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List of works by Alessandro Gronchi

2018 ESMO Sarcoma and GIST Symposium: 'take-home messages' in soft tissue sarcoma.

scientific article published on 28 June 2018

9p21 locus analysis in high-risk gastrointestinal stromal tumors characterized for c-kit and platelet-derived growth factor receptor alpha gene alterations.

scientific article

A Prospective Observational Study of Multivisceral Resection for Retroperitoneal Sarcoma: Clinical and Patient-Reported Outcomes 1 Year After Surgery

scientific article published on 11 November 2020

A call to action: why sarcoma surgery needs to be centralized

scientific article published on 14 October 2018

A new mutation in the KIT ATP pocket causes acquired resistance to imatinib in a gastrointestinal stromal tumor patient

scientific article

A nonrandom association of gastrointestinal stromal tumor (GIST) and desmoid tumor (deep fibromatosis): case series of 28 patients

scientific article

AKT1 and BRAF mutations in pediatric aggressive fibromatosis

scientific article published on 08 April 2016

ASO Author Reflections: A Breach in the Border-Retroperitoneal Sarcoma with an Intraperitoneal Component

scientific article published on 25 October 2019

ASO Author Reflections: Evolving Concepts for Radiation Therapy in Extremity and Trunk Soft Tissue Sarcoma

scientific article published on 12 November 2018

ASO Author Reflections: Moving the Needle in Extremity and Trunk Soft Tissue Sarcoma

scientific article published on 24 August 2020

ASO Author Reflections: Understanding the Impact of Primary Retroperitoneal Sarcoma Resection on Patient Well-being: One Step Forward in Learning How Caring for Patients is as Important as Curing Their Cancers

scientific article published on 28 November 2020

Abdominosacral resection for locally recurring rectal cancer

scientific article published on December 2016

Absence of progression, not extent of tumour shrinkage, defines prognosis in soft-tissue sarcoma - An analysis of the EORTC 62012 study of the EORTC STBSG.

scientific article published on 17 June 2016

Accreditation for centers of sarcoma surgery.

scientific article published on 8 August 2016

Activate and resist: L576P-KIT in GIST.

scientific article published in September 2009

Activity of anthracycline- and ifosfamide-based chemotherapy in a series of patients affected by advanced myxofibrosarcoma

scientific article published on 22 August 2017

Activity of axitinib in progressive advanced solitary fibrous tumour: Results from an exploratory, investigator-driven phase 2 clinical study

scientific article published on 05 December 2018

Activity of sunitinib in extraskeletal myxoid chondrosarcoma

scientific article published on 02 April 2014

Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment.

scientific article published on 5 September 2016

Adaptive immune contexture at the tumour site and downmodulation of circulating myeloid-derived suppressor cells in the response of solitary fibrous tumour patients to anti-angiogenic therapy

scientific article

Addition of anti-estrogen treatment in patients with malignant PEComa progressing to mTOR inhibitors

scientific article published on 30 June 2020

Adequate Local Control in High-Risk Soft Tissue Sarcoma of the Extremity Treated with Surgery Alone at a Reference Centre: Should Radiotherapy Still be a Standard?

scientific article published on 22 February 2018

Adjacent, Adherent, Invaded: A Spectrum of Biologic Aggressiveness Rather Than a Rationale for Selecting Organ Resection in Surgery of Primary Retroperitoneal Sarcomas.

scientific article

Adjuvant Therapy for High-Risk Soft Tissue Sarcoma in the Adult ⬇️

scientific article published on September 1, 2013

Adjuvant therapy of gastrointestinal stromal tumors (GIST).

scientific article published on September 2012

Adjuvant treatment of GIST with imatinib: solid ground or still quicksand? A comment on behalf of the EORTC Soft Tissue and Bone Sarcoma Group, the Italian Sarcoma Group, the NCRI Sarcoma Clinical Studies Group (UK), the Japanese Study Group on GIST

scientific article published on 13 March 2009

Adult-Type Soft Tissue Sarcomas in Pediatric-Age Patients: Experience at the Istituto Nazionale Tumori in Milan

scientific article published on 14 March 2005

Adult-type soft tissue sarcomas in paediatric age: A nomogram-based prognostic comparison with adult sarcoma

scientific article published on 30 October 2007

Advanced Extremity Soft Tissue Sarcoma: Prognostic Effect of Isolated Limb Perfusion in a Series of 88 Patients Treated at a Single Institution

scientific article published on 23 November 2006

Aggressive Surgery in Retroperitoneal Soft Tissue Sarcoma Carried Out at High-Volume Centers is Safe and is Associated With Improved Local Control

scientific article published on 01 June 2010

Aggressive Surgical Policies in a Retrospectively Reviewed Single-Institution Case Series of Retroperitoneal Soft Tissue Sarcoma Patients

scientific article published on 01 December 2008

Aggressive fibromatosis in children and adolescents: the Italian experience

scientific article published in January 2010

Alveolar soft part sarcoma: clinical presentation, treatment, and outcome in a series of 33 patients at a single institution.

scientific article

An Update on Non-extremity Soft Tissue Sarcomas.

scientific article published on 19 March 2017

Analysis of potential receptor tyrosine kinase targets in intimal and mural sarcomas

article

Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas

scientific article published on 17 February 2010

Angiosarcoma of the breast and vascular endothelial growth factor receptor.

