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List of works by Paolo Giovanni Casali

(Neo)adjuvant treatment in localised soft tissue sarcoma: The unsolved affair

scientific article published on 17 November 2016

2018 ESMO Sarcoma and GIST Symposium: 'take-home messages' in soft tissue sarcoma.

scientific article published on 28 June 2018

A Novel Tyrosine-Kinase Selective Inhibitor, Sunitinib, Induces Transient Hypothyroidism by Blocking Iodine Uptake

scientific article published on 26 June 2007

A new mutation in the KIT ATP pocket causes acquired resistance to imatinib in a gastrointestinal stromal tumor patient

scientific article

A phase 2 trial of imatinib mesylate in patients with recurrent nonresectable chondrosarcomas expressing platelet-derived growth factor receptor-α or -β: An Italian Sarcoma Group study.

scientific article

A phase I study of single-agent nilotinib or in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors

scientific article

A phase II randomised (calibrated design) study on the activity of the single-agent trabectedin in metastatic or locally relapsed uterine leiomyosarcoma.

scientific article published on 30 July 2018

A phase II trial of sorafenib in relapsed and unresectable high-grade osteosarcoma after failure of standard multimodal therapy: an Italian Sarcoma Group study ⬇️

scientific article published on April 28, 2011

A retrospective analysis of antitumour activity with trabectedin in translocation-related sarcomas

scientific article

A role for DRAK2 in the germinal center reaction and the antibody response

scientific article

Absence of progression as assessed by response evaluation criteria in solid tumors predicts survival in advanced GI stromal tumors treated with imatinib mesylate: the intergroup EORTC-ISG-AGITG phase III trial

scientific article

Abstract LB-295: Detection of oncogenic kinase mutations in circulating plasma DNA and correlation with clinical benefit in the phase III GRID study of regorafenibvsplacebo in TKI-refractory metastatic GIST

article

Activity of Pazopanib and Trabectedin in Advanced Alveolar Soft Part Sarcoma

scientific article

Activity of anthracycline- and ifosfamide-based chemotherapy in a series of patients affected by advanced myxofibrosarcoma

scientific article published on 22 August 2017

Activity of axitinib in progressive advanced solitary fibrous tumour: Results from an exploratory, investigator-driven phase 2 clinical study

scientific article published on 05 December 2018

Activity of sirolimus in patients with progressive epithelioid hemangioendothelioma: A case-series analysis within the Italian rare cancer network

scientific article published on 27 October 2020

Activity of sunitinib in extraskeletal myxoid chondrosarcoma

scientific article published on 02 April 2014

Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment.

scientific article published on 5 September 2016

Adaptive immune contexture at the tumour site and downmodulation of circulating myeloid-derived suppressor cells in the response of solitary fibrous tumour patients to anti-angiogenic therapy

scientific article

Addition of anti-estrogen treatment in patients with malignant PEComa progressing to mTOR inhibitors

scientific article published on 30 June 2020

Adequate Local Control in High-Risk Soft Tissue Sarcoma of the Extremity Treated with Surgery Alone at a Reference Centre: Should Radiotherapy Still be a Standard?

scientific article published on 22 February 2018

Adjuvant Chemotherapy for Soft Tissue Sarcoma

scientific article published on 01 January 2015

Adjuvant Imatinib for GI Stromal Tumors: When and For How Long?

scientific article published on 7 December 2015

Adjuvant Therapy for High-Risk Soft Tissue Sarcoma in the Adult ⬇️

scientific article published on September 1, 2013

Adjuvant chemotherapy for soft tissue sarcoma

scientific article

Adjuvant therapy in primary GIST: state-of-the-art

scientific article

Adjuvant therapy of gastrointestinal stromal tumors (GIST).

scientific article published on September 2012

Adjuvant treatment of GIST with imatinib: solid ground or still quicksand? A comment on behalf of the EORTC Soft Tissue and Bone Sarcoma Group, the Italian Sarcoma Group, the NCRI Sarcoma Clinical Studies Group (UK), the Japanese Study Group on GIST

scientific article published on 13 March 2009

Advanced Extremity Soft Tissue Sarcoma: Prognostic Effect of Isolated Limb Perfusion in a Series of 88 Patients Treated at a Single Institution

scientific article published on 23 November 2006

Advances and controversies in the management of soft tissue sarcomas

scientific article

Aggressive Surgery in Retroperitoneal Soft Tissue Sarcoma Carried Out at High-Volume Centers is Safe and is Associated With Improved Local Control

scientific article published on 01 June 2010

Aggressive Surgical Policies in a Retrospectively Reviewed Single-Institution Case Series of Retroperitoneal Soft Tissue Sarcoma Patients

scientific article published on 01 December 2008

Alveolar soft part sarcoma: clinical presentation, treatment, and outcome in a series of 33 patients at a single institution.

