List of works by Jian-Hua Mao

53BP1 Repair Kinetics for Prediction of In Vivo Radiation Susceptibility in 15 Mouse Strains

scientific article published on 29 September 2020

A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients

scientific article published on 28 January 2013

A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice

scientific article published on 2 July 2006

A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors

scientific article

A new role of SNAI2 in postlactational involution of the mammary gland links it to luminal breast cancer development.

scientific article

A novel gene expression-based prognostic scoring system to predict survival in gastric cancer

scientific article published on 11 July 2016

A novel isoform of Homeodomain-interacting protein kinase-2 promotes YAP/TEAD transcriptional activity in NSCLC cells

scientific article published on 02 February 2021

A robust gene expression-based prognostic risk score predicts overall survival of lung adenocarcinoma patients

scientific article published on 15 December 2017

A short synthetic peptide fragment of human C2ORF40 has therapeutic potential in breast cancer

scientific article published on 30 March 2017

A subset of skin tumor modifier loci determines survival time of tumor-bearing mice.

scientific article published on December 1999

A two-stage model for childhood acute lymphoblastic leukemia: application to hereditary and nonhereditary leukemogenesis

scientific article published in January 1997

Adverse Health Effects of Thirdhand Smoke: From Cell to Animal Models

scientific article

Aggressive Mammary Cancers Lacking Lymphocytic Infiltration Arise in Irradiated Mice and Can Be Prevented by Dietary Intervention

scientific article published on 12 December 2019

Allele-specific Hras mutations and genetic alterations at tumor susceptibility loci in skin carcinomas from interspecific hybrid mice.

scientific article

Allele-specific deletions in mouse tumors identify Fbxw7 as germline modifier of tumor susceptibility

scientific article

Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer.

scientific article

An HDAC1-binding domain within FATS bridges p21 turnover to radiation-induced tumorigenesis

scientific journal article

An integrated host-microbiome response to atrazine exposure mediates toxicity in Drosophila

scientific article published on 24 November 2021

An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survival

scientific article

Analysis of lung tumor initiation and progression in transgenic mice for Cre-inducible overexpression of Cul4A gene

scientific article published on 8 June 2015

Apoptosis in cervical squamous carcinoma: predictive value for survival following radiotherapy

scientific article

Atm heterozygosity does not increase tumor susceptibility to ionizing radiation alone or in a p53 heterozygous background.

scientific article published on 4 August 2008

C2ORF40 suppresses breast cancer cell proliferation and invasion through modulating expression of M phase cell cycle genes

scientific article published on 26 April 2013

CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression.

scientific article published on 04 December 2013

CUL4A overexpression enhances lung tumor growth and sensitizes lung cancer cells to erlotinib via transcriptional regulation of EGFR.

scientific article

Cancer evolution and individual susceptibility

scientific article

Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy

scientific article

Characterization of breast cancer by array comparative genomic hybridization.

scientific article published on August 2007

Clinical and ultrasound prediction of macrosomia in diabetic pregnancy.

scientific article published on August 1996

Clinically applicable 53-Gene prognostic assay predicts chemotherapy benefit in gastric cancer: A multicenter study

scientific article published on 14 October 2020

Co-Expression Network Analysis of Fbxw7-Associated LncRNAs Reveals Their Functions in Radiation-Induced Thymic Lymphoma

Control of genomic instability and epithelial tumor development by the p53-Fbxw7/Cdc4 pathway

scientific article

Convergence of congenic mapping and allele-specific alterations in tumors for the resolution of the Skts1 skin tumor susceptibility locus

scientific article published on 19 February 2007

Crosstalk between Aurora-A and p53: frequent deletion or downregulation of Aurora-A in tumors from p53 null mice

scientific article published on February 2007

Crosstalk between Pten and Ras signaling pathways in tumor development.

scientific article

Cul4A Modulates Invasion and Metastasis of Lung Cancer Through Regulation of ANXA10.

