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List of works by David Durantel

A dual role for hepatocyte-intrinsic canonical NF-κB signaling in virus control

scientific article published on 15 January 2020

A first experience of transduction for differentiated HepaRG cells using lentiviral technology

scientific article published on 09 September 2019

A new immune competent mouse model for the study of hepatitis D virus infection

scientific article published in June 2017

A new strategy for studying in vitro the drug susceptibility of clinical isolates of human hepatitis B virus.

scientific article published on October 2004

A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses.

scientific article published on 29 July 2015

Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors

scientific article published on 27 February 2015

Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases.

scientific article published on June 2013

An immortalized human liver endothelial sinusoidal cell line for the study of the pathobiology of the liver endothelium

scientific article

Antiviral activity of various interferons and pro-inflammatory cytokines in non-transformed cultured hepatocytes infected with hepatitis B virus

scientific article published on 10 March 2016

Antiviral effect of N-butyldeoxynojirimycin against bovine viral diarrhea virus correlates with misfolding of E2 envelope proteins and impairment of their association into E1-E2 heterodimers

scientific article

Antiviral effect of alpha-glucosidase inhibitors on viral morphogenesis and binding properties of hepatitis C virus-like particles.

scientific article published on April 2006

Antiviral therapies and prospects for a cure of chronic hepatitis B.

scientific article

Characterization of Pattern Recognition Receptor Expression and Functionality in Liver Primary Cells and Derived Cell Lines

scientific article published on 05 July 2018

Characterization of the Inflammasome in Human Kupffer Cells in Response to Synthetic Agonists and Pathogens.

scientific article

Characterization of the double-stranded RNA responses in human liver progenitor cells

scientific article published on 5 February 2008

Circulating and Hepatic BDCA1+, BDCA2+, and BDCA3+ Dendritic Cells Are Differentially Subverted in Patients With Chronic HBV Infection

scientific article published on 04 February 2019

Control of hepatitis B virus replication by innate response of HepaRG cells.

scientific article published on January 2010

Corrigendum to "Toll-like receptor 3 downregulation is an escape mechanism from apoptosis during hepatocarcinogenesis" [J Hepatol 71 (2019) 763-772]

scientific article published on 25 November 2019

DNA methylation of hepatitis B virus (HBV) genome associated with the development of hepatocellular carcinoma and occult HBV infection

scientific article

Detection of the hepatitis B virus (HBV) covalently-closed-circular DNA (cccDNA) in mice transduced with a recombinant AAV-HBV vector

scientific article published on 11 July 2017

Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes.

scientific article published on 29 March 2018

Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells

scientific article

Early inhibition of hepatocyte innate responses by hepatitis B virus.

scientific article published on 24 July 2015

Effects of interferon, ribavirin, and iminosugar derivatives on cells persistently infected with noncytopathic bovine viral diarrhea virus

scientific article published on February 2004

Epidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus.

scientific article

Expression and functionality of Toll- and RIG-like receptors in HepaRG cells.

scientific article published on 2 July 2015

Fast Differentiation of HepaRG Cells Allowing Hepatitis B and Delta Virus Infections

scientific article published on 14 October 2020

Fitness and infectivity of drug-resistant and cross-resistant hepatitis B virus mutants: why and how is it studied?

scientific article published on January 2010

Genetic variability of hepatitis C virus in chronically infected patients with viral breakthrough during interferon-ribavirin therapy

scientific article published on September 2004

Genomic responses to hepatitis B virus (HBV) infection in primary human hepatocytes.

scientific article published on 2 November 2015

Going towards more relevant cell culture models to study the in vitro replication of serum-derived hepatitis C virus and virus/host cell interactions?

scientific article published on 3 November 2006

HBV infection and HCC: the 'dangerous liaisons'.

scientific article

HCV research 20 years after discovery: a summary of the 16th international symposium on hepatitis C virus and related viruses

scientific article published on 18 November 2009

HDV RNA replication is associated with HBV repression and interferon-stimulated genes induction in super-infected hepatocytes

scientific article

Hepatitis B Virus Blocks the CRE/CREB Complex and Prevents TLR9 Transcription and Function in Human B Cells

scholarly article by Issam Tout et al published 15 October 2018 in Journal of Immunology

Hepatitis B and hepatitis D virus infections in the Central African Republic, twenty-five years after a fulminant hepatitis outbreak, indicate continuing spread in asymptomatic young adults.

scientific article published on 26 April 2018

Hepatitis B virus Core protein nuclear interactome identifies SRSF10 as a host RNA-binding protein restricting HBV RNA production

scientific article published on 12 November 2020

Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection.

scientific article published on 2 March 2011

Hepatitis B virus evasion from cGAS sensing in human hepatocytes.

scientific article

Hepatitis B virus infection enhances susceptibility toward adeno-associated viral vector transduction in vitro and in vivo.

scientific article published on 30 April 2014

Hepatitis B virus replication in primary macaque hepatocytes: crossing the species barrier toward a new small primate model.

scientific article published in June 2010

Hepatitis B virus requires intact caveolin-1 function for productive infection in HepaRG cells

scientific article

Hepatitis B virus-induced modulation of liver macrophage function promotes hepatocyte infection

scientific article published on 23 July 2019

Hepatitis C virus fails to activate NF-κB signaling in plasmacytoid dendritic cells

scientific article published on 16 November 2011

Hepatitis delta virus: From biological and medical aspects to current and investigational therapeutic options

scientific article

Immune-modulators to combat hepatitis B virus infection: From IFN-α to novel investigational immunotherapeutic strategies

scientific article published on 12 August 2015

In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2',3'-dideoxy-3'-fluoroguanosine.