scientific article

Anthracycline, Gemcitabine, and Pazopanib in Epithelioid Sarcoma: A Multi-institutional Case Series

scientific article published on 13 September 2018

Anthracycline-based chemotherapy in extraskeletal myxoid chondrosarcoma: a retrospective study

scientific article published on 18 December 2013

Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells.

scientific article

Are We Allowed to Limit Surgical Aggressiveness With Small Rectal Gastrointestinal Stromal Tumors?

scientific article

Atypical pleomorphic epithelioid angiomyolipoma localized to the pelvis: a case report and review of the literature.

scientific article published on March 2004

Axial skeletal osteosarcoma: a 25-year monoinstitutional experience in children and adolescents

scientific article published on 21 February 2014

Banked venous homograft replacement of the inferior vena cava for primary leiomyosarcoma

scientific article published on 13 November 2006

Baseline and Postoperative C-reactive Protein Levels Predict Long-Term Survival After Lung Metastasectomy

scientific article published on 03 January 2019

Best practices for the management of local-regional recurrent chordoma: a position paper by the Chordoma Global Consensus Group.

scientific article

Botulinum toxin type A affects the transcriptome of cell cultures derived from muscle biopsies of controls and spastic patients

scientific article published on 6 March 2018

CTNNB1 45F mutation is a molecular prognosticator of increased postoperative primary desmoid tumor recurrence: an independent, multicenter validation study.

scientific article published on 31 July 2013

Cancer registries and randomised clinical trials in rare tumours: At the two extremes of daily clinical practice

scientific article published on 05 July 2016

Carney triad: case report and molecular analysis of gastric tumor

scientific article

Chordoma

scientific article published on 01 July 2007

Chordoma of the mobile spine and sacrum: a retrospective analysis of a series of patients surgically treated at two referral centers

scientific article published on 22 October 2009

Chordoma: natural history and results in 28 patients treated at a single institution.

scientific article published in April 2003

Clinical, pathological and surgical characteristics of duodenal gastrointestinal stromal tumor and their influence on survival: a multi-center study.

scientific article published on 28 July 2012

Collaborations between SSO and the Connective Tissue Oncology Society (CTOS) series

scientific article published on 07 July 2015

Combination of PPARγ Agonist Pioglitazone and Trabectedin Induce Adipocyte Differentiation to Overcome Trabectedin Resistance in Myxoid Liposarcomas

scientific article published on 03 September 2019

Comparative Assessment of Antitumor Effects and Autophagy Induction as a Resistance Mechanism by Cytotoxics and EZH2 Inhibition in INI1-Negative Epithelioid Sarcoma Patient-Derived Xenograft

scientific article published on 19 July 2019

Completion surgery of residual disease after primary inadequate surgery of retroperitoneal sarcomas can salvage a selected subgroup of patients-A propensity score analysis

scientific article published on 16 December 2018

Consensus meeting for the management of gastrointestinal stromal tumors. Report of the GIST Consensus Conference of 20-21 March 2004, under the auspices of ESMO.

scientific article

Consistent Margin-Status Reporting in Soft Tissue Sarcoma Is Essential to Establish Risk-Adapted Strategies Integrating Biology and Histotype in Perioperative Treatments

scientific article published on 07 June 2018

Correction: Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin

scientific article published on 01 March 2020

Correlation between radiological assessment and histopathological diagnosis in retroperitoneal tumors: analysis of 291 consecutive patients at a tertiary reference sarcoma center.

scientific article published on 15 October 2014

Current concepts and future perspectives in retroperitoneal soft-tissue sarcoma management.

scientific article published on August 2009

Cyclooxygenase-2 and platelet-derived growth factor receptors as potential targets in treating aggressive fibromatosis

scientific article

Cytoreductive surgery (peritonectomy) and intraperitoneal hyperthermic chemotherapy: an innovative and effective approach to the treatment of pseudomyxoma peritonei

scientific article published in July 2003

Cytoreductive surgery in advanced GIST: timing is everything

scientific article published in October 2013

Dacarbazine in solitary fibrous tumor: a case series analysis and preclinical evidence vis-a-vis temozolomide and antiangiogenics

scientific article published on 25 July 2013

Denosumab treatment of inoperable or locally advanced giant cell tumor of bone - Multicenter analysis outside clinical trial

scientific article published on 31 March 2018

Dermatofibrosarcoma protuberans-derived fibrosarcoma: clinical history, biological profile and sensitivity to imatinib.

scientific article

Desmoid-Type Fibromatosis: Evolving Treatment Standards.

scientific article

Desmoid-type fibromatosis and pregnancy: a multi-institutional analysis of recurrence and obstetric risk.

scientific article

Desmoid-type fibromatosis: What works best?

scientific article published on 01 September 2009

Desmoid-type fibromatosis: a front-line conservative approach to select patients for surgical treatment.

