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List of works by Jean-Pierre Hugot

12-month follow-up after successful infliximab therapy in pediatric crohn disease

scientific article published on 01 March 2008

A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system

scientific article

A heterozygous endothelin 3 mutation in Waardenburg-Hirschsprung disease: is there a dosage effect of EDN3/EDNRB gene mutations on neurocristopathy phenotypes?

scientific article published in March 2001

A prospective study of the efficacy and tolerance of a chimeric antibody to tumor necrosis factors (remicade) in severe pediatric crohn disease.

scientific article

Abnormal activation of autophagy-induced crinophagy in Paneth cells from patients with Crohn's disease

scientific article published on 28 January 2012

Altered gut microbiota composition in immune-impaired Nod2(-/-) mice

article

Analysis of Genes Associated with Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn's disease.

scientific article published on 28 February 2018

Analysis of single nucleotide polymorphisms in the region of CLDN2-MORC4 in relation to inflammatory bowel disease

scientific article published on August 2013

Analysis of theNF2 tumor-suppressor gene and of chromosome 22 deletions in gliomas

article

Antineutrophil cytoplasmic antibodies in children with inflammatory bowel disease: prevalence and diagnostic value

scientific article published on 01 August 1997

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

scientific article (publication date: 31 May 2001)

CARD 15 gene mutations in sarcoidosis.

scientific article published in April 2005

CARD15 mutations are rare in Swedish pediatric Crohn disease

scientific article published on 01 April 2005

CARD15/NOD2 analyses in spondylarthropathy

scientific article published on 01 May 2002

CARD15/NOD2 is not a predisposing factor for necrotizing enterocolitis

scientific article published on 01 September 2005

CARD15/NOD2 is required for Peyer's patches homeostasis in mice

scientific article

CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease

scientific article published on March 2002

CARD15/NOD2 mutations in Crohn's disease

scientific article

Celiac disease in the Mediterranean area.

scientific article

Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting Proteins

scientific article

Characterization of Crohn disease in X-linked inhibitor of apoptosis-deficient male patients and female symptomatic carriers.

scientific article published on 15 June 2014

Characterization of the Mycobacterium avium subsp. paratuberculosis laminin-binding/histone-like protein (Lbp/Hlp) which reacts with sera from patients with Crohn’s disease

scientific article published on 18 February 2011

Chronic intestinal pseudo-obstruction and delayed myenteric ganglion cell maturation

scientific article published on 01 October 1992

Clinical characteristics of Crohn's disease in 72 families

scientific article published on 01 September 1996

Clustering of Crohn's disease within affected sibships

scientific article published on 01 February 2003

Combined Immunodeficiency in Patients With Trichohepatoenteric Syndrome.

scientific article

Combined NADPH oxidase 1 and interleukin 10 deficiency induces chronic endoplasmic reticulum stress and causes ulcerative colitis-like disease in mice

scientific article

Common variants at five new loci associated with early-onset inflammatory bowel disease

scientific article

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

scientific article published on 17 July 2019

Complementary Roles of Nod2 in Hematopoietic and Nonhematopoietic Cells in Preventing Gut Barrier Dysfunction Dependent on MLCK Activity.

scientific article

Congenital Sodium Diarrhea by mutation of the SLC9A3 gene

scientific article published on 02 July 2019

Consensus guidelines of ECCO/ESPGHAN on the medical management of pediatric Crohn's disease.

scientific article

Crohn disease--associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae

scientific article

Crohn's disease and early exposure to domestic refrigeration

scientific article published in 2009

Crohn's disease: the cold chain hypothesis.

scientific article

Defective IL10 signaling defining a subgroup of patients with inflammatory bowel disease.

scientific article published on 26 April 2011

Diagnostic Yield of Next-generation Sequencing in Very Early-onset Inflammatory Bowel Diseases: A Multicentre Study

scientific article published on 01 August 2018

Differential expression and regulation of ADAM17 and TIMP3 in acute inflamed intestinal epithelia

scientific article published on 19 March 2009

Digestive perianastomotic ulcerations and Crohn's disease

scientific article published on 06 August 2014

Early Arthritis Is Associated With Failure of Immunosuppressive Drugs and Severe Pediatric Crohn's Disease Evolution

scientific article published on 01 October 2018

Epidemiology and genetics of chronic inflammatory bowel disease

scientific article published in January 1998

Estimating the odds ratios of Crohn disease for the main CARD15/NOD2 mutations using a conditional maximum likelihood method in pedigrees collected via affected family members

scientific article published on 25 April 2007

Factors influencing outcome after intestinal transplantation in children

scientific article published on 01 July 2006

Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases.

scholarly article

Genetic analyses of chromosome 12 loci in Crohn's disease.