scientific article

An ESMO-EORTC position paper on the EU clinical trials regulation and EMA's transparency policy: making European research more competitive again

scientific article published on 23 March 2015

Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas

scientific article published on 17 February 2010

Anthracycline, Gemcitabine, and Pazopanib in Epithelioid Sarcoma: A Multi-institutional Case Series

scientific article published on 13 September 2018

Anthracycline-based and gemcitabine-based chemotherapy in the adjuvant setting for stage I uterine leiomyosarcoma: a retrospective analysis at two reference centers

scientific article published on 28 August 2020

Anthracycline-based chemotherapy in extraskeletal myxoid chondrosarcoma: a retrospective study

scientific article published on 18 December 2013

Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells.

scientific article

BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway

scientific article

Best practices for the management of local-regional recurrent chordoma: a position paper by the Chordoma Global Consensus Group.

scientific article

Best practices for the management of thymic epithelial tumors: A position paper by the Italian collaborative group for ThYmic MalignanciEs (TYME)

article

Biosimilars: a position paper of the European Society for Medical Oncology, with particular reference to oncology prescribers

scientific article

CDX-2 expression in pseudomyxoma peritonei: a clinicopathological study of 42 cases

scientific article published on 01 October 2006

Cancer patients as 'experts' in defining quality of life domains. A multicentre survey by the Italian Group for the Evaluation of Outcomes in Oncology (IGEO).

scientific article

Career opportunities and benefits for young oncologists in the European Society for Medical Oncology (ESMO).

scientific article

Carney triad: case report and molecular analysis of gastric tumor

scientific article

Chordoma

scientific article published on 01 July 2007

Chordoma of the mobile spine and sacrum: a retrospective analysis of a series of patients surgically treated at two referral centers

scientific article published on 22 October 2009

Class switching and Myc translocation: how does DNA break?

scientific article

Clinical evaluation of continuous daily dosing of sunitinib malate in patients with advanced gastrointestinal stromal tumour after imatinib failure

scientific article

Combination of PPARγ Agonist Pioglitazone and Trabectedin Induce Adipocyte Differentiation to Overcome Trabectedin Resistance in Myxoid Liposarcomas

scientific article published on 03 September 2019

Combined modalities approach for localized adult extremity soft-tissue sarcoma

scientific article published on August 2007

Comparative Assessment of Antitumor Effects and Autophagy Induction as a Resistance Mechanism by Cytotoxics and EZH2 Inhibition in INI1-Negative Epithelioid Sarcoma Patient-Derived Xenograft

scientific article published on 19 July 2019

Complete longitudinal analyses of the randomized, placebo-controlled, phase III trial of sunitinib in patients with gastrointestinal stromal tumor following imatinib failure

scientific article

Completion surgery of residual disease after primary inadequate surgery of retroperitoneal sarcomas can salvage a selected subgroup of patients-A propensity score analysis

scientific article published on 16 December 2018

Consensus meeting for the management of gastrointestinal stromal tumors. Report of the GIST Consensus Conference of 20-21 March 2004, under the auspices of ESMO.

scientific article

Correction: Combination of PPARγ Agonist Pioglitazone and Trabectedin Induce Adipocyte Differentiation to Overcome Trabectedin Resistance in Myxoid Liposarcomas

scientific article published on 01 March 2020

Correction: Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin

scientific article published on 01 March 2020

Correlation between radiological assessment and histopathological diagnosis in retroperitoneal tumors: analysis of 291 consecutive patients at a tertiary reference sarcoma center.

scientific article published on 15 October 2014

Corrigendum to "Italian consensus conference on management of uterine sarcomas on behalf of S.I.G.O. (Societa' italiana di Ginecologia E Ostetricia)" [Eur J Canc. vol. 139 November (2020) Pages 149-168]

scientific article published on 19 December 2020

Crystal Structure of a Human Autoimmune Complex between IgM Rheumatoid Factor RF61 and IgG1 Fc Reveals a Novel Epitope and Evidence for Affinity Maturation

scientific article

Current status and unanswered questions on the use of Denosumab in giant cell tumor of bone

scientific article

Cytokeratin Immunoreactivity in 41 Cases of ES/PNET Confirmed by Molecular Diagnostic Studies

scientific article published on 01 February 2001

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

scientific article (publication date: September 2002)

Dacarbazine in solitary fibrous tumor: a case series analysis and preclinical evidence vis-a-vis temozolomide and antiangiogenics

scientific article published on 25 July 2013

Delivering precision medicine in oncology today and in future-the promise and challenges of personalised cancer medicine: a position paper by the European Society for Medical Oncology (ESMO).

scientific article

Denosumab treatment of inoperable or locally advanced giant cell tumor of bone - Multicenter analysis outside clinical trial

scientific article published on 31 March 2018

Dermatofibrosarcoma protuberans treated at a single institution: a surgical disease with a high cure rate

scientific article

Dermatofibrosarcoma protuberans-derived fibrosarcoma: clinical history, biological profile and sensitivity to imatinib.

scientific article

Descriptive epidemiology of sarcomas in Europe: report from the RARECARE project.

scientific article published on 15 October 2012

Desmoid-type fibromatosis and pregnancy: a multi-institutional analysis of recurrence and obstetric risk.

