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List of works by William H. Gerwick

1-Octen-3-ol, a self-stimulating oxylipin messenger, can prime and induce defense of marine alga

scientific article published on 22 January 2019

2-chloro-1,6(S*),8-tribromo-3-(8)(Z)-ochtodene: a metabolite of the tropical red seaweed ochtodes secundiramea

scientific article published on 25 July 2002

20S Proteasome as a Drug Target in Trichomonas vaginalis

scientific article published on 22 October 2019

3-(Hydroxyacetyl)indole, a plant growth regulator from the oregon red alga Prionitis lanceolata

scientific article published on 25 July 2002

5-Hydroxycyclopenicillone, a New β-Amyloid Fibrillization Inhibitor from a Sponge-Derived Fungus Trichoderma sp. HPQJ-34 ⬇️

scientific article published on 19 August 2017

A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Products

scientific article published on 21 February 2020

A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens. ⬇️

scientific article published on 27 April 2017

A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.

scientific article published on 2 November 2017

A Multi-Omics Characterization of the Natural Product Potential of Tropical Filamentous Marine Cyanobacteria

scientific article published on 06 January 2021

A concise enantioselective synthesis of the chlorosulfolipid malhamensilipin A.

scientific article published on March 2010

A novel uncultured heterotrophic bacterial associate of the cyanobacterium Moorea producens JHB

scientific article

Absolute configuration of curacin A, a novel antimitotic agent from the tropical marine cyanobacterium Lyngbya majuscula

Acetylcholinesterase inhibitors and antioxidants mining from marine fungi: bioassays, bioactivity coupled LC–MS/MS analyses and molecular networking

scientific article published in 2020

Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry

scientific article published on February 2006

Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance

scientific article published on 11 February 2022

Alkaloids from Corydalis decumbens suppress neuronal excitability in primary cultures of mouse neocortical neurons

scientific article published on 20 March 2018

Alkaloids from the Sponge Stylissa carteri Present Prospective Scaffolds for the Inhibition of Human Immunodeficiency Virus 1 (HIV-1)

scientific article

Almiramides A-C: discovery and development of a new class of leishmaniasis lead compounds ⬇️

scientific article published on May 2010

Alotamide A, a novel neuropharmacological agent from the marine cyanobacterium Lyngbya bouillonii

scientific article published on October 2009

An anti-inflammatory isoflavone from soybean inoculated with a marine fungus Aspergillus terreus C23-3

scientific article published on 20 May 2020

Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién ⬇️

scientific article published on 02 April 2019

Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate

scientific article published on 29 August 2016

Antifungal depsidone metabolites from Cordyceps dipterigena, an endophytic fungus antagonistic to the phytopathogen Gibberella fujikuroi ⬇️

scientific article published on January 28, 2012

Antileishmanial constituents of the Panamanian endophytic fungus Edenia sp. ⬇️

scientific article published on December 2008

Antillatoxin is a sodium channel activator that displays unique efficacy in heterologously expressed rNav1.2, rNav1.4 and rNav1.5 alpha subunits ⬇️

scientific article published on December 14, 2010

Antillatoxin: An Exceptionally Ichthyotoxic Cyclic Lipopeptide from the Tropical Cyanobacterium Lyngbya majuscula

scientific article published on 18 March 2005

Antimalarial linear lipopeptides from a Panamanian strain of the marine cyanobacterium Lyngbya majuscula. ⬇️

scientific article

Antimalarial peptides from marine cyanobacteria: isolation and structural elucidation of gallinamide A. ⬇️

scientific article published on January 2009

Antiparasitic and anticancer constituents of the endophytic fungus Aspergillus sp. strain F1544

scientific article published on February 1, 2012

Antitumor activity of hierridin B, a cyanobacterial secondary metabolite found in both filamentous and unicellular marine strains

scientific article (publication date: 2013)

Applying a Chemogeographic Strategy for Natural Product Discovery from the Marine Cyanobacterium Moorena bouillonii

scientific article published on 14 October 2020

Apratoxin A Shows Novel Pancreas-Targeting Activity through the Binding of Sec 61.

scientific article published on 29 March 2016

Apratoxin D, a potent cytotoxic cyclodepsipeptide from papua new guinea collections of the marine cyanobacteria Lyngbya majuscula and Lyngbya sordida

scientific article

Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel

scientific article published in May 2016

Artificial intelligence for natural product drug discovery ⬇️

scientific article from 2023

Assessment of Anabaena sp. Strain PCC 7120 as a Heterologous Expression Host for Cyanobacterial Natural Products: Production of Lyngbyatoxin A.

scientific article

Aurilides B and C, cancer cell toxins from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula

scientific article published on April 2006

Author Correction: Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research

scientific article published on 10 March 2020

Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta

scientific article

Bastimolide B, an Antimalarial 24-Membered Marine Macrolide Possessing a tert-Butyl Group.