scientific article

Development and external validation of two nomograms to predict overall survival and occurrence of distant metastases in adults after surgical resection of localised soft-tissue sarcomas of the extremities: a retrospective analysis

scientific article published on 5 April 2016

Development of transplantable human chordoma xenograft for preclinical assessment of novel therapeutic strategies

scientific article

Doxorubicin plus dacarbazine, doxorubicin plus ifosfamide, or doxorubicin alone as a first-line treatment for advanced leiomyosarcoma: A propensity score matching analysis from the European Organization for Research and Treatment of Cancer Soft Tiss

scientific article published on 04 March 2020

Doxorubicin-based adjuvant chemotherapy in soft tissue sarcoma: pooled analysis of two STBSG-EORTC phase III clinical trials.

scientific article published on 6 October 2014

Effect of Neoadjuvant Chemotherapy Plus Regional Hyperthermia on Long-term Outcomes Among Patients With Localized High-Risk Soft Tissue Sarcoma: The EORTC 62961-ESHO 95 Randomized Clinical Trial.

scientific article published on 15 February 2018

Efficacy and Biological Activity of Imatinib in Metastatic Dermatofibrosarcoma Protuberans (DFSP).

scientific article

Efficacy and economic value of adjuvant imatinib for gastrointestinal stromal tumors

scientific article

Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study

scientific article published on July 2007

Emerging therapies for adult soft tissue sarcoma.

scientific article

Epithelioid sarcoma in children and adolescents: a report from the Italian Soft Tissue Sarcoma Committee.

scientific article

Epithelioid sarcoma: prognostic factors and survival in a series of patients treated at a single institution

scientific article published on 2 October 2007

Establishment and characterisation of a new patient-derived model of myxoid liposarcoma with acquired resistance to trabectedin

scientific article published on 14 August 2019

European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Experience with Advanced/Metastatic Epithelioid Sarcoma Patients Treated in Prospective Trials: Clinical Profile and Response to Systemic Therapy ⬇️

scientific article published on 15 March 2018

Evaluation of response after neoadjuvant treatment in soft tissue sarcomas; the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) recommendations for pathological examination and reporting.

scientific article published on 14 December 2015

Evaluation of response after pre-operative radiotherapy in soft tissue sarcomas; the European Organisation for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) and Imaging Group recommendations for radiological exami

scientific article published on 20 January 2016

Evidence of neural differentiation in a case of post-therapy primitive neuroectodermal tumor/Ewing sarcoma of bone

scientific article published in August 2003

Expression of ligand-activated KIT and platelet-derived growth factor receptor beta tyrosine kinase receptors in synovial sarcoma

scientific article published on February 2004

External Beam Radiation Therapy for Resectable Soft Tissue Sarcoma: A Systematic Review and Meta-Analysis.

scientific article published on 11 September 2017

External validation of a multi-institutional retroperitoneal sarcoma nomogram

scientific article

Extra-abdominal desmoid fibromatosis: A review of management, current guidance and unanswered questions

scientific article

Extraskeletal myxoid chondrosarcoma: tumor response to sunitinib

scientific article

Extraskeletal osteosarcoma: A European Musculoskeletal Oncology Society study on 266 patients.

scientific article

Extremity Soft Tissue Sarcoma in a Series of Patients Treated at a Single Institution

scientific article published on 01 March 2010

Extremity Soft Tissue Sarcoma: Adding to the Prognostic Meaning of Local Failure

scientific article published on 28 January 2007

Feasibility of Preoperative Chemotherapy With or Without Radiation Therapy in Localized Soft Tissue Sarcomas of Limbs and Superficial Trunk in the Italian Sarcoma Group/Grupo Español de Investigación en Sarcomas Randomized Clinical Trial: Three Vers

scientific article

Feasibility of peritonectomy associated with intraperitoneal hyperthermic perfusion in patients with Pseudomyxoma peritonei

scientific article published on 01 September 2002

Fluorescence in situ hybridization analysis and immunophenotyping of c-Kit/PDGFRA and Bcl-2 expression in gastrointestinal stromal tumors.

scientific article

Frontline extended surgery is associated with improved survival in retroperitoneal low- to intermediate-grade soft tissue sarcomas.

scientific article published on 16 July 2011

Functional analyses and molecular modeling of two c-Kit mutations responsible for imatinib secondary resistance in GIST patients

article

Gastrointestinal stromal tumor of the rectum: results of surgical and multimodality therapy in the era of imatinib

scientific article published on 11 September 2012

Gastrointestinal stromal tumors I: pathology, pathobiology, primary therapy, and surgical issues

scientific article published on August 2009

Gastrointestinal stromal tumors: evolving role of the multidisciplinary team approach in management.

scientific article published on 14 May 2012

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2018

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published in October 2018

Genetic susceptibility to bone and soft tissue sarcomas: a field synopsis and meta-analysis.

scientific article published on 6 April 2018

Genome-Wide Analysis Identifies MEN1 and MAX Mutations and a Neuroendocrine-Like Molecular Heterogeneity in Quadruple WT GIST.

scientific article published on 27 January 2017

Guidelines for time-to-event end point definitions in sarcomas and gastrointestinal stromal tumors (GIST) trials: results of the DATECAN initiative (Definition for the Assessment of Time-to-event Endpoints in CANcer trials)†.

