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List of works by Claudio Bordignon

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Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy

scientific article
HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

scientific article
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

scientific article published in June 2002
Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs

scientific article
Gene therapy in peripheral blood lymphocytes and bone marrow for ADA- immunodeficient patients

scientific article published in October 1995
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer

scientific article
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy

scientific article published in August 2007
Correction of metachromatic leukodystrophy in the mouse model by transplantation of genetically modified hematopoietic stem cells

scientific article
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies

scientific article published on 27 February 2007
CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma

scientific article published on 9 September 2013
In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice

scientific article published in March 2001
Gene therapy of metachromatic leukodystrophy reverses neurological damage and deficits in mice

scientific article
Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

scientific article
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease

scientific article
IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes

scientific article
Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors

scholarly article
Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement

scientific article published in May 2002
Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines

scientific article published in August 2002
A T-cell epitope encoded by a subset of HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation

scientific article published on 23 October 2003
Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence

scientific article published on 20 March 2003
Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors

scientific article published in June 1999
Nonmyeloablative conditioning followed by hematopoietic cell allografting and donor lymphocyte infusions for patients with metastatic renal and breast cancer

scientific article
Herpes Simplex Virus Thymidine Kinase Gene Transfer for Controlled Graft-versus-Host Disease and Graft-versus-Leukemia: Clinical Follow-up and Improved New Vectors

scientific article published on October 10, 1998
The suicide gene therapy challenge: how to improve a successful gene therapy approach

scientific article published on 8 May 2007
Comparison between cationic polymers and lipids in mediating systemic gene delivery to the lungs

scientific article
Dendritic cells acquire the MAGE-3 human tumor antigen from apoptotic cells and induce a class I-restricted T cell response

scholarly article
Immunologic potential of donor lymphocytes expressing a suicide gene for early immune reconstitution after hematopoietic T-cell-depleted stem cell transplantation

scientific article published on 3 October 2002
The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils

scientific article
Phase II study of asparagine-glycine-arginine-human tumor necrosis factor alpha, a selective vascular targeting agent, in previously treated patients with malignant pleural mesothelioma

scientific article published on 20 April 2010
Reduced-intensity conditioning followed by allografting of hematopoietic cells can produce clinical and molecular remissions in patients with poor-risk hematologic malignancies

scientific article published in January 2002
Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes

scientific article published on 17 November 2005
Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs

scientific article published in October 2000
Translation of a retained intron in tyrosinase-related protein (TRP) 2 mRNA generates a new cytotoxic T lymphocyte (CTL)-defined and shared human melanoma antigen not expressed in normal cells of the melanocytic lineage

scientific article
Structural basis for the interaction of isoDGR with the RGD-binding site of alphavbeta3 integrin

scientific article
De novo design of a tumor-penetrating peptide

scientific article published on 14 November 2012
Isoaspartate-glycine-arginine: a new tumor vasculature-targeting motif

scientific article published in September 2008
Expression of the MAGE gene family in primary and metastatic human breast cancer: implications for tumor antigen-specific immunotherapy

scientific article
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects

scientific article published on 11 July 2006
Changes in the immune responses against human herpesvirus-8 in the disease course of posttransplant Kaposi sarcoma

scientific article
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation

scientific article published on March 2010
Coronaviridae and SARS-associated coronavirus strain HSR1.

scientific article published on March 2004
Reversal of diabetes in mice by implantation of human fibroblasts genetically engineered to release mature human insulin

scientific article published on July 1999
Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours

Phase I Study of NGR-hTNF, a Selective Vascular Targeting Agent, in Combination with Cisplatin in Refractory Solid Tumors

scientific article published on February 9, 2011
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients

scientific article published on 24 January 2008
IL-7 receptor expression identifies suicide gene–modified allospecific CD8+ T cells capable of self-renewal and differentiation into antileukemia effectors

scientific article published on April 29, 2011
Peripheral blood lymphocytes genetically modified to express the self/tumor antigen MAGE-A3 induce antitumor immune responses in cancer patients

scientific article
Phase I clinical and magnetic resonance imaging study of the vascular agent NGR-hTNF in patients with advanced cancers (European Organization for Research and Treatment of Cancer Study 16041).

scientific article published on 9 February 2010
Lymphocytes genetically modified to express tumor antigens target DCs in vivo and induce antitumor immunity

scientific article
Therapeutic applications for hematopoietic stem cell gene transfer

scientific article

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