scientific article published on 12 January 2018

Belamide A, a new antimitotic tetrapeptide from a Panamanian marine cyanobacterium

scientific article published on 12 April 2006

Bidirectional influence of sodium channel activation on NMDA receptor–dependent cerebrocortical neuron structural plasticity ⬇️

scientific article published on November 12, 2012

Bioactive new metabolites from the green alga Udotea orientalis growing on the Gorgonian coral Pseudopterogorgia rigida.

scientific article published on 22 September 2016

Biologically active new metabolites from a Florida collection of Moorea producens ⬇️

scientific article published on 18 July 2016

Biologically active secondary metabolites from marine cyanobacteria ⬇️

scientific article published on October 26, 2010

Bioprospecting Portuguese Atlantic coast cyanobacteria for bioactive secondary metabolites reveals untapped chemodiversity

article

Biosynthesis of 13R-hydroxyarachidonic acid, an unusual oxylipin from the red alga lithothamnion corallioides

scientific article published on 25 July 2002

Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module

scientific article published on 08 May 2018

Biosynthesis of the Marine Cyanobacterial Metabolite Barbamide. 1. Origin of the Trichloromethyl Group

scientific article published on 26 July 2002

Biosynthesis of the marine cyanobacterial metabolite barbamide. 2: Elucidation of the origin of the thiazole ring by application of a new GHNMBC experiment

scientific article published on 26 July 2002

Biosynthesis-assisted structural elucidation of the bartolosides, chlorinated aromatic glycolipids from cyanobacteria. ⬇️

scientific article published on 31 July 2015

Biosynthetic Pathway and Origin of the Chlorinated Methyl Group in Barbamide and Dechlorobarbamide, Metabolites from the Marine Cyanobacterium Lyngbya majuscula

scientific article published on 25 July 2002

Biosynthetic origin of natural products isolated from marine microorganism-invertebrate assemblages

scientific article

Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula

scientific article

Biosynthetically intriguing chlorinated lipophilic metabolites from geographically distant tropical marine cyanobacteria ⬇️

scientific article

Bissubvilides A and B, Cembrane-Capnosane Heterodimers from the Soft Coral Sarcophyton subviride.

scientific article published on 5 October 2016

Bouillonamide: a mixed polyketide-peptide cytotoxin from the marine cyanobacterium Moorea bouillonii ⬇️

scientific article published on 19 August 2013

Briarane diterpenes from the South China Sea gorgonian coral, Junceella gemmacea

scientific article published on 27 January 2014

Bromo-honaucin A inhibits osteoclastogenic differentiation in RAW 264.7 cells via Akt and ERK signaling pathways

scientific article published on 6 November 2015

Cannabinomimetic lipid from a marine cyanobacterium ⬇️

scientific article

Changes in secondary metabolic profiles of Microcystis aeruginosa strains in response to intraspecific interactions

scientific article (publication date: February 2016)

Characterization of Rhamnolipids Produced by an Arctic Marine Bacterium from the Pseudomonas fluorescence Group. ⬇️

scientific article published on 14 May 2018

Characterization of cyanobacterial hydrocarbon composition and distribution of biosynthetic pathways

scientific article (publication date: 2014)

Characterization of the initial enzymatic steps of barbamide biosynthesis

scientific article published on 01 June 2006

Chemical Constituents of the New Endophytic Fungus Mycosphaerella sp. nov. and Their Anti-parasitic Activity ⬇️

scientific article published on 26 March 2019

Chemical constituents of the new endophytic fungus Mycosphaerella sp. nov. and their anti-parasitic activity ⬇️

scientific article published on June 1, 2011

Chemoecological screening reveals high bioactivity in diverse culturable Portuguese marine cyanobacteria

scientific article published on 22 April 2013

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

scientific article published on 15 November 2007

Coibacins A and B: total synthesis and stereochemical revision

scientific article published on 09 January 2014

Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins ⬇️

scientific article

Coibamide A, a potent antiproliferative cyclic depsipeptide from the Panamanian marine cyanobacterium Leptolyngbya sp ⬇️

scientific article

Coibanoles, a new class of meroterpenoids produced by Pycnoporus sanguineus ⬇️

scientific article

Collection, Culturing, and Genome Analyses of Tropical Marine Filamentous Benthic Cyanobacteria

scientific article published on 27 April 2018

Combined LC-MS/MS and Molecular Networking Approach Reveals New Cyanotoxins from the 2014 Cyanobacterial Bloom in Green Lake, Seattle ⬇️

scientific article published on 14 November 2015

Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria ⬇️

scientific article

Commensal Oral Rothia mucilaginosa Produces Enterobactin, a Metal-Chelating Siderophore

scientific article published on 28 April 2020

Comparative genomics uncovers the prolific and distinctive metabolic potential of the cyanobacterial genus Moorea.

scientific article published on 6 March 2017

Conformational switch triggered by  -ketoglutarate in a halogenase of curacin A biosynthesis

scientific article

Correction to "Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp."

