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List of works by William Vainchenker

A 93-kDa glycoprotein expressed on human cultured monocytes and dendritic reticulum cells defined by an anti-K562 monoclonal antibody

scientific article published on 01 December 1986

A CALR mutation preceding BCR-ABL1 in an atypical myeloproliferative neoplasm

scientific article

A JAK2 mutation in myeloproliferative disorders: pathogenesis and therapeutic and scientific prospects.

scientific article

A common bipotent progenitor generates the erythroid and megakaryocyte lineages in embryonic stem cell-derived primitive hematopoiesis.

scientific article

A defect in hematopoietic stem cell migration explains the nonrandom X-chromosome inactivation in carriers of Wiskott-Aldrich syndrome

scientific article published in May 2003

A gamma and G gamma globin chain synthesis in BFU-E colonies from adult, newborn, and fetal subjects and from thalassemic patients

scientific article published on 01 November 1980

A lentiviral vector encoding the human Wiskott-Aldrich syndrome protein corrects immune and cytoskeletal defects in WASP knockout mice.

scientific article

A major role of TGF-beta1 in the homing capacities of murine hematopoietic stem cell/progenitors

scientific article published on 20 May 2010

A monoclonal antibody against an erythrocyte ontogenic antigen identifies fetal and adult erythroid progenitors

scientific article published on 01 January 1986

A murine stromal cell line allows the proliferation of very primitive human CD34++/CD38- progenitor cells in long-term cultures and semisolid assays ⬇️

scientific article published on June 1, 1993

A new c-kit mutation in a case of aggressive mast cell disease

scientific article published on 01 February 1997

A new congenital dysmegakaryopoietic thrombocytopenia (Paris-Trousseau) associated with giant platelet alpha-granules and chromosome 11 deletion at 11q23.

scientific article

A new efficient tool for non-invasive diagnosis of fetomaternal platelet antigen incompatibility

scientific article published on 07 April 2020

A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene

scientific article

A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the alphaIIbbeta3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia

scientific article

A p53-JAK-STAT connection involved in myeloproliferative neoplasm pathogenesis and progression to secondary acute myeloid leukemia

scientific article published on 03 June 2020

A partial down-regulation of WASP is sufficient to inhibit podosome formation in dendritic cells

scientific article published on 15 December 2005

A senescence-like cell-cycle arrest occurs during megakaryocytic maturation: implications for physiological and pathological megakaryocytic proliferation

scientific article

A unique activating mutation in JAK2 (V617F) is at the origin of polycythemia vera and allows a new classification of myeloproliferative diseases

scientific article published in January 2005

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

scientific article (publication date: 28 April 2005)

ATG2B and GSKIP: 2 new genes predisposing to myeloid malignancies

scientific article published on 29 October 2015

Absence of erythroblastic islands in plasma clot culture and their possible reconstitution after clot lysis

scientific article published on 01 August 1979

Absence of mutations in the HoxA10, HoxA11 and HoxD11 nucleotide coding sequences in thrombocytopenia with absent radius syndrome

scientific article (publication date: February 2002)

Acceleration of the hemoglobin switch in cultures in neonate erythroid precursors by adult cells

scientific article published on 01 September 1980

Acquired TET2 mutation in one patient with familial platelet disorder with predisposition to AML led to the development of pre-leukaemic clone resulting in T2-ALL and AML-M0

scientific article

Acquired initiating mutations in early hematopoietic cells of CLL patients

scientific article

Activating mutations in human acute megakaryoblastic leukemia.

scientific article

Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes.

scientific article

Adenoviral supply of active transforming growth factor-beta1 (TGF-beta1) did not prevent lethality in transforming growth factor-beta1-knockout embryos

scientific article published on 01 October 2001

Adenoviral-mediated TGF-beta1 inhibition in a mouse model of myelofibrosis inhibit bone marrow fibrosis development

article

Alterations of NFIA in chronic malignant myeloid diseases

scientific article published on 28 August 2008

An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia

scientific article published on 20 July 2009

An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor. ⬇️

scientific article published on 25 October 2005

An incomplete trafficking defect to the cell-surface leads to paradoxical thrombocytosis for human and murine MPL P106L.

scientific article published on 10 November 2016

Analysis of the ten-eleven translocation 2 (TET2) gene in familial myeloproliferative neoplasms

scientific article published on 29 June 2009

Antiviral agent Cidofovir restores p53 function and enhances the radiosensitivity in HPV-associated cancers.

scientific article published on April 2002

Apoptosis regulation in tetraploid cancer cells

scientific article

Applying ecological and evolutionary theory to cancer: a long and winding road ⬇️

scientific article published on 16 November 2012

Aurora B is dispensable for megakaryocyte polyploidization, but contributes to the endomitotic process.

scientific article published on 14 June 2010

Autocrine stimulation by erythropoietin (Epo) requires Epo secretion.

scientific article published on October 1994

Autocrine stimulation by erythropoietin and autonomous growth of human erythroid leukemic cells in vitro

scientific article

Autonomous megakaryocyte growth in essential thrombocythemia and idiopathic myelofibrosis is not related to a c-mpl mutation or to an autocrine stimulation by Mpl-L.

scientific article published on January 1999

BCR-ABL Fails to Inhibit Apoptosis in U937 Myelomonocytic Cells Expressing a Carboxyl-Terminal Truncated Stat5 ⬇️

scientific article published on July 1, 2001

BCR-ABL activates STAT3 via JAK and MEK pathways in human cells

scientific article published on 01 July 2006

Beta O-thalassemia/Hb E association. Hemoglobin synthesis in blood reticulocytes and bone marrow cells fractionated by density gradient and in blood erythroid colonies in culture

scientific article published on 01 January 1980

Beta-thalassemia and sickle cell disease in culture of early erythroid precursors: hemoglobin synthesis and ultrastructural study

scientific article published on 01 January 1981

Biological effects induced by variable levels of BCR-ABL protein in the pluripotent hematopoietic cell line UT-7.

scientific article

Biosynthesis of major platelet proteins in human blood platelets.

scientific article

CCND2 mutations are infrequent events in BCR-ABL1 negative myeloproliferative neoplasm patients

scientific article published on 15 May 2020

CK2: a key regulator of thrombopoiesis.

scientific article

CXCL12/CXCR4 pathway is activated by oncogenic JAK2 in a PI3K-dependent manner

scientific article published on 22 July 2016

CXCR4 inhibitors selectively eliminate CXCR4-expressing human acute myeloid leukemia cells in NOG mouse model.

