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List of works by Yves De Koninck

A Low-Power Current-Reuse Analog Front-End for High-Density Neural Recording Implants

scientific article published in April 2018

A Neuroethics Backbone for the Evolving Canadian Brain Research Strategy

scientific article published on 01 February 2019

A Wireless Electro-Optic Headstage With a 0.13- μm CMOS Custom Integrated DWT Neural Signal Decoder for Closed-Loop Optogenetics

scientific article published on 23 July 2019

A Wireless Electro-Optic Platform for Multimodal Electrophysiology and Optogenetics in Freely Moving Rodents

scientific article

A Wireless Fiber Photometry System Based on a High-Precision CMOS Biosensor With Embedded Continuous-Time Modulation

scientific article published on 01 June 2018

A Wireless Headstage for Combined Optogenetics and Multichannel Electrophysiological Recording

scientific article published on 20 June 2016

A Wireless Optoelectronic Neuroscience Platform for Chronic Fluorescence Sensing in Freely Behaving Rodents

scientific article published on 01 July 2018

A Wireless Optogenetic Headstage with Multichannel Electrophysiological Recording Capability

scientific article published on 9 September 2015

A microprobe for parallel optical and electrical recordings from single neurons in vivo

scientific article

A multimodal micro-optrode combining field and single unit recording, multispectral detection and photolabeling capabilities ⬇️

scientific article

A simplified up-down method (SUDO) for measuring mechanical nociception in rodents using von Frey filaments

scientific article

A spinal analog of memory reconsolidation enables reversal of hyperalgesia

scientific article

ATP-Sensitive K+ channels mediate an IPSP in dorsal horn neurones elicited by sensory stimulation

Adaptive movement compensation for in vivo imaging of fast cellular dynamics within a moving tissue

scientific article

Aging causes a preferential loss of cholinergic innervation of characterized neocortical pyramidal neurons

scientific article

Allosteric modulation of metabotropic glutamate receptors by chloride ions

scientific article

Altered chloride homeostasis in neurological disorders: a new target

scientific article published on 19 December 2006

Amiloride modulation of carbon dioxide hypersensitivity and thermal nociceptive hypersensitivity induced by interference with early maternal environment

scientific article published on 3 July 2018

An E3-ligase-based method for ablating inhibitory synapses

scientific article

An ambiguous fast synapse: a new twist in the tale of two transmitters

Anisotropic light scattering from myelinated axons in the spinal cord

scientific article published on 01 January 2020

Automated method for the segmentation and morphometry of nerve fibers in large-scale CARS images of spinal cord tissue

scientific article published on 5 November 2014

BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain

scientific article (publication date: 15 December 2005)

Biophysical basis for three distinct dynamical mechanisms of action potential initiation

scientific article

Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents

scientific article published on 30 January 2017

Bridging the cleft at GABA synapses in the brain

scientific article published on December 1994

Chemokines and pain mechanisms.

scientific article published on 25 December 2008

Chloride Dysregulation through Downregulation of KCC2 Mediates Neuropathic Pain in Both Sexes

scientific article published on 01 July 2019

Chloride Regulation: A Dynamic Equilibrium Crucial for Synaptic Inhibition

scientific article published on March 2016

Chloride extrusion enhancers as novel therapeutics for neurological diseases

scientific article

Cholinergic nerve terminals establish classical synapses in the rat cerebral cortex: synaptic pattern and age-related atrophy

scientific article published in January 2001

Cortical interneuron-mediated inhibition delays the onset of amyotrophic lateral sclerosis

scientific article published on 01 March 2020

Coxsackievirus Adenovirus Receptor Loss Impairs Adult Neurogenesis, Synapse Content, and Hippocampus Plasticity.

scientific article published on September 2016

Dendritic spine viscoelasticity and soft-glassy nature: balancing dynamic remodeling with structural stability

scientific article published on 17 November 2006

Development and Implementation of a Registry of Patients Attending Multidisciplinary Pain Treatment Clinics: The Quebec Pain Registry.

scientific article published on 09 February 2017

Differential Expression of Acid - Sensing Ion Channels in Mouse Primary Afferents in Naïve and Injured Conditions

scientific article published on 19 May 2020

Differential balance of prefrontal synaptic activity in successful versus unsuccessful cognitive aging

scientific article published in January 2013

Differential chloride homeostasis in the spinal dorsal horn locally shapes synaptic metaplasticity and modality-specific sensitization

scientific article published on 07 August 2020

Differential maturation of GABA action and anion reversal potential in spinal lamina I neurons: impact of chloride extrusion capacity.

