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List of works by Silvia Stacchiotti

(Neo)adjuvant treatment in localised soft tissue sarcoma: The unsolved affair

scientific article published on 17 November 2016

A phase 2 trial of imatinib mesylate in patients with recurrent nonresectable chondrosarcomas expressing platelet-derived growth factor receptor-α or -β: An Italian Sarcoma Group study.

scientific article

Activity and safety of crizotinib in patients with advanced clear-cell sarcoma with MET alterations: European Organization for Research and Treatment of Cancer phase II trial 90101 'CREATE'.

scientific article published on 18 September 2017

Activity and safety of crizotinib in patients with alveolar soft part sarcoma with rearrangement of TFE3. European Organization for Research and Treatment of Cancer (EORTC) phase 2 trial 90101 "CREATE".

scientific article published on 5 December 2017

Activity of Pazopanib and Trabectedin in Advanced Alveolar Soft Part Sarcoma

scientific article

Activity of axitinib in progressive advanced solitary fibrous tumour: Results from an exploratory, investigator-driven phase 2 clinical study

scientific article published on 05 December 2018

Activity of sirolimus in patients with progressive epithelioid hemangioendothelioma: A case-series analysis within the Italian rare cancer network

scientific article published on 27 October 2020

Activity of sunitinib in extraskeletal myxoid chondrosarcoma

scientific article published on 02 April 2014

Adaptive Immunity in Fibrosarcomatous Dermatofibrosarcoma Protuberans and Response to Imatinib Treatment.

scientific article published on 5 September 2016

Adaptive immune contexture at the tumour site and downmodulation of circulating myeloid-derived suppressor cells in the response of solitary fibrous tumour patients to anti-angiogenic therapy

scientific article

Afatinib is a new therapeutic approach in chordoma with a unique ability to target EGFR and Brachyury

scientific article published on 13 December 2017

Aggressive Surgical Policies in a Retrospectively Reviewed Single-Institution Case Series of Retroperitoneal Soft Tissue Sarcoma Patients

scientific article published on 01 December 2008

Alveolar soft part sarcoma: clinical presentation, treatment, and outcome in a series of 33 patients at a single institution.

scientific article

Analysis of potential receptor tyrosine kinase targets in intimal and mural sarcomas

article

Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas

scientific article published on 17 February 2010

Anthracycline, Gemcitabine, and Pazopanib in Epithelioid Sarcoma: A Multi-institutional Case Series

scientific article published on 13 September 2018

Anthracycline-based chemotherapy in extraskeletal myxoid chondrosarcoma: a retrospective study

scientific article published on 18 December 2013

Best practices for the management of local-regional recurrent chordoma: a position paper by the Chordoma Global Consensus Group.

scientific article

Building a global consensus approach to chordoma: a position paper from the medical and patient community

scientific article published in February 2015

Chordoma

scientific article published on 01 July 2007

Chordoma of the mobile spine and sacrum: a retrospective analysis of a series of patients surgically treated at two referral centers

scientific article published on 22 October 2009

Chordoma: update on disease, epidemiology, biology and medical therapies

scientific article published on 01 March 2019

Completion surgery of residual disease after primary inadequate surgery of retroperitoneal sarcomas can salvage a selected subgroup of patients-A propensity score analysis

scientific article published on 16 December 2018

Complex Immune Contextures Characterise Malignant Peritoneal Mesothelioma: Loss of Adaptive Immunological Signature in the More Aggressive Histological Types

scientific article published on 29 October 2018

Correlation between radiological assessment and histopathological diagnosis in retroperitoneal tumors: analysis of 291 consecutive patients at a tertiary reference sarcoma center.

scientific article published on 15 October 2014

Current status and unanswered questions on the use of Denosumab in giant cell tumor of bone

scientific article

Denosumab treatment of inoperable or locally advanced giant cell tumor of bone - Multicenter analysis outside clinical trial

scientific article published on 31 March 2018

Dermatofibrosarcoma protuberans-derived fibrosarcoma: clinical history, biological profile and sensitivity to imatinib.

scientific article

Development and external validation of two nomograms to predict overall survival and occurrence of distant metastases in adults after surgical resection of localised soft-tissue sarcomas of the extremities: a retrospective analysis

scientific article published on 5 April 2016

Development of transplantable human chordoma xenograft for preclinical assessment of novel therapeutic strategies

scientific article published on 16 December 2013

Doxorubicin plus dacarbazine, doxorubicin plus ifosfamide, or doxorubicin alone as a first-line treatment for advanced leiomyosarcoma: A propensity score matching analysis from the European Organization for Research and Treatment of Cancer Soft Tiss

scientific article published on 04 March 2020

Efficacy and Biological Activity of Imatinib in Metastatic Dermatofibrosarcoma Protuberans (DFSP).