scientific article

CXCR4/CXCL12 axis counteracts hematopoietic stem cell exhaustion through selective protection against oxidative stress

scientific article published on 25 November 2016

Calreticulin del52 and ins5 knock-in mice recapitulate different myeloproliferative phenotypes observed in patients with MPN

scientific article published on 28 September 2020

Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants

scientific article published on 22 March 2019

Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis

scientific article published on 25 November 2015

Carboxyl-terminal-dependent recruitment of nonmuscle myosin II to megakaryocyte contractile ring during polyploidization

scientific article

Caspase-activated ROCK-1 allows erythroblast terminal maturation independently of cytokine-induced Rho signaling.

scientific article published on 12 November 2010

Cellular and molecular mechanisms of haemoglobin switching in man.

scientific article

Cellular regulation of i and I antigen expressions in human erythroblasts grown in vitro

scientific article published on 01 January 1981

Change in i-antigen expression of erythrocytes during in vivo aging

scientific article published on 01 June 1981

Characterization of hematopoietic progenitors from human yolk sacs and embryos.

scientific article

Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models

scientific article

Clonal architecture of chronic myelomonocytic leukemias

scientific article published on 14 January 2013

Clonal expression of the Tn antigen in erythroid and granulocyte colonies and its application to determination of the clonality of the human megakaryocyte colony assay.

scientific article published on May 1982

Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily

scientific article (publication date: September 2000)

Combination treatment for myeloproliferative neoplasms using JAK and pan-class I PI3K inhibitors

scientific article

Comparative patterns of i-antigen expression, F-cell frequency and Hb A2 level in acute myeloid leukemia and in acute lymphoid leukemia

scientific article published on 01 January 1981

Compared effects of Mpl ligand and other cytokines on human MK differentiation

scientific article published on 01 January 1998

Concise Review: Induced Pluripotent Stem Cells as New Model Systems in Oncology

scientific article

Concomitant germ-line RUNX1 and acquired ASXL1 mutations in a T-cell acute lymphoblastic leukemia.

scientific article published on 28 June 2013

Congenital dyserythropoietic anaemia type I: absence of clonal expression in the nuclear abnormalities of cultured erythroblasts

scientific article published on 01 September 1980

Congenital dyserythropoietic anemia type III. studies on erythroid differentiation of blood erythroid progenitor cells (BFUE) in vitro

scientific article published on 01 September 1980

Constitutive JunB expression, associated with the JAK2 V617F mutation, stimulates proliferation of the erythroid lineage.

scientific article

Constitutive activation of STAT5 and Bcl-xL overexpression can induce endogenous erythroid colony formation in human primary cells

scientific article published on 09 May 2006

Constitutive and specific activation of STAT3 by BCR-ABL in embryonic stem cells.

scientific article

Constitutive expression of GATA-1 interferes with the cell-cycle regulation.

scientific article published on May 1996

Constitutive expression of Mpl ligand transcripts during thrombocytopenia or thrombocytosis.

scientific article

Critical role of the HDAC6-cortactin axis in human megakaryocyte maturation leading to a proplatelet-formation defect.

scientific article published on 27 November 2017

Cytogenetic study of myeloid and erythroid colonies in chronic myeloid leukaemia with stable Ph1 mosaicism.

scientific article

Defective endomitosis during megakaryopoiesis leads to thrombocytopenia in Fanca-/- mice

scientific article

Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment

scientific article

Description of a knock-in mouse model of JAK2V617F MPN emerging from a minority of mutated hematopoietic stem cells

scientific article published on 01 December 2019

Detection of JAK2 V617F as a first intention diagnostic test for erythrocytosis.

scientific article

Developmental changes in human megakaryocyte ploidy.

scientific article published in February 1991

Developmental changes in human megakaryopoiesis.

scientific article published in September 2013

Developmentally regulated expression of a 78 kDa erythroblast membrane glycoprotein immunologically related to the platelet thrombospondin receptor

scientific article published on September 1989

Diagnosis of megakaryoblastic leukemias.

scientific article published on January 1983

Different impact of calreticulin mutations on human hematopoiesis in myeloproliferative neoplasms

scientific article published on 22 June 2020

Differential association of calreticulin type 1 and type 2 mutations with myelofibrosis and essential thrombocytemia: relevance for disease evolution

scientific article published on 12 September 2014

Differential regulation of actin stress fiber assembly and proplatelet formation by alpha2beta1 integrin and GPVI in human megakaryocytes

scientific article published on 20 July 2004

Differential signalling of NH2-terminal flag-labelled thrombopoietin receptor activated by TPO or anti-FLAG antibodies.

scientific article published on March 2004

Differentiation of human megakaryocytes in culture starting from the primordial circulating cells in the newborn

scientific article published on July 17, 1978

Disappearance of Hb F and i antigen during the first year of life

scientific article published on 01 January 1980

Disrupted filamin A/αβ interaction induces macrothrombocytopenia by increasing RhoA activity

scientific article published on 02 January 2019

Distinct effects of the soluble versus membrane-bound forms of the notch ligand delta-4 on human CD34+CD38low cell expansion and differentiation

scientific article published on 29 November 2007

Distinct effects of thrombopoietin depending on a threshold level of activated Mpl in BaF-3 cells

scientific article published on 01 June 2002

Distinct localizations and roles of non-muscle myosin II during proplatelet formation and platelet release

scientific article published on 01 April 2015

Does increasing the JAK2V617F assay sensitivity allow to identify more patients with MPN?

scientific article published on 4 May 2012

Down-regulation of the RUNX1-target gene NR4A3 contributes to hematopoiesis deregulation in familial platelet disorder/acute myelogenous leukemia.

scientific article published in July 2011

Downregulation of GATA1 drives impaired hematopoiesis in primary myelofibrosis

scientific article published on 27 February 2017

Dysmegakaryopoiesis of FPD/AML pedigrees with constitutional RUNX1 mutations is linked to myosin II deregulated expression

scientific article published on 16 August 2012

EKLF restricts megakaryocytic differentiation at the benefit of erythrocytic differentiation

scientific article

ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia.