scientific article

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma

scientific article published on 6 April 2017

Head and neck soft tissue sarcomas: prognostic factors and outcome in a series of patients treated at a single institution

scientific article

Hemangiopericytoma in pediatric ages: a report from the Italian and German Soft Tissue Sarcoma Cooperative Group

scientific article published on 01 November 2001

High CD133 expression levels in gastrointestinal stromal tumors

scientific article published on April 2011

High-Dose Ifosfamide Chemotherapy in a Series of Patients Affected by Myxoid Liposarcoma.

scientific article published on 30 August 2017

High-dose continuous-infusion ifosfamide in advanced well-differentiated/dedifferentiated liposarcoma

scientific article

High-grade sarcomatous overgrowth in solitary fibrous tumors: a clinicopathologic study of 10 cases

scientific article

High-grade soft-tissue sarcomas: tumor response assessment--pilot study to assess the correlation between radiologic and pathologic response by using RECIST and Choi criteria

scientific article published on 4 March 2009

High-risk soft tissue sarcomas treated with perioperative chemotherapy: Improving prognostic classification in a randomised clinical trial

scientific article published on 21 February 2018

Highlights in soft tissue sarcomas and gastrointestinal stromal tumours (GIST) trials reported at ASCO 2017 Annual Meeting.

scientific article published on 22 August 2017

Histology-specific nomogram for primary retroperitoneal soft tissue sarcoma

scientific article published in May 2010

Historical perspectives and future directions in the surgical management of retroperitoneal sarcoma.

scientific article published on 11 November 2017

Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial

scientific article

Hormonal manipulation with toremifene in sporadic desmoid-type fibromatosis.

scientific article published on 18 November 2015

Human equilibrative nucleoside transporter 1 gene expression is associated with gemcitabine efficacy in advanced leiomyosarcoma and angiosarcoma

scientific article published on 22 June 2017

Hyperthermia as an adjunctive treatment for soft-tissue sarcoma.

scientific article published on February 2009

Hyperthermic intraperitoneal intraoperative chemotherapy after cytoreductive surgery for the treatment of abdominal sarcomatosis

scientific article published on 01 May 2004

ILP and RT: the study that will never be

scientific article published on 01 February 2011

Identification of a gene expression driven progression pathway in myxoid liposarcoma

scientific article

Identification of an Actionable Mutation of KIT in a Case of Extraskeletal Myxoid Chondrosarcoma

scientific article published on 23 June 2018

Imatinib and everolimus in patients with progressing advanced chordoma: A phase 2 clinical study

scientific article published on 14 September 2018

Imatinib in advanced chordoma: A retrospective case series analysis

scientific article

Imatinib mesylate in chordoma

scientific article

Imatinib response in two GIST patients carrying two hitherto functionally uncharacterized PDGFRA mutations: an imaging, biochemical and molecular modeling study

scientific article published in February 2011

Impact of chemotherapy in uterine sarcoma (UtS): review of 13 clinical trials from the EORTC Soft Tissue and Bone Sarcoma Group (STBSG) involving advanced/metastatic UtS compared to other soft tissue sarcoma (STS) patients treated with first line ch

scientific article published on 18 May 2016

Impact of perioperative chemotherapy and radiotherapy in patients with primary extremity soft tissue sarcoma: retrospective analysis across major histological subtypes and major reference centres

scientific article published on 29 October 2018

Improved Biopsy Accuracy in Retroperitoneal Dedifferentiated Liposarcoma

scientific article published on 04 May 2020

In vitro and in silico studies of MDM2/MDMX isoforms predict Nutlin-3A sensitivity in well/de-differentiated liposarcomas.

scientific article published on 9 September 2013

Indications for surgery in advanced/metastatic GIST.

scientific article published on 16 June 2016

Individualizing the use/non-use of radiation therapy (RT) in soft tissue sarcoma (STS): When abstention is better than care

scientific article published on 03 November 2014

Intraperitoneal Invasion of Retroperitoneal Sarcomas: A Risk Factor for Dismal Prognosis

scientific article published on 16 July 2019

Is autophagy rather than apoptosis the regression driver in imatinib-treated gastrointestinal stromal tumors?

scientific article published on December 2008

Isolated limb perfusion using tumour necrosis factor α and melphalan in patients with advanced aggressive fibromatosis.

scientific article

KIT, PDGFRA, and BRAF mutational spectrum impacts on the natural history of imatinib-naive localized GIST: a population-based study

scientific article published on July 2015

Lack of SYT-SSX fusion transcripts in malignant peripheral nerve sheath tumors on RT-PCR analysis of 34 archival cases

scientific article published on May 2002

Leiomyosarcoma and sarcoma with myogenic differentiation

scientific article published on 19 April 2012

Localised thoracic sarcomas: outcome improvement over time at a single institution

scientific article published on 14 May 2013

Long-Term Results of Thoraco-Pleuro-Pneumonectomy (TPP) for Recurrent Thoracic Sarcomas

scientific article published on 20 November 2017

Long-term Efficacy of Methotrexate Plus Vinblastine/Vinorelbine in a Large Series of Patients Affected by Desmoid-Type Fibromatosis.

scientific article published on March 2017

Long-term Follow-up and Post-relapse Outcome of Patients with Localized Retroperitoneal Sarcoma Treated in the Italian Sarcoma Group-Soft Tissue Sarcoma (ISG-STS) Protocol 0303.