scientific article

Efficacy of imatinib mesylate for the treatment of locally advanced and/or metastatic tenosynovial giant cell tumor/pigmented villonodular synovitis.

scientific article

Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study

scientific article published on July 2007

Emerging therapies for adult soft tissue sarcoma.

scientific article

Epithelioid angiosarcoma of the thyroid gland without distant metastases at diagnosis: report of six cases with a long follow-up.

scientific article

Establishment and genomic characterization of the new chordoma cell line Chor-IN-1.

scientific article

Evaluation of response after neoadjuvant treatment in soft tissue sarcomas; the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) recommendations for pathological examination and reporting.

scientific article published on 14 December 2015

Evidence for PDGFRA, PDGFRB and KIT deregulation in an NSCLC patient.

scientific article published in January 2007

Extrameningeal solitary fibrous tumors-surgery alone or surgery plus perioperative radiotherapy: A retrospective study from the global solitary fibrous tumor initiative in collaboration with the sarcoma patients EuroNet

scientific article published on 21 April 2020

Extraskeletal myxoid chondrosarcoma: tumor response to sunitinib

scientific article

Extremity Soft Tissue Sarcoma in a Series of Patients Treated at a Single Institution

scientific article published on 01 March 2010

Frontline extended surgery is associated with improved survival in retroperitoneal low- to intermediate-grade soft tissue sarcomas.

scientific article published on 16 July 2011

Gastrointestinal stromal tumours: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2018

Gemcitabine in advanced angiosarcoma: a retrospective case series analysis from the Italian Rare Cancer Network

article

Genome-Wide Analysis Identifies MEN1 and MAX Mutations and a Neuroendocrine-Like Molecular Heterogeneity in Quadruple WT GIST.

scientific article published on 27 January 2017

Germline mutations of TP53 and BRCA2 genes in breast cancer/sarcoma families.

scientific article published on 16 January 2007

HSPA8 as a novel fusion partner of NR4A3 in extraskeletal myxoid chondrosarcoma

scientific article published on 6 April 2017

High-Dose Ifosfamide Chemotherapy in a Series of Patients Affected by Myxoid Liposarcoma.

scientific article published on 30 August 2017

High-grade sarcomatous overgrowth in solitary fibrous tumors: a clinicopathologic study of 10 cases

scientific article

High-grade soft-tissue sarcomas: tumor response assessment--pilot study to assess the correlation between radiologic and pathologic response by using RECIST and Choi criteria

scientific article published on 4 March 2009

High-risk soft tissue sarcomas treated with perioperative chemotherapy: Improving prognostic classification in a randomised clinical trial

scientific article published on 21 February 2018

Highlights in soft tissue sarcomas and gastrointestinal stromal tumours (GIST) trials reported at ASCO 2017 Annual Meeting.

scientific article published on 22 August 2017

Histology-specific nomogram for primary retroperitoneal soft tissue sarcoma

scientific article published in May 2010

Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial

scientific article

Hormonal manipulation with toremifene in sporadic desmoid-type fibromatosis.

scientific article published on 18 November 2015

How a Clinical Trial Unit can improve independent clinical research in rare tumors: the Italian Sarcoma Group experience.

scientific article published on 28 February 2017

Human equilibrative nucleoside transporter 1 gene expression is associated with gemcitabine efficacy in advanced leiomyosarcoma and angiosarcoma

scientific article published on 22 June 2017

Identification of an Actionable Mutation of KIT in a Case of Extraskeletal Myxoid Chondrosarcoma

scientific article published on 23 June 2018

Imatinib and everolimus in patients with progressing advanced chordoma: A phase 2 clinical study

scientific article published on 14 September 2018

Imatinib in advanced chordoma: A retrospective case series analysis

scientific article published on 14 August 2015

Imatinib mesylate in chordoma

scientific article

Imatinib response in two GIST patients carrying two hitherto functionally uncharacterized PDGFRA mutations: an imaging, biochemical and molecular modeling study

scientific article published in February 2011

Impact of perioperative chemotherapy and radiotherapy in patients with primary extremity soft tissue sarcoma: retrospective analysis across major histological subtypes and major reference centres

scientific article published on 29 October 2018

Leiomyosarcoma and sarcoma with myogenic differentiation

scientific article published on 19 April 2012

Localised thoracic sarcomas: outcome improvement over time at a single institution

scientific article published on 14 May 2013

Long-term Efficacy of Methotrexate Plus Vinblastine/Vinorelbine in a Large Series of Patients Affected by Desmoid-Type Fibromatosis.