scientific article

Desmoid-type fibromatosis: a front-line conservative approach to select patients for surgical treatment.

scientific article

Development and external validation of a dynamic prognostic nomogram for primary extremity soft tissue sarcoma survivors

scientific article published on 22 November 2019

Development and external validation of two nomograms to predict overall survival and occurrence of distant metastases in adults after surgical resection of localised soft-tissue sarcomas of the extremities: a retrospective analysis

scientific article published on 5 April 2016

Development and validation of prognostic nomograms for metastatic gastrointestinal stromal tumour treated with imatinib

scientific article published on 19 March 2015

Diffuse malignant mesothelioma of the peritoneum

scientific article published on 01 November 2005

Do rare cancers deserve specific strategies for cancer research?

scientific article published in June 2010

ECCO Essential Requirements for Quality Cancer Care: Soft Tissue Sarcoma in Adults and Bone Sarcoma. A critical review

scientific article published on 08 December 2016

ERCC5/XPG, ERCC1, and BRCA1 gene status and clinical benefit of trabectedin in patients with soft tissue sarcoma

scientific article

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016

scientific article (publication date: 2016)

Efficacy and Biological Activity of Imatinib in Metastatic Dermatofibrosarcoma Protuberans (DFSP).

scientific article

Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial

scientific article

Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial

scientific article

Efficacy and safety of trabectedin as an early treatment for advanced or metastatic liposarcoma and leiomyosarcoma

scientific article published on 29 August 2013

Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study

scientific article published on July 2007

Emerging therapies for adult soft tissue sarcoma.

scientific article

Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions

scientific article

Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response

scientific article

Epithelioid peritoneal mesothelioma: a hybrid phenotype within a mesenchymal-epithelial/epithelial-mesenchymal transition framework

scientific article published on 26 September 2016

Epithelioid sarcoma: prognostic factors and survival in a series of patients treated at a single institution

scientific article published on 2 October 2007

Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin

scientific article published on 14 August 2019

Ethical issues in oncology practice: a qualitative study of stakeholders’ experiences and expectations

scientific article published in 2022

Etoposide, doxorubicin and cisplatin plus mitotane in the treatment of advanced adrenocortical carcinoma: a large prospective phase II trial

scientific article published in September 2005

Evaluating the effectiveness of clinical ethics committees: a systematic review

scientific article published on 21 November 2020

Evidence for PDGFRA, PDGFRB and KIT deregulation in an NSCLC patient.

scientific article published in January 2007

Evolution of Dermatofibrosarcoma Protuberans to DFSP-Derived Fibrosarcoma: An Event Marked by Epithelial-Mesenchymal Transition-like Process and 22q Loss

article

Ewing sarcoma of the small bowel: a study of seven cases, including one with the uncommonly reported EWSR1-FEV translocation

scientific article

Ewing's sarcoma of the bone: ESMO clinical recommendations for diagnosis, treatment and follow-up.

scientific article published on May 2009

Expression of ligand-activated KIT and platelet-derived growth factor receptor beta tyrosine kinase receptors in synovial sarcoma

scientific article published on February 2004

External validation of a multi-institutional retroperitoneal sarcoma nomogram

scientific article

Extraskeletal myxoid chondrosarcoma: tumor response to sunitinib

scientific article

Extremity Soft Tissue Sarcoma in a Series of Patients Treated at a Single Institution

scientific article published on 01 March 2010

Extremity Soft Tissue Sarcoma: Adding to the Prognostic Meaning of Local Failure

scientific article published on 28 January 2007

Feasibility of Preoperative Chemotherapy With or Without Radiation Therapy in Localized Soft Tissue Sarcomas of Limbs and Superficial Trunk in the Italian Sarcoma Group/Grupo Español de Investigación en Sarcomas Randomized Clinical Trial: Three Vers

scientific article

Fluorescence in situ hybridization analysis and immunophenotyping of c-Kit/PDGFRA and Bcl-2 expression in gastrointestinal stromal tumors.

scientific article

Folate-related polymorphisms in gastrointestinal stromal tumours: susceptibility and correlation with tumour characteristics and clinical outcome

scientific article published on 17 September 2014

Frontline extended surgery is associated with improved survival in retroperitoneal low- to intermediate-grade soft tissue sarcomas.

scientific article published on 16 July 2011

Functional analyses and molecular modeling of two c-Kit mutations responsible for imatinib secondary resistance in GIST patients

article

Gain of FGF4 is a frequent event in KIT/PDGFRA/SDH/RAS-P WT GIST

scientific article published on 16 April 2019

Gastrointestinal stromal tumors: should they be treated with the same systemic chemotherapy as other soft tissue sarcomas?

scientific article

Gastrointestinal stromal tumours: ESMO clinical recommendations for diagnosis, treatment and follow-up.

scientific article published on May 2009

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published in October 2018

Gemcitabine in advanced angiosarcoma: a retrospective case series analysis from the Italian Rare Cancer Network

article

Genome-Wide Analysis Identifies MEN1 and MAX Mutations and a Neuroendocrine-Like Molecular Heterogeneity in Quadruple WT GIST.