scientific article published on March 2006

Inhibition of hepatitis C virus replication by semi-synthetic derivatives of glycopeptide antibiotics

scientific article published on 24 March 2011

Initiation of hepatitis B virus genome replication and production of infectious virus following delivery in HepG2 cells by novel recombinant baculovirus vector

scientific article

Innate antiviral immune responses to hepatitis B virus.

scientific article published on 05 July 2010

Innate response to hepatitis B virus infection: Observations challenging the concept of a stealth virus

article

Interaction between TLR9-CpG-ODNs and HBV virions leads to entry inhibition in hepatocytes and reduction of IFNα production by pDC.

scientific article published on 12 February 2018

Interplay between hepatitis B virus and TLR2-mediated innate immune responses: Can restoration of TLR2 functions be a new therapeutic option? ⬇️

scientific article published on June 21, 2012

Interplay between the Hepatitis B Virus and Innate Immunity: From an Understanding to the Development of Therapeutic Concepts.

scientific article

Intrahepatic innate immune response pathways are downregulated in untreated chronic hepatitis B.

scientific article published on 30 December 2016

Liver macrophages: Friend or foe during hepatitis B infection?

scientific article published on 09 June 2018

Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis

scientific article (publication date: March 2013)

Management and prevention of drug resistance in chronic hepatitis B.

scientific article published on January 2009

Mechanism of action of ribavirin in anti-HCV regimens: new insights for an age-old question? ⬇️

scientific article published on May 9, 2013

Mechanisms behind TB, HBV, and HIV chronic infections.

scientific article published on 12 September 2017

Meeting report: 31st International Conference on Antiviral Research

scientific article published on 04 August 2018

NOD1 Participates in the Innate Immune Response Triggered by Hepatitis C Virus Polymerase

scientific article published on 20 April 2016

New antiviral targets for innovative treatment concepts for hepatitis B virus and hepatitis delta virus

scientific article published on April 2016

New treatments to reach functional cure: Virological approaches.

scientific article published on 22 May 2017

Novel Potent Capsid Assembly Modulators Regulate Multiple Steps of the Hepatitis B Virus Life Cycle

scientific article published on 24 September 2018

Novel targets for hepatitis B virus therapy

scientific article published on January 2017

Persistence of the hepatitis B virus covalently closed circular DNA in HepaRG human hepatocyte-like cells.

scientific article

Polo-like-kinase 1 is a proviral host-factor for hepatitis B virus replication

scientific article published on 26 April 2017

RNA helicase DEAD box protein 5 regulates Polycomb repressive complex 2/Hox transcript antisense intergenic RNA function in hepatitis B virus infection and hepatocarcinogenesis

scientific article published on 23 June 2016

Receptor complementation and mutagenesis reveal SR-BI as an essential HCV entry factor and functionally imply its intra- and extra-cellular domains

scientific article published on 20 February 2009

Reciprocal antagonism between the netrin-1 receptor uncoordinated-phenotype-5A (UNC5A) and the hepatitis C virus

scientific article published on 07 August 2017

Reduction of the infectivity of hepatitis C virus pseudoparticles by incorporation of misfolded glycoproteins induced by glucosidase inhibitors

scientific article published on April 2007

Resistance of human hepatitis B virus to reverse transcriptase inhibitors: from genotypic to phenotypic testing.

scientific article

Ribavirin restores IFNα responsiveness in HCV-infected livers by epigenetic remodelling at interferon stimulated genes

scientific article published on 16 June 2015

Role of disulfide bond formation in the folding and assembly of the envelope glycoproteins of a pestivirus

scientific article published on August 2002

Short peptide nucleic acids (PNA) inhibit hepatitis C virus internal ribosome entry site (IRES) dependent translation in vitro.

scientific article

Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

scientific article

Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development

scientific article published on July 2009

Study of the mechanism of antiviral action of iminosugar derivatives against bovine viral diarrhea virus

scientific article

Susceptibility to antivirals of a human HBV strain with mutations conferring resistance to both lamivudine and adefovir.

scientific article

Synthesis of 1,2,3-triazolo-carbanucleoside analogues of ribavirin targeting an HCV in replicon.

scientific article published in August 2003

Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: antiviral activity and cellular toxicity.

scientific article published on November 2005

Targeting innate immunity: a new step in the development of combination therapy for chronic hepatitis B.

scientific article published in June 2013

Temporal expression of the AcMNPV lef-4 gene and subcellular localization of the protein.

scientific article

The HepaRG cell line: biological properties and relevance as a tool for cell biology, drug metabolism, and virology studies.

scientific article published on January 2010

The diverse functions of the hepatitis B core/capsid protein (HBc) in the viral life cycle: Implications for the development of HBc-targeting antivirals.

scientific article published on 25 November 2017

Toll-Like Receptor 7 Agonist GS-9620 Induces Prolonged Inhibition of HBV via a Type I Interferon-Dependent Mechanism

scientific article published on 13 December 2017

Toll-like receptor 3 downregulation is an escape mechanism from apoptosis during hepatocarcinogenesis

scientific article published on 18 June 2019

Towards an HBV cure: state-of-the-art and unresolved questions--report of the ANRS workshop on HBV cure.

scientific article

Treatment of hepatitis B virus-infected cells with alpha-glucosidase inhibitors results in production of virions with altered molecular composition and infectivity.

scientific article published on 22 May 2007

Very-low-density lipoprotein (VLDL)-producing and hepatitis C virus-replicating HepG2 cells secrete no more lipoviroparticles than VLDL-deficient Huh7.5 cells.

scientific article published on 20 February 2013

Who Defends the Stem Cell's Citadel?

scientific article published in March 2018

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