scientific article published on March 2017

Long-term outcomes of pexidartinib in tenosynovial giant cell tumors

scientific article published on 16 November 2020

MRP1 overexpression determines poor prognosis in prospectively treated patients with localized high-risk soft tissue sarcoma of limbs and trunk wall: an ISG/GEIS study.

scientific article

Medical treatment of advanced chordomas

scientific article

Melan-A/MART-1 immunity in a EWS-ATF1 translocated clear cell sarcoma patient treated with sunitinib: a case report

scientific article

Molecular and biochemical analyses of platelet-derived growth factor receptor (PDGFR) B, PDGFRA, and KIT receptors in chordomas

scientific article published in December 2006

Myogenic Differentiation and Histologic Grading Are Major Prognostic Determinants in Retroperitoneal Liposarcoma

scientific article published on 01 March 2015

Myxoid/round cell and pleomorphic liposarcomas: prognostic factors and survival in a series of patients treated at a single institution

scientific article

Neoadjuvant treatment: a novel standard?

scientific article

New benchmarks to design clinical trials with advanced or metastatic liposarcoma or synovial sarcoma patients: An EORTC – Soft Tissue and Bone Sarcoma Group (STBSG) meta-analysis based on a literature review for soft-tissue sarcomas

scientific article published in 2022

New transcriptional-based insights into the pathogenesis of desmoplastic small round cell tumors (DSRCTs)

scientific article published on 22 March 2017

Nilotinib in locally advanced pigmented villonodular synovitis: a multicentre, open-label, single-arm, phase 2 trial

scientific article published on 20 March 2018

Novel intra-genic large deletions of CTNNB1 gene identified in WT desmoid-type fibromatosis

article

Patient-derived solitary fibrous tumour xenografts predict high sensitivity to doxorubicin/dacarbazine combination confirmed in the clinic and highlight the potential effectiveness of trabectedin or eribulin against this tumour.

scientific article published on 8 March 2017

Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial

scientific article published on 18 December 2018

Pazopanib in advanced vascular sarcomas: an EORTC Soft Tissue and Bone Sarcoma Group (STBSG) retrospective analysis

scientific article published on 14 November 2016

Personalizing the Approach to Retroperitoneal Soft Tissue Sarcoma: Histology-specific Patterns of Failure and Postrelapse Outcome after Primary Extended Resection

scientific article published on 10 October 2014

Pharmacological therapies for Liposarcoma

scientific article

Phase II study of imatinib in advanced chordoma

scientific article published on 13 February 2012

Phase II study on lapatinib in advanced EGFR-positive chordoma

scientific article published on 4 April 2013

Pre- and Postoperative Chemotherapy in Localized Extremity Soft Tissue Sarcoma: A European Organization for Research and Treatment of Cancer Expert Survey.

scientific article published on 30 November 2017

Preclinical and clinical evidence of activity of pazopanib in solitary fibrous tumour

scientific article published on 27 September 2014

Preoperative chemo-radiation therapy for localised retroperitoneal sarcoma: a phase I-II study from the Italian Sarcoma Group.

scientific article

Preoperative imatinib mesylate for unresectable or locally advanced primary gastrointestinal stromal tumors (GIST).

scientific article

Prolonged activity and toxicity of sirolimus in a patient with metastatic renal perivascular epithelioid cell tumor: a case report and literature review

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Quality of surgery and neoadjuvant combined therapy in the ISG-GEIS trial on soft tissue sarcomas of limbs and trunk wall.

scientific article published on 30 October 2012

Radiation Therapy as Sole Management for Solitary Fibrous Tumors (SFT): A Retrospective Study From the Global SFT Initiative in Collaboration With the Sarcoma Patients EuroNet

scientific article published on 17 April 2018

Radiation-Induced Sarcoma of the Head and Neck: A Review of the Literature

scientific article published on 17 October 2018

Receptor tyrosine kinase pathway analysis sheds light on similarities between clear-cell sarcoma and metastatic melanoma.

scientific article

Reply to Deleterious effect of ifosfamide in leiomyosarcoma: Convergence of weak signals

scientific article published on 07 August 2020

Reply to Incidence of extrameningeal solitary fibrous tumors and novel therapeutic approaches in the treatment of solitary fibrous tumors: A call for a combination therapy

scientific article published on 03 July 2020

Resectable extra-pleural and extra-meningeal solitary fibrous tumours: A multi-centre prognostic study.

scientific article

Response of conventional chondrosarcoma to gemcitabine alone: a case report

scientific article

Response to chemotherapy of solitary fibrous tumour: A retrospective study

scientific article published on 06 April 2013

Response to imatinib plus sirolimus in advanced chordoma.

