List of works by Lars Lindner

21-year-old patient with myocardial infarct, transient cerebral ischemia and thrombocytopenia

scientific article (publication date: March 2003)

A multi-institution study: comparison of the heating patterns of five different MR-guided deep hyperthermia systems using an anthropomorphic phantom

scientific article published on 01 January 2020

A novel immune-related gene signature predicting survival in sarcoma patients

scientific article published on 09 December 2021

A pilot trial of doxorubicin containing phosphatidyldiglycerol based thermosensitive liposomes in spontaneous feline soft tissue sarcoma.

scientific article published on 4 September 2016

Acute heart failure: when standard therapy fails--an interdisciplinary challenge

scientific article published on 06 October 2010

AraU accumulation in patients with renal insufficiency as a potential mechanism for cytarabine neurotoxicity

scientific article published on 4 October 2008

CT fluoroscopy-guided closed-tip catheter placement before regional hyperthermia treatment of soft tissue sarcomas: 5-Year experience in 35 consecutive patients

scientific article

Cancer Testis Antigens and Immunotherapy: Expression of PRAME Is Associated with Prognosis in Soft Tissue Sarcoma

scientific article published on 03 December 2020

Cationic thermosensitive liposomes: a novel dual targeted heat-triggered drug delivery approach for endothelial and tumor cells

scientific article published on 13 June 2012

Comparison of radiological and pathohistological response to neoadjuvant chemotherapy combined with regional hyperthermia (RHT) and study of response dependence on the applied thermal parameters in patients with soft tissue sarcomas (STS).

scientific article published in June 2009

Complete pathological response to neoadjuvant pemetrexed/cisplatin in combination with regional hyperthermia in a patient with sarcomatoid peritoneal mesothelioma.

scientific article published in August 2014

Crizotinib achieves long-lasting disease control in advanced papillary renal-cell carcinoma type 1 patients with MET mutations or amplification. EORTC 90101 CREATE trial

scientific article published on 14 November 2017

Crizotinib in patients with advanced, inoperable inflammatory myofibroblastic tumours with and without anaplastic lymphoma kinase gene alterations (European Organisation for Research and Treatment of Cancer 90101 CREATE): a multicentre, single-drug,

scientific article published on 12 April 2018

Dual role of hexadecylphosphocholine (miltefosine) in thermosensitive liposomes: active ingredient and mediator of drug release

scientific article published on 22 October 2007

Effective control of tumor growth through spatial and temporal control of theranostic sodium iodide symporter (NIS) gene expression using a heat-inducible gene promoter in engineered mesenchymal stem cells

scientific article published on 15 March 2020

Effectiveness of regional hyperthermia with chemotherapy for high-risk retroperitoneal and abdominal soft-tissue sarcoma after complete surgical resection: a subgroup analysis of a randomized phase-III multicenter study

scientific article published in November 2014

Effects of Surface Charge, PEGylation and Functionalization with Dipalmitoylphosphatidyldiglycerol on Liposome-Cell Interactions and Local Drug Delivery to Solid Tumors via Thermosensitive Liposomes

scientific article published on 14 June 2021

Effects of ionizing radiation in combination with Erufosine on T98G glioblastoma xenograft tumours: a study in NMRI nu/nu mice

scientific article published on 18 October 2012

Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms

scientific article published on 4 March 2010

Erufosine, a novel alkylphosphocholine, induces apoptosis in CLL through a caspase-dependent pathway.

scientific article

Evaluation of several FDG PET parameters for prediction of soft tissue tumour grade at primary diagnosis and recurrence.

scientific article published on 19 February 2015

External-beam radiation therapy combined with limb-sparing surgery in elderly patients (>70 years) with primary soft tissue sarcomas of the extremities : A retrospective analysis.

scientific article published on 22 February 2017

Factors affecting drug release from liposomes.

scientific article published on January 2010

Gemcitabine treatment of rat soft tissue sarcoma with phosphatidyldiglycerol-based thermosensitive liposomes

scientific article published on 6 March 2014

Hallmarks of hyperthermia in driving the future of clinical hyperthermia as targeted therapy: translation into clinical application.

scientific article

High IGF2 and FGFR3 are associated with tumour progression in undifferentiated pleomorphic sarcomas, but EGFR and FGFR3 mutations are a rare event.

