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List of works by Paul Jolicoeur

Activation of p21-activated kinase 2 and its association with Nef are conserved in murine cells but are not sufficient to induce an AIDS-like disease in CD4C/HIV transgenic mice

scientific article

Adult AIDS-like disease in a novel inducible human immunodeficiency virus type 1 Nef transgenic mouse model: CD4+ T-cell activation is Nef dependent and can occur in the absence of lymphophenia

scientific article published on 09 September 2009

Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrations

scientific article

Altered CD4+ T cell phenotype and function determine the susceptibility to mucosal candidiasis in transgenic mice expressing HIV-1

scientific article published on 01 July 2006

Altered Immune Response Differentially Enhances Susceptibility to Cryptococcus neoformans and Cryptococcus gattii Infection in Mice Expressing the HIV-1 Transgene ⬇️

scientific article published on January 22, 2013

Bone degradation machinery of osteoclasts: An HIV-1 target that contributes to bone loss

scientific article published on 20 February 2018

CD4+ T cells from CD4C/HIVNef transgenic mice show enhanced activation in vivo with impaired proliferation in vitro but are dispensable for the development of a severe AIDS-like organ disease

scientific article published on May 2004

CD8+ T cells but not polymorphonuclear leukocytes are required to limit chronic oral carriage of Candida albicans in transgenic mice expressing human immunodeficiency virus type 1.

scientific article

Cardiac disease in transgenic mice expressing human immunodeficiency virus-1 nef in cells of the immune system

scientific article published on July 2002

Cardiac repolarization is prolonged in CD4C/HIV transgenic mice

scientific article published on 18 May 2007

Characterization of a tissue-specific CDP/Cux isoform, p75, activated in breast tumor cells

scientific article published on November 2002

Cyclin D1-Dependent Induction of Luminal Inflammatory Breast Tumors by Activated Notch3 ⬇️

scientific article published on August 8, 2013

Defective IL-17- and IL-22-dependent mucosal host response to Candida albicans determines susceptibility to oral candidiasis in mice expressing the HIV-1 transgene

scientific article

Evidence for a pathogenic determinant in HIV-1 Nef involved in B cell dysfunction in HIV/AIDS.

scientific article published on July 2008

Expression of HIV-1 genes in podocytes alone can lead to the full spectrum of HIV-1-associated nephropathy

scientific article published in September 2005

Expression of constitutively active Notch1 in male genital tracts results in ectopic growth and blockage of efferent ducts, epididymal hyperplasia and sterility.

scientific article published on 14 September 2006

Expression of simian immunodeficiency virus nef in immune cells of transgenic mice leads to a severe AIDS-like disease

scientific article

Fine allelotyping of Erbb2-induced mammary tumors in mice reveals multiple discontinuous candidate regions of tumor-suppressor loci.

scientific article

Fv-1 function

journal article; published in Nature, 1976-06

Genetic control of myeloproliferation in BXH-2 mice

scientific article published on 20 November 2003

HIV Nef expression favors the relative preservation of CD4+ T regulatory cells that retain some important suppressive functions

scientific article published on 24 January 2014

HIV-1 Nef Disrupts Maturation of CD4+ T Cells through CD4/Lck Modulation ⬇️

scientific article published on September 8, 2010

HIV-1 Nef mutations abrogating downregulation of CD4 affect other Nef functions and show reduced pathogenicity in transgenic mice

scientific article published on 28 November 2005

HIV-1 genes vpr and nef synergistically damage podocytes, leading to glomerulosclerosis

scientific article published on 20 September 2006

HIV-1 reprograms the migration of macrophages

scientific article published on 19 December 2014

HIV-Nef Protein Persists in the Lungs of Aviremic HIV Patients and Induces Endothelial Cell Death

article

HIV-Nef Protein Persists in the Lungs of Aviremic Patients with HIV and Induces Endothelial Cell Death

scientific article published on 15 October 2018

HIV-Nef Protein Transfer to Endothelial Cells Requires Rac1 Activation and Leads to Endothelial Dysfunction Implications for Statin Treatment in HIV Patients

scientific article published on 27 August 2019

IKK2 inhibitor alleviates kidney and wasting diseases in a murine model of human AIDS

scientific article

Immunopathogenesis of oropharyngeal candidiasis in human immunodeficiency virus infection.

scientific article published in October 2004

In vivo mutational analysis of the N-terminal region of HIV-1 Nef reveals critical motifs for the development of an AIDS-like disease in CD4C/HIV transgenic mice

scientific article published in October 2004

Induction of rat liver tyrosine aminotransferase by dibutyryl cyclic AMP and its inhibition by actinomycin D and alpha-Amanitin

scientific article published on 01 September 1971

Inhibition of the Nef regulatory protein of HIV-1 by a single-domain antibody.

scientific article published on 3 February 2011

Macrophage-mediated responses to Candida albicans in mice expressing the human immunodeficiency virus type 1 transgene

scientific article published on 29 June 2009

Mucosal candidiasis in transgenic mice expressing human immunodeficiency virus type 1.

scientific article published on 21 March 2002

No detectable XMRV in subjects with chronic fatigue syndrome from Quebec ⬇️

scientific article published on September 16, 2011

Normal development and function but impaired memory phenotype of CD8+ T cells in transgenic mice expressing HIV-1 Nef in its natural target cells ⬇️

scientific article published on February 22, 2013

Oligodendrocyte-specific expression of human immunodeficiency virus type 1 Nef in transgenic mice leads to vacuolar myelopathy and alters oligodendrocyte phenotype in vitro

scientific article published on November 2003

Oral mucosal cell response to Candida albicans in transgenic mice expressing HIV-1

scientific article published on 01 January 2009

Oropharyngeal Candidiasis in HIV Infection: Analysis of Impaired Mucosal Immune Response to Candida albicans in Mice Expressing the HIV-1 Transgene

scientific article

Overexpression of Notch1 ectodomain in myeloid cells induces vascular malformations through a paracrine pathway

scientific article published on January 2007

Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors

scientific article

Primary human immunodeficiency virus type 1 nef alleles show major differences in pathogenicity in transgenic mice

scientific article published on 21 February 2007

Protection against murine leukemia virus-induced spongiform myeloencephalopathy in mice overexpressing Bcl-2 but not in mice deficient for interleukin-6, inducible nitric oxide synthetase, ICE, Fas, Fas ligand, or TNF-R1 genes

scientific article

Selective expression of human immunodeficiency virus Nef in specific immune cell populations of transgenic mice is associated with distinct AIDS-like phenotypes

scientific article published on 15 July 2009

Structurally distinct ligand-binding or ligand-independent Notch1 mutants are leukemogenic but affect thymocyte development, apoptosis, and metastasis differently

scientific article published on 01 August 2006

The AIDS-like disease of CD4C/human immunodeficiency virus transgenic mice is associated with accumulation of immature CD11bHi dendritic cells

scientific article published on November 2003

The CD4C/HIVNef Transgenic Model of AIDS ⬇️

scientific article published on 01 October 2011

The Nef-mediated AIDS-like disease of CD4C/human immunodeficiency virus transgenic mice is associated with increased Fas/FasL expression on T cells and T-cell death but is not prevented in Fas-, FasL-, tumor necrosis factor receptor 1-, or interleuk

scientific article

Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction

scientific article

Xenotropic and Other Murine Leukemia Virus-Related Viruses in Humans ⬇️

scientific article published on December 20, 2011

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