scientific article published on 27 January 2017

Global cancer control: responding to the growing burden, rising costs and inequalities in access.

scientific article

Growth modulation index as metric of clinical benefit assessment among advanced soft tissue sarcoma patients receiving trabectedin as a salvage therapy.

scientific article

Guidelines for time-to-event end point definitions in sarcomas and gastrointestinal stromal tumors (GIST) trials: results of the DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer trials)†.

scientific article

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma

scientific article published on 6 April 2017

Head and neck soft tissue sarcomas: prognostic factors and outcome in a series of patients treated at a single institution

scientific article

High-Dose Ifosfamide Chemotherapy in a Series of Patients Affected by Myxoid Liposarcoma.

scientific article published on 30 August 2017

High-dose continuous-infusion ifosfamide in advanced well-differentiated/dedifferentiated liposarcoma

scientific article

High-grade soft-tissue sarcomas: tumor response assessment--pilot study to assess the correlation between radiologic and pathologic response by using RECIST and Choi criteria

scientific article published on 4 March 2009

High-risk soft tissue sarcomas treated with perioperative chemotherapy: Improving prognostic classification in a randomised clinical trial

scientific article published on 21 February 2018

Histology- and non-histology-driven therapy for treatment of soft tissue sarcomas

scientific article published on 01 September 2012

Histology-specific nomogram for primary retroperitoneal soft tissue sarcoma

scientific article published in May 2010

Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial

scientific article

Hope in cancer patients: the relational domain as a crucial factor

scientific article

Hormonal manipulation with toremifene in sporadic desmoid-type fibromatosis.

scientific article published on 18 November 2015

How a Clinical Trial Unit can improve independent clinical research in rare tumors: the Italian Sarcoma Group experience.

scientific article published on 28 February 2017

HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation

scientific article

Human equilibrative nucleoside transporter 1 gene expression is associated with gemcitabine efficacy in advanced leiomyosarcoma and angiosarcoma

scientific article published on 22 June 2017

Identification of SRF-E2F1 fusion transcript in EWSR-negative myoepithelioma of the soft tissue

scientific article published on 17 May 2017

Identification of a gene expression driven progression pathway in myxoid liposarcoma

scientific article

Identification of an Actionable Mutation of KIT in a Case of Extraskeletal Myxoid Chondrosarcoma

scientific article published on 23 June 2018

Imatinib and everolimus in patients with progressing advanced chordoma: A phase 2 clinical study

scientific article published on 14 September 2018

Imatinib does not induce cardiac left ventricular failure in gastrointestinal stromal tumours patients: Analyis of EORTC-ISG-AGITG study 62005

Imatinib dose escalation versus sunitinib as a second line treatment in KIT exon 11 mutated GIST: a retrospective analysis

scientific article published on 24 September 2015

Imatinib in advanced chordoma: A retrospective case series analysis

scientific article published on 14 August 2015

Imatinib mesylate in chordoma

scientific article

Imatinib rechallenge in patients with advanced gastrointestinal stromal tumors following progression with imatinib, sunitinib and regorafenib

scientific article published on 29 August 2018

Imatinib response in two GIST patients carrying two hitherto functionally uncharacterized PDGFRA mutations: an imaging, biochemical and molecular modeling study

scientific article published in February 2011

Impact of chemotherapy in uterine sarcoma (UtS): review of 13 clinical trials from the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) involving advanced/metastatic UtS compared to other soft tissue sarcoma (STS) patients treated with first line ch

scientific article published on 18 May 2016

Impact of perioperative chemotherapy and radiotherapy in patients with primary extremity soft tissue sarcoma: retrospective analysis across major histological subtypes and major reference centres

scientific article published on 29 October 2018

Improving methodology to go beyond histology in rare cancers ⬇️

scientific article published on March 8, 2013

Improving treatment results with reference centres for rare cancers: where do we stand?

scientific article published on 3 April 2017

In Reply

scientific article published on 12 September 2020

Initial and late resistance to imatinib in advanced gastrointestinal stromal tumors are predicted by different prognostic factors: a European Organisation for Research and Treatment of Cancer-Italian Sarcoma Group-Australasian Gastrointestinal Trial

scientific article published in August 2005

International collaborations in cancer control and the Third International Cancer Control Congress.

scientific article published in September 2009

Intraperitoneal Invasion of Retroperitoneal Sarcomas: A Risk Factor for Dismal Prognosis

scientific article published on 16 July 2019

Is autophagy rather than apoptosis the regression driver in imatinib-treated gastrointestinal stromal tumors?

scientific article published on December 2008

KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours

scientific article

KIT, PDGFRA, and BRAF mutational spectrum impacts on the natural history of imatinib-naive localized GIST: a population-based study

scientific article published on July 2015

Leiomyosarcoma and sarcoma with myogenic differentiation

scientific article published on 19 April 2012

Localised thoracic sarcomas: outcome improvement over time at a single institution

scientific article published on 14 May 2013

Long-term Efficacy of Methotrexate Plus Vinblastine/Vinorelbine in a Large Series of Patients Affected by Desmoid-Type Fibromatosis.