scientific article published on 17 July 2020

Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

scientific article published on 23 November 2018

Corrigendum to: "Alkaloids from Corydalis decumbens suppress neuronal excitability in primary cultures of mouse neocortical neurons" [Phytochemistry (2018) 150 85-92]

scientific article published on 13 June 2018

Corrigendum: Biosynthesis-Assisted Structural Elucidation of the Bartolosides, Chlorinated Aromatic Glycolipids from Cyanobacteria

scientific article published on 01 November 2016

Credneramides A and B: neuromodulatory phenethylamine and isopentylamine derivatives of a vinyl chloride-containing fatty acid from cf. Trichodesmium sp. nov. ⬇️

scientific article

Crossbyanols A-D, toxic brominated polyphenyl ethers from the Hawai'ian bloom-forming Cyanobacterium Leptolyngbya crossbyana ⬇️

scientific article published on April 2010

Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway

scientific article

Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching

scientific article

Curacins B and C, New Antimitotic Natural Products from the Marine Cyanobacterium Lyngbya majuscula

scientific article published on 11 March 2005

Cyanobacterial Polyketide Synthase Docking Domains: A Tool for Engineering Natural Product Biosynthesis

scientific article

Cyanolide A, a glycosidic macrolide with potent Molluscicidal activity from the Papua New Guinea cyanobacterium Lyngbya bouillonii

scientific article

Cymatherelactone and cymatherols A-C, polycyclic oxylipins from the marine brown alga Cymathere triplicata

scientific article published on 7 November 2011

Cytotoxic Microcolin Lipopeptides from the Marine Cyanobacterium Moorea producens

scientific article published on 30 August 2019

Cytotoxic halogenated monoterpenes from Plocamium cartilagineum.

scientific article published on 14 September 2016

Cytotoxic veraguamides, alkynyl bromide-containing cyclic depsipeptides from the marine cyanobacterium cf. Oscillatoria margaritifera. ⬇️

scientific article

DNA methyl transferase inhibiting halogenated monoterpenes from the Madagascar red marine alga Portieria hornemannii

scientific article (publication date: April 2006)

Depsipeptide companeramides from a Panamanian marine cyanobacterium associated with the coibamide producer ⬇️

scientific article

Dereplication and de novo sequencing of nonribosomal peptides

scientific article published on 13 July 2009

Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain

scientific article published on 04 October 2019

Desmethoxymajusculamide C, a cyanobacterial depsipeptide with potent cytotoxicity in both cyclic and ring-opened forms ⬇️

scientific article

Detailed analysis of (-)-palmyrolide a and some synthetic derivatives as voltage-gated sodium channel antagonists

scientific article

Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity

scientific article published on 11 July 2017

Dictyol H, a New Tricyclic Diterpenoid from the Brown Seaweed Dictyota dentata

scientific article published on 17 March 2005

Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae

scientific article

Dilophic acid a diterpenoid from the tropical brown seaweed dilophus guineensis

scientific article published on 25 July 2002

Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium cf. Symploca Species.

scientific article

Diverse secondary metabolites from a Puerto Rican collection of Lyngbyamajuscula

scientific article

Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase

scientific article

Dragocins A-D, Structurally Intriguing Cytotoxic Metabolites from a Panamanian Marine Cyanobacterium

scientific article published on 19 December 2018

Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity ⬇️

scientific article

Drug Discovery from Marine Microbes ⬇️

scientific article published on December 30, 2012

Dudawalamides A-D, Antiparasitic Cyclic Depsipeptides from the Marine Cyanobacterium Moorea producens.

scientific article

Dynamics of antibacterial activity in three species of Caribbean marine algae as a function of habitat and life history

scientific article published on 31 October 2004

Eckmaxol, a Phlorotannin Extracted from Ecklonia maxima, Produces Anti-β-amyloid Oligomer Neuroprotective Effects Possibly via Directly Acting on Glycogen Synthase Kinase 3β.

scientific article

Egregiachlorides A-C: New chlorinated oxylipins from the marine brown alga Egregia menziesii

scientific article published on 25 July 2002

Eicosanoids and other hydroxylated fatty acids from the marine alga Gracilariopsis lemaneiformis

scientific article published on 25 July 2002

Eicosanoids from the tropical red alga Murrayella periclados

scientific article published on 25 July 2002

Elegant metabolite biosynthesis

scientific article

Enantioselective divergent syntheses of several polyhalogenated Plocamium monoterpenes and evaluation of their selectivity for solid tumors.

scientific article published on 12 September 2014

Enzymatic production of (-)-indolactam V by LtxB, a cytochrome P450 monooxygenase

scientific article published in January 2010

Enzyme Inhibition by Hydroamination: Design and Mechanism of a Hybrid Carmaphycin-Syringolin Enone Proteasome Inhibitor

scientific article

Epicortical Brevetoxin Treatment Promotes Neural Repair and Functional Recovery after Ischemic Stroke

scientific article published on 21 July 2020

Evaluation of Streptomyces coelicolor A3(2) as a heterologous expression host for the cyanobacterial protein kinase C activator lyngbyatoxin A.

scientific article published in March 2012

Evaluation of the efficiency of three different solvent systems to extract triterpene saponins from roots of Panax quinquefolius using high-performance liquid chromatography

scientific article published in March 2004

Evolved diversification of a modular natural product pathway: apratoxins F and G, two cytotoxic cyclic depsipeptides from a Palmyra collection of Lyngbya bouillonii.

