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List of works by Giuliano Ciarimboli

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Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions

scientific article
Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2

scientific article published in December 2005
Proximal Tubular Secretion of Creatinine by Organic Cation Transporter OCT2 in Cancer Patients

scientific article published on January 5, 2012
Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2

scientific article published on 17 June 2013
Role of organic cation transporters in drug-induced toxicity

scientific article published on February 1, 2011
Individual PKC-phosphorylation sites in organic cation transporter 1 determine substrate selectivity and transport regulation

scientific article published on 13 April 2005
Regulation of organic cation transport.

scientific article
Regulation of the human organic cation transporter hOCT1.

scientific article published on December 2004
Membrane transporters as mediators of cisplatin side-effects

scientific article published on January 2014
Regulation of human organic cation transporter hOCT2 by PKA, PI3K, and calmodulin-dependent kinases

scientific article (publication date: February 2003)
Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity

scientific article
Organic cation transporters

scientific article published in July 2008
New clues for nephrotoxicity induced by ifosfamide: preferential renal uptake via the human organic cation transporter 2.

scientific article published on 2 December 2010
Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule

scientific article
Cisplatin-induced renal injury is independently mediated by OCT2 and p53.

scientific article
Quantitative bioimaging of platinum in polymer embedded mouse organs using laser ablation ICP-MS.

scientific article
The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.

scientific article published on October 2002
Characterization of regulatory mechanisms and states of human organic cation transporter 2.

scientific article published on 4 January 2006
Membrane Transporters as Mediators of Cisplatin Effects and Side Effects

scientific article published on November 25, 2012
A phosphotyrosine switch regulates organic cation transporters

scientific article published on 16 March 2016
Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions

scientific article published on 6 April 2015
Calmodulin-associated post-translational regulation of rat organic cation transporter 2 in the kidney is gender dependent

scientific article published on May 2009
Substrate- and cell contact-dependent inhibitor affinity of human organic cation transporter 2: studies with two classical organic cation substrates and the novel substrate cd2+.

scientific article published on 24 June 2013
The cysteines of the extracellular loop are crucial for trafficking of human organic cation transporter 2 to the plasma membrane and are involved in oligomerization

scientific article published on 15 November 2011
Role of transporters in the distribution of platinum-based drugs

scientific article published on 24 April 2015
Rho GAP myosin IXa is a regulator of kidney tubule function

scientific article
Saving ears and kidneys from cisplatin

scientific article published on October 2013
Cystatin C in a rat model of end-stage renal failure

scientific article
Transport mechanisms and their pathology-induced regulation govern tyrosine kinase inhibitor delivery in rheumatoid arthritis

scientific article
Regulation of organic cation transport in isolated mouse proximal tubules involves complex changes in protein trafficking and substrate affinity

scientific article published on 19 June 2012
Evaluation of pharmacogenetic markers to predict the risk of Cisplatin-induced ototoxicity

scientific article published on 18 March 2014
Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity

scientific article
Laser ablation based bioimaging with simultaneous elemental and molecular mass spectrometry: towards spatially resolved speciation analysis

scientific article
The organic cation transporter 3 (OCT3) as molecular target of psychotropic drugs: transport characteristics and acute regulation of cloned murine OCT3.

scientific article published on 28 August 2013
Quantitative imaging of platinum based on laser ablation-inductively coupled plasma-mass spectrometry to investigate toxic side effects of cisplatin

scientific article published on 19 October 2015
Dynamic alterations of glomerular charge density in fixed rat kidneys suggest involvement of endothelial cell coat

scientific article
Properties and regulation of organic cation transport in freshly isolated mouse proximal tubules analyzed with a fluorescence reader-based method

scientific article published on 27 April 2011
Mitochondria act as a reservoir for the basic amine HIPDM in the lung

scientific article published on 01 November 1996
Kidney transplantation down-regulates expression of organic cation transporters, which translocate β-blockers and fluoroquinolones

scientific article published on 3 May 2013
Assessing the intracellular concentration of platinum in medulloblastoma cell lines after Cisplatin incubation.

scientific article published on 28 January 2014
Mouse organic cation transporter 1 determines properties and regulation of basolateral organic cation transport in renal proximal tubules

scientific article
Elemental Bioimaging by Means of Fast Scanning Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry.

scientific article published on 7 May 2015
Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts

scientific article
Role of albumin and glomerular capillary wall charge distribution on glomerular permselectivity: studies on the perfused-fixed rat kidney model

scientific article published on 01 November 1999
An integrative approach to cisplatin chronic toxicities in mice reveals importance of organic cation-transporter-dependent protein networks for renoprotection

scientific article published on 06 September 2019
LAPTM4A interacts with hOCT2 and regulates its endocytotic recruitment

scientific article published on 08 May 2011
Unraveling the ceramide-calpain-caspase connection in cadmium-induced apoptosis: a novel role for ceramides as activators of calpains. Focus on "Cadmium-induced ceramide formation triggers calpain-dependent apoptosis in cultured kidney proximal tubu

scientific article published on 01 August 2007
Lung tissue binding of iodobenzyl-propanediamine: involvement of beta-adrenergic receptors

scientific article
Radioreceptor assay for the measurement of endogenous digitalis-like factors using membrane particulate fraction of human placenta and 125I-digoxin: comparison with RIA method

scientific article published on 01 January 1990
Binding of 14C-furosemide to isolated human erythrocytes

scientific article published on 01 January 1989

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