scientific article published in October 2005

Differential progression of Dark Neuron and Fluoro-Jade labelling in the rat hippocampus following pilocarpine-induced status epilepticus

scientific article

Dorsal horn neurons presynaptic to lamina I spinoparabrachial neurons revealed by transynaptic labeling

scientific article published in December 2009

Dynamics of spinal microglia repopulation following an acute depletion

scientific article published on 10 March 2016

Efficacy of synaptic inhibition depends on multiple, dynamically interacting mechanisms implicated in chloride homeostasis

scientific article

Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells

scientific article published on 08 August 2016

Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain

scientific article

Enhanced resolution in two-photon imaging using a TM(01) laser beam at a dielectric interface

scientific article

Enhancing K-Cl co-transport restores normal spinothalamic sensory coding in a neuropathic pain model

scientific article published on 24 December 2013

Enhancing KCC2 function counteracts morphine-induced hyperalgesia

scientific article published on 20 June 2017

Enhancing neuronal chloride extrusion rescues α2/α3 GABAA-mediated analgesia in neuropathic pain

scientific article published on 13 February 2020

Enkephalin-immunoreactive nociceptive neurons in the cat spinal cord

scientific article published on 01 January 1992

Epidural optogenetics for controlled analgesia

scientific article published on 9 March 2016

Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia

scientific article published on 11 September 2020

Expression of CCR2 in Both Resident and Bone Marrow-Derived Microglia Plays a Critical Role in Neuropathic Pain

scientific article published on 01 November 2007

Extended depth of field microscopy for rapid volumetric two-photon imaging

scientific article

Extended two-photon microscopy in live samples with Bessel beams: steadier focus, faster volume scans, and simpler stereoscopic imaging

scientific article

For a structured response to the psychosocial consequences of the restrictive measures imposed by the global COVID-19 health pandemic: the MAVIPAN longitudinal prospective cohort study protocol

scientific article published in 2022

Four cell types with distinctive membrane properties and morphologies in lamina I of the spinal dorsal horn of the adult rat.

scientific article published in March 2002

Gain control of firing rate by shunting inhibition: roles of synaptic noise and dendritic saturation

scholarly article

Gephyrin clusters are absent from small diameter primary afferent terminals despite the presence of GABA(A) receptors

scientific article (publication date: 11 June 2014)

Imbalance towards inhibition as a substrate of aging-associated cognitive impairment

scientific article published on 27 December 2005

Inhibitory coupling between inhibitory interneurons in the spinal cord dorsal horn

scientific article published on 12 May 2009

Integration time in a subset of spinal lamina I neurons is lengthened by sodium and calcium currents acting synergistically to prolong subthreshold depolarization.

scientific article published in May 2005

KCC2 : nouvelle cible thérapeutique pour le traitement de pathologies neurologiques

scientific article published in May 2014

Lasting potentiation of inhibition is associated with an increased number of gamma-aminobutyric acid type A receptors activated during miniature inhibitory postsynaptic currents.

scientific article published on August 1994

Live animal myelin histomorphometry of the spinal cord with video-rate multimodal nonlinear microendoscopy

scientific article published in February 2012

Live single-cell laser tag.

scientific article

Local assessment of myelin health in a multiple sclerosis mouse model using a 2D Fourier transform approach

scientific article

Loss of STEP61 couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing.

scientific article published in June 2019

Maintaining polarization in polarimetric multiphoton microscopy

scientific article published on 17 February 2015

Mechanisms of Plasticity of Inhibition in Chronic Pain Conditions

scholarly article published 5 October 2010

Microglia control neuronal network excitability via BDNF signalling

scientific article published on 05 September 2013

Microglia disrupt mesolimbic reward circuitry in chronic pain.

scientific article published on June 2015

Mild KCC2 Hypofunction Causes Inconspicuous Chloride Dysregulation that Degrades Neural Coding

scientific article published on January 2015

Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Cl⁻ homeostasis

scientific article published on 06 January 2013

Morphological and functional characterization of cholinergic interneurons in the dorsal horn of the mouse spinal cord

scientific article published in November 2011

Morphology and neurokinin 1 receptor expression of spinothalamic lamina I neurons in the rat spinal cord

scientific article published in October 2005

Native KCC2 interactome reveals PACSIN1 as a critical regulator of synaptic inhibition

scientific article published on 13 October 2017

Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine

scientific article published on 23 July 2015

Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases

scientific article published on 01 September 2020

Neutrophils mediate blood-spinal cord barrier disruption in demyelinating neuroinflammatory diseases

scientific article (publication date: September 2014)

Nonlinear interaction between shunting and adaptation controls a switch between integration and coincidence detection in pyramidal neurons

scientific article published on September 2006

Normal and abnormal coding of somatosensory stimuli causing pain

scientific article published on 28 January 2014

Optrodes for combined optogenetics and electrophysiology in live animals

scientific article published on 2 July 2015

Organization of substance P primary sensory neurons: ultrastructural and physiological correlates ⬇️

scientific article published on July 2, 1993

P2X4 receptors influence inflammasome activation after spinal cord injury

scientific article

PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and Aβ

scientific article

Peripheral vibration causes an adenosine-mediated postsynaptic inhibitory potential in dorsal horn neurons of the cat spinal cord

scientific article published in September 1992

Pharmacological enhancement of δ-subunit-containing GABA(A) receptors that generate a tonic inhibitory conductance in spinal neurons attenuates acute nociception in mice

scientific article published on 10 March 2011

Physiological roles for adenosine and ATP in synaptic transmission in the spinal dorsal horn

scientific article published on August 1993

Postnatal changes in the Rexed lamination and markers of nociceptive afferents in the superficial dorsal horn of the rat.