scientific article published on 17 October 2017

Long-term follow-up of patients with GIST undergoing metastasectomy in the era of imatinib -- analysis of prognostic factors (EORTC-STBSG collaborative study).

scientific article published on 15 January 2014

Long-term morbidity after multivisceral resection for retroperitoneal sarcoma

scientific article published on 3 June 2015

Low-dose chemotherapy with methotrexate and vinblastine for patients with advanced aggressive fibromatosis.

scientific article

MRP1 overexpression determines poor prognosis in prospectively treated patients with localized high-risk soft tissue sarcoma of limbs and trunk wall: an ISG/GEIS study.

scientific article

Malignant peripheral nerve sheath tumors

scientific article published on 01 September 2006

Management of meningeal solitary fibrous tumors/hemangiopericytoma; surgery alone or surgery plus postoperative radiotherapy?

scientific article published on 29 September 2020

Management of sporadic desmoid-type fibromatosis: a European consensus approach based on patients' and professionals' expertise - a sarcoma patients EuroNet and European Organisation for Research and Treatment of Cancer/Soft Tissue and Bone Sarcoma

scientific article published on 27 November 2014

Mesenchymal chondrosarcoma: prognostic factors and outcome in 113 patients. A European Musculoskeletal Oncology Society study

scientific article published on 16 December 2014

Meta-analysis of the influence of surgical margin and adjuvant radiotherapy on local recurrence after resection of sporadic desmoid-type fibromatosis.

scientific article

Minimally Invasive Surgery for Retroperitoneal Sarcoma: Just Because We Can Does Not Mean We Should

scientific article published on 14 June 2018

Mode of action of trabectedin in myxoid liposarcomas.

scientific article published on 11 November 2013

Molecular and biochemical analyses of platelet-derived growth factor receptor (PDGFR) B, PDGFRA, and KIT receptors in chordomas

scientific article published in December 2006

Morbidity of left pancreatectomy when associated with multivisceral resection for abdominal mesenchymal neoplasms

scientific article

Morcellator's Port-site Metastasis of a Uterine Smooth Muscle Tumor of Uncertain Malignant Potential After Minimally Invasive Myomectomy

scientific article published on 2 February 2016

Myogenic Differentiation and Histologic Grading Are Major Prognostic Determinants in Retroperitoneal Liposarcoma

scientific article published on 01 March 2015

Myxofibrosarcoma: Prognostic Factors and Survival in a Series of Patients Treated at a Single Institution

scientific article published on 28 September 2010

Myxoid/round cell and pleomorphic liposarcomas: prognostic factors and survival in a series of patients treated at a single institution

scientific article

NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST)--update of the NCCN clinical practice guidelines.

scientific article published on July 2007

NR4A3 fusion proteins trigger an axon guidance switch that marks the difference between EWSR1 and TAF15 translocated extraskeletal myxoid chondrosarcomas

scientific article published on 14 May 2019

Natural history of imatinib-naive GISTs: a retrospective analysis of 929 cases with long-term follow-up and development of a survival nomogram based on mitotic index and size as continuous variables

scientific article

Neoadjuvant and adjuvant strategies in retroperitoneal sarcoma

scientific article published on 09 February 2018

Neoadjuvant chemotherapy in soft tissue sarcomas: latest evidence and clinical implications.

scientific article

Neoadjuvant imatinib in locally advanced gastrointestinal stromal tumors (GIST): the EORTC STBSG experience

scientific article published on 13 June 2013

Neoadjuvant treatment: a novel standard?

scientific article

Neurofibromin C terminus-specific antibody (clone NFC) is a valuable tool for the identification of NF1-inactivated GISTs.

scientific article

Novel intra-genic large deletions of CTNNB1 gene identified in WT desmoid-type fibromatosis

article

Novel models of myxoid liposarcoma xenografts mimicking the biological and pharmacologic features of human tumors.

scientific article published on 20 August 2010

Oncogenic and ligand-dependent activation of KIT/PDGFRA in surgical samples of imatinib-treated gastrointestinal stromal tumours (GISTs).

scientific article published in January 2009

Optimal approach to sporadic desmoid tumors: from radical surgery to observation. Time for a consensus?

scientific article published on 01 December 2012

Outcome prediction in primary resected retroperitoneal soft tissue sarcoma: histology-specific overall survival and disease-free survival nomograms built on major sarcoma center data sets

scientific article

Outcomes of Elderly Patients with Advanced Soft Tissue Sarcoma Treated with First-Line Chemotherapy: A Pooled Analysis of 12 EORTC Soft Tissue and Bone Sarcoma Group Trials.

scientific article published on 12 April 2018

PDGFRA, PDGFRB, EGFR, and downstream signaling activation in malignant peripheral nerve sheath tumor

scientific article published on December 2009

Pancreaticoduodenectomy in the surgical management of primary retroperitoneal sarcoma.

scientific article published on 5 February 2018

Patient-derived solitary fibrous tumour xenografts predict high sensitivity to doxorubicin/dacarbazine combination confirmed in the clinic and highlight the potential effectiveness of trabectedin or eribulin against this tumour.

scientific article published on 8 March 2017

Pazopanib in advanced vascular sarcomas: an EORTC Soft Tissue and Bone Sarcoma Group (STBSG) retrospective analysis

scientific article published on 14 November 2016

Perioperative Management of Extremity Soft Tissue Sarcomas.