scientific article published in March 2017

EZH2: a molecular switch of the MPN phenotype

scientific article published on 01 June 2016

Early and Persistent Bone Marrow Hematopoiesis Defect in Simian/Human Immunodeficiency Virus-Infected Macaques despite Efficient Reduction of Viremia by Highly Active Antiretroviral Therapy during Primary Infection ⬇️

scientific article published on December 1, 2001

Early erythroid markers as probes for normal and leukaemic erythroid differentiation

scientific article published on 01 November 1987

Ectopic expression of the erythropoietin receptor in a murine interleukin-6-dependent plasmacytoma cell line (TEPC-2027) confers proliferative responsiveness to erythropoietin.

scientific article published on January 1997

Effects of bone marrow-derived cells on monocrotaline- and hypoxia-induced pulmonary hypertension in mice.

scientific article published on 30 January 2007

Effects of cytokines on platelet production from blood and marrow CD34+ cells

scientific article published on 01 February 1998

Effects of five recombinant hematopoietic growth factors on enriched human erythroid progenitors in serum-replaced cultures

scientific article published on 01 March 1989

Effects of granulocyte-macrophage colony-stimulating factor and erythropoietin on leukemic erythroid colony formation in human early erythroblastic leukemias

scientific article published on 01 October 1987

Effects of the recombinant hematopoietic growth factors interleukin-3, interleukin-6, stem cell factor, and leukemia inhibitory factor on the megakaryocytic differentiation of CD34+ cells

scientific article published on 01 July 1993

Efficient ex vivo expansion of NOD/SCID-repopulating cells with lympho-myeloid potential in hematopoietic grafts of children with solid tumors

scientific article published on 01 January 2001

Elevated Hb F associated with beta-thalassaemia trait: haemoglobin synthesis in reticulocytes and in blood BFU-E

scientific article published on 01 October 1980

Elevated HbF associated with an unstable hemoglobin, hemoglobin Saint Etienne: Hb synthesis in blood BFUe in culture ⬇️

scientific article published on August 1, 1979

Eltrombopag, a potent stimulator of megakaryopoiesis.

scientific article published on December 2016

Embryonic and fetal hemoglobin synthesis in K562 cell line

scientific article published on 01 January 1981

Emergence of a BCR-ABL translocation in a patient with the JAK2V617F mutation: evidence for secondary acquisition of BCR-ABL in the JAK2V617F clone.

scientific article published on 10 February 2014

Endomitosis of human megakaryocytes are due to abortive mitosis.

scientific article

Erythroid progenitors in polycythemia vera: demonstration of their hypersensitivity to erythropoietin using serum free cultures

scientific article published on 01 February 1982

Erythroid properties of K562 cells. Effect of hemin, butyrate and TPA induction

scientific article published on 01 July 1983

Erythropoietin induces the association of phosphatidylinositol 3'-kinase with a tyrosine-phosphorylated protein complex containing the erythropoietin receptor.

scientific article published on September 1993

Evaluation of hematopoietic potential generated by transplantation of muscle-derived stem cells in mice.

scientific article

Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis

scientific article published on 20 August 2007

Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis.

scientific article published on 5 September 2006

Ex vivo expanded mobilized peripheral blood CD34+ cells accelerate haematological recovery in a baboon model of autologous transplantation

scientific article published on 01 April 2000

Ex vivo expansion marginally amplifies repopulating cells from baboon peripheral blood mobilized CD34+ cells

scientific article published on 01 June 2002

Expression and function of the collagen receptor GPVI during megakaryocyte maturation.

scientific article

Expression of CD34 and platelet glycoproteins during human megakaryocytic differentiation ⬇️

scientific article published on December 15, 1992

Expression of CD4 by human hematopoietic progenitors ⬇️

scientific article published on November 15, 1994

Expression of SSEA-I antigen (3-fucosyl-N-acetyl-lactosamine) on normal and leukaemic human haemopoietic cells: modulation by neuraminidase treatment ⬇️

scientific article published on December 1, 1984

Expression of a foreign protein in human megakaryocytes and platelets by retrovirally mediated gene transfer.

scientific article published on January 1999

Expression of blood group A antigen during erythroid differentiation in A1 and A2 subjects

scientific article published on 01 January 1987

Expression of interleukin 6 and its specific receptor by untreated and PMA-stimulated human erythroid and megakaryocytic cell lines.

scientific article published on January 1991

Expression of osteoprotegerin mRNA and protein in murine megakaryocytes

scientific article published on 01 November 2003

Expression of platelet glycoproteins by erythroid blasts in four cases of trisomy 21

Expression of platelet membrane glycoproteins and alpha-granule proteins by a human erythroleukemia cell line (HEL).

scientific article published on February 1984

Expression of platelet proteins during maturation of human megakaryocytes and of the K 562/HEL cell lines

scientific article published on 01 January 1986

Expression of tal-1 and GATA-binding proteins during human hematopoiesis

scientific article

Expression of the c-fos protooncogene by human and murine erythroblasts

scientific article published on 01 August 1989

Expression of vimentin intermediate filament cytoskeleton in acute nonlymphoblastic leukemias

scientific article published on 01 June 1985

F-cells are preferentially distributed among high density erythrocytes

scientific article published on 01 July 1981

FLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopenia

scientific article

FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis.

scientific article

Fetal hemoglobin synthesis in culture of early erythroid precursors (BFU-E) from the blood of normal adults

scientific article published on 01 March 1980

From hematopoietic stem cells to platelets.

scientific article published on July 2007

From the v-mpl oncogene to thrombopoietin

scientific article published on 01 April 1995

Fucoidan promotes early step of cardiac differentiation from human embryonic stem cells and long-term maintenance of beating areas.

scientific article published on 14 February 2014

Generation and characterisation of Rhd and Rhag null mice

scientific journal article

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis

scientific article published on 12 September 2017

Genetic and clinical implications of the Val617Phe JAK2 mutation in 72 families with myeloproliferative disorders

scientific article published on 14 March 2006

Genetic basis and molecular pathophysiology of classical myeloproliferative neoplasms

scientific article published on 27 December 2016

Germ-line JAK2 mutations in the kinase domain are responsible for hereditary thrombocytosis and are resistant to JAK2 and HSP90 inhibitors

scientific article published on 07 January 2014

Germline duplication of ATG2B and GSKIP predisposes to familial myeloid malignancies

scientific article published on 17 August 2015

Germline genetic factors in the pathogenesis of myeloproliferative neoplasms

scientific article published on 29 May 2020

Gfi-1B plays a critical role in terminal differentiation of normal and transformed erythroid progenitor cells

scientific article

Globin-chain affinity chromatography on Sepharose-haptoglobin: a new method of study of hemoglobin synthesis in reticulocytes, in bone marrow and in colonies of erythroid precursors

scientific article published on 01 December 1980

Glycoprotein I identification during normal and pathological megakaryocytic maturation

scientific article published on January 1, 1983

Gray platelet syndrome: immunoelectron microscopic localization of fibrinogen and von Willebrand factor in platelets and megakaryocytes

scientific article published on 01 December 1985

Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis.