scientific article published in July 2010

Expanding the Described Metabolome of the Marine Cyanobacterium Moorea producens JHB through Orthogonal Natural Products Workflows ⬇️

scientific article

Expedient synthesis of α,α-dimethyl-β-hydroxy carbonyl scaffolds via Evans' aldol reaction with a tertiary enolate

scientific article published on June 2011

Exploiting adaptive laboratory evolution of Streptomyces clavuligerus for antibiotic discovery and overproduction ⬇️

scientific article

Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents

scientific article published on 15 October 2018

Five chemically rich species of tropical marine cyanobacteria of the genus Okeania gen. nov. (Oscillatoriales, Cyanoprokaryota).

scientific article

Fucoxanthin, a Marine Carotenoid, Attenuates β-Amyloid Oligomer-Induced Neurotoxicity Possibly via Regulating the PI3K/Akt and the ERK Pathways in SH-SY5Y Cells

scientific article published on 8 August 2017

GNAT-like strategy for polyketide chain initiation

scientific article

Galactolipids from the temperate red marine alga Gracilariopsis lemaneiformis

scientific article published on 25 July 2002

Gargantulide A, a complex 52-membered macrolactone showing antibacterial activity from Streptomyces sp.

scientific article published on 27 February 2015

Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula.

scientific article

Gloiosiphones A and B, Novel Metabolites from the Red Marine Alga Gloiosiphonia verticillaris

scientific article published on 17 March 2005

Heterologous Expression in <i>Anabaena</i> of the Columbamide Pathway from the Cyanobacterium <i>Moorena bouillonii</i> and Production of New Analogs

scientific article published in 2022

Heterologous Expression of Cryptomaldamide in a Cyanobacterial Host

scientific article published on 12 November 2020

Heterologous Production of 4-O-Demethylbarbamide, a Marine Cyanobacterial Natural Product ⬇️

scientific article published on November 13, 2012

High-titer heterologous production in E. coli of lyngbyatoxin, a protein kinase C activator from an uncultured marine cyanobacterium

scientific article published on 17 June 2013

Highly Convergent Total Synthesis and Assignment of Absolute Configuration of Majusculamide D, a Potent and Selective Cytotoxic Metabolite from Moorea sp

scientific article published on 23 January 2019

Hoiamide D, a marine cyanobacteria-derived inhibitor of p53/MDM2 interaction ⬇️

scientific article published on October 24, 2011

Hoiamide a, a sodium channel activator of unusual architecture from a consortium of two papua new Guinea cyanobacteria ⬇️

scientific article published on August 2009

Honaucins A−C, Potent Inhibitors of Inflammation and Bacterial Quorum Sensing: Synthetic Derivatives and Structure-Activity Relationships ⬇️

scientific article published on May 25, 2012

Hormothamnione, a novel cytotoxic styrylchromone from the marine cyanophyte grunow

scientific article published on 25 July 2002

Hydroxyalkenylresorcinols from Stylogyne turbacensis.

scientific article published on 13 July 2007

Ichthyotoxic and cytotoxic metabolites of the tropical brown alga Stypopodium zonale (Lamouroux) Papenfuss

scientific article published on 12 March 2005

Ichthyotoxic brominated diphenyl ethers from a mixed assemblage of a red alga and cyanobacterium: structure clarification and biological properties

scientific article

Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge with Inhibitory Activity against the West Nile Virus NS3 Protease

Imaging mass spectrometry of natural products

scientific article

Influence of lipid-soluble gating modifier toxins on sodium influx in neocortical neurons

scientific article

Integrated Genomic and Metabolomic Approach to the Discovery of Potential Anti-Quorum Sensing Natural Products from Microbes Associated with Marine Samples from Singapore

scientific article published on 21 January 2019

Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium ⬇️

scientific article published on 5 January 2017

Integrating mass spectrometry and genomics for cyanobacterial metabolite discovery

scientific article

Interpretation of tandem mass spectra obtained from cyclic nonribosomal peptides

scientific article published on June 2009

Involvement of JNK and caspase activation in hoiamide A-induced neurotoxicity in neocortical neurons

scientific article

Ion mobility mass spectrometry enables the efficient detection and identification of halogenated natural products from cyanobacteria with minimal sample preparation ⬇️

scientific article published on November 15, 2011

Isolation and Structure of Five Lyngbyabellin Derivatives from a Papua New Guinea Collection of the Marine Cyanobacterium Lyngbya majuscula.

scientific article published on 3 March 2006

Isolation and structure of constanolactones A and B, new cyclopropyl hydroxy-eicosanoids from the temperate red alga constantinea simplex

scientific article published on 25 July 2002

Isolation and structure of five lyngbyabellin derivatives from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula

scientific article published on 30 September 2005

Isolation of 12-(S)-hepe from the red marine alga murrayella periclados and revision of structure of an acyclic icosanoid from laurencia hybrida. Implications to the biosynthesis of the marine prostanoid hybridalactone

article by Matthew Bernart & William H Gerwick published 25 July 2002 in Tetrahedron Letters