scientific article

Hyperthermia adds to trabectedin effectiveness and thermal enhancement is associated with BRCA2 degradation and impairment of DNA homologous recombination repair

scientific article published on 02 March 2016

Hyperthermia and thermosensitive liposomes for improved delivery of chemotherapeutic drugs to solid tumors

scientific article published on 28 April 2010

Hyperthermia in soft tissue sarcoma

scientific article published on March 2011

Hyperthermia-induced targeting of thermosensitive gene carriers to tumors

scientific article published in November 2008

Ifosfamide, Carboplatin, and Etoposide (ICE) in Combination with Regional Hyperthermia as Salvage Therapy in Patients with Locally Advanced Nonmetastatic and Metastatic Soft-Tissue Sarcoma

scientific article published on 27 February 2020

Impact of chemotherapy in uterine sarcoma (UtS): review of 13 clinical trials from the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) involving advanced/metastatic UtS compared to other soft tissue sarcoma (STS) patients treated with first line ch

scientific article published on 18 May 2016

In vitro characterization of phosphatidylglyceroglycerol-based thermosensitive liposomes with encapsulated 1H MR T1-shortening gadodiamide

scientific article

In vitro stability and content release properties of phosphatidylglyceroglycerol containing thermosensitive liposomes

scientific article published on 02 June 2007

Loss of p16(INK4a) is associated with reduced patient survival in soft tissue tumours, and indicates a senescence barrier.

scientific article published on 19 April 2014

MR characterization of mild hyperthermia-induced gadodiamide release from thermosensitive liposomes in solid tumors

scientific article

Method of hyperthermia and tumor size influence effectiveness of doxorubicin release from thermosensitive liposomes in experimental tumors.

scientific article

Nanomedicine-based strategies for treatment of atherosclerosis

scientific article published on March 2014

Neo-adjuvant chemotherapy alone or with regional hyperthermia for localised high-risk soft-tissue sarcoma: a randomised phase 3 multicentre study

scientific article

Neoadjuvant or adjuvant sirolimus for malignant metastatic or locally advanced perivascular epithelioid cell tumors: two case reports

scientific article published on 7 December 2015

Novel temperature-sensitive liposomes with prolonged circulation time

scientific article published in March 2004

Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors

scientific article

PET response criteria in solid tumors predicts progression-free survival and time to local or distant progression after chemotherapy with regional hyperthermia for soft-tissue sarcoma.

scientific article published on 26 February 2015

Pharmacokinetics and biodistribution of Erufosine in nude mice--implications for combination with radiotherapy.

scientific article published on 23 October 2009

Prognostic factors for soft tissue sarcoma patients with lung metastases only who are receiving first-line chemotherapy: An exploratory, retrospective analysis of the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sa

scientific article published on 31 January 2018

Proteins and cholesterol lipid vesicles are mediators of drug release from thermosensitive liposomes.

scientific article published in July 2012

Quantification of erufosine, the first intravenously applicable alkylphosphocholine, in human plasma by isotope dilution liquid chromatography-tandem mass spectrometry using a deuterated internal standard

scientific article published on 10 May 2008

Regional hyperthermia enhances mesenchymal stem cell recruitment to tumor stroma: Implications for mesenchymal stem cell-based tumor therapy

scientific article published on 14 October 2020

Regional hyperthermia for high-risk soft tissue sarcoma treatment: present status and next questions

scientific article

Response to neoadjuvant chemotherapy combined with regional hyperthermia predicts long-term survival for adult patients with retroperitoneal and visceral high-risk soft tissue sarcomas

scientific article

Structural variation of cationic lipids: minimum requirement for improved oligonucleotide delivery into cells

scientific article

Surrogate MRI markers for hyperthermia-induced release of doxorubicin from thermosensitive liposomes in tumors

scientific article

Ten-Year Progression-Free and Overall Survival in Patients With Unresectable or Metastatic GI Stromal Tumors: Long-Term Analysis of the European Organisation for Research and Treatment of Cancer, Italian Sarcoma Group, and Australasian Gastrointesti

scientific article published on 31 March 2017

The Effect of Resection Margin on Local Recurrence and Survival in High Grade Soft Tissue Sarcoma of the Extremities: How Far Is Far Enough?

scientific article published on 08 September 2020

The membrane targeted apoptosis modulators erucylphosphocholine and erucylphosphohomocholine increase the radiation response of human glioblastoma cell lines in vitro

scientific article published on 29 March 2006

The role of hyperthermia in combined treatment in the management of soft tissue sarcoma.

scientific article published on July 2006

Thermochemotherapy in patients with extremity high-risk soft tissue sarcomas (HR-STS).

scientific article published in January 2010

Thermosensitive liposomal drug delivery systems: state of the art review.

scientific article published on 16 September 2014

Triggered content release from optimized stealth thermosensitive liposomes using mild hyperthermia

scientific article published on 13 January 2010

VEGFR2 predicts decreased patients survival in soft tissue sarcomas.

scientific article published on 21 May 2015

[Clinical impact of locoregional hyperthermia in gynecological oncology]

scientific article published on 01 October 2006

[Operative therapy of abdominal and retroperitoneal sarcoma]

scientific article published on 01 May 2014

[Principles, technology and indication of hyperthermia and part body hyperthermia]

scientific article published on 01 April 2004

[Soft-tissue sarcoma: recent developments].

scientific article published on 7 August 2012

[Systemic therapy and hyperthermia for locally advanced soft tissue sarcoma]

scientific article published on 01 May 2014

[Thermosensitive liposomes for regional hyperthermia]

scientific article published on 01 September 2003