List of works - Hauke Werner

A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system

scientific article published on 16 January 2013

A role for talin in presynaptic function

scientific article

A single gene defect causing claustrophobia

scientific article

Abcd2 is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice

scientific article

Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin

scientific article published on 23 January 2019

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

scientific article published on January 2017

Axonal Ensheathment in the Nervous System of Lamprey: Implications for the Evolution of Myelinating Glia

scientific article published on 25 June 2018

Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes

scientific article

CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves

scientific article published on 09 September 2020

Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

scientific article published on 11 May 2022

Cortical network dysfunction caused by a subtle defect of myelination.

scientific article

Do we have to reconsider the evolutionary emergence of myelin?

scientific article published on 15 November 2013

Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins

scientific article

Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression of Cnp1.

scientific article

Electron microscopy of myelin: Structure preservation by high-pressure freezing

scientific article published on 23 February 2016

Erratum to: Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model

scientific article published on 16 April 2013

Evolution of myelin proteolipid proteins: gene duplication in teleosts and expression pattern divergence.

scientific article

Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells

scientific article published in June 2009

Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin

scientific article published on 09 March 2020

Glial M6B stabilizes the axonal membrane at peripheral nodes of Ranvier

scientific article

Glycoprotein M6a is present in glutamatergic axons in adult rat forebrain and cerebellum

scientific article

Gpm6b deficiency impairs sensorimotor gating and modulates the behavioral response to a 5-HT2A/C receptor agonist

scientific article published on 22 April 2014

High-affinity heterotetramer formation between the large myelin-associated glycoprotein and the dynein light chain DYNLL1

scientific article published on 26 November 2018

Highlight: the 5th International Workshop on Septin Biology

scientific article

Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice

scientific journal article

Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy

scientific article published on 11 November 2021

Maintenance of high proteolipid protein level in adult central nervous system myelin is required to preserve the integrity of myelin and axons

scientific article published on 14 January 2019

Molecular cloning and transfection studies of M6b-2, a novel splice variant of a member of the PLP-DM20/M6 gene family ⬇️

scientific article published on June 15, 1998

Molecular evolution of myelin basic protein, an abundant structural myelin component

scientific article published in August 2013

Multiple splice isoforms of proteolipid M6B in neurons and oligodendrocytes.

scientific article

Mutations of Myelination-Associated Genes That Affect Axonal Integrity

article

Myelin matters: proteomic insights into white matter disorders

article

Myelin proteomics: molecular anatomy of an insulating sheath

scientific article published on 19 May 2009

Myelinating Glia-Specific Deletion of Fbxo7 in Mice Triggers Axonal Degeneration in the Central Nervous System Together with Peripheral Neuropathy

scientific article published on 13 May 2019

Myelination of the nervous system: mechanisms and functions

scientific article published on January 2014

On the evolution of myelin

scientific article published in June 2016

Partial Immunoblotting of 2D-Gels: A Novel Method to Identify Post-Translationally Modified Proteins Exemplified for the Myelin Acetylome

scientific article published on 12 January 2017

Phosphatidylinositol 4,5-bisphosphate-dependent interaction of myelin basic protein with the plasma membrane in oligodendroglial cells and its rapid perturbation by elevated calcium.

scientific article

Phylogeny of proteolipid proteins: divergence, constraints, and the evolution of novel functions in myelination and neuroprotection

scientific article published on May 2008

Progesterone antagonist therapy in a Pelizaeus-Merzbacher mouse model.

scientific article published on 27 March 2014

Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5

scientific article published on 11 March 2022

Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking

scientific article published on 22 September 2015

Proteome Profile of Myelin in the Zebrafish Brain

scientific article published on 08 April 2021

Proteome profile of peripheral myelin in healthy mice and in a neuropathy model

scientific article published on 04 March 2020

Quantitative and integrative proteome analysis of peripheral nerve myelin identifies novel myelin proteins and candidate neuropathy loci.

scientific article

Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model

scientific article

Septins in the glial cells of the nervous system

scientific article

Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia

scientific article published on 16 November 2020

Systematic approaches to central nervous system myelin.

