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List of works by Wiebke Möbius

A TNF-regulated recombinatorial macrophage immune receptor implicated in granuloma formation in tuberculosis

scientific article

A critical role for the cholesterol-associated proteolipids PLP and M6B in myelination of the central nervous system

scientific article published on 16 January 2013

A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes

scientific article published on 01 June 2019

A role for myelin-associated peroxisomes in maintaining paranodal loops and axonal integrity

scientific article published in 2011

A role of oligodendrocytes in information processing

scientific article published on 30 October 2020

A vaccinia virus lacking A10L: viral core proteins accumulate on structures derived from the endoplasmic reticulum.

scientific article published on March 2006

Analysis of the Serotonergic System in a Mouse Model of Rett Syndrome Reveals Unusual Upregulation of Serotonin Receptor 5b

scientific article published on 08 March 2017

Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin

scientific article published on 23 January 2019

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

scientific article published on January 2017

Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination

scientific article

Arabidopsis sterol endocytosis involves actin-mediated trafficking via ARA6-positive early endosomes

scientific article published in August 2003

Aspartoacylase-lacZ knockin mice: an engineered model of Canavan disease

scientific article

Axonal Ensheathment in the Nervous System of Lamprey: Implications for the Evolution of Myelinating Glia

scientific article published on 25 June 2018

Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination

scientific article published on 2 November 2011

Beta-amyloid peptide variants in brains and cerebrospinal fluid from amyloid precursor protein (APP) transgenic mice: comparison with human Alzheimer amyloid

scientific article

CMTM6 expressed on the adaxonal Schwann cell surface restricts axonal diameters in peripheral nerves

scientific article published on 09 September 2020

Cholesterol regulates the endoplasmic reticulum exit of the major membrane protein P0 required for peripheral myelin compaction.

scientific article published in May 2009

Concentration of rafts in platelet filopodia correlates with recruitment of c-Src and CD63 to these domains

scientific article published in June 2003

Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

scientific article published on 11 May 2022

Cortical network dysfunction caused by a subtle defect of myelination.

scientific article

Critical time window of neuronal cholesterol synthesis during neurite outgrowth.

scientific article published in May 2012

Cryo FIB-SEM: volume imaging of cellular ultrastructure in native frozen specimens

scientific article

Cryopreparation of biological specimens for immunoelectron microscopy

scientific article

Defective cholesterol clearance limits remyelination in the aged central nervous system

scientific article published on 4 January 2018

Dietary cholesterol promotes repair of demyelinated lesions in the adult brain

scientific article published on 24 January 2017

Drosophila auditory organ genes and genetic hearing defects

scientific article published in August 2012

Electron microscopy of myelin: Structure preservation by high-pressure freezing

scientific article published on 23 February 2016

Electron microscopy of the mouse central nervous system

scientific article published on January 2010

Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.

scientific article published in June 2010

Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination

scientific article published on 9 May 2016

Exosome secretion ameliorates lysosomal storage of cholesterol in Niemann-Pick type C disease

scientific article published on 16 June 2010

Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation

scientific article

Gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking

scientific article

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

scientific article

High cholesterol level is essential for myelin membrane growth

scientific article published on 27 March 2005

Identification of Tmem10/Opalin as an oligodendrocyte enriched gene using expression profiling combined with genetic cell ablation

scientific article

Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O.

scientific article

Inhibition of CNS remyelination by the presence of semaphorin 3A.

scientific article

Internalization routes of cell-penetrating melanoma antigen peptides into human dendritic cells

scientific article published on January 2014

Intranasal mesenchymal stem cell therapy to boost myelination after encephalopathy of prematurity

scientific article published on 12 October 2020

Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases

scientific article published on 22 June 2016

Loss of electrostatic cell-surface repulsion mediates myelin membrane adhesion and compaction in the central nervous system

scientific article published on 4 February 2013

MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation

scientific article published on 22 June 2020

Macromolecular and electrical coupling between inner hair cells in the rodent cochlea

scientific article published on 25 June 2020

Maintenance of high proteolipid protein level in adult central nervous system myelin is required to preserve the integrity of myelin and axons

scientific article published on 14 January 2019

Mechanics of individual keratin bundles in living cells

scientific article

Mechanism of spindle pole organization and instability in human oocytes

scientific article published in 2022

Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis

scientific article published on 21 December 2020

Modulation of cellular cholesterol transport and homeostasis by Rab11.

