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List of works by Claudio Bordignon

2D TR-NOESY Experiments Interrogate and Rank Ligand-Receptor Interactions in Living Human Cancer Cells

2D TR-NOESY experiments interrogate and rank ligand-receptor interactions in living human cancer cells

scientific article

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease

scientific article

A T-cell epitope encoded by a subset of HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation

scientific article published on 23 October 2003

A family of rapidly evolving genes from the sex reversal critical region in Xp21.

scientific article

Abrogation of prostaglandin E2/EP4 signaling impairs the development of rag1+ lymphoid precursors in the thymus of zebrafish embryos

scientific article published in July 2007

Absence of metabolic cross-correction in Tay-Sachs cells: implications for gene therapy

scientific article published on 28 March 2002

Acquisition of intact allogeneic human leukocyte antigen molecules by human dendritic cells.

scientific article published in June 2000

Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients

scientific article published on 24 January 2008

An approach to HIV gene therapy by transduction of multifunctional retroviral vectors in primary human T lymphocytes

scientific article published on January 1, 1997

Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs

scientific article published in October 2000

CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma

scientific article published on 9 September 2013

Cell-Surface Marking of CD34+-Restricted Phenotypes of Human Hematopoietic Progenitor Cells by Retrovirus-Mediated Gene Transfer ⬇️

scientific article published on September 1, 1997

Changes in the immune responses against human herpesvirus-8 in the disease course of posttransplant Kaposi sarcoma

scientific article

Characterization of antigenic peptides presented by HLA-B44 molecules on tumor cells expressing the gene MAGE-3.

scientific article

Clinical and immunologic responses in melanoma patients vaccinated with MAGE-A3-genetically modified lymphocytes

scientific article published on 13 December 2012

Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation

scientific article published on March 2010

Codon Optimization Leads to Functional Impairment of RD114-TR Envelope Glycoprotein

scientific article

Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs

scientific article

Coronaviridae and SARS-associated coronavirus strain HSR1.

scientific article published on March 2004

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

scientific article published in June 2002

Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells

scientific article

Corrigendum: Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs

scientific article published in Nature

De novo design of a tumor-penetrating peptide

scientific article published on 14 November 2012

Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours

Dendritic cells acquire the MAGE-3 human tumor antigen from apoptotic cells and induce a class I-restricted T cell response

scholarly article

Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer

scientific article

Erratum to “Lentiviral Vector-Mediated Gene Transfer in T Cells from Wiskott–Aldrich Syndrome Patients Leads to Functional Correction”

article

Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects

scientific article published on 11 July 2006

Expression and purification of a human, soluble Arylsulfatase A for Metachromatic Leukodystrophy enzyme replacement therapy

scientific article

Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors

scientific article published in June 1999

Expression of the MAGE gene family in primary and metastatic human breast cancer: implications for tumor antigen-specific immunotherapy.

scientific article

Extracellular NGFR Spacers Allow Efficient Tracking and Enrichment of Fully Functional CAR-T Cells Co-Expressing a Suicide Gene

scientific article published on 21 March 2018

Gene therapy

scientific article published on 01 March 1993 (PMID: 8455709)

Gene therapy in peripheral blood lymphocytes and bone marrow for ADA- immunodeficient patients

scientific article published in October 1995

Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice

scientific article

Genomic typing for patient-specific human leukocyte antigen-alleles is an efficient tool for relapse detection of high-risk hematopoietic malignancies after stem cell transplantation from alternative donors.

scientific article

Glucose-Induced Activity of Liver-Type Pyruvate Kinase Promoter in Primary Rat Hepatocytes ⬇️

scientific article published on March 1, 1998

Graft-versus-leukemia effect of HLA-haploidentical central-memory T-cells expanded with leukemic APCs and modified with a suicide gene

scientific article

Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines

scientific article published in August 2002

HLA-A*02 subtype distribution in Caucasians from northern Italy: identification of A*0220.

scientific article published in December 1996

HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

scientific article

Herpes Simplex Virus Thymidine Kinase Gene Transfer for Controlled Graft-versus-Host Disease and Graft-versus-Leukemia: Clinical Follow-up and Improved New Vectors ⬇️

scientific article published on October 10, 1998

High homogeneity of MAGE, BAGE, GAGE, Tyrosinase and Melan-A/MART-1 gene expression in clusters of multiple simultaneous metastases of human melanoma: Implications for protocol design of therapeutic antigen-specific vaccination strategies ⬇️

scientific article published on July 17, 1998

Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence

scientific article published on 20 March 2003

Human insulin production and amelioration of diabetes in mice by electrotransfer-enhanced plasmid DNA gene transfer to the skeletal muscle

scientific article published in November 2002

Human proinsulin production in primary rat hepatocytes after retroviral vector gene transfer

scientific article published on January 1999

IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes

scientific article

IL-7 receptor expression identifies suicide gene–modified allospecific CD8+ T cells capable of self-renewal and differentiation into antileukemia effectors ⬇️

scientific article published on April 29, 2011

Identification of a promiscuous T-cell epitope encoded by multiple members of the MAGE family.

scientific article

Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement

scientific article published in May 2002

Immunologic potential of donor lymphocytes expressing a suicide gene for early immune reconstitution after hematopoietic T-cell-depleted stem cell transplantation

scientific article published on 3 October 2002

Immunomodulatory Drugs in the Context of Autologous Hematopoietic Stem Cell Transplantation Associate With Reduced Pro-tumor T Cell Subsets in Multiple Myeloma