scientific article published on 8 December 2017

Peritoneal Sarcomatosis: Is There a Subset of Patients Who May Benefit from Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy?

scientific article published on 29 June 2010

Personalizing surgical margins in retroperitoneal sarcomas

scientific article published on 23 March 2015

Personalizing surgical margins in retroperitoneal sarcomas: an update

scientific article published on 08 June 2019

Personalizing the Approach to Retroperitoneal Soft Tissue Sarcoma: Histology-specific Patterns of Failure and Postrelapse Outcome after Primary Extended Resection

scientific article published on 10 October 2014

Pexidartinib for the treatment of adult symptomatic patients with tenosynovial giant cell tumors

scientific article published on 01 June 2020

Pharmacotherapy for liposarcoma: current state of the art and emerging systemic treatments

scientific article published on 28 May 2019

Phase II clinical trial of neoadjuvant trabectedin in patients with advanced localized myxoid liposarcoma

scientific article published on 03 June 2011

Phase II study of imatinib in advanced chordoma

scientific article

Phase II study on lapatinib in advanced EGFR-positive chordoma

scientific article published on 4 April 2013

Post-imatinib surgery in advanced/metastatic GIST: is it worthwhile in all patients?

scientific article published on 23 July 2009

Post-relapse outcomes after primary extended resection of retroperitoneal sarcoma: A report from the Trans-Atlantic RPS Working Group.

scientific article published on 02 February 2017

Postoperative Morbidity After Radical Resection of Primary Retroperitoneal Sarcoma: A Report From the Transatlantic RPS Working Group.

scientific article published on 07 April 2017

Preclinical and clinical evidence of activity of pazopanib in solitary fibrous tumour

scientific article published on 27 September 2014

Predictive and prognostic factors associated with soft tissue sarcoma response to chemotherapy: a subgroup analysis of the European Organisation for Research and Treatment of Cancer 62012 study

scientific article

Predictors for doxorubicin-induced hematological toxicity and its association with outcome in advanced soft tissue sarcoma patients; a retrospective analysis of the EORTC-soft tissue and bone sarcoma group database

scientific article published on 09 March 2018

Preoperative chemo-radiation therapy for localised retroperitoneal sarcoma: a phase I-II study from the Italian Sarcoma Group.

scientific article

Preoperative imatinib mesylate for unresectable or locally advanced primary gastrointestinal stromal tumors (GIST).

scientific article

Preoperative radiation therapy for patients with T2-T3 carcinoma of the middle-to-lower rectum

scientific article published on 01 August 1999

Primary extremity soft tissue sarcomas: outcome improvement over time at a single institution

scientific article published on 17 January 2011

Prognostic Effect of Re-Excision in Adult Soft Tissue Sarcoma of the Extremity

scientific article published on 01 January 2006

Prognostic Factors and Outcome of Spermatic Cord Sarcoma

scientific article published on 07 May 2014

Prognostic determinants in epithelioid sarcoma.

scientific article published in January 2011

Prognostic factors for soft tissue sarcoma patients with lung metastases only who are receiving first-line chemotherapy: An exploratory, retrospective analysis of the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sa

scientific article published on 31 January 2018

Prognostic relevance of ALT-associated markers in liposarcoma: a comparative analysis.

scientific article

Prognostic relevance of distant metastases versus locally advanced disease in soft tissue sarcomas: An EORTC-STBSG database study

scientific article published on 22 March 2018

Prospective assessment of the predictive value of the BRCA1 gene status in sarcoma patients treated with trabectedin: an updated analysis of the EORTC 62091 trial.

scientific article

Proteomic detection of a large amount of SCGFα in the stroma of GISTs after imatinib therapy

scientific article

Quadruple-Negative GIST Is a Sentinel for Unrecognized Neurofibromatosis Type 1 Syndrome

scientific article published on 7 July 2016

Quality of Surgery and Outcome in Localized Gastrointestinal Stromal Tumors Treated Within an International Intergroup Randomized Clinical Trial of Adjuvant Imatinib

scientific article published on 01 April 2020

Quality of local treatment or biology of the tumor: which are the trump cards for loco-regional control of retroperitoneal sarcoma?

scientific article published in July 2013

Quality of surgery and neoadjuvant combined therapy in the ISG-GEIS trial on soft tissue sarcomas of limbs and trunk wall.

scientific article published on 30 October 2012

Quality of surgery and outcome in extra-abdominal aggressive fibromatosis: a series of patients surgically treated at a single institution.

scientific article

Radiation-Induced Sarcoma of the Head and Neck: A Review of the Literature

scientific article published on 17 October 2018

Radiomic analysis of soft tissues sarcomas can distinguish intermediate from high-grade lesions.

scientific article

Receptor tyrosine kinase pathway analysis sheds light on similarities between clear-cell sarcoma and metastatic melanoma.

scientific article

Renal angiomyolipomas: At least two diseases. A series of patients treated at two European institutions.

scientific article published on 5 December 2016

Reply to Deleterious effect of ifosfamide in leiomyosarcoma: Convergence of weak signals

scientific article published on 07 August 2020

Resectable extra-pleural and extra-meningeal solitary fibrous tumours: A multi-centre prognostic study.

