List of works - Étienne-Émile Baulieu

An open label trial of C-1073 (mifepristone) for psychotic major depression

scientific article published in September 2002

Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.

scientific article published in November 2002

Local synthesis and dual actions of progesterone in the nervous system: neuroprotection and myelination.

scientific article

Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension

scientific article

Novel perspectives for progesterone in hormone replacement therapy, with special reference to the nervous system

scientific article

Etifoxine improves peripheral nerve regeneration and functional recovery

scientific article published on 15 December 2008

A role for FKBP52 in Tau protein function

scientific article

Microtubule-associated protein 2 (MAP2) is a neurosteroid receptor

scholarly article

7alpha-Hydroxypregnenolone acts as a neuronal activator to stimulate locomotor activity of breeding newts by means of the dopaminergic system

scientific article

Optimal neuroprotection by erythropoietin requires elevated expression of its receptor in neurons

scientific journal article

Effect of 1-year oral administration of dehydroepiandrosterone to 60- to 80-year-old individuals on muscle function and cross-sectional area: a double-blind placebo-controlled trial.

scientific article published in March 2003

The immunophilin FKBP52 specifically binds to tubulin and prevents microtubule formation

scientific journal article

Lithium enhances remyelination of peripheral nerves

scientific article published on February 21, 2012

Identification of the Tau phosphorylation pattern that drives its aggregation

scientific article published on 7 August 2017

Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain.

scientific article published in September 2004

Pregnenolone sulfate in the brain: a controversial neurosteroid

scientific article published on 09 October 2007

A steroid hormone that extends the lifespan of Caenorhabditis elegans

scientific article published in February 2007

Steroid hormones in multiple sclerosis

scientific article

Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum

scientific article published on May 28, 2015

In vitro metabolism of dehydroepiandrosterone (DHEA) to 7alpha-hydroxy-DHEA and Delta5-androstene-3beta,17beta-diol in specific regions of the aging brain from Alzheimer's and non-demented patients.

scientific article published in April 2003

Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy

scientific article

Calcium/calmodulin kinase inhibitors and immunosuppressant macrolides rapamycin and FK506 inhibit progestin- and glucocorticosteroid receptor-mediated transcription in human breast cancer T47D cells

scientific article published on July 1998

The FKBP-associated protein FAP48 is an antiproliferative molecule and a player in T cell activation that increases IL2 synthesis

scientific article

Developmental expression of genes involved in neurosteroidogenesis: 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase in the rat brain.

scientific article

3β-Methoxy-pregnenolone (MAP4343) as an innovative therapeutic approach for depressive disorders

scientific article published on January 19, 2012

Analysis of pregnenolone and dehydroepiandrosterone in rodent brain: cholesterol autoxidation is the key.

scientific article published on 08 June 2009

Agomelatine (S20098) modulates the expression of cytoskeletal microtubular proteins, synaptic markers and BDNF in the rat hippocampus, amygdala and PFC

scientific article published on December 8, 2011

Unexpected central role of the androgen receptor in the spontaneous regeneration of myelin

scientific article published on 07 December 2016

Androgens and aging men.

scientific article

Involvement of {beta}-catenin and unusual behavior of CBP and p300 in glucocorticosteroid signaling in Schwann cells

scientific article

Hypoxia and dehydroepiandrosterone in old age: a mouse survival study

scientific article published on 18 December 2006

Age-related Purkinje cell death is steroid dependent: RORα haplo-insufficiency impairs plasma and cerebellar steroids and Purkinje cell survival

scientific article published on 11 January 2011

Decrease of the Immunophilin FKBP52 Accumulation in Human Brains of Alzheimer's Disease and FTDP-17

scientific article published on January 1, 2012

The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior

scientific article

Effects of the Synthetic Neurosteroid: 3β-Methoxypregnenolone (MAP4343) on Behavioral and Physiological Alterations Provoked by Chronic Psychosocial Stress in Tree Shrews

scientific article published on 17 October 2015

The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington's disease

scientific article

Involvement of Aryl hydrocarbon receptor in myelination and in human nerve sheath tumorigenesis.

scientific article published on 19 January 2018

Novel protective effect of mifepristone on detrimental GABAA receptor activity to immature Purkinje neurons.

scientific article

The neuroactive steroid pregnenolone sulfate stimulates the release of gonadotropin-releasing hormone from GT1-7 hypothalamic neurons, through N-methyl-D-aspartate receptors.

scientific article published on 2 March 2006

MAPREG: toward a novel approach of neuroprotection and treatment of Alzheimer's disease

scientific article published in January 2004

Treatment of experimental spinal cord injury with 3β-methoxy-pregnenolone

scientific article published on June 12, 2011

Promoter activity and gene structure of rabbit FKBP52.

scientific article published on August 2003

Caspase-cleaved Tau-D(421) is colocalized with the immunophilin FKBP52 in the autophagy-endolysosomal system of Alzheimer's disease neurons

scientific article published on 5 July 2016

Neurosteroids: non-genomic pathways in neuroplasticity and involvement in neurological diseases

scientific article published on 25 June 2018

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

Dose-dependent effect of dehydroepiandrosterone, but not of its sulphate ester, on angiogenesis

scientific article published in October 2004

Steroid receptors in various glial cell lines expression and functional studies

scientific article published on November 2002

[On "steroid aging"]

scientific article published on 01 June 2002

Steroids and Brain, a Rising Bio-Medical Domain: a Perspective.

scientific article

A β-Turn Motif in the Steroid Hormone Receptor's Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52.

scientific article published on 19 September 2016

List of works by Étienne-Émile Baulieu

An open label trial of C-1073 (mifepristone) for psychotic major depression

Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.