Isolation of Polycavernoside D from a Marine Cyanobacterium

scientific article

Isolation of four new cyclic depsipeptides, antanapeptins A-D, and dolastatin 16 from a Madagascan collection of Lyngbya majuscula

scientific article published on January 2002

Isolation of swinholide A and related glycosylated derivatives from two field collections of marine cyanobacteria

scientific article published on 01 March 2005

Kalkipyrone B, a marine cyanobacterial γ-pyrone possessing cytotoxic and anti-fungal activities ⬇️

scientific article

Kalkitoxin inhibits angiogenesis, disrupts cellular hypoxic signaling, and blocks mitochondrial electron transport in tumor cells

scientific article

Ketoreductase Domain Dysfunction Expands Chemodiversity: Malyngamide Biosynthesis in the Cyanobacterium Okeania hirsuta ⬇️

scientific article published on 03 December 2018

Laucysteinamide A, a Hybrid PKS/NRPS Metabolite from a Saipan Cyanobacterium, cf. Caldora penicillata. ⬇️

scientific article

Laurencione, a heterocycle from the red alga Laurencia spectabilis

article by Matthew W Bernart et al published 25 July 2002 in Phytochemistry

Lessons from the past and charting the future of marine natural products drug discovery and chemical biology

scientific article

Linoleic acid metabolism in the red algaLithothamnion corallioides: Biosynthesis of 11(R)-hydroxy-9(Z),12(Z)-octadecadienoic acid

article by Mats Hámberg et al published 29 November 2006 in Lipids

Lipopeptides from the tropical marine cyanobacterium Symploca sp. ⬇️

scientific article published on 3 March 2014

Lophocladines, bioactive alkaloids from the red alga Lophocladia sp ⬇️

scientific article published on April 2006

Lyngbouilloside, a novel glycosidic macrolide from the marine cyanobacterium Lyngbya bouillonii

scientific article published in June 2002

Lyngbyabellins K-N from Two Palmyra Atoll Collections of the Marine Cyanobacterium Moorea bouillonii ⬇️

scientific article published on September 2012

Lyngbyatoxin biosynthesis: sequence of biosynthetic gene cluster and identification of a novel aromatic prenyltransferase

scientific article

MS/MS-Based Molecular Networking Approach for the Detection of Aplysiatoxin-Related Compounds in Environmental Marine Cyanobacteria

MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus ⬇️

scientific article published on 23 October 2013

Malyngamide 2, an Oxidized Lipopeptide with Nitric Oxide Inhibiting Activity from a Papua New Guinea Marine Cyanobacterium ⬇️

scientific article published on December 14, 2010

Malyngamide I from the tropical marine cyanobacterium Lyngbya majuscula and the probable structure revision of stylocheilamide

Malyngolide dimer, a bioactive symmetric cyclodepside from the panamanian marine cyanobacterium Lyngbya majuscula ⬇️

scientific article

Marine Natural Product Honaucin A Attenuates Inflammation by Activating the Nrf2-ARE Pathway.

scientific article published on 7 December 2017

Marine natural products as anticancer drugs

scientific article

Marine natural products as novel antioxidant prototypes

scientific article

Marine natural products as potential anti-tubercular agents

scientific article published on 14 January 2019

Medusamide A, a Panamanian Cyanobacterial Depsipeptide with Multiple β-Amino Acids.

scientific article published on 19 January 2016

MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities

scientific article published on 16 October 2019

Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair

scientific article published on 01 July 2006

Metabolic engineering of lipid catabolism increases microalgal lipid accumulation without compromising growth

scientific article (publication date: 3 December 2013)

Metamorphic enzyme assembly in polyketide diversification

scientific article

Microbiota of healthy corals are active against fungi in a light-dependent manner ⬇️

scientific article

Minimum Information about a Biosynthetic Gene cluster.

scientific article published on August 2015

Minor alkaloids from Guatteria dumetorum with antileishmanial activity

scientific article published on February 2006

Mitsoamide: A cytotoxic linear lipopeptide from the Madagascar marine cyanobacterium Geitlerinema sp. ⬇️

scientific article published on 17 April 2007

Molecular networking as a dereplication strategy

scientific article published on 11 September 2013

Molluscicidal metabolites from an assemblage of Palmyra Atoll cyanobacteria ⬇️

scientific article published on 7 April 2011

Moorea producens gen. nov., sp. nov. and Moorea bouillonii comb. nov., tropical marine cyanobacteria rich in bioactive secondary metabolites

scientific article (publication date: May 2012)