scientific article

Resection of uninvolved adjacent organs can be part of surgery for retroperitoneal soft tissue sarcoma

scientific article published on 09 March 2009

Response to chemotherapy of solitary fibrous tumour: A retrospective study

scientific article published on 06 April 2013

Response to imatinib plus sirolimus in advanced chordoma.

scientific article published in July 2009

Response to sunitinib malate in advanced alveolar soft part sarcoma

scientific article

Retroperitoneal Liposarcoma: An Aggressive Strategy to Maximize Disease Control.

scientific article published in June 2017

Retroperitoneal sarcomas: Big tumors that involve more than just "Getting it Out".

scientific article published on 11 November 2017

Retroperitoneal soft tissue sarcomas: patterns of recurrence in 167 patients treated at a single institution.

scientific article published in June 2004

Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution

scientific article

Risk stratification models and mutational analysis: keys to optimising adjuvant therapy in patients with gastrointestinal stromal tumour.

scientific article published on December 2012

Role of Chemotherapy, VEGFR Inhibitors, and mTOR Inhibitors in Advanced Perivascular Epithelioid Cell Tumors (PEComas)

scientific article published on 19 June 2019

SYT-SSX fusion genes and prognosis in synovial sarcoma.

scientific article published on November 2001

Sacral Chordoma: Long-term Outcome of a Large Series of Patients Surgically Treated at Two Reference Centers.

scientific article

Sarcoma nomograms: a light over the darkness.

scientific article published on 16 March 2017

Second Primary Malignancies in Patients with Well-differentiated/Dedifferentiated Liposarcoma

scientific article published on 01 June 2018

Short, Full-Dose Adjuvant Chemotherapy in High-Risk Adult Soft Tissue Sarcomas: A Randomized Clinical Trial From the Italian Sarcoma Group and the Spanish Sarcoma Group

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Short, full-dose adjuvant chemotherapy (CT) in high-risk adult soft tissue sarcomas (STS): long-term follow-up of a randomized clinical trial from the Italian Sarcoma Group and the Spanish Sarcoma Group

scientific article published on 11 October 2016

Sirolimus in Advanced Epithelioid Hemangioendothelioma: A Retrospective Case-Series Analysis from the Italian Rare Cancer Network Database.

scientific article published on 22 June 2016

Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2018

Soft tissue sarcoma nomograms and their incorporation into practice.

scientific article

Soft tissue sarcomas of childhood and adolescence: the prognostic role of tumor size in relation to patient body size

scientific article published on 8 December 2008

Soft-tissue sarcomas of the extremities in patients of pediatric age.

scientific article published on September 2007

Solitary fibrous tumor of all sites: outcome of late recurrences in 14 patients.

scientific article published on 3 April 2013

Solitary fibrous tumors: loss of chimeric protein expression and genomic instability mark dedifferentiation

scientific article

Spontaneous regression of primary abdominal wall desmoid tumors: more common than previously thought.

scientific article

Sporadic desmoid-type fibromatosis: a stepwise approach to a non-metastasising neoplasm--a position paper from the Italian and the French Sarcoma Group

scientific article

Sporadic extra abdominal wall desmoid-type fibromatosis: surgical resection can be safely limited to a minority of patients.

scientific article

Staging, nomograms and other predictive tools in retroperitoneal soft tissue sarcoma

scientific article published on 01 August 2018

Status of Surgical Margins and Prognosis in Adult Soft Tissue Sarcomas of the Extremities: A Series of Patients Treated at a Single Institution

scientific article published on 01 January 2005

Sunitinib malate and figitumumab in solitary fibrous tumor: patterns and molecular bases of tumor response

scientific article

Sunitinib malate in solitary fibrous tumor (SFT) ⬇️

scientific article published on June 17, 2012

Surgery for recurrence in retroperitoneal leiomyosarcoma: Is it all about selection?

scientific article

Surgery in retroperitoneal soft tissue sarcoma: a call for a consensus between Europe and North America

scientific article published on 01 August 2011

Surgery of residual disease following molecular-targeted therapy with imatinib mesylate in advanced/metastatic GIST.

scientific article published in March 2007

Surgical management of localized soft tissue tumors.

scientific article published on 17 April 2014

Surgical management of retroperitoneal sarcoma and opportunities for global collaboration

scientific article published on 01 August 2018

Surgical resection as an adjuvant to tyrosine kinase inhibitors in metastatic GIST: Association or causation?/Are we any closer to an answer?

scientific article published on 18 June 2018

Surgical treatment of locally recurrent rectal carcinoma

scientific article published on 01 December 1997

Surrogate endpoints in advanced sarcoma trials: a meta-analysis

scientific article published on 02 October 2018

Synovial sarcoma: a retrospective analysis of 271 patients of all ages treated at a single institution

scientific article

Synovial sarcomas of the upper aero-digestive tract: is there a role for conservative surgery?

scientific article published on 11 January 2018

Systemic treatment in advanced soft tissue sarcoma: what is standard, what is new.