scientific article published on March 2017

Long-term Follow-up and Post-relapse Outcome of Patients with Localized Retroperitoneal Sarcoma Treated in the Italian Sarcoma Group-Soft Tissue Sarcoma (ISG-STS) Protocol 0303.

scientific article published on 17 October 2017

Long-term follow-up of patients with GIST undergoing metastasectomy in the era of imatinib -- analysis of prognostic factors (EORTC-STBSG collaborative study).

scientific article published on 15 January 2014

Long-term morbidity after multivisceral resection for retroperitoneal sarcoma

scientific article published on 3 June 2015

MRP1 overexpression determines poor prognosis in prospectively treated patients with localized high-risk soft tissue sarcoma of limbs and trunk wall: an ISG/GEIS study.

scientific article

Malignant peripheral nerve sheath tumors

scientific article published on 01 September 2006

Management of Gastrointestinal Stromal Tumour: Current Practices and Visions for the Future

scientific article published on 26 February 2015

Management of complicated tumor response to tyrosine-kinase inhibitors in gastrointestinal stromal tumors

scientific article published on 07 May 2019

Median sternotomy and multiple lung resections for metastatic sarcomas

article

Medical oncology: the long-awaited prize of recognition ⬇️

scientific article published on June 30, 2011

Melan-A/MART-1 immunity in a EWS-ATF1 translocated clear cell sarcoma patient treated with sunitinib: a case report

scientific article

Mode of action of trabectedin in myxoid liposarcomas.

scientific article published on 11 November 2013

Molecular and biochemical analyses of platelet-derived growth factor receptor (PDGFR) B, PDGFRA, and KIT receptors in chordomas

scientific article published in December 2006

Molecular and clinicopathologic characterization of gastrointestinal stromal tumors (GISTs) of small size

scientific article published in October 2010

Morcellation worsens survival outcomes in patients with undiagnosed uterine leiomyosarcomas: A retrospective MITO group study.

scientific article published on 4 November 2016

Myogenic Differentiation and Histologic Grading Are Major Prognostic Determinants in Retroperitoneal Liposarcoma

scientific article published on 01 March 2015

Myxofibrosarcoma: Prognostic Factors and Survival in a Series of Patients Treated at a Single Institution

scientific article published on 28 September 2010

Myxoid liposarcoma and the mammalian target of rapamycin pathway

scientific article published on July 2013

Myxoid/round cell and pleomorphic liposarcomas: prognostic factors and survival in a series of patients treated at a single institution

scientific article

NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST)--update of the NCCN clinical practice guidelines.

scientific article published on July 2007

NR4A3 fusion proteins trigger an axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas

scientific article published on 14 May 2019

Natural history of imatinib-naive GISTs: a retrospective analysis of 929 cases with long-term follow-up and development of a survival nomogram based on mitotic index and size as continuous variables

scientific article

Neoadjuvant Chemotherapy in High-Risk Soft Tissue Sarcomas: Final Results of a Randomized Trial From Italian (ISG), Spanish (GEIS), French (FSG), and Polish (PSG) Sarcoma Groups

scientific article published on 18 May 2020

Neoadjuvant imatinib in locally advanced gastrointestinal stromal tumors (GIST): the EORTC STBSG experience

scientific article published on 13 June 2013

Neoadjuvant treatment: a novel standard?

scientific article

Networking in rare cancers: What was done, what's next

scientific article published on 12 April 2018

Nilotinib in locally advanced pigmented villonodular synovitis: a multicentre, open-label, single-arm, phase 2 trial

scientific article published on 20 March 2018

Novel models of myxoid liposarcoma xenografts mimicking the biological and pharmacologic features of human tumors.

scientific article published on 20 August 2010

Outcome of patients with advanced gastro-intestinal stromal tumours crossing over to a daily imatinib dose of 800 mg after progression on 400 mg.

scientific article

Outcome of patients with platelet-derived growth factor receptor alpha-mutated gastrointestinal stromal tumors in the tyrosine kinase inhibitor era.

scientific article

PDGFRalpha, PDGFRbeta and KIT expression/activation in conventional chondrosarcoma.

scientific article published on April 2006

PML down-regulation in soft tissue sarcomas

scientific article published in September 2010

PML expression in soft tissue sarcoma: Prognostic and predictive value in alkylating agents/antracycline-based first line therapy

scientific article published on 01 April 2012

Patient-derived solitary fibrous tumour xenografts predict high sensitivity to doxorubicin/dacarbazine combination confirmed in the clinic and highlight the potential effectiveness of trabectedin or eribulin against this tumour.

