List of works by Thomas J. Hudson

1alpha,25-dihydroxy-vitamin D3 stimulation of bronchial smooth muscle cells induces autocrine, contractility, and remodeling processes.

scientific article published on 9 January 2007

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016

scientific article published oln 16 November 2016

4th Pediatric Allergy and Asthma Meeting (PAAM)

scientific article (publication date: November 2016)

5' flanking variants of resistin are associated with obesity

scientific article published in May 2002

A PCR-based linkage map of human chromosome 1.

scientific article published in February 1993

A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition

scientific article published on 17 January 2013

A Second-Generation Association Study of the 5q31 Cytokine Gene Cluster and the Interleukin-4 Receptor in Asthma

article

A YAC-based physical map of the mouse genome.

scientific article

A cis-Acting Regulatory Variant in the IL2RA Locus

scientific article published on 30 September 2009

A combinatorial network of evolutionarily conserved myelin basic protein regulatory sequences confers distinct glial-specific phenotypes

scientific journal article

A combined watershed and level set method for segmentation of brightfield cell images

article

A common RET variant is associated with reduced newborn kidney size and function

scientific article published on October 2008

A common variant of the PAX2 gene is associated with reduced newborn kidney size

scientific article

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

scientific article

A genetic linkage map of the vervet monkey (Chlorocebus aethiops sabaeus).

scientific article

A genome-wide approach to identifying novel-imprinted genes.

scientific article

A genome-wide association study for colorectal cancer identifies a risk locus in 14q23.1.

scientific article

A genome-wide association study identifies novel risk loci for type 2 diabetes

scientific article

A map of 75 human ribosomal protein genes

scientific article

A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis

scientific article

A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis

A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality

scientific article

A radiation hybrid map of mouse genes

article

A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns

scientific article

A second generation human haplotype map of over 3.1 million SNPs

scientific article

A sequence variation in the mitochondrial glycerol-3-phosphate dehydrogenase gene is associated with increased plasma glycerol and free fatty acid concentrations among French Canadians.

scientific article

A survey of genetic and epigenetic variation affecting human gene expression

scientific article published on 15 January 2004

ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels.

scientific article

ARSACS, a spastic ataxia common in northeastern Québec, is caused by mutations in a new gene encoding an 11.5-kb ORF

scientific article

Absence of linkage between inflammatory bowel disease and selected loci on chromosomes 3, 7, 12, and 16

scientific article published on 01 November 1998

Abstract 2190: Fine-mapping of common genetic variants associated with colorectal tumor risk identified potential functional variants

Abstract 4831: Additive and multiplicative gene-environment interactions for colorectal cancer risk

article

Activation of hedgehog signaling associates with early disease progression in chronic lymphocytic leukemia

scientific article published on 28 March 2019

Allele-specific expression in the germline of patients with familial pancreatic cancer: an unbiased approach to cancer gene discovery

scientific article

An atypical form of erythrokeratodermia variabilis maps to chromosome 7q22.

scientific article published on 25 November 2004

An evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population

scientific article

An optimized set of human telomere clones for studying telomere integrity and architecture.

scientific article

Analyses of associations with asthma in four asthma population samples from Canada and Australia

scientific article

Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases.

scientific article published on 11 April 2016

Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation

scientific journal article

Assessing the validity of the association between the SUMO4 M55V variant and risk of type 1 diabetes

scientific article (publication date: February 2005)

Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants

scientific article

Association of common variation in the HNF1alpha gene region with risk of type 2 diabetes

scientific article published on 01 August 2005

Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes

scientific article published on 01 December 2004

Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people

scientific article published in June 2005

Association testing of variants in the hepatocyte nuclear factor 4alpha gene with risk of type 2 diabetes in 7,883 people

scientific article published on 01 March 2005

Asthma and genes encoding components of the vitamin D pathway

scientific article

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS): high-resolution physical and transcript map of the candidate region in chromosome region 13q11.

