception gaps between patients and physicians in the ulcerative colitis CARES study: A real world-based study

scientific article published on 2 March 2016

Tuberculosis infection following anti-TNF therapy in inflammatory bowel disease, despite negative screening

scientific article published on 2 December 2013

Unique gene expression and MR T2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease

scientific article

Vaccination and infection prevention in inflammatory bowel disease

scientific article

Vasculitis in patients with inflammatory bowel diseases: A study of 32 patients and systematic review of the literature

scientific article published on 26 July 2015

Vedolizumab Induces Long-term Mucosal Healing in Patients With Crohn's Disease and Ulcerative Colitis

scientific article published on 24 March 2017

Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease in Patients Naïve to or Who Have Failed Tumor Necrosis Factor Antagonist Therapy

scientific article published on 7 December 2016

Vedolizumab as induction and maintenance therapy for ulcerative colitis

scientific article

Vedolizumab in refractory microscopic colitis: an international case series

scientific article published on 01 March 2019

Visualization of delayed release of compounds from pH-sensitive capsules in vitro and in vivo in a hamster model

scientific article

Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: a randomized trial

scientific article published on 8 March 2008