scientific article published on 8 March 2017

Patterns of care, prognosis, and survival in patients with metastatic gastrointestinal stromal tumors (GIST) refractory to first-line imatinib and second-line sunitinib

scientific article published on 8 November 2011

Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial

scientific article

Pazopanib for treatment of advanced extraskeletal myxoid chondrosarcoma: a multicentre, single-arm, phase 2 trial

scientific article published on 19 July 2019

Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial

scientific article published on 18 December 2018

Pazopanib for treatment of typical solitary fibrous tumours: a multicentre, single-arm, phase 2 trial

scientific article published on 14 February 2020

Peritoneal mesothelioma treated by induction chemotherapy, cytoreductive surgery, and intraperitoneal hyperthermic perfusion

scientific article

Personalization of regorafenib treatment in metastatic gastrointestinal stromal tumours in real-life clinical practice

scientific article published on 19 December 2017

Personalizing the Approach to Retroperitoneal Soft Tissue Sarcoma: Histology-specific Patterns of Failure and Postrelapse Outcome after Primary Extended Resection

scientific article published on 10 October 2014

Pharmacology and Clinical Toxicity of 4'-Iodo-4'-deoxydoxorubicin: An Example of Successful Application of Pharmacokinetics to Dose Escalation in Phase I Trials

article

Phase II study of imatinib in advanced chordoma

scientific article published on 13 February 2012

Phase II, open-label study of PTK787/ZK222584 for the treatment of metastatic gastrointestinal stromal tumors resistant to imatinib mesylate

scientific article published on 14 August 2007

Policy statement on multidisciplinary cancer care

scientific article published on 06 December 2013

Polymorphisms in OCTN1 and OCTN2 transporters genes are associated with prolonged time to progression in unresectable gastrointestinal stromal tumours treated with imatinib therapy

scientific article published on 2 November 2012

Post-imatinib surgery in advanced/metastatic GIST: is it worthwhile in all patients?

scientific article published on 23 July 2009

Post-relapse outcomes after primary extended resection of retroperitoneal sarcoma: A report from the Trans-Atlantic RPS Working Group.

scientific article published on 02 February 2017

Postoperative Morbidity After Radical Resection of Primary Retroperitoneal Sarcoma: A Report From the Transatlantic RPS Working Group.

scientific article published on 07 April 2017

Postoperative radiotherapy for synovial sarcoma of the head and neck during pregnancy: clinical and technical management and fetal dose estimates

scientific article published in January 2007

Preclinical and clinical evidence of activity of pazopanib in solitary fibrous tumour

scientific article published on 27 September 2014

Predicting toxicities for patients with advanced gastrointestinal stromal tumours treated with imatinib: A study of the European Organisation for Research and Treatment of Cancer, the Italian Sarcoma Group, and the Australasian Gastro-Intestinal Tria

article

Predictive impact of DNA repair functionality on clinical outcome of advanced sarcoma patients treated with trabectedin: a retrospective multicentric study

scientific article

Preoperative chemo-radiation therapy for localised retroperitoneal sarcoma: a phase I-II study from the Italian Sarcoma Group.

scientific article

Preoperative imatinib mesylate for unresectable or locally advanced primary gastrointestinal stromal tumors (GIST).

scientific article

Primary extremity soft tissue sarcomas: outcome improvement over time at a single institution

scientific article published on 17 January 2011

Prognostic Analysis of Clinicopathologic Factors in 49 Patients With Diffuse Malignant Peritoneal Mesothelioma Treated With Cytoreductive Surgery and Intraperitoneal Hyperthermic Perfusion

scientific article published on 18 January 2006

Prognostic Effect of Re-Excision in Adult Soft Tissue Sarcoma of the Extremity

scientific article published on 01 January 2006

Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: randomised trial

scientific article

Prolonged activity and toxicity of sirolimus in a patient with metastatic renal perivascular epithelioid cell tumor: a case report and literature review

article

QUOROM and the search for an updated 'clinical method' in the era of evidence-based medicine

scientific article published in August 2000

Quality of Surgery and Outcome in Localized Gastrointestinal Stromal Tumors Treated Within an International Intergroup Randomized Clinical Trial of Adjuvant Imatinib

scientific article published on 01 April 2020

Quality of life assessment and clinical decision-making*

scientific article published on 01 December 1997

Quality of surgery and neoadjuvant combined therapy in the ISG-GEIS trial on soft tissue sarcomas of limbs and trunk wall.

scientific article published on 30 October 2012

Quality of surgery and outcome in extra-abdominal aggressive fibromatosis: a series of patients surgically treated at a single institution.

scientific article

Quality of surgery and surgical reporting for patients with primary gastrointestinal stromal tumours participating in the EORTC STBSG 62024 adjuvant imatinib study

scientific article published on 31 August 2019

Radiomic analysis of soft tissues sarcomas can distinguish intermediate from high-grade lesions.

scientific article

Rare Cancers Europe (RCE) methodological recommendations for clinical studies in rare cancers: a European consensus position paper.

scientific article

Rare cancers are not so rare: The rare cancer burden in Europe ⬇️

scientific article published on October 25, 2011

Rare cancers: work in progress in Europe

scientific article published on 01 April 2014

Receptor tyrosine kinase pathway analysis sheds light on similarities between clear-cell sarcoma and metastatic melanoma.