scientific article published on August 1994

Growth of erythroid colonies in chronic myelogenous leukemia is independent of erythropoietin only in the presence of steel factor

scientific article published on 01 November 1994

Growth of human megakaryocyte colonies in culture from fetal, neonatal, and adult peripheral blood cells: ultrastructural analysis

scientific article published in March 1979

HLA-DR restriction in suppression of hematopoiesis by T cells from allogeneic bone marrow transplants

scientific article published on 01 May 1986

Hb Kokura alpha 2 47 (CE5) Asp----Gly beta 2 in a French Jewish family

scientific article published on 01 January 1986

Hb switching in neonatal cultures. Increase of Hb A synthesis in presence of an erythroid potentiating activity (EPA)

scientific article published on 01 February 1982

Hematopoietic growth factors and human megakaryocyte differentiation

scientific article published on 01 January 1992

Hematopoietic-promoting activity of the murine stromal cell line MS-5 is not related to the expression of the major hematopoietic cytokines.

scientific article

Hemin regulates the expression of transferrin receptors in human hematopoietic cell lines

scientific article published on 01 August 1982

Hemoglobin expression in clones of K-562 cell line

scientific article published on 01 January 1982

Hemoglobin expression in clones of K562 cell line

scientific article published on 01 January 1982

Hemoglobin synthesis in 7-day and 14-day-old erythroid colonies from the bone marrow of normal individuals

scientific article published on 01 January 1980

Hemostatic disorders in a JAK2V617F-driven mouse model of myeloproliferative neoplasm

scientific article

Heterozygous and homozygous JAK2(V617F) states modeled by induced pluripotent stem cells from myeloproliferative neoplasm patients

scientific article

High molecular response rate of polycythemia vera patients treated with pegylated interferon alpha-2a

scientific article

High thrombopoietin production by hematopoietic cells induces a fatal myeloproliferative syndrome in mice

scientific article published on 01 December 1997

Human platelet alpha granules contain a nonspecific inhibitor of megakaryocyte colony formation: its relationship to type beta transforming growth factor (TGF-beta)

scientific article published on 01 January 1988

Hydrocortisone differentially affects the ability of murine stromal cells and human marrow-derived adherent cells to promote the differentiation of CD34++/CD38- long-term culture-initiating cells.

scientific article published on December 1994

Identification of CXCR4 as a new nitric oxide-regulated gene in human CD34+ cells.

scientific article

Identification of MPL R102P Mutation in Hereditary Thrombocytosis.

scientific article published on 20 September 2017

Identification of human T-lymphoid progenitor cells in CD34+CD38low and CD34+CD38+ subsets of human cord blood and bone marrow cells using NOD-SCID fetal thymus organ cultures

article

Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling

scientific article published on 18 January 2013

Immunological characterization of the leukemic megakaryocytic line at light and electron microscopic levels.

scientific article published in January 1984

Immunological study of in vitro maturation of human megakaryocytes

scientific article published on 01 April 1984

Immunophenotype of leukemic blasts with small peroxidase-positive granules detected by electron microscopy

scientific article published on 01 May 1988

Immunosuppression by Mutated Calreticulin Released from Malignant Cells

scientific article published on 27 November 2019

Impaired megakaryocytopoiesis in type 2B von Willebrand disease with severe thrombocytopenia

scientific article

In vitro effects of hematopoietic growth factors on the proliferation, endoreplication, and maturation of human megakaryocytes

scientific article published on 01 June 1991

In vitro infection of bone marrow-adherent cells by human immunodeficiency virus type 1 (HIV-1) does not alter their ability to support hematopoiesis.

scientific article

In vitro inhibition of hematopoiesis by HNK1, DR-positive T cells and monocytes after allogeneic bone marrow transplantation

scientific article published on 01 January 1987

In vitro inhibition of normal human hematopoiesis by marrow CD3+, CD8+, HLA-DR+, HNK1+ lymphocytes

scientific article published on 01 November 1988

Incidence and prognostic value of TET2 alterations in de novo acute myeloid leukemia achieving complete remission.

scientific article published on 20 May 2010

Individual CD34+CD38lowCD19-CD10- progenitor cells from human cord blood generate B lymphocytes and granulocytes

scientific article published on 01 May 1997

Induced Pluripotent Stem Cells Enable Disease Modeling and Drug Screening in Calreticulin del52 and ins5 Myeloproliferative Neoplasms

scientific article

Induction of myeloproliferative disorder and myelofibrosis by thrombopoietin receptor W515 mutants is mediated by cytosolic tyrosine 112 of the receptor.

scientific article

Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors

scientific article published on 6 July 2011

Inhibition of angiotensin I-converting enzyme induces radioprotection by preserving murine hematopoietic short-term reconstituting cells

scientific article published on 22 April 2004

Inhibition of erythroid differentiation and induction of megakaryocytic differentiation by thrombopoietin are regulated by two different mechanisms in TPO-dependent UT-7/c-mpl and TF-1/c-mpl cell lines

scientific article published on 01 September 1998

Inhibition of insulin receptor binding by phorbol esters.

scientific article published in December 1982

Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach

scientific article published on 14 December 2006

Intracellular localization and constitutive endocytosis of CXCR4 in human CD34+ hematopoietic progenitor cells.

scientific article published in January 2004

Isolation and culture of megakaryocyte precursors.

scientific article published in January 2004

JAK inhibitors for the treatment of myeloproliferative neoplasms and other disorders.

scientific article

JAK/STAT signaling in hematological malignancies.

scientific article

JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.

scientific article published on 19 October 2005

JAK2 and MPL protein levels determine TPO-induced megakaryocyte proliferation vs differentiation.

scientific article

JAK2 inhibition has different therapeutic effects according to myeloproliferative neoplasm development in mice

scientific article

JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders.

scientific article

JAK2, the JAK2 V617F mutant and cytokine receptors.