Local synthesis and dual actions of progesterone in the nervous system: neuroprotection and myelination.

Dehydroepiandrosterone (DHEA) prevents and reverses chronic hypoxic pulmonary hypertension

Novel perspectives for progesterone in hormone replacement therapy, with special reference to the nervous system

Etifoxine improves peripheral nerve regeneration and functional recovery

A role for FKBP52 in Tau protein function

Microtubule-associated protein 2 (MAP2) is a neurosteroid receptor

7alpha-Hydroxypregnenolone acts as a neuronal activator to stimulate locomotor activity of breeding newts by means of the dopaminergic system

Optimal neuroprotection by erythropoietin requires elevated expression of its receptor in neurons

Effect of 1-year oral administration of dehydroepiandrosterone to 60- to 80-year-old individuals on muscle function and cross-sectional area: a double-blind placebo-controlled trial.

The immunophilin FKBP52 specifically binds to tubulin and prevents microtubule formation

Lithium enhances remyelination of peripheral nerves

Identification of the Tau phosphorylation pattern that drives its aggregation

Novel lipoidal derivatives of pregnenolone and dehydroepiandrosterone and absence of their sulfated counterparts in rodent brain.

Pregnenolone sulfate in the brain: a controversial neurosteroid

A steroid hormone that extends the lifespan of Caenorhabditis elegans

Steroid hormones in multiple sclerosis

Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum

In vitro metabolism of dehydroepiandrosterone (DHEA) to 7alpha-hydroxy-DHEA and Delta5-androstene-3beta,17beta-diol in specific regions of the aging brain from Alzheimer's and non-demented patients.

Immunophilin FKBP52 induces Tau-P301L filamentous assembly in vitro and modulates its activity in a model of tauopathy

Calcium/calmodulin kinase inhibitors and immunosuppressant macrolides rapamycin and FK506 inhibit progestin- and glucocorticosteroid receptor-mediated transcription in human breast cancer T47D cells

The FKBP-associated protein FAP48 is an antiproliferative molecule and a player in T cell activation that increases IL2 synthesis

Developmental expression of genes involved in neurosteroidogenesis: 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase in the rat brain.

3β-Methoxy-pregnenolone (MAP4343) as an innovative therapeutic approach for depressive disorders

Analysis of pregnenolone and dehydroepiandrosterone in rodent brain: cholesterol autoxidation is the key.

Agomelatine (S20098) modulates the expression of cytoskeletal microtubular proteins, synaptic markers and BDNF in the rat hippocampus, amygdala and PFC

Unexpected central role of the androgen receptor in the spontaneous regeneration of myelin

Androgens and aging men.

Involvement of {beta}-catenin and unusual behavior of CBP and p300 in glucocorticosteroid signaling in Schwann cells

Hypoxia and dehydroepiandrosterone in old age: a mouse survival study

Age-related Purkinje cell death is steroid dependent: RORα haplo-insufficiency impairs plasma and cerebellar steroids and Purkinje cell survival

Decrease of the Immunophilin FKBP52 Accumulation in Human Brains of Alzheimer's Disease and FTDP-17

The FK506-binding protein FKBP52 in vitro induces aggregation of truncated Tau forms with prion-like behavior

Effects of the Synthetic Neurosteroid: 3β-Methoxypregnenolone (MAP4343) on Behavioral and Physiological Alterations Provoked by Chronic Psychosocial Stress in Tree Shrews

The stress response factor daf-16/FOXO is required for multiple compound families to prolong the function of neurons with Huntington's disease

Involvement of Aryl hydrocarbon receptor in myelination and in human nerve sheath tumorigenesis.

Novel protective effect of mifepristone on detrimental GABAA receptor activity to immature Purkinje neurons.

The neuroactive steroid pregnenolone sulfate stimulates the release of gonadotropin-releasing hormone from GT1-7 hypothalamic neurons, through N-methyl-D-aspartate receptors.

MAPREG: toward a novel approach of neuroprotection and treatment of Alzheimer's disease

Treatment of experimental spinal cord injury with 3β-methoxy-pregnenolone

Promoter activity and gene structure of rabbit FKBP52.

Caspase-cleaved Tau-D(421) is colocalized with the immunophilin FKBP52 in the autophagy-endolysosomal system of Alzheimer's disease neurons

Neurosteroids: non-genomic pathways in neuroplasticity and involvement in neurological diseases

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Dose-dependent effect of dehydroepiandrosterone, but not of its sulphate ester, on angiogenesis

Steroid receptors in various glial cell lines expression and functional studies

[On "steroid aging"]

Steroids and Brain, a Rising Bio-Medical Domain: a Perspective.

A β-Turn Motif in the Steroid Hormone Receptor's Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52.