Mooreamide A: a cannabinomimetic lipid from the marine cyanobacterium Moorea bouillonii

scientific article published on 10 September 2014

Mycoleptodiscins A and B, Cytotoxic Alkaloids from the Endophytic Fungus Mycoleptodiscus sp. F0194 ⬇️

scientific article published on April 5, 2013

NPClassifier: A Deep Neural Network-Based Structural Classification Tool for Natural Products

scientific article published on 20 October 2021

NPOmix: A machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters

NPOmix: a machine learning classifier to connect mass spectrometry fragmentation data to biosynthetic gene clusters

scientific article published on 6 October 2021

Nakienones A-C and nakitriol, new cytotoxic cyclic C11 metabolites from an okinawan cyanobacterial (Synechocystis sp.) overgrowth of coral

scientific article published on 13 May 2003

Native metabolomics identifies the rivulariapeptolide family of protease inhibitors ⬇️

scientific article published in 2022

Natural Products with Potential to Treat RNA Virus Pathogens Including SARS-CoV-2

scientific article published on 22 December 2020

Natural products chemistry and taxonomy of the marine cyanobacterium Blennothrix cantharidosmum ⬇️

scientific article published on 13 August 2008

Nature's Combinatorial Biosynthesis Produces Vatiamides A-F ⬇️

scientific article published on 28 May 2019

Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis

scientific article published in 2024

Neurotoxic meroditerpenoids from the tropical marine brown alga Stypopodium flabelliforme.

scientific article

New steroids with a rearranged skeleton as (h)P300 inhibitors from the sponge Theonella swinhoei

scientific article published on 2 April 2014

New tricks from ancient algae: natural products biosynthesis in marine cyanobacteria

scientific article published on 21 March 2009

Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes

scientific article

On the Hunt for New Toxin Families Produced by a Mediterranean Strain of the Benthic Dinoflagellate Ostreopsis cf. ovata

scientific article published in 2022

On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies

scientific article

Organization, evolution, and expression analysis of the biosynthetic gene cluster for scytonemin, a cyanobacterial UV-absorbing pigment

scientific article published on 29 May 2009

Oxo-phytodienoic acid-containing galactolipids in Arabidopsis: jasmonate signaling dependence

scientific article

Oxylipin profiling of the hypersensitive response in Arabidopsis thaliana. Formation of a novel oxo-phytodienoic acid-containing galactolipid, arabidopside E.

scientific article

Pagoamide A, a Cyclic Depsipeptide Isolated from a Cultured Marine Chlorophyte, Derbesia sp., Using MS/MS-Based Molecular Networking

scientific article published on 09 January 2020

Palmyramide A, a cyclic depsipeptide from a Palmyra Atoll collection of the marine cyanobacterium Lyngbya majuscula ⬇️

scientific article

Palmyrolide A, an Unusually Stabilized Neuroactive Macrolide from Palmyra Atoll Cyanobacteria ⬇️

scientific article published on October 15, 2010

Palstimolide A: A Complex Polyhydroxy Macrolide with Antiparasitic Activity ⬇️

scientific article published on 31 March 2020

Parguerene and precarriebowmide, two classes of lipopeptides from the marine cyanobacterium Moorea producens ⬇️

scientific article published on 17 September 2013

Peyssonenynes a and B, novel enediyne oxylipins with DNA methyl transferase inhibitory activity from the red marine alga peyssonneliacaulifera

scientific article

Phylogenetic inferences reveal a large extent of novel biodiversity in chemically rich tropical marine cyanobacteria

scientific article

Phylogeny-Guided Isolation of Ethyl Tumonoate A from the Marine Cyanobacterium cf. Oscillatoria margaritifera ⬇️

scientific article published on July 13, 2011

Polyenoic fatty acid isomerase from the marine alga Ptilota filicina: protein characterization and functional expression of the cloned cDNA.

scientific article

Polyhydroxy Cyclohexanols from a Dendrodochium sp. Fungus Associated with the Sea Cucumber Holothuria nobilis Selenka

scientific article published on 21 April 2014

Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis

scientific article published on November 2009

Polyketide genes in the marine sponge Plakortis simplex: a new group of mono-modular type I polyketide synthases from sponge symbionts.

scientific article published on 25 July 2013

Potent <i>in vitro</i> anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L

scientific article published on 24 December 2020

Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L

scientific article published on 03 November 2021

Practical total syntheses of epiquinamide enantiomers

scientific article published in September 2006

Probing marine natural product defenses with DESI-imaging mass spectrometry

scientific article (publication date: 5 May 2009)

Probing the in vivo biosynthesis of scytonemin, a cyanobacterial ultraviolet radiation sunscreen, through small scale stable isotope incubation studies and MALDI-TOF mass spectrometry ⬇️

scientific article published on June 14, 2011

Ptilodene, a novel icosanoid inhibitor of 5-lifoxygenase and Na+/K+ ATPase from the red marine alga ptilota FilicinaJ. Agardh

article by Albert Lopez & William H. Gerwick published 25 July 2002 in Tetrahedron Letters

Quantitative molecular networking to profile marine cyanobacterial metabolomes

scientific article (publication date: 2014)

Relative stereochemistry determination and synthesis of the major chlorosulfolipid from Ochromonas danica.

scientific article

Reply to Skinnider and Magarvey: Rates of novel natural product discovery remain high

scientific article published on 14 July 2017

Repurposing the GNAT Fold in the Initiation of Polyketide Biosynthesis

scientific article published on 27 November 2019

Retrospective analysis of natural products provides insights for future discovery trends

scientific article

Role of bacteria in the production and degradation of Microcystis cyanopeptides.