scientific article published in July 2009

Response to sunitinib malate in advanced alveolar soft part sarcoma

scientific article

Response to vinorelbine and low-dose cyclophosphamide chemotherapy in two patients with desmoplastic small round cell tumor

scientific article published on November 2007

Review of past and present clinical cases with a view to future treatment options

scientific article

Sacral Chordoma: Long-term Outcome of a Large Series of Patients Surgically Treated at Two Reference Centers.

scientific article published in June 2016

Short, Full-Dose Adjuvant Chemotherapy in High-Risk Adult Soft Tissue Sarcomas: A Randomized Clinical Trial From the Italian Sarcoma Group and the Spanish Sarcoma Group

article

Short, full-dose adjuvant chemotherapy (CT) in high-risk adult soft tissue sarcomas (STS): long-term follow-up of a randomized clinical trial from the Italian Sarcoma Group and the Spanish Sarcoma Group

scientific article published on 11 October 2016

Sirolimus in Advanced Epithelioid Hemangioendothelioma: A Retrospective Case-Series Analysis from the Italian Rare Cancer Network Database.

scientific article published on 22 June 2016

Soft tissue and visceral sarcomas: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up

scientific article published on 01 October 2018

Solitary fibrous tumor of all sites: outcome of late recurrences in 14 patients.

scientific article published on 3 April 2013

Solitary fibrous tumors: loss of chimeric protein expression and genomic instability mark dedifferentiation

scientific article

Solitary fibrous tumour presenting with a single bone metastasis: report of six cases and literature review

scientific article

Sporadic extra abdominal wall desmoid-type fibromatosis: surgical resection can be safely limited to a minority of patients.

scientific article

Steroid premedication markedly reduces liver and bone marrow toxicity of trabectedin in advanced sarcoma.

scientific article

Structured myeloid cells and anti-angiogenic therapy in alveolar soft part sarcoma.

scientific article published on 27 September 2013

Sunitinib malate and figitumumab in solitary fibrous tumor: patterns and molecular bases of tumor response

scientific article

Sunitinib malate in solitary fibrous tumor (SFT) ⬇️

scientific article published on June 17, 2012

Sunitinib-induced morpho-functional changes and drug effectiveness in malignant solitary fibrous tumours

scientific article

Synovial Sarcoma: Current Concepts and Future Perspectives

scientific article published on 8 December 2017

Systemic Therapy Options for Unresectable and Metastatic Chordomas ⬇️

scientific article published on August 1, 2011

Systemic therapy for selected skull base sarcomas: Chondrosarcoma, chordoma, giant cell tumour and solitary fibrous tumour/hemangiopericytoma

scientific article published on 13 January 2016

Systemic treatment in advanced soft tissue sarcoma: what is standard, what is new.

scientific article

Systemic treatments in MDM2 positive intimal sarcoma: A multicentre experience with anthracycline, gemcitabine, and pazopanib within the World Sarcoma Network

scientific article published on 19 September 2019

Targeted therapies in rare sarcomas: IMT, ASPS, SFT, PEComa, and CCS.

scientific article published on October 2013

Tenosynovial giant cell tumour/pigmented villonodular synovitis: outcome of 294 patients before the era of kinase inhibitors.

scientific article published on 24 November 2014

The genomics of desmoplastic small round cell tumor reveals the deregulation of genes related to DNA damage response, epithelial-mesenchymal transition, and immune response

article

The impact of chemotherapy on survival of patients with extremity and trunk wall soft tissue sarcoma: revisiting the results of the EORTC-STBSG 62931 randomised trial

scientific article published on 25 January 2019

The safety and efficacy of trabectedin for the treatment of liposarcoma or leiomyosarcoma.

scientific article published on 4 April 2016

Trabectedin and olaparib in patients with advanced and non-resectable bone and soft-tissue sarcomas (TOMAS): an open-label, phase 1b study from the Italian Sarcoma Group

article

Tumor response assessment by modified Choi criteria in localized high-risk soft tissue sarcoma treated with chemotherapy

scientific article published on 17 May 2012

Tumor response to sunitinib malate observed in clear-cell sarcoma.

scientific article published on 21 January 2010

Vascular resection en-bloc with tumor removal and graft reconstruction is safe and effective in soft tissue sarcoma (STS) of the extremities and retroperitoneum

scientific article published on 07 May 2016

β-Catenin in desmoid-type fibromatosis: deep insights into the role of T41A and S45F mutations on protein structure and gene expression.

scientific article published on 19 June 2017

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