scientific article

JAK2V617F expression in mice amplifies early hematopoietic cells and gives them a competitive advantage that is hampered by IFNα.

scientific article published on 17 July 2013

JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis.

scientific article

JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML

scientific article published on 01 February 2021

JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma.

scientific article published on 21 May 2013

JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies.

scientific article

K562 cells induced to differentiate by phorbol ester tumor promotors resist NK lysis

scientific article published on 01 September 1984

Kit-activating mutations cooperate with Spi-1/PU.1 overexpression to promote tumorigenic progression during erythroleukemia in mice.

scientific article published on December 2005

Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development

scientific article published on 30 August 2019

LYL-1 deficiency induces a stress erythropoiesis

scientific article published on 21 March 2011

Level of RUNX1 activity is critical for leukemic predisposition but not for thrombocytopenia.

scientific article

Ligand-independent thrombopoietin mutant receptor requires cell surface localization for endogenous activity

scientific article published on 04 March 2009

Limits of phenotypic markers for the diagnosis of megakaryoblastic leukemia

scientific article published on 01 January 1989

Localization of platelet osteonectin at the internal face of the alpha-granule membranes in platelets and megakaryocytes

scientific article

Loss of attachment to fibronectin with terminal human erythroid differentiation

scientific article published on 01 February 1990

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9.

scientific article

MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors

scientific article published on 01 September 2019

MYH10 protein expression in platelets as a biomarker of RUNX1 and FLI1 alterations.

scientific article

Macrophage migration inhibitory factor is overproduced through EGR1 in TET2<sup>low</sup> resting monocytes

scientific article published on 03 February 2022

Mammalian target of rapamycin (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation.

scientific article

Mechanisms of WASp-mediated hematologic and immunologic disease.

scientific article published on 12 August 2004

Megakaryocyte and polyploidization

scientific article published on 27 October 2017

Megakaryocyte colony formation from human bone marrow precursors ⬇️

scientific article published on October 1, 1979

Megakaryocyte cultures in the chronic phase and in the blast crisis of chronic myeloid leukaemia: studies on the differentiation of the megakaryocyte progenitors and on the maturation of megakaryocytes in vitro

scientific article published on 01 May 1982

Megakaryocyte endomitosis is a failure of late cytokinesis related to defects in the contractile ring and Rho/Rock signaling

scientific article

Megakaryocyte polyploidization is associated with a functional gene amplification

article

Megakaryocyte polyploidization: role in platelet production

scientific article published on 22 September 2019

Megakaryocytes tame erythropoiesis with TGFβ1

scientific article published on 01 August 2020

Megakaryocytic and erythrocytic lineages share specific transcription factors

scientific article

Megakaryopoiesis: regulation of platelet production by thrombopoietin

scientific article

Microarray analysis of LIF/Stat3 transcriptional targets in embryonic stem cells

scientific article published on 11 August 2005

Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.

scientific article published on May 2004

Molecular and genetic bases of myeloproliferative disorders: questions and perspectives.

scientific article published on January 2009

Molecular pathophysiology of chronic myelogenous leukemia

scientific article published on 01 October 1998

Monoclonal antibodies specific for human platelet membrane glycoproteins bind to monocytes by focal absorption of platelet membrane fragments: an ultrastructural immunogold study

scientific article published on 01 February 1987

Monocyte/macrophage dysfunctions do not impair the promotion of myelofibrosis by high levels of thrombopoietin

scientific article published on 01 June 2006

Monocytic cells derived from human embryonic stem cells and fetal liver share common differentiation pathways and homeostatic functions

scientific article

Morphological Abnormalities in Cultured Erythroid Colonies (BFU-E) from the Blood of Two Patients with HEMPAS

scientific article published on July 1, 1979

Mpl ligand (thrombopoietin) and platelet regulation

scientific article

Mpl ligand or thrombopoietin: biological activities.

scientific article published on January 1998

MplK, a natural variant of the thrombopoietin receptor with a truncated cytoplasmic domain, binds thrombopoietin but does not interfere with thrombopoietin-mediated cell growth.

scientific article published on February 2002

Multilayer intraclonal heterogeneity in chronic myelomonocytic leukemia

scientific article published on 02 May 2019

Multiple signaling pathways are involved in erythropoietin-independent differentiation of erythroid progenitors in polycythemia vera.

scientific article published in February 2004

Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules.

scientific article published on April 1998

Murine stromal cells counteract the loss of long-term culture-initiating cell potential induced by cytokines in CD34(+)CD38(low/neg) human bone marrow cells

scientific article published on 01 July 1999

Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents

scientific article published on 24 February 2016

Mutations du gèneTET2dans les hémopathies myéloïdes humaines

article

Mutations in JAK2V617F homologous domain of JAK genes are uncommon in solid tumors

article

Mutations in exon 12 of JAK2 are mainly found in JAK2 V617F-negative polycythaemia vera patients.

scientific article published on 22 May 2008

Mutations in the SRP54 gene cause severe congenital neutropenia as well as Shwachman-Diamond-like syndrome

scientific article published on 18 June 2018

Mutations of ASXL1 gene in myeloproliferative neoplasms.

scientific article published on 16 July 2009

Myelofibrosis, JAK2 inhibitors and erythropoiesis.

scientific article published in June 2013

Myeloid and megakaryocytic properties of K-562 cell lines

scientific article published on 01 October 1983

Myeloproliferative Neoplasms: Molecular Pathophysiology, Essential Clinical Understanding, and Treatment Strategies ⬇️

scientific article published on January 10, 2011

Myeloproliferative neoplasm induced by constitutive expression of JAK2V617F in knock-in mice.

scientific article published on 14 May 2010

Myeloproliferative neoplasms: JAK2 signaling pathway as a central target for therapy.

scientific article published on September 2014

NK cell activation by dendritic cells (DCs) requires the formation of a synapse leading to IL-12 polarization in DCs.

scientific article published on 8 July 2004

NK cell sensitivity of the leukemic K 562 cells; effect of sodium butyrate and hemin induction.

scientific article published in January 1982

New hematopoietic differentiation antigens detected by anti-K562 monoclonal antibodies

scientific article published on 01 October 1988

New insights into the pathogenesis of JAK2 V617F-positive myeloproliferative disorders and consequences for the management of patients.

scientific article published on June 2006

New mutations and pathogenesis of myeloproliferative neoplasms.