scientific article

Cul4A is an oncogene in malignant pleural mesothelioma

scientific article

Cul4A overexpression associated with Gli1 expression in malignant pleural mesothelioma

scientific article

Deletion of the PER3 gene on chromosome 1p36 in recurrent ER-positive breast cancer

scientific article

Densely ionizing radiation acts via the microenvironment to promote aggressive Trp53-null mammary carcinomas

scientific article published on 10 October 2014

Development of a rapid and practical mutation screening assay for human lung adenocarcinoma

scientific article

Dissociation of epithelial and neuroendocrine carcinoma lineages in the transgenic adenocarcinoma of mouse prostate model of prostate cancer

scientific article

Distinct Clinical Impact and Biological Function of Angiopoietin and Angiopoietin-like Proteins in Human Breast Cancer

scientific article published in 2021

Distinct Interactions of EBP1 Isoforms with FBXW7 Elicits Different Functions in Cancer

scientific article published on 16 February 2017

Distinct luminal-type mammary carcinomas arise from orthotopic Trp53-null mammary transplantation of juvenile versus adult mice

scientific article

Diverse tumour susceptibility in Collaborative Cross mice: identification of a new mouse model for human gastric tumourigenesis

scientific article published on 06 March 2019

Drosophila Histone Demethylase KDM5 Regulates Social Behavior through Immune Control and Gut Microbiota Maintenance

scientific article published on 19 March 2019

Early exposure to thirdhand cigarette smoke affects body mass and the development of immunity in mice.

scientific article published on 03 February 2017

Elevated expression of UBE2T exhibits oncogenic properties in human prostate cancer

scientific article

Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3.

scientific article published on 15 May 2005

Erratum to: Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

scientific article published on 9 February 2017

Evaluating the prognostic significance of FBXW7 expression level in human breast cancer by a meta-analysis of transcriptional profiles

scientific article

Expression and Transcriptional Regulation of Human ATP6V1A Gene in Gastric Cancers.

scientific article

Expression profiling reveals transcriptional regulation by Fbxw7/mTOR pathway in radiation-induced mouse thymic lymphomas

scientific article published on 2 November 2015

Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma.

scientific article

FAM83 family oncogenes are broadly involved in human cancers: an integrative multi-omics approach

scientific article published on 26 October 2016

FAM83D promotes cell proliferation and motility by downregulating tumor suppressor gene FBXW7

scientific article

FAM83D promotes epithelial-mesenchymal transition, invasion and cisplatin resistance through regulating the AKT/mTOR pathway in non-small-cell lung cancer

scientific article published on 31 January 2020

FBXW7 deletion contributes to lung tumor development and confers resistance to gefitinib therapy.

scientific article published on 6 April 2018

FBXW7 negatively regulates ENO1 expression and function in colorectal cancer

scientific article

FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression

scientific article published in September 2008

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

scientific article published in December 2004

Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity

scientific article

From Mouse to Human: Cellular Morphometric Subtype Learned From Mouse Mammary Tumors Provides Prognostic Value in Human Breast Cancer

scientific article published on 01 January 2021

Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer

scientific article

Gene transcriptional networks integrate microenvironmental signals in human breast cancer

scientific article

Genetic Background Modulates lncRNA-Coordinated Tissue Response to Low Dose Ionizing Radiation.

scientific article

Genetic Susceptibility to Thirdhand Smoke induced Lung Cancer Development

article

Genetic architecture of mouse skin inflammation and tumour susceptibility

scientific article published on 11 January 2009

Genetic background influences loss of heterozygosity patterns in radiation-induced mouse thymic lymphoma

scientific article published on January 2015

Genetic differences in transcript responses to low-dose ionizing radiation identify tissue functions associated with breast cancer susceptibility

scientific article

Genetic interactions between Pten and p53 in radiation-induced lymphoma development

scientific article published in November 2003

Genetic variants of Tgfb1 act as context-dependent modifiers of mouse skin tumor susceptibility.

scholarly article

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

scientific article published on July 2016

Genome-wide detection of chromosomal imbalances in tumors using BAC microarrays

scientific article published on 01 April 2002

Genomic approaches to identification of tumour-susceptibility genes using mouse models.

scientific article

Genomic segmental polymorphisms in inbred mouse strains

scientific article published on 22 August 2004

Gremlin is overexpressed in lung adenocarcinoma and increases cell growth and proliferation in normal lung cells.

scientific article

Gut microbiome partially mediates and coordinates the effects of genetics on anxiety-like behavior in Collaborative Cross mice

scientific article published on 11 January 2021

HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis

scholarly article

HZE Radiation Non-Targeted Effects on the Microenvironment That Mediate Mammary Carcinogenesis

scientific article

Hematein, a casein kinase II inhibitor, inhibits lung cancer tumor growth in a murine xenograft model

scientific article published on 04 September 2013

Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma

scientific article published on 25 July 2011

Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human

scientific article (publication date: August 2003)

