List of works - Laurie T. Krug

A codon-shuffling method to prevent reversion during production of replication-defective herpesvirus stocks: Implications for herpesvirus vaccines.

scientific article published on 13 March 2017

A gammaherpesvirus 68 gene 50 null mutant establishes long-term latency in the lung but fails to vaccinate against a wild-type virus challenge.

scientific article

A gammaherpesvirus-secreted activator of Vbeta4+ CD8+ T cells regulates chronic infection and immunopathology

scientific article published on 10 March 2008

Ablation of STAT3 in the B Cell Compartment Restricts Gammaherpesvirus Latency In Vivo

scientific article published on 02 August 2016

Absence of the uracil DNA glycosylase of murine gammaherpesvirus 68 impairs replication and delays the establishment of latency in vivo

scientific article

Combinatorial Loss of the Enzymatic Activities of Viral Uracil-DNA Glycosylase and Viral dUTPase Impairs Murine Gammaherpesvirus Pathogenesis and Leads to Increased Recombination-Based Deletion in the Viral Genome

scientific article published on 30 October 2018

Complexities of gammaherpesvirus transcription revealed by microarrays and RNAseq

scientific article published on 16 May 2013

Dangerous Liaisons: Gammaherpesvirus Subversion of the Immunoglobulin Repertoire

scientific article published on 23 July 2020

Differences in DNA Binding Specificity among Roseolovirus Origin Binding Proteins

scientific article published on 01 September 2001

Editorial overview: Roseoloviruses: stopping to smell the roses--the Roseoloviruses have come of age as human pathogens

scientific article published on 17 November 2014

Enhanced response of T cells from murine gammaherpesvirus 68-infected mice lacking the suppressor of T cell receptor signaling molecules Sts-1 and Sts-2

scientific article

Gammaherpesviral gene expression and virion composition are broadly controlled by accelerated mRNA degradation

scientific article published on 16 January 2014

Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3.

scientific article

Impact of Adenovirus E4-ORF3 Oligomerization and Protein Localization on Cellular Gene Expression

scientific article published on 13 May 2015

Inhibition of NF-kappaB activation in vivo impairs establishment of gammaherpesvirus latency

scientific article

Inhibition of NF-kappaB signaling reduces virus load and gammaherpesvirus-induced pulmonary fibrosis

scientific article

Inhibition of infection and replication of human herpesvirus 8 in microvascular endothelial cells by alpha interferon and phosphonoformic acid

scientific article published on August 2004

Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host

scientific article

Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1β Production upon Extrinsic Stimulation in Culture

scientific article published on 8 April 2015

Mutational pressure by host APOBEC3s more strongly affects genes expressed early in the lytic phase of herpes simplex virus-1 (HSV-1) and human polyomavirus (HPyV) infection

scientific article published on 30 April 2021

NF-kappaB p50 plays distinct roles in the establishment and control of murine gammaherpesvirus 68 latency

scientific article published on 04 March 2009

RTA Occupancy of the Origin of Lytic Replication during Murine Gammaherpesvirus 68 Reactivation from B Cell Latency.

scientific article published on 16 February 2017

Role of endoplasmic reticulum stress in age-related susceptibility to lung fibrosis

scientific article

Roseolovirus molecular biology: recent advances

scientific article

Roseoloviruses: unmet needs and research priorities: perspective.

scientific article

Sequence requirements for interaction of human herpesvirus 7 origin binding protein with the origin of lytic replication.

scientific article published on April 2001

Short duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interferon in BCBL-1 cells.

scientific article

The absence of M1 leads to increased establishment of murine gammaherpesvirus 68 latency in IgD-negative B cells

scientific article published on 9 January 2013

The replication and transcription activator of murine gammaherpesvirus 68 cooperatively enhances cytokine-activated, STAT3-mediated gene expression.

scientific article

The targeting of primary effusion lymphoma cells for apoptosis by inducing lytic replication of human herpesvirus 8 while blocking virus production

scientific article published in February 2005

Tiled microarray identification of novel viral transcript structures and distinct transcriptional profiles during two modes of productive murine gammaherpesvirus 68 infection

scientific article published on 8 February 2012

U94, the human herpesvirus 6 homolog of the parvovirus nonstructural gene, is highly conserved among isolates and is expressed at low mRNA levels as a spliced transcript.

scientific article published on March 2000

Variable methylation of the Epstein-Barr virus Wp EBNA gene promoter in B-lymphoblastoid cell lines

scientific article published on December 2004

Viral FGARAT ORF75A promotes early events in lytic infection and gammaherpesvirus pathogenesis in mice.

scientific article published in February 2018

List of works by Laurie T. Krug

A codon-shuffling method to prevent reversion during production of replication-defective herpesvirus stocks: Implications for herpesvirus vaccines.