scientific article

Rechallenge of denosumab in jaw osteonecrosis of patients with unresectable giant cell tumour of bone: a case series analysis and literature review

scientific article published on 01 July 2020

Regulation of Aicda expression and AID activity

scientific article

Regulation of B Cell Differentiation by Intracellular Membrane-Associated Proteins and microRNAs: Role in the Antibody Response

scientific article

Regulation of aicda expression and AID activity: relevance to somatic hypermutation and class switch DNA recombination

scientific article

Resection of Uninvolved Adjacent Organs Can Be Part of Surgery for Retroperitoneal Soft Tissue Sarcoma

Resection of uninvolved adjacent organs can be part of surgery for retroperitoneal soft tissue sarcoma

scientific article published on 09 March 2009

Response of conventional chondrosarcoma to gemcitabine alone: a case report

scientific article

Response to chemotherapy of solitary fibrous tumour: A retrospective study

scientific article published on 06 April 2013

Response to imatinib in villonodular pigmented synovitis (PVNS) resistant to nilotinib

scientific article published on 13 May 2013

Response to imatinib plus sirolimus in advanced chordoma.

scientific article published in July 2009

Response to isolated limb perfusion and chemotherapy with epirubicin plus ifosfamide in a metastatic malignant ossifying fibromyxoid tumor.

scientific article published on 28 December 2017

Response to sunitinib malate in advanced alveolar soft part sarcoma

scientific article

Retroperitoneal soft tissue sarcomas: patterns of recurrence in 167 patients treated at a single institution.

scientific article published in June 2004

Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution

scientific article

Risks of the new EU Data Protection Regulation: an ESMO position paper endorsed by the European oncology community.

scientific article published in August 2014

Role of Chemotherapy, VEGFR Inhibitors, and mTOR Inhibitors in Advanced Perivascular Epithelioid Cell Tumors (PEComas)

scientific article published on 19 June 2019

Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

scientific article published on 01 February 2013

START: a European state-of-the-art on-line instrument for clinical oncologists.

scientific article

SYT-SSX fusion genes and prognosis in synovial sarcoma.

scientific article published on November 2001

Sacral Chordoma: Long-term Outcome of a Large Series of Patients Surgically Treated at Two Reference Centers.

scientific article published in June 2016

Selective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elements

scientific article (publication date: 20 June 2003)

Short, Full-Dose Adjuvant Chemotherapy in High-Risk Adult Soft Tissue Sarcomas: A Randomized Clinical Trial From the Italian Sarcoma Group and the Spanish Sarcoma Group

article

Short, full-dose adjuvant chemotherapy (CT) in high-risk adult soft tissue sarcomas (STS): long-term follow-up of a randomized clinical trial from the Italian Sarcoma Group and the Spanish Sarcoma Group

scientific article published on 11 October 2016

Shortages of inexpensive essential medicines

scientific article published on 18 April 2019

Sirolimus in Advanced Epithelioid Hemangioendothelioma: A Retrospective Case-Series Analysis from the Italian Rare Cancer Network Database.

scientific article published on 22 June 2016

Soft tissue sarcomas: ESMO clinical recommendations for diagnosis, treatment and follow-up

scientific article published on May 2009

Solitary fibrous tumor of all sites: outcome of late recurrences in 14 patients.

scientific article published on 3 April 2013

Solitary fibrous tumour presenting with a single bone metastasis: report of six cases and literature review

scientific article

Sorafenib and everolimus for patients with unresectable high-grade osteosarcoma progressing after standard treatment: a non-randomised phase 2 clinical trial.

scientific article

Sporadic desmoid-type fibromatosis: a stepwise approach to a non-metastasising neoplasm--a position paper from the Italian and the French Sarcoma Group

scientific article

Sporadic extra abdominal wall desmoid-type fibromatosis: surgical resection can be safely limited to a minority of patients.

scientific article

Status of Surgical Margins and Prognosis in Adult Soft Tissue Sarcomas of the Extremities: A Series of Patients Treated at a Single Institution

scientific article published on 01 January 2005

Steroid premedication markedly reduces liver and bone marrow toxicity of trabectedin in advanced sarcoma.

scientific article

Successes and limitations of targeted cancer therapy in gastrointestinal stromal tumors

scientific article published on 17 February 2014

Sunitinib malate and figitumumab in solitary fibrous tumor: patterns and molecular bases of tumor response

scientific article

Sunitinib malate in solitary fibrous tumor (SFT) ⬇️

scientific article published on June 17, 2012

Surgery of residual disease following molecular-targeted therapy with imatinib mesylate in advanced/metastatic GIST.

scientific article published in March 2007

Surgical technique, morbidity, and outcome of primary retroperitoneal sarcoma involving inferior vena cava

scientific article published on 27 July 2011

Survival of adults with cancers of bone or soft tissue in Europe-Report from the EUROCARE-5 study