scientific article published on 25 February 2016

Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp ⬇️

scientific article

Screening and evaluation of antiparasitic and in vitro anticancer activities of Panamanian endophytic fungi ⬇️

scientific article published on June 1, 2011

Secondary Metabolite Variation and Bioactivities of Two Marine Aspergillus Strains in Static Co-Culture Investigated by Molecular Network Analysis and Multiple Database Mining Based on LC-PDA-MS/MS

scientific article published in 2022

Secondary metabolites from marine cyanobacteria and algae inhibit LFA-1/ICAM-1 mediated cell adhesion.

scientific article published in February 2004

Semiplenamides A-G, fatty acid amides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena

scientific article published in October 2003

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

scientific article (publication date: 9 August 2016)

Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses.

scientific article

Single Cell Genome Amplification Accelerates Identification of the Apratoxin Biosynthetic Pathway from a Complex Microbial Assemblage ⬇️

scientific article published on April 12, 2011

Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research.

scientific article

Small Molecule DFPM Derivative-Activated Plant Resistance Protein Signaling in Roots Is Unaffected by EDS1 Subcellular Targeting Signal and Chemical Genetic Isolation of victr R-Protein Mutants

scientific article

Somocystinamide A, a novel cytotoxic disulfide dimer from a Fijian marine cyanobacterial mixed assemblage

scientific article published on 01 April 2002

Spatane diterpenoids from the tropical marine alga Stoechospermum marginatum (Dictyotaceae)

scientific article published on 11 March 2005

Spatane diterpenoids from the tropical marine algae Spatoglossum schmittii and Spatoglossum howleii (Dictyotaceae)

scientific article published on 11 March 2005

Special issue in honor of William Fenical, a pioneer in marine natural products discovery and drug development.

scientific article published in March 2015

Spongosine production by a Vibrio harveyi strain associated with the sponge Tectitethya crypta. ⬇️

scientific article published on 10 February 2015

Stereospecific total synthesis of somocystinamide A.

scientific article

Streptomyces artemisiae MCCB 248 isolated from Arctic fjord sediments has unique PKS and NRPS biosynthetic genes and produces potential new anticancer natural products.

scientific article

Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase

scientific article

Structural Basis of Functional Group Activation by Sulfotransferases in Complex Metabolic Pathways ⬇️

scientific article published on September 26, 2012

Structural Basis of Polyketide Synthase O-Methylation

scientific article published on 03 December 2018

Structural and synthetic investigations of tanikolide dimer, a SIRT2 selective inhibitor, and tanikolide seco-acid from the Madagascar marine cyanobacterium Lyngbya majuscula ⬇️

scientific article published on August 2009

Structure and Absolute Stereochemistry of Phormidolide, a New Toxic Metabolite from the Marine Cyanobacterium Phormidium sp. ⬇️

Structure and Absolute Stereochemistry of Phormidolide, a New Toxic Metabolite from the Marine CyanobacteriumPhormidiumsp.

scientific article published on 08 November 2002

Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly

scientific article published in June 2002

Structure and activity of DmmA, a marine haloalkane dehalogenase ⬇️

scientific article published on January 4, 2012

Structure and biosynthesis of the jamaicamides, new mixed polyketide-peptide neurotoxins from the marine cyanobacterium Lyngbya majuscula ⬇️

scientific article published on June 2004

Structure and stereochemistry of constanolactones A-G, lactonized cyclopropyl oxylipins from the red marine alga Constantinea simplex

article by Dale G. Nagle & William H. Gerwick published 12 March 2005 in Journal of Organic Chemistry

Structure of Curacin A, a Novel Antimitotic, Antiproliferative and Brine Shrimp Toxic Natural Product from the Marine Cyanobacterium Lyngbya majuscula

scientific article published on 18 March 2005

Structure revision and absolute configuration of malhamensilipin A from the freshwater chrysophyte Poterioochromonas malhamensis

scientific article

Structure, Synthesis, and Biological Properties of Kalkitoxin, a Novel Neurotoxin from the Marine CyanobacteriumLyngbyamajuscula

scientific article published in 2000

Survey of marine natural product structure revisions: a synergy of spectroscopy and chemical synthesis

scientific article published on 12 June 2011

Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp ⬇️

scientific article

Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A

scientific article published on 10 June 2020

Synergistic allelochemicals from a freshwater cyanobacterium ⬇️

scientific article

Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra

scientific article published on 23 November 2020

Tandem acyl carrier proteins in the curacin biosynthetic pathway promote consecutive multienzyme reactions with a synergistic effect

scientific article

Taveuniamides: new chlorinated toxins from a mixed assemblage of marine cyanobacteria

scientific article published on 28 June 2004

Temporal dynamics of natural product biosynthesis in marine cyanobacteria

scientific article

Terminal Alkene Formation by the Thioesterase of Curacin A Biosynthesis: STRUCTURE OF A DECARBOXYLATING THIOESTERASE

scientific article

The Chemistry, Biochemistry and Pharmacology of Marine Natural Products from Leptolyngbya, a Chemically Endowed Genus of Cyanobacteria

scientific article published on 06 October 2020

The Face of a Molecule.