scientific article published on 07 June 2011

New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition

scientific article published on 05 June 2008

New pathogenic mechanisms induced by germline erythropoietin receptor mutations in primary erythrocytosis.

scientific article published on 21 December 2017

Non-apoptotic functions of caspases in myeloid cell differentiation.

scientific article published on 17 February 2017

Normal human serum contains a factor(s) capable of inhibiting megakaryocyte colony formation

scientific article published on 01 September 1982

Notch/Delta4 interaction in human embryonic liver CD34+ CD38- cells: positive influence on BFU-E production and LTC-IC potential maintenance.

scientific article published in April 2005

Notch/Delta4 signaling inhibits human megakaryocytic terminal differentiation.

scientific article published on 9 September 2010

Novel activating JAK2 mutation in a patient with Down syndrome and B-cell precursor acute lymphoblastic leukemia.

scientific article published on 26 October 2006

Oligodeoxynucleotides antisense to the proto-oncogene c-mpl specifically inhibit in vitro megakaryocytopoiesis.

scientific article

Oncogenic kinases of myeloproliferative disorders induce both protein synthesis and G1 activators

scientific article published on 10 August 2006

Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia

scientific article published on 29 October 2019

Orientation-specific signalling by thrombopoietin receptor dimers.

scientific article published on 2 September 2011

Osteopontin is upregulated by BCR-ABL

scientific article published on 01 August 2005

Overexpression of FKBP51 in idiopathic myelofibrosis regulates the growth factor independence of megakaryocyte progenitors

scientific article (publication date: 15 October 2002)

Overexpression of the partially activated alpha(IIb)beta3D723H integrin salt bridge mutant downregulates RhoA activity and induces microtubule-dependent proplatelet-like extensions in Chinese hamster ovary cells.

scientific article published on 22 May 2009

P19INK4D links endomitotic arrest and megakaryocyte maturation and is regulated by AML-1.

scientific article published on 14 February 2008

P53 activation inhibits all types of hematopoietic progenitors and all stages of megakaryopoiesis.

scientific article

P53 deletion and NrasG12D cooperate for AML

scientific article published on 01 January 2017

Pathogenesis of myelofibrosis with myeloid metaplasia: Insight from mouse models.

scientific article published on January 2006

Pathologic activation of thrombopoietin receptor and JAK2-STAT5 pathway by frameshift mutants of mouse calreticulin.

scientific article published on 29 February 2016

Pattern of pyruvate kinase isozymes in erythroleukemia cell lines and in normal human erythroblasts

scientific article published on 01 October 1984

Peroxidatic activity distinct from myeloperoxidase in human monocytes cultured in vitro and in alveolar macrophages.

scientific article published in January 1982

Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation

scientific article published on 31 March 2014

Phenotype and function of human hematopoietic cells engrafting immune-deficient CB17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells

scientific article published on 01 November 1996

Platelet formation is the consequence of caspase activation within megakaryocytes

scientific article published in August 2002

Posttransfusion purpura-like syndrome associated with CD36 (Naka) isoimmunization.

scientific article

Preferential liver irradiation enhances hematopoiesis through a thrombopoietin-independent mechanism

scientific article published on 01 October 1999

Presence of a defect in karyokinesis during megakaryocyte endomitosis

scientific article published on 16 November 2012

Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients

scientific article published on 8 October 2015

Presence of cross-reactive antibody between human immunodeficiency virus (HIV) and platelet glycoproteins in HIV-related immune thrombocytopenic purpura ⬇️

scientific article published on July 1, 1992

Presence of the Tn antigen on hematopoietic progenitors from patients with the Tn syndrome

scientific article

Primary hematopoietic cells from DBA patients with mutations in RPL11 and RPS19 genes exhibit distinct erythroid phenotype in vitro.

scientific article

Prognostic score including gene mutations in chronic myelomonocytic leukemia.

scientific article

Prominent role of TGF-beta 1 in thrombopoietin-induced myelofibrosis in mice

scientific article published on 05 July 2002

Properties and biological roles of TET proteins during embryogenesis and in hematopoiesis

scientific article

Proplatelet formation is regulated by the Rho/ROCK pathway

scientific article published on 23 January 2007

Proteasome inhibitor bortezomib impairs both myelofibrosis and osteosclerosis induced by high thrombopoietin levels in mice.

scientific article published on 20 March 2007

Protective effects of differentiation inducers on natural killer sensitivity of K 562 cells: Analysis at a single-cell level.

scientific article

Protein kinase C mediates the mitogenic action of thrombopoietin in c-Mpl-expressing UT-7 cells.

scientific article

Putative innate immunity of antiatherogenic paraoxanase-2 via STAT5 signal transduction in HIV-1 infection of hematopoietic TF-1 cells and in SCID-hu mice.

scientific article published on January 2010

Pyruvate kinase synthesis and degradation by normal and pathologic cells during erythroid maturation

scientific article published on 01 September 1988

Quantitative and qualitative in vitro analysis of the stem cell potential of hematopoietic cells purified from murine skeletal muscle

scientific article published on 01 September 2007

RGS16 is a negative regulator of SDF-1-CXCR4 signaling in megakaryocytes.

scientific article published on 5 July 2005

RNA interference shows critical requirement for NF-kappa B p50 in the production of IL-12 by human dendritic cells

scientific article published on August 2003

RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization

scientific article

Radiation-induced expression of functional Fas ligand in EBV-positive human nasopharyngeal carcinoma cells.

scientific article published on April 2000

Rare type 1-like and type 2-like calreticulin mutants induce similar myeloproliferative neoplasms as prevalent type 1 and 2 mutants in mice

scientific article published on 19 October 2018

Recent advances in understanding myelofibrosis and essential thrombocythemia

scientific article

Recurrent V75M mutation within the Wiskott-Aldrich syndrome protein: description of a homozygous female patient.

scientific article

Reduced retention of radioprotective hematopoietic cells within the bone marrow microenvironment in CXCR4-/- chimeric mice.

scientific article

Regulation of i- and I-antigen expression in the K562 cell line.

scientific article published in November 1982

Regulation of megakaryocyte maturation and platelet formation.