Synovial sarcoma: a retrospective analysis of 271 patients of all ages treated at a single institution

scientific article

Systemic Therapy Options for Unresectable and Metastatic Chordomas ⬇️

scientific article published on August 1, 2011

Systemic therapy for selected skull base sarcomas: Chondrosarcoma, chordoma, giant cell tumour and solitary fibrous tumour/hemangiopericytoma

scientific article published on 13 January 2016

Systemic treatments in MDM2 positive intimal sarcoma: A multicentre experience with anthracycline, gemcitabine, and pazopanib within the World Sarcoma Network

scientific article published on 19 September 2019

Targeted therapies in rare sarcomas: IMT, ASPS, SFT, PEComa, and CCS.

scientific article published on October 2013

Ten-Year Progression-Free and Overall Survival in Patients With Unresectable or Metastatic GI Stromal Tumors: Long-Term Analysis of the European Organisation for Research and Treatment of Cancer, Italian Sarcoma Group, and Australasian Gastrointesti

scientific article published on 31 March 2017

Tenosynovial giant cell tumour/pigmented villonodular synovitis: outcome of 294 patients before the era of kinase inhibitors.

scientific article published on 24 November 2014

The GOLD ReGISTry: a Global, Prospective, Observational Registry Collecting Longitudinal Data on Patients with Advanced and Localised Gastrointestinal Stromal Tumours

scientific article

The HoxC4 homeodomain protein mediates activation of the immunoglobulin heavy chain 3' hs1,2 enhancer in human B cells. Relevance to class switch DNA recombination

scientific article

The consensus statement on the locoregional treatment of abdominal sarcomatosis.

scientific article published on September 2008

The current and future role of the medical oncologist in the professional care for cancer patients: a position paper by the European Society for Medical Oncology (ESMO).

scientific article published on 13 December 2013

The impact of chemotherapy on survival of patients with extremity and trunk wall soft tissue sarcoma: revisiting the results of the EORTC-STBSG 62931 randomised trial

scientific article published on 25 January 2019

The intriguing patterns of tumor response to trabectedin ⬇️

scientific article published on June 1, 2013

The natural history of epithelioid sarcoma. A retrospective multicentre case-series within the Italian Sarcoma Group

scientific article published on 08 April 2020

The off-label use of drugs in oncology: a position paper by the European Society for Medical Oncology (ESMO)

article

The prognostic impact of dedifferentiation in retroperitoneal liposarcoma: a series of surgically treated patients at a single institution

scientific article published in October 2008

The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation

scientific article

Time to Definitive Failure to the First Tyrosine Kinase Inhibitor in Localized GI Stromal Tumors Treated With Imatinib As an Adjuvant: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Intergroup Randomi

scientific article published on 16 November 2015

Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses

scientific article

Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors

scientific article

Trabectedin and RAdiotherapy in Soft Tissue Sarcoma (TRASTS): Results of a Phase I Study in Myxoid Liposarcoma from Spanish (GEIS), Italian (ISG), French (FSG) Sarcoma Groups

article

Trabectedin in advanced synovial sarcomas: a multicenter retrospective study from four European institutions and the Italian Rare Cancer Network

scientific article published on July 2015

Trabectedin in advanced uterine leiomyosarcomas: A retrospective case series analysis from two reference centers

scientific article published on 13 September 2011

Trabectedin in myxoid liposarcomas (MLS): a long-term analysis of a single-institution series.

scientific article

Trabectedin therapy for sarcomas.

scientific article published on July 2010

Translocation-related sarcomas.

scientific article published on August 2009

Treatment Outcomes and Sensitivity to Hormone Therapy of Aggressive Angiomyxoma: A Multicenter, International, Retrospective Study

scientific article published on 05 December 2018

Treatment challenges in and outside a network setting: Soft tissue sarcomas

scientific article

Tumor response assessment by modified Choi criteria in localized high-risk soft tissue sarcoma treated with chemotherapy

scientific article published on 17 May 2012

Tumor response to sunitinib malate observed in clear-cell sarcoma.

scientific article published on 21 January 2010

Uterine sarcomas: a multidisciplinary challenge.

scientific article published on September 2011

Validation and adaptation of a nomogram for predicting the survival of patients with extremity soft tissue sarcoma using a three-grade system

scientific article published on 01 January 2005

Variability in Patterns of Recurrence After Resection of Primary Retroperitoneal Sarcoma (RPS): A Report on 1007 Patients From the Multi-institutional Collaborative RPS Working Group.

scientific article published on 31 December 2015

Vascular resection en-bloc with tumor removal and graft reconstruction is safe and effective in soft tissue sarcoma (STS) of the extremities and retroperitoneum

scientific article published on 07 May 2016

Vatalanib for metastatic gastrointestinal stromal tumour (GIST) resistant to imatinib: final results of a phase II study.

scientific article

When does a new sarcoma exist?

scientific article published on 13 September 2020

c-Kit/PDGFRA gene status alterations possibly related to primary imatinib resistance in gastrointestinal stromal tumors

scientific article published in April 2007

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