scientific article

Autosomal recessive spastic ataxia of Charlevoix–Saguenay

article published in 1998

CAG expansion in the Huntington disease gene is associated with a specific and targetable predisposing haplogroup

scientific article

CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk

scientific article published on 14 January 2016

Characterization of a common susceptibility locus for asthma-related traits

scientific article

Characterization of gene-environment interactions for colorectal cancer susceptibility loci

scientific article

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

scientific article published on 21 December 2008

Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer.

scientific article published on 21 July 2016

Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

scientific article published on 01 July 2019

Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci

scientific article published on 26 October 2015

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

scientific article

Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals

scientific article published on 05 April 2012

Discovery of common and rare genetic risk variants for colorectal cancer

scientific article published on 03 December 2018

Disease variants alter transcription factor levels and methylation of their binding sites

scientific article published on 5 December 2016

Disruption of AP1S1, causing a novel neurocutaneous syndrome, perturbs development of the skin and spinal cord

scientific article published in December 2008

FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A

scientific article

Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants

scientific article

Functional classes of bronchial mucosa genes that are differentially expressed in asthma

scientific article

G-protein-coupled receptors and asthma endophenotypes: the cysteinyl leukotriene system in perspective

scientific article (publication date: 2006)

Genes to diseases (G2D) computational method to identify asthma candidate genes

scientific article published on 6 August 2008

Genetic mechanisms of immune evasion in colorectal cancer

scientific article published on 6 March 2018

Genetic predictors of circulating 25-hydroxyvitamin d and risk of colorectal cancer

scientific article published on 27 August 2013

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

article

Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease

article

Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis

scientific article

Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer

scientific article

Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

scientific article published on 30 March 2008

Genome-wide association study of colorectal cancer identifies six new susceptibility loci

scientific article published on 07 July 2015

Genome-wide detection and characterization of positive selection in human populations

scientific article

Genome-wide meta-analysis of common variant differences between men and women

scientific article published on 27 July 2012

Genome-wide search for gene-gene interactions in colorectal cancer

scientific article

Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height

scientific article

Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region

scientific article published in May 2004

Hyperhomocysteinemia due to methionine synthase deficiency, cblG: structure of the MTR gene, genotype diversity, and recognition of a common mutation, P1173L

scientific article

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

scientific article published on 22 December 2012

Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer

scientific article

Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics

scientific article

Identification of genes expressed by immune cells of the colon that are regulated by colorectal cancer-associated variants

scientific article

Identification of the gene responsible for the cblA complementation group of vitamin B12-responsive methylmalonic acidemia based on analysis of prokaryotic gene arrangements

scientific article

International network of cancer genome projects

scientific article

Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival

scientific article published on 20 July 2020

Location score and haplotype analyses of the locus for autosomal recessive spastic ataxia of Charlevoix-Saguenay, in chromosome region 13q11.

scientific article

Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci

scientific article

Meta-analysis identifies seven susceptibility loci involved in the atopic march

scientific article

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

scientific article

Meta-analysis of new genome-wide association studies of colorectal cancer risk

scientific article published on 15 July 2011

Mutations in TMEM76* cause mucopolysaccharidosis IIIC (Sanfilippo C syndrome)

scientific article

No evidence of gene-calcium interactions from genome-wide analysis of colorectal cancer risk

scientific article

Novel Common Genetic Susceptibility Loci for Colorectal Cancer

scientific article published on 01 February 2019

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

scientific article

Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia

scientific article published on 09 August 2013

Prepublication data sharing

scientific article

Spatial genomic heterogeneity within localized, multifocal prostate cancer

scientific article published on 25 May 2015

The K5 Lyase KflA Combines a Viral Tail Spike Structure with a Bacterial Polysaccharide Lyase Mechanism

scientific article

The acute neurotoxicity of mefloquine may be mediated through a disruption of calcium homeostasis and ER function in vitro

scientific article

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

scientific article

The genetic basis for cancer treatment decisions

scientific article

The molecular basis of glutamate formiminotransferase deficiency

scientific journal article