A gammaherpesvirus 68 gene 50 null mutant establishes long-term latency in the lung but fails to vaccinate against a wild-type virus challenge.

A gammaherpesvirus-secreted activator of Vbeta4+ CD8+ T cells regulates chronic infection and immunopathology

Ablation of STAT3 in the B Cell Compartment Restricts Gammaherpesvirus Latency In Vivo

Absence of the uracil DNA glycosylase of murine gammaherpesvirus 68 impairs replication and delays the establishment of latency in vivo

Combinatorial Loss of the Enzymatic Activities of Viral Uracil-DNA Glycosylase and Viral dUTPase Impairs Murine Gammaherpesvirus Pathogenesis and Leads to Increased Recombination-Based Deletion in the Viral Genome

Complexities of gammaherpesvirus transcription revealed by microarrays and RNAseq

Dangerous Liaisons: Gammaherpesvirus Subversion of the Immunoglobulin Repertoire

Differences in DNA Binding Specificity among Roseolovirus Origin Binding Proteins

Editorial overview: Roseoloviruses: stopping to smell the roses--the Roseoloviruses have come of age as human pathogens

Enhanced response of T cells from murine gammaherpesvirus 68-infected mice lacking the suppressor of T cell receptor signaling molecules Sts-1 and Sts-2

Gammaherpesviral gene expression and virion composition are broadly controlled by accelerated mRNA degradation

Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3.

Impact of Adenovirus E4-ORF3 Oligomerization and Protein Localization on Cellular Gene Expression

Inhibition of NF-kappaB activation in vivo impairs establishment of gammaherpesvirus latency

Inhibition of NF-kappaB signaling reduces virus load and gammaherpesvirus-induced pulmonary fibrosis

Inhibition of infection and replication of human herpesvirus 8 in microvascular endothelial cells by alpha interferon and phosphonoformic acid

Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host

Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1β Production upon Extrinsic Stimulation in Culture

Mutational pressure by host APOBEC3s more strongly affects genes expressed early in the lytic phase of herpes simplex virus-1 (HSV-1) and human polyomavirus (HPyV) infection

NF-kappaB p50 plays distinct roles in the establishment and control of murine gammaherpesvirus 68 latency

RTA Occupancy of the Origin of Lytic Replication during Murine Gammaherpesvirus 68 Reactivation from B Cell Latency.

Role of endoplasmic reticulum stress in age-related susceptibility to lung fibrosis

Roseolovirus molecular biology: recent advances

Roseoloviruses: unmet needs and research priorities: perspective.

Sequence requirements for interaction of human herpesvirus 7 origin binding protein with the origin of lytic replication.

Short duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interferon in BCBL-1 cells.

The absence of M1 leads to increased establishment of murine gammaherpesvirus 68 latency in IgD-negative B cells

The replication and transcription activator of murine gammaherpesvirus 68 cooperatively enhances cytokine-activated, STAT3-mediated gene expression.

The targeting of primary effusion lymphoma cells for apoptosis by inducing lytic replication of human herpesvirus 8 while blocking virus production

Tiled microarray identification of novel viral transcript structures and distinct transcriptional profiles during two modes of productive murine gammaherpesvirus 68 infection

U94, the human herpesvirus 6 homolog of the parvovirus nonstructural gene, is highly conserved among isolates and is expressed at low mRNA levels as a spliced transcript.

Variable methylation of the Epstein-Barr virus Wp EBNA gene promoter in B-lymphoblastoid cell lines

Viral FGARAT ORF75A promotes early events in lytic infection and gammaherpesvirus pathogenesis in mice.