scientific article published on 23 March 2012

Targeted inactivation of the X-linked adrenoleukodystrophy gene in mice ⬇️

scientific article published on December 1, 1997

The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2

scientific article published on 4 September 2015

The SNARE protein SNAP-29 interacts with the GTPase Rab3A: Implications for membrane trafficking in myelinating glia

scientific article

The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling

scientific article (publication date: 7 February 2003)

The septin cytoskeleton in myelinating glia.

scientific article

The transcriptome of mouse central nervous system myelin

scientific article published on 13 May 2016

Transcallosal Projections Require Glycoprotein M6-Dependent Neurite Growth and Guidance

scientific article published on 10 June 2014

Tuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPP

scientific article

Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2

scientific journal article

White matter integrity in mice requires continuous myelin synthesis at the inner tongue

scientific article published on 04 March 2022

List of works by Hauke Werner

A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system

A role for talin in presynaptic function

A single gene defect causing claustrophobia

Abcd2 is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice

Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

Axonal Ensheathment in the Nervous System of Lamprey: Implications for the Evolution of Myelinating Glia

Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes

CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves

Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

Cortical network dysfunction caused by a subtle defect of myelination.

Do we have to reconsider the evolutionary emergence of myelin?

Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins

Early ultrastructural defects of axons and axon-glia junctions in mice lacking expression of Cnp1.

Electron microscopy of myelin: Structure preservation by high-pressure freezing

Erratum to: Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model

Evolution of myelin proteolipid proteins: gene duplication in teleosts and expression pattern divergence.

Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells

Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin

Glial M6B stabilizes the axonal membrane at peripheral nodes of Ranvier

Glycoprotein M6a is present in glutamatergic axons in adult rat forebrain and cerebellum

Gpm6b deficiency impairs sensorimotor gating and modulates the behavioral response to a 5-HT2A/C receptor agonist

High-affinity heterotetramer formation between the large myelin-associated glycoprotein and the dynein light chain DYNLL1

Highlight: the 5th International Workshop on Septin Biology

Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice

Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy

Maintenance of high proteolipid protein level in adult central nervous system myelin is required to preserve the integrity of myelin and axons

Molecular cloning and transfection studies of M6b-2, a novel splice variant of a member of the PLP-DM20/M6 gene family ⬇️

Molecular evolution of myelin basic protein, an abundant structural myelin component

Multiple splice isoforms of proteolipid M6B in neurons and oligodendrocytes.

Mutations of Myelination-Associated Genes That Affect Axonal Integrity

Myelin matters: proteomic insights into white matter disorders

Myelin proteomics: molecular anatomy of an insulating sheath

Myelinating Glia-Specific Deletion of Fbxo7 in Mice Triggers Axonal Degeneration in the Central Nervous System Together with Peripheral Neuropathy

Myelination of the nervous system: mechanisms and functions

On the evolution of myelin

Partial Immunoblotting of 2D-Gels: A Novel Method to Identify Post-Translationally Modified Proteins Exemplified for the Myelin Acetylome

Phosphatidylinositol 4,5-bisphosphate-dependent interaction of myelin basic protein with the plasma membrane in oligodendroglial cells and its rapid perturbation by elevated calcium.

Phylogeny of proteolipid proteins: divergence, constraints, and the evolution of novel functions in myelination and neuroprotection

Progesterone antagonist therapy in a Pelizaeus-Merzbacher mouse model.

Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5

Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking

Proteome Profile of Myelin in the Zebrafish Brain

Proteome profile of peripheral myelin in healthy mice and in a neuropathy model

Quantitative and integrative proteome analysis of peripheral nerve myelin identifies novel myelin proteins and candidate neuropathy loci.

Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model

Septins in the glial cells of the nervous system

Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia

Systematic approaches to central nervous system myelin.

Targeted inactivation of the X-linked adrenoleukodystrophy gene in mice ⬇️

The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2

The SNARE protein SNAP-29 interacts with the GTPase Rab3A: Implications for membrane trafficking in myelinating glia

The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling

The septin cytoskeleton in myelinating glia.

The transcriptome of mouse central nervous system myelin

Transcallosal Projections Require Glycoprotein M6-Dependent Neurite Growth and Guidance

Tuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPP

Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2

White matter integrity in mice requires continuous myelin synthesis at the inner tongue