Identification of a novel 15-gene expression signature predicting overall survival of human colorectal cancer

scientific article published on 01 December 2020

Identification of genetic factors that modify motor performance and body weight using Collaborative Cross mice

scientific article

Identification of genetic loci that control mammary tumor susceptibility through the host microenvironment.

scientific article

Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library

scientific article

Identification of prognostic groups in follicular lymphoma. The Scotland and Newcastle Lymphoma Group Therapy Working Party

scientific article published on 01 May 1993

Independent genetic control of early and late stages of chemically induced skin tumors in a cross of a Japanese wild-derived inbred mouse strain, MSM/Ms

scientific article published on 28 July 2012

Influence of early life exposure, host genetics and diet on the mouse gut microbiome and metabolome.

scientific article

Inhibition of CK2α down-regulates Hedgehog/Gli signaling leading to a reduction of a stem-like side population in human lung cancer cells

scientific article

Inhibition of ERK1/2 down-regulates the Hippo/YAP signaling pathway in human NSCLC cells.

scientific article published on February 2015

Insulin requirements during pregnancy in women with type I diabetes

scientific article published on 01 February 1994

Integrative analysis of multi-omics data reveals distinct impacts of DDB1-CUL4 associated factors in human lung adenocarcinomas

scientific article

Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors

scientific article

Knockdown of Cul4A increases chemosensitivity to gemcitabine through upregulation of TGFBI in lung cancer cells

scientific article published on 2 October 2015

Knockdown of cullin 4A inhibits growth and increases chemosensitivity in lung cancer cells

scientific article published on 10 March 2016

LD78beta, a non-allelic variant of human MIP-1alpha (LD78alpha), has enhanced receptor interactions and potent HIV suppressive activity

scientific article (publication date: 18 June 1999)

Laminin signals initiate the reciprocal loop that informs breast-specific gene expression and homeostasis by activating NO, p53 and microRNAs.

scientific article published on 21 March 2018

Low-dose ionizing radiation-induced blood plasma metabolic response in a diverse genetic mouse population

scientific article published on 10 October 2012

Low-dose radiation cancer susceptibility models.

scientific article published on June 2015

Lung tumourigenesis in a conditional Cul4A transgenic mouse model.

scientific article

Macrophage prostaglandin E2 and oxidative responses to endotoxin during immunosuppression associated with anaesthesia and transfusion.

scientific article published in December 1993

Mapping segmental and sequence variations among laboratory mice using BAC array CGH.

scientific article

Mass spectrometry imaging for in situ kinetic histochemistry

scientific article published on January 2013

Meta-analysis of Aurora Kinase A (AURKA) Expression Data Reveals a Significant Correlation Between Increased AURKA Expression and Distant Metastases in Human ER-positive Breast Cancers

scientific article

MicroRNA (miR)-203 and miR-205 expression patterns identify subgroups of prognosis in cutaneous squamous cell carcinoma

scientific article

Missing heritability of complex diseases: Enlightenment by genetic variants from intermediate phenotypes

scientific article published on 31 May 2016

Multi-omics approach to infer cancer therapeutic targets on chromosome 20q across tumor types.

scientific article published on 13 July 2016

Multiple novel alternative splicing forms of FBXW7α have a translational modulatory function and show specific alteration in human cancer

scientific article

Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes

scientific article published on 21 January 2013

Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression

scientific article published on August 2004

Next-Generation Sequencing for Binary Protein-Protein Interactions

scientific article

No difference in 4-nitroquinoline induced tumorigenesis between germ-free and colonized mice

scientific article published on 22 January 2019

Novel approaches to identify low-penetrance cancer susceptibility genes using mouse models.

scientific article

Nucks1 synergizes with Trp53 to promote radiation lymphomagenesis in mice

scientific article published on 16 August 2016

Oncogenic CUL4A determines the response to thalidomide treatment in prostate cancer

scientific article published on 16 March 2012

PHENOTYPIC CHARACTERIZATION OF BREAST INVASIVE CARCINOMA VIA TRANSFERABLE TISSUE MORPHOMETRIC PATTERNS LEARNED FROM GLIOBLASTOMA MULTIFORME.

scientific article published on April 2016

PR-Set7 is Degraded in a Conditional Cul4A Transgenic Mouse Model of Lung Cancer.