scientific article published in June 2008

Probing pain pathways with light

scientific article

Pyramidal neurons switch from integrators in vitro to resonators under in vivo-like conditions

scientific article published on October 2008

QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile

scientific article published on 30 May 2011

Quantification of receptor tyrosine kinase activation and transactivation by G-protein-coupled receptors using spatial intensity distribution analysis (SpIDA).

scientific article

Quantification of receptor tyrosine kinase transactivation through direct dimerization and surface density measurements in single cells.

scientific article

Quantitative analysis of substance P-immunoreactive boutons on physiologically characterized dorsal horn neurons in the cat lumbar spinal cord

scientific article published on 01 December 1996

Rapid Mechanically Controlled Rewiring of Neuronal Circuits

scientific article

Reconsolidation and the regulation of plasticity: moving beyond memory

scientific article published on 15 May 2015

Reduction of anion reversal potential subverts the inhibitory control of firing rate in spinal lamina I neurons: towards a biophysical basis for neuropathic pain

scientific article published on 13 October 2006

Remote optogenetic activation and sensitization of pain pathways in freely moving mice.

scientific article published in November 2013

Reply to The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity

scientific article published in December 2017

Resolution and contrast enhancement in laser scanning microscopy using dark beam imaging

scientific article

Resolution enhancement in confocal microscopy using Bessel-Gauss beams

scientific article published on 01 February 2017

Resolution enhancement in laser scanning microscopy with deconvolution switching laser modes (D-SLAM).

scientific article

Restoring ionotropic inhibition as an analgesic strategy

scientific article published on 27 September 2013

Revealing protein oligomerization and densities in situ using spatial intensity distribution analysis.

scientific article

Role of cation-chloride-cotransporters (CCC) in pain and hyperalgesia

scientific article

Sensory Afferents Use Different Coding Strategies for Heat and Cold

scientific article published on 01 May 2018

Sex-dependent alterations in social behaviour and cortical synaptic activity coincide at different ages in a model of Alzheimer's disease

scientific article

Sortilin gates neurotensin and BDNF signaling to control peripheral neuropathic pain

scientific article published on 19 June 2019

Spatial Intensity Distribution Analysis Reveals Abnormal Oligomerization of Proteins in Single Cells

scientific article

Spatial and temporal pattern of changes in the number of GAD65-immunoreactive inhibitory terminals in the rat superficial dorsal horn following peripheral nerve injury

scientific article

Spatial and temporal relationship between monocyte chemoattractant protein-1 expression and spinal glial activation following peripheral nerve injury

Spatial intensity distribution analysis (SpIDA): a new tool for receptor tyrosine kinase activation and transactivation quantification

scientific article

Spinal microglia are required for long-term maintenance of neuropathic pain

scientific article

Spinal neurons exhibiting a specific nociceptive response receive abundant substance P-containing synaptic contacts ⬇️

scientific article published on June 1, 1992

Striatal Neurons Expressing D1 and D2 Receptors are Morphologically Distinct and Differently Affected by Dopamine Denervation in Mice

scientific article published on 27 January 2017

Substance P and enkephalin immunoreactivities in axonal boutons presynaptic to physiologically identified dorsal horn neurons. An ultrastructural multiple-labelling study in the cat

scientific article published on 01 April 1997

Substance P released endogenously by high-intensity sensory stimulation potentiates purinergic inhibition of nociceptive dorsal horn neurons induced by peripheral vibration

article

The Canadian Brain Research Strategy: A Focus on Early Career Researchers

scientific article

The Effects of Raising Intracellular Calcium on Synaptic GABA A Receptor-channels

article

The heterogeneity in GABAA receptor-mediated IPSC kinetics reflects heterogeneity of subunit composition among inhibitory and excitatory interneurons in spinal lamina II

scientific article

Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain

scientific article

Transformation of the output of spinal lamina I neurons after nerve injury and microglia stimulation underlying neuropathic pain

scientific article

Transgenic autoinhibition of p21-activated kinase exacerbates synaptic impairments and fronto-dependent behavioral deficits in an animal model of Alzheimer's disease

scientific article

Transition to chronic pain: opportunities for novel therapeutics

scientific article published on 01 July 2018

Translational control of nociception via 4E-binding protein 1

scientific article (publication date: 18 December 2015)

Treating pathological pain: is KCC2 the key to the gate?

scientific article published in May 2013

Two-photon excitation fluorescence microscopy with a high depth of field using an axicon

scientific article published in December 2006

Two-photon laser scanning fluorescence microscopy for functional cellular imaging: Advantages and challenges or One photon is good... but two is better!

scientific article published in October 2006

Visualization of lamina I of the dorsal horn in live adult rat spinal cord slices

scientific article published in March 2000

α5GABAA Receptors Mediate Tonic Inhibition in the Spinal Cord Dorsal Horn and Contribute to the Resolution Of Hyperalgesia.

scientific article published on 28 October 2016

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