scientific article

Systemic treatments in MDM2 positive intimal sarcoma: A multicentre experience with anthracycline, gemcitabine, and pazopanib within the World Sarcoma Network

scientific article published on 19 September 2019

Tailored Beta-catenin mutational approach in extra-abdominal sporadic desmoid tumor patients without therapeutic intervention

scientific article

Technical considerations in surgery for retroperitoneal sarcomas: position paper from E-Surge, a master class in sarcoma surgery, and EORTC-STBSG.

scientific article published on 03 April 2012

Telomere Maintenance Mechanisms in Liposarcomas: Association with Histologic Subtypes and Disease Progression

scientific article published on 01 September 2006

Telomere as a Therapeutic Target in Dedifferentiated Liposarcoma

scientific article published on 25 May 2022

Telomere maintenance mechanisms in malignant peripheral nerve sheath tumors: expression and prognostic relevance

scientific article

Ten-Year Progression-Free and Overall Survival in Patients With Unresectable or Metastatic GI Stromal Tumors: Long-Term Analysis of the European Organisation for Research and Treatment of Cancer, Italian Sarcoma Group, and Australasian Gastrointesti

scientific article published on 31 March 2017

Tenosynovial giant cell tumour/pigmented villonodular synovitis: outcome of 294 patients before the era of kinase inhibitors.

scientific article published on 24 November 2014

The Diagnosis and Management of Retroperitoneal Sarcoma

scientific article published on 01 September 2018

The Italian Society of Surgical Oncology (SICO) survey on the minimum requirements of rare cancers referral centers

scientific article published on 16 June 2016

The Landmark Series: Multimodality Treatment of Extremity Sarcoma

scientific article published on 27 July 2020

The Trans-Atlantic Retroperitoneal Sarcoma Working Group (TARPSWG): "Red wine or white"?

scientific article

The Value of Neoadjuvant Chemotherapy in Localized High-Risk Soft-Tissue Sarcoma of the Extremities and Trunk

scientific article published on 01 September 2018

The combination of surgery and imatinib in GIST: a reality for localized tumors at high risk, an open issue for metastatic ones.

scientific article

The evolving role of patient advocates in rare cancers: opportunities and challenges

scientific article published on 27 September 2018

The prognostic impact of dedifferentiation in retroperitoneal liposarcoma: a series of surgically treated patients at a single institution

scientific article published in October 2008

The role of high-dose imatinib in the management of patients with gastrointestinal stromal tumor

scientific article published on April 2010

The role of hyperthermic intraperitoneal chemotherapy (HIPEC) and isolated perfusion (ILP) interventions in sarcoma.

scientific article

The safety and efficacy of trabectedin for the treatment of liposarcoma or leiomyosarcoma.

scientific article published on 4 April 2016

Therapeutic consequences from molecular biology for gastrointestinal stromal tumor patients affected by neurofibromatosis type 1.

scientific article published in July 2008

Thoracopleuropneumonectomy with Riblike Reconstruction for Recurrent Thoracic Sarcomas

Time to Definitive Failure to the First Tyrosine Kinase Inhibitor in Localized GI Stromal Tumors Treated With Imatinib As an Adjuvant: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Intergroup Randomi

scientific article published on 16 November 2015

Towards the standard use of (neo)adjuvant chemotherapy in selected localised soft tissue sarcoma at high risk of relapse: are we finally getting there?

scientific article published on 13 July 2018

Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors

scientific article

Trabectedin and RAdiotherapy in Soft Tissue Sarcoma (TRASTS): Results of a Phase I Study in Myxoid Liposarcoma from Spanish (GEIS), Italian (ISG), French (FSG) Sarcoma Groups

article

Trabectedin in myxoid liposarcomas (MLS): a long-term analysis of a single-institution series.

scientific article

Treatment challenges in and outside a network setting: Soft tissue sarcomas

scientific article

Treatment of localized sarcomas.

scientific article published on October 2013

Treatment of soft tissue sarcoma: a focus on earlier stages.

scientific article

Tumor response assessment by modified Choi criteria in localized high-risk soft tissue sarcoma treated with chemotherapy

scientific article published on 17 May 2012

Tumor response to sunitinib malate observed in clear-cell sarcoma.

scientific article published on 21 January 2010

Uterine sarcoma treated by cytoreductive surgery and intraperitoneal hyperthermic perfusion: a feasiblity study

scientific article published on 01 November 2004

Validation and adaptation of a nomogram for predicting the survival of patients with extremity soft tissue sarcoma using a three-grade system

scientific article published on 01 January 2005

Variability in Patterns of Recurrence After Resection of Primary Retroperitoneal Sarcoma (RPS): A Report on 1007 Patients From the Multi-institutional Collaborative RPS Working Group.

scientific article published on 31 December 2015

Vascular resection en-bloc with tumor removal and graft reconstruction is safe and effective in soft tissue sarcoma (STS) of the extremities and retroperitoneum

scientific article published on 07 May 2016

Working to improve the management of sarcoma patients across Europe: a policy checklist

scientific article published on 16 April 2018

c-Kit/PDGFRA gene status alterations possibly related to primary imatinib resistance in gastrointestinal stromal tumors

scientific article published in April 2007

p15INK4b, p14ARF, and p16INK4a inactivation in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors

scientific article published on 01 September 2003

β-Catenin in desmoid-type fibromatosis: deep insights into the role of T41A and S45F mutations on protein structure and gene expression.

scientific article published on 19 June 2017

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