scientific article published in June 2015

Pathophysiological Integration of Metabolic Reprogramming in Breast Cancer

scientific article published in 2022

Polymorphic genetic control of tumor invasion in a mouse model of pancreatic neuroendocrine carcinogenesis ⬇️

scientific article published on September 20, 2010

Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7

scientific article

Prognostic significance of FAM83D gene expression across human cancer types

scientific article published on 15 December 2015

Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer.

scientific article

Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice

scientific article published on 17 January 2007

Prospective study reveals a microbiome signature that predicts the occurrence of post-operative enterocolitis in Hirschsprung disease (HSCR) patients

scientific article published on 16 January 2020

Ptch1 overexpression drives skin carcinogenesis and developmental defects in K14Ptch(FVB) mice

scientific article published on 6 December 2012

Pten regulates Aurora-A and cooperates with Fbxw7 in modulating radiation-induced tumor development.

scientific article

RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings

scientific article

Rapamycin inhibits FBXW7 loss-induced epithelial-mesenchymal transition and cancer stem cell-like characteristics in colorectal cancer cells

scientific article published on 2 April 2013

Revisiting the impact of age and molecular subtype on overall survival after radiotherapy in breast cancer patients

scientific article published on 3 October 2017

Rewiring of human lung cell lineage and mitotic networks in lung adenocarcinomas.

scientific article published on January 2013

Sequence divergence of Mus spretus and Mus musculus across a skin cancer susceptibility locus

scientific article

Sequential mutations in Notch1, Fbxw7, and Tp53 in radiation-induced mouse thymic lymphomas

scientific article published on 23 November 2011

Short-term early exposure to thirdhand cigarette smoke increases lung cancer incidence in mice

scientific article published on 12 February 2018

Simulated space radiation-induced mutants in the mouse kidney display widespread genomic change

scientific article

Simultaneous Exposure of Cultured Human Lymphoblastic Cells to Simulated Microgravity and Radiation Increases Chromosome Aberrations

scientific article published on 10 September 2020

Stochastic modelling of tumorigenesis in p53 deficient mice.

scientific article published on January 1998

Successful application of a previously derived prognostic index in the analysis of a randomised trial of 281 patients with high grade non-Hodgkin's lymphoma (HIGNHL)

scientific article published on 01 December 1993

Supplementary data for the biological age linked to oxidative stress modifies breast cancer aggressiveness.

scientific article published on 3 April 2018

Systematic Analysis of Impact of Sampling Regions and Storage Methods on Fecal Gut Microbiome and Metabolome Profiles

scientific article published on 08 January 2020

Temporal mTOR inhibition protects Fbxw7-deficient mice from radiation-induced tumor development.

scientific article published on February 2013

The Trp53 delta proline (Trp53ΔP) mouse exhibits increased genome instability and susceptibility to radiation-induced, but not spontaneous, tumor development

scientific article published on 27 August 2015

The biological age linked to oxidative stress modifies breast cancer aggressiveness.

scientific article published on 14 March 2018

The component formula of Salvia miltiorrhiza and Panax ginseng induces apoptosis and inhibits cell invasion and migration through targeting PTEN in lung cancer cells.

scientific article published on 28 September 2017

The effect of tissue-specific growth patterns of target stem cells on the spectrum of tumours resulting from multistage tumorigenesis.

scientific article published in May 2001

The expression of Dishevelled-3 and glutamine metabolism in malignant pleural mesothelioma

scientific article

The prostate cancer-up-regulated long noncoding RNA PlncRNA-1 modulates apoptosis and proliferation through reciprocal regulation of androgen receptor

scientific article published on 20 January 2012

Thirdhand Smoke: New Evidence, Challenges, and Future Directions

scientific article published on 21 December 2016

Tobacco toxins deposited on surfaces (third hand smoke) impair wound healing

scientific article

Transgenic mice for cre-inducible overexpression of the Cul4A gene.

scientific article

Tumor suppressive microRNA-424 inhibits osteosarcoma cell migration and invasion via targeting fatty acid synthase

scientific article

Unraveling heterogeneous susceptibility and the evolution of breast cancer using a systems biology approach

scientific article

Unsupervised Transfer Learning via Multi-Scale Convolutional Sparse Coding for Biomedical Applications

scientific article published on 23 January 2017

Urethral stricture and urethritis in men in Scotland.

scientific article

[Thirdhand smoke: current research status and future prospects]

scientific article published on 01 April 2015

miR-1204 targets VDR to promotes epithelial-mesenchymal transition and metastasis in breast cancer.

scientific article published on 20 March 2018

p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo.

scientific article published in August 2005

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