scientific article

Monitoring ATP dynamics in electrically active white matter tracts

scientific article published on 17 April 2017

Mutual effects of caveolin and nerve growth factor signaling in pig oligodendrocytes

scientific article published in February 2010

Myelin basic protein-dependent plasma membrane reorganization in the formation of myelin

scientific article

Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue

scientific article published on January 2014

Myelinated mouse nerves studied by X-ray phase contrast zoom tomography

scientific article published on 3 November 2015

Myelinating Glia-Specific Deletion of Fbxo7 in Mice Triggers Axonal Degeneration in the Central Nervous System Together with Peripheral Neuropathy

scientific article published on 13 May 2019

NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies

scientific article published on 01 April 2019

Neonatal hyperoxia exposure disrupts axon-oligodendrocyte integrity in the subcortical white matter

scientific article published on May 2013

Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication

scientific article

Oligodendrocyte ablation triggers central pain independently of innate or adaptive immune responses in mice

scientific article

Oligodendrocyte-encoded Kir4.1 function is required for axonal integrity

scientific article published on 11 September 2018

Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?

scientific article

Oligodendrocytes support axonal transport and maintenance via exosome secretion

scientific article published on 22 December 2020

Partial Immunoblotting of 2D-Gels: A Novel Method to Identify Post-Translationally Modified Proteins Exemplified for the Myelin Acetylome

scientific article published on 12 January 2017

Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy

scientific article published on 4 May 2017

Phylogeny of proteolipid proteins: divergence, constraints, and the evolution of novel functions in myelination and neuroprotection

scientific article published on May 2008

Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5

scientific article published on 11 March 2022

Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

scientific journal article

Proteolipid protein modulates preservation of peripheral axons and premature death when myelin protein zero is lacking

scientific article published on 22 September 2015

Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation

scientific article

Publisher Correction: NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies

scientific article published on 16 April 2019

Quantitative and integrative proteome analysis of peripheral nerve myelin identifies novel myelin proteins and candidate neuropathy loci.

scientific article

Recycling Compartments and the Internal Vesicles of Multivesicular Bodies Harbor Most of the Cholesterol Found in the Endocytic Pathway ⬇️

scientific article published on April 1, 2003

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C.

scientific article

Seeding variability of different alpha synuclein strains in synucleinopathies

scientific article published on 27 March 2019

Septin/anillin filaments scaffold central nervous system myelin to accelerate nerve conduction

scientific article published on 9 August 2016

Structural myelin defects are associated with low axonal ATP levels but rapid recovery from energy deprivation in a mouse model of spastic paraplegia

scientific article published on 16 November 2020

Survival of adult neurons lacking cholesterol synthesis in vivo

scientific article

Targeting myelin lipid metabolism as a potential therapeutic strategy in a model of CMT1A neuropathy

scientific article published in Nature Communications

The MICOS component Mic60 displays a conserved membrane-bending activity that is necessary for normal cristae morphology

scientific article published on 2 March 2017

The cytoskeletal adapter protein 4.1G organizes the internodes in peripheral myelinated nerves

scientific article published on 30 January 2012

Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia

scientific article

Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet

Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain.

scientific article published in September 2013

Transport of the major myelin proteolipid protein is directed by VAMP3 and VAMP7

Tuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPP

scientific article

Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS

scientific article published on 22 October 2019

Uncoupling of neuroinflammation from axonal degeneration in mice lacking the myelin protein tetraspanin-2

scientific journal article

White matter integrity in mice requires continuous myelin synthesis at the inner tongue

scientific article published on 04 March 2022

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