scientific article published on July 2009

Regulation of the expression of IL-6 in human monocytes

scientific article published on 01 June 1989

Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging

scientific article published on 11 July 2019

Reticulocytosis, hypochromia, and microcytosis: an unusual presentation of the preleukemic syndrome

scientific article published on 01 February 1982

Retrovirus-Mediated Gene Transfer into Human CD34+38lowPrimitive Cells Capable of Reconstituting Long-Term CulturesIn Vitroand Nonobese Diabetic–Severe Combined Immunodeficiency MiceIn Vivo ⬇️

scientific article published on July 1, 1998

Retrovirus-mediated transfer of the erythropoietin gene in hematopoietic cells improves the erythrocyte phenotype in murine beta-thalassemia.

scientific article

Rifampicin-induced pure red cell aplasia.

scientific article

Role for the nuclear factor kappaB pathway in transforming growth factor-beta1 production in idiopathic myelofibrosis: possible relationship with FK506 binding protein 51 overexpression

scientific article

Role of granulocyte-macrophage colony-stimulating factor, interleukin-3 and interleukin-5 in the eosinophilia associated with T cell lymphoma

scientific article published on 01 March 1993

Role of human immunodeficiency virus replication in defective in vitro growth of hematopoietic progenitors ⬇️

scientific article published on December 15, 1992

Role of p21Cip1/Waf1 in cell-cycle exit of endomitotic megakaryocytes ⬇️

scientific article published on December 1, 2001

Role of tyrosine kinases and phosphatases in polycythemia vera.

scientific article

SOCS3 inhibits TPO-stimulated, but not spontaneous, megakaryocytic growth in primary myelofibrosis.

scientific article published on 19 February 2009

STAT3 mutations identified in human hematologic neoplasms induce myeloid malignancies in a mouse bone marrow transplantation model.

scientific article published on 19 July 2013

Selective reduction of JAK2V617F-dependent cell growth by siRNA/shRNA and its reversal by cytokines.

scientific article published on 9 July 2009

Simultaneous detection of membrane markers with monoclonal antibodies and peroxidatic activities in leukaemia: ultrastructural analysis using a new method of fixation preserving the platelet peroxidase

scientific article published on 01 November 1984

Small-molecule inhibitors in myeloproliferative neoplasms: are we aiming for the right targets?

scientific article published on January 1, 2012

Specific involvement of caspases in the differentiation of monocytes into macrophages

scientific article

Spi-1 transgenic mice develop a clonal erythroleukemia which does not depend on p53 mutation ⬇️

scientific article published on June 11, 1998

Spontaneous STAT5 activation induces growth factor independence in idiopathic myelofibrosis: possible relationship with FKBP51 overexpression.

scientific article published on July 2003

Stimulation of osteoprotegerin production is responsible for osteosclerosis in mice overexpressing TPO.

scientific article published on 27 December 2002

Stromal cells maintain the radioprotective capacity of CFU-S during retroviral infection.

scientific article published on September 1996

Study of hemoglobin synthesis by affinity chromatography on Sepharose haptoglobin

scientific article published on 01 January 1981

Susceptibility of human bone marrow stromal cells to human immunodeficiency virus (HIV).

scientific article

TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis

TET2 deficiency inhibits mesoderm and hematopoietic differentiation in human embryonic stem cells.

scientific article published on August 2014

TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

scientific article published on October 2009

TET2 haploinsufficiency alters reprogramming into induced pluripotent stem cells

scientific article published on 06 March 2020

TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis

scientific journal article

TET2 loss, a rescue of JAK2V617F HSCs.

scientific article published in January 2015

TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs).

scientific article

TET2, a tumor suppressor in hematological disorders.

scientific article published on 03 January 2012

TET2-mediated 5-hydroxymethylcytosine induces genetic instability and mutagenesis.

scientific article published on 24 May 2016

Telomere dysfunction and telomerase reactivation in human leukemia cell lines after telomerase inhibition by the expression of a dominant-negative hTERT mutant

scientific article published on 01 November 2002

The JAK2 617V>F mutation triggers erythropoietin hypersensitivity and terminal erythroid amplification in primary cells from patients with polycythemia vera

scientific article published on 27 March 2007

The Mpl-ligand is involved in the growth-promoting activity of the murine stromal cell line MS-5 on ES cell-derived hematopoiesis.

scientific article

The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors

scientific article published on 01 October 1995

The NF-κB pathway is rarely spontaneously activated in mantle cell lymphoma (MCL) cell lines and patient's samples.

scientific article published on 14 October 2013

The Notch Delta-4 ligand helps to maintain the quiescence and the short-term reconstitutive potential of haematopoietic progenitor cells through activation of a key gene network

scientific article

The OTT-MAL fusion oncogene activates RBPJ-mediated transcription and induces acute megakaryoblastic leukemia in a knockin mouse model

scientific article

The Pediatric Acute Leukemia Fusion Oncogene ETO2-GLIS2 Increases Self-Renewal and Alters Differentiation in a Human Induced Pluripotent Stem Cells-Derived Model

scientific article published on 22 January 2020

The SCL relative LYL-1 is required for fetal and adult hematopoietic stem cell function and B-cell differentiation

scientific journal article

The Ten-Eleven Translocation-2 (TET2) gene in hematopoiesis and hematopoietic diseases

scientific article

The Tie receptor tyrosine kinase is expressed by human hematopoietic progenitor cells and by a subset of megakaryocytic cells.

scientific article

The abnormal proplatelet formation in MYH9-related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibition.

scientific article

The cell division control protein 42-Src family kinase-neural Wiskott-Aldrich syndrome protein pathway regulates human proplatelet formation.

scientific article published on 29 September 2016

The first international meeting on V617F JAK2 mutation and its relevance in Philadelphia-negative myeloproliferative disorders.

scientific article published on 9 August 2006

The formin DIAPH1 (mDia1) regulates megakaryocyte proplatelet formation by remodeling the actin and microtubule cytoskeletons.

scientific article published on 8 October 2014

The hematopoietic stem cell compartment of JAK2V617F-positive myeloproliferative disorders is a reflection of disease heterogeneity

scientific article published on 08 July 2008

The interaction between Cdc42 and WASP is required for SDF-1-induced T-lymphocyte chemotaxis.

scientific article

The myeloproliferative disorder associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3

scientific article published on 22 February 2007

The origin of human B and T cells from multipotent stem cells: a study of the Tn syndrome

scientific article published on 01 April 1983

The role of phorbol esters in the control of the proliferation and differentiation of hematopoietic cells.