scientific article published on 8 September 2017

The Hoiamides, Structurally Intriguing Neurotoxic Lipopeptides from Papua New Guinea Marine Cyanobacteria ⬇️

scientific article published on August 27, 2010

The Metabolome of a Cyanobacterial Bloom Visualized by MS/MS-Based Molecular Networking Reveals New Neurotoxic Smenamide Analogs (C, D, and E) ⬇️

scientific article published on 26 July 2018

The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide

scientific article published on 23 December 2015

The Proteasome as a Drug Target in the Metazoan Pathogen, Schistosoma mansoni

scientific article published on 12 August 2019

The Samholides, Swinholide Related Metabolites from a Marine Cyanobacterium cf. Phormidium sp. ⬇️

scientific article published on 19 February 2018

The barbamide biosynthetic gene cluster: a novel marine cyanobacterial system of mixed polyketide synthase (PKS)-non-ribosomal peptide synthetase (NRPS) origin involving an unusual trichloroleucyl starter unit

scientific article

The carmaphycins: new proteasome inhibitors exhibiting an α,β-epoxyketone warhead from a marine cyanobacterium. ⬇️

scientific article

The chemical ecology of cyanobacteria ⬇️

scientific article

The genomisotopic approach: a systematic method to isolate products of orphan biosynthetic gene clusters

scientific article published in January 2007

The guineamides, novel cyclic depsipeptides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula

scientific article

The identification and characterization of the marine natural product scytonemin as a novel antiproliferative pharmacophore

scientific article published in November 2002

The isolation and characterization of agardhilactone, a novel oxylipin from the marine red alga Agardhiella subulata

scientific article published on 26 July 2002

The marine cyanobacterial metabolite gallinamide A is a potent and selective inhibitor of human cathepsin L.

scientific article published on 23 December 2013

The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8.

scientific article

The structure elucidation of isomalyngamide K from the marine cyanobacterium Lyngbya majuscula by experimental and DFT computational methods ⬇️

scientific article published on March 15, 2011

The unique mechanistic transformations involved in the biosynthesis of modular natural products from marine cyanobacteria

scientific article published on 04 May 2010

The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research

article by James B. McAlpine et al published 13 July 2018 in Natural Product Reports

The wewakpeptins, cyclic depsipeptides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena

scientific article

Three new malyngamides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula

scientific article published on 01 January 2003

Three new malyngamides from the marine cyanobacterium Lyngbya majuscula

scientific article published on 23 April 2003

Total structure of hormothamnin A, A toxic cyclic undecapeptide from the tropical marine cyanobacterium hormothamnion enteromorphoides

scientific article published on 25 July 2002

Transcriptional analysis of the jamaicamide gene cluster from the marine cyanobacterium Lyngbya majuscula and identification of possible regulatory proteins

scientific article

Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties ⬇️

scientific article published on 28 January 2020

Two New Chamigrene Sesquiterpenoids from the Tropical Red Alga Laurencia obtusa

scientific article published on 11 March 2005

Two New Malyngamides from a MadagascanLyngbya majuscula. ⬇️

scientific article published on 26 July 2002

Two cytotoxic stereoisomers of malyngamide C, 8-epi-malyngamide C and 8-O-acetyl-8-epi-malyngamide C, from the marine cyanobacterium Lyngbya majuscula ⬇️

scientific article published on 9 August 2010

Underestimated biodiversity as a major explanation for the perceived rich secondary metabolite capacity of the cyanobacterial genus Lyngbya ⬇️

scientific article published on April 7, 2011

Unique marine derived cyanobacterial biosynthetic genes for chemical diversity

scientific article

Uprolides N, O and P from the Panamanian Octocoral Eunicea succinea.

scientific article

Venturamides A and B: antimalarial constituents of the panamanian marine Cyanobacterium Oscillatoria sp.

scientific article published on March 2007

Vidalenolone, a novel phenolic metabolite from the tropical red alga Vidalia sp.

scientific article

Viequeamide A, a Cytotoxic Member of the Kulolide Superfamily of Cyclic Depsipeptides from a Marine Button Cyanobacterium ⬇️

scientific article published on August 27, 2012

Viridamides A and B, lipodepsipeptides with antiprotozoal activity from the marine cyanobacterium Oscillatoria nigro-viridis ⬇️

scientific article published on 21 August 2008

Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging

scientific article

Weakly antimalarial flavonol arabinofuranosides from Calycolpus warszewiczianus

scientific article published on May 2006

Wewakamide A and guineamide G, cyclic depsipeptides from the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

scientific article published on September 2011

Wewakazole, a Novel Cyclic Dodecapeptide from a Papua New Guinea Lyngbya majuscula. ⬇️

scientific article published on 29 June 2005

Wewakazole, a novel cyclic dodecapeptide from a Papua New Guinea Lyngbya majuscula

scientific article published on 01 January 2003

microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data ⬇️

scientific article published in 2024

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