In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice

scientific article published in March 2001

Insulin-dependent diabetes mellitus and severe atopic dermatitis in a child with adenosine deaminase deficiency

scientific article published in November 1992

Isoaspartate-glycine-arginine: a new tumor vasculature-targeting motif

scientific article published in September 2008

Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy

scientific article

Lymphocytes genetically modified to express tumor antigens target DCs in vivo and induce antitumor immunity

scientific article

Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs

scientific article

Metabolic correction in oligodendrocytes derived from metachromatic leukodystrophy mouse model by using encapsulated recombinant myoblasts

scientific article

Molecular characterization of HLA class I in Colombians carrying HLA-A2: high allelic diversity and frequency of heterozygotes at the HLA-B locus

scientific article (publication date: June 1999)

Molecular purging of multiple myeloma cells by ex-vivo culture and retroviral transduction of mobilized-blood CD34+ cells

scientific article

Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy

scientific article published in August 2007

Multiple HLA-A alleles can present an immunodominant peptide of the human melanoma antigen Melan-A/MART-1 to a peptide-specific HLA-A*0201+ cytotoxic T cell line.

scientific article published on July 1996

NGR and isoDGR are separate moieties binding to different receptors

scientific article published in May 2009

NGR-TNF, a novel vascular-targeting agent, does not induce cytokine recruitment of proangiogenic bone marrow-derived cells ⬇️

scientific article published on 04 July 2013

Nonmyeloablative conditioning followed by hematopoietic cell allografting and donor lymphocyte infusions for patients with metastatic renal and breast cancer

scientific article

Optimisation of retroviral supernatant production conditions for the genetic modification of human CD34+ cells

scientific article published on May 2001

Peripheral blood lymphocytes genetically modified to express the self/tumor antigen MAGE-A3 induce antitumor immune responses in cancer patients

scientific article

Phase I Study of NGR-hTNF, a Selective Vascular Targeting Agent, in Combination with Cisplatin in Refractory Solid Tumors ⬇️

scientific article published on February 9, 2011

Phase I clinical and magnetic resonance imaging study of the vascular agent NGR-hTNF in patients with advanced cancers (European Organization for Research and Treatment of Cancer Study 16041).

scientific article published on 9 February 2010

Phase II study of asparagine-glycine-arginine-human tumor necrosis factor alpha, a selective vascular targeting agent, in previously treated patients with malignant pleural mesothelioma

scientific article published on 20 April 2010

Potential of gene therapy in bone marrow transplantation

scientific article published in January 1999

Progress and prospects: graft-versus-host disease

scientific article published on 27 May 2010

RD-MolPack technology for the constitutive production of self-inactivating lentiviral vectors pseudotyped with the nontoxic RD114-TR envelope

scientific article

RD2-MolPack-Chim3, a packaging cell line for stable production of lentiviral vectors for anti-HIV gene therapy

scientific article published on 3 August 2013

Reduced-intensity conditioning followed by allografting of hematopoietic cells can produce clinical and molecular remissions in patients with poor-risk hematologic malignancies

scientific article published in January 2002

Restoration of bacterial killing activity of human respiratory cystic fibrosis cells through cationic vector-mediated cystic fibrosis transmembrane conductance regulator gene transfer

scientific article published in August 1999

Restoration of the GM2 ganglioside metabolism in bone marrow-derived stromal cells from Tay-Sachs disease animal model

scientific article published in August 2002

Reversal of diabetes in mice by implantation of human fibroblasts genetically engineered to release mature human insulin

scientific article published on July 1999

Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors

scholarly article

Selected natural and synthetic retinoids impair CCR7- and CXCR4-dependent cell migration in vitro and in vivo

scientific article

Sequencing of a new HLA-A*32 subtype (A*3202).

scientific article published in January 1996

Stem-cell therapies for blood diseases

scientific article published in Nature

Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin

scientific article

Suicide Gene Transduced T‐cells for the Regulation of the Graft‐versus‐Leukemia Effect ⬇️

scientific article published on January 1, 1998

Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes

scientific article published on 17 November 2005

Suicide-gene-Transduced donor T-cells for controlled graft-versus-host disease and graft-versus-tumor

scientific article

Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival

scientific article published on 3 February 2015

The DAM gene family encodes a new group of tumor-specific antigens recognized by human leukocyte antigen A2-restricted cytotoxic T lymphocytes

scientific article

The IL-1/IL-1 receptor axis and tumor cell released inflammasome adaptor ASC are key regulators of TSLP secretion by cancer associated fibroblasts in pancreatic cancer

The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils

scientific article

The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies

scientific article published on 27 February 2007

The suicide gene therapy challenge: how to improve a successful gene therapy approach

scientific article published on 8 May 2007

The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms

scientific article published on July 2015

Therapeutic applications for hematopoietic stem cell gene transfer

scientific article

Transduced Fibroblasts and Metachromatic Leukodystrophy Lymphocytes Transfer Arylsulfatase A to Myelinating Glia and Deficient CellsIn Vitro ⬇️

scientific article published on September 20, 1998

Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage

scientific article

Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

scientific article

Twenty-five years of gene therapy for genetic diseases and leukemia: The road to marketing authorization of the first ex vivo gene therapies

scientific article

Various Cells Retrovirally Transduced withN-Acetylgalactosoamine-6-Sulfate Sulfatase Correct Morquio Skin FibroblastsIn Vitro ⬇️

scientific article published on November 1, 2001

Vectofusin-1 Promotes RD114-TR-Pseudotyped Lentiviral Vector Transduction of Human HSPCs and T Lymphocytes

scientific article published on 8 March 2017

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