scientific article published on May 1983

The role of the thrombopoietin receptor MPL in myeloproliferative neoplasms: recent findings and potential therapeutic applications

scientific article published on 22 May 2019

The serum response factor (SRF)/megakaryocytic acute leukemia (MAL) network participates in megakaryocyte development

scientific article published on 29 April 2010

The severe phenotype of Diamond-Blackfan anemia is modulated by heat shock protein 70

scientific article published on 10 October 2017

The syndrome of T8 hyperlymphocytosis: variation in phenotype and cytotoxic activities of granular cells and evaluation of their role in associated neutropenia

scientific article published on 01 April 1987

The transcription factor Srf regulates hematopoietic stem cell adhesion

scientific journal article

The value of flow cytometric analysis of platelet glycoprotein expression of CD34+ cells measured under conditions that prevent P-selectin-mediated binding of platelets

scientific article published on 01 November 1995

Therapy-related leukemia associated with myelofibrosis. Blast cell characterization in six cases.

scientific article

Thrombocytopenia in HIV infection

scientific article published on September 1, 1994

Thrombocytopenia induced by the histone deacetylase inhibitor abexinostat involves p53-dependent and -independent mechanisms.

scientific article

Thrombocytopenia resulting from mutations in filamin A can be expressed as an isolated syndrome.

scientific article

Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation

scientific article

Thrombopoietin (Mpl ligand) and the regulation of platelet production.

scientific article

Thrombopoietin (Mpl-ligand) and the regulation of platelet production.

scientific article

Thrombopoietin (TPO) knockout phenotype induced by cross-reactive antibodies against TPO following injection of mice with recombinant adenovirus encoding human TPO.

scientific article

Thrombopoietin and its receptor

scientific article published on 01 September 1998

Thrombopoietin and its receptor, the proto-oncogene c-mpl.

scientific article published on September 1995

Thrombopoietin and megakaryocyte differentiation

scientific article

Thrombopoietin does not induce lineage-restricted commitment of Mpl-R expressing pluripotent progenitors but permits their complete erythroid and megakaryocytic differentiation.

scientific article published in May 1997

Thrombopoietin from human embryonic kidney cells is the same factor as c-mpl-ligand

scientific article published on 01 January 1995

Thrombopoietin receptor activation by myeloproliferative neoplasm associated calreticulin mutants.

scientific article published on 14 December 2015

Thrombopoietin receptor down-modulation by JAK2 V617F: restoration of receptor levels by inhibitors of pathologic JAK2 signaling and of proteasomes

scientific article published on 29 February 2012

Thrombopoietin receptor is required for the oncogenic function of CALR mutants.

scientific article published on 17 February 2016

Thrombopoietin responsiveness reflects the number of doublings undergone by megakaryocyte progenitors.

scientific article published in June 2004

Thrombospondin-1 is not the major activator of TGF-β1 in thrombopoietin-induced myelofibrosis

scientific article published on 13 October 2010

Thromboxane synthase has the same pattern of expression as platelet specific glycoproteins during human megakaryocyte differentiation

scientific article published on 01 May 2000

Transfer of differentiation signal by membrane microvesicles harboring hedgehog morphogens.

scientific article

Transferrin binding to K562 cell line. Effect of heme and sodium butyrate induction

scientific article published on 01 August 1982

Treatment of pure red cell aplasia by high dose intravenous immunoglobulins

scientific article published on 01 October 1983

Two routes to leukemic transformation after a JAK2 mutation-positive myeloproliferative neoplasm.

scientific article published on 11 December 2009

Ultrastructural and cytochemical changes induced by short and prolonged culture of human monocytes

scientific article published on 01 March 1980

Ultrastructural and cytochemical characterization of blasts from early erythroblastic leukemias

scientific article published on 01 March 1987

Ultrastructure of platelet formation by human megakaryocytes cultured with the Mpl ligand

scientific article published on 01 April 1997

Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint

scientific article

Unfractionated peripheral blood stem cell autografts and CD(34+)-enriched autografts have similar long-term culture initiating capacity in multiple myeloma

scientific article published on 01 November 1999

Use of a monoclonal antibody (GA3) to demonstrate lineage restricted O-glycosylation on leukosialin during terminal erythroid differentiation

scientific article published on 01 May 1988

Use of the 46/1 haplotype to model JAK2(V617F) clonal architecture in PV patients: clonal evolution and impact of IFNα treatment.

scientific article

Wiskott-Aldrich syndrome protein-deficient hematopoietic cells can be efficiently mobilized by granulocyte colony-stimulating factor

scientific article published on 26 February 2013

[A case of erythoblastic leukemia with basophilic reaction]

scientific article published on 01 February 1991

[A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera]

scientific article published on 01 June 2005

[Cellular regulation of the expression of i and I antigens during the in vitro differentiation of BFU-E]

scientific article published on 01 September 1980

[Erythrocyte receptors of insulin]

scientific article published on 01 January 1982

[Erythropoiesis and its regulation]

scientific article published on 01 June 1993

[Ex-vivo expansion of hematopoietic stem cells: study in the primate model]

scientific article published on 01 April 1999

[Fli1 haploinsufficiency underlies Paris-Trousseau thrombopenia]

scientific article published on 01 November 2004

[From giant to micro: a platelet story]

scientific article published on 01 May 2008

[Hematopoiesis and its regulation. Comparison between erythropoiesis and megakaryocytopoiesis]

scientific article published on 01 May 1994

[Hematopoietic stem cells]

scientific article published on 01 July 2001

[Hope and limits in cell therapies]

scientific article published on 01 June 2005

[In cauda venenum or the importance of TET(2)]

scientific article published on 23 December 2011

[Physiopathologic and therapeutic importance of animal models of hemoglobinopathies]

scientific article published on 01 June 1993

[Regulation of erythropoiesis]

scientific article published on 01 June 1993

[Treatment of chronic autoimmune thrombopenic purpura with intravenous immunoglobulins. Study of 18 cases]

scientific article published on 01 January 1983

c-jun and c-fos are expressed by human megakaryocytes.

scientific article published in August 1992

c-mpl, the thrombopoietin receptor

scientific article published on 01 July 1995

miR-28 is a thrombopoietin receptor targeting microRNA detected in a fraction of myeloproliferative neoplasm patient platelets.

scientific article

p19 INK4d controls hematopoietic stem cells in a cell-autonomous manner during genotoxic stress and through the microenvironment during aging

scientific article

p210BCR-ABL inhibits SDF-1 chemotactic response via alteration of CXCR4 signaling and down-regulation of CXCR4 expression

scientific article

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