scientific article published in December 2000

Genetic characterization of congenital tufting enteropathy: epcam associated phenotype and involvement of SPINT2 in the syndromic form

scientific article published on 19 October 2013

Genetic refinement and physical mapping of a chromosome 16q candidate region for inflammatory bowel disease

scientific article published on 01 October 2001

Genetic susceptibility factors in a cohort of 38 patients with SAPHO syndrome: a study of PSTPIP2, NOD2, and LPIN2 genes

scientific article published on 23 December 2009

Genetic susceptibility to a complex disease: the key role of functional redundancy.

scientific article published in January 2011

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

scientific article

Genome-wide scanning in inflammatory bowel diseases.

scientific article

Genotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms

scientific article

Growth and Adult Height in Patients with Crohn's Disease Treated with Anti-Tumor Necrosis Factor α Antibodies

scientific article

Gut Microbiota Diversity and Human Diseases: Should We Reintroduce Key Predators in Our Ecosystem?

scientific article

HLA-DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease.

scientific article

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.

scientific article

Ileal involvement is age dependent in pediatric Crohn's disease

scientific article published on 01 July 2005

In situ Rantes and interferon-gamma gene expression in pediatric small bowel Crohn's disease

scientific article published on 01 October 1997

Incidence of autoimmune diseases in celiac disease: protective effect of the gluten-free diet.

scientific article

Increased Proliferation of the Ileal Epithelium as a Remote Effect of Ulcerative Colitis.

scientific article

Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease

scientific article

Infevers: an evolving mutation database for auto-inflammatory syndromes

scientific article published on September 2004

Inflammatory Bowel Diseases: the genetic revolution.

scientific article published in June 2009

Inflammatory bowel disease after allogeneic stem cell transplantation

scientific article published on 8 June 2015

Inflammatory bowel disease: causes and consequences

scientific article published on 01 June 2004

Inflammatory bowel diseases: the paediatric gastroenterologist's perspective.

scientific article published on 25 September 2007

Infliximab Paradoxical Psoriasis in a Cohort of Children With Inflammatory Bowel Disease

scientific article published on 01 August 2019

Integrative Network-based Analysis of Colonic Detoxification Gene Expression in Ulcerative Colitis According to Smoking Status

scientific article

Intestinal barrier dysfunction triggered by invasive bacteria

scientific article published on 14 January 2014

Intractable infant diarrhea with epithelial dysplasia associated with polymalformation

scientific article published on 01 September 1998

Is Crohn's Disease the Price to Pay Today for Having Survived the Black Death?

scientific article published on 01 September 2019

Is intestinal transplantation the future of children with definitive intestinal insufficiency?

scientific article published on 20 November 2008

Karyotype diversity suggests that Laonastes aenigmamus (Laotian rock rat) (Rodentia, Diatomyidae) is a multi-specific genus.

scientific article

Lack of association between CARD15 gene polymorphisms and hidradenitis suppurativa: a pilot study

scientific article published on 01 January 2007

Linkage analyses of chromosome 6 loci, including HLA, in familial aggregations of Crohn disease

scientific article published on 01 August 1994

Long-term outcome, growth and digestive function in children 2 to 18 years after intestinal transplantation

scientific article

Loss-of-Function Mutations in UNC45A Cause a Syndrome Associating Cholestasis, Diarrhea, Impaired Hearing, and Bone Fragility.

scientific article published in February 2018

Macrophages Inability to Mediate Adherent-Invasive E. coli Replication is Linked to Autophagy in Crohn's Disease Patients

scientific article published on 05 November 2019

Management of Paediatric Patients With Medically Refractory Crohn's Disease Using Ustekinumab: A Multi-Centred Cohort Study

scientific article published on 01 April 2019

Management of pediatric ulcerative colitis: joint ECCO and ESPGHAN evidence-based consensus guidelines

scientific article published on September 2012

Mapping of a susceptibility locus for Crohn's disease on chromosome 16

scientific article

Medication in infectious acute diarrhea in children

scientific article published in October 2007

Medullary thyroid carcinoma identified within the first year of life in children with hereditary multiple endocrine neoplasia type 2A (codon 634) and 2B.

scientific article published on 24 February 2009

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Microbial induction of CARD15 expression in intestinal epithelial cells via toll-like receptor 5 triggers an antibacterial response loop

scientific article published on 01 November 2006

Microvillous atrophy: atypical presentations

scientific article published in December 2014

Microvillous inclusion disease: how to improve the prognosis of a severe congenital enterocyte disorder.

scientific article published in April 2011

Molecular cloning and characterization of a rat intestinal sucrase-isomaltase cDNA. Regulation of sucrase-isomaltase gene expression by sucrose feeding.

scientific article published on September 1990

Molecular reclassification of Crohn's disease: a cautionary note on population stratification

scientific article (publication date: 2013)

Monocyte-derived macrophages from Crohn's disease patients are impaired in the ability to control intracellular adherent-invasive Escherichia coli and exhibit disordered cytokine secretion profile.

scientific article published on 24 March 2015

Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin

scientific article

NOD2 Expression in Intestinal Epithelial Cells Protects Toward the Development of Inflammation and Associated Carcinogenesis

scientific article published on 23 October 2018

NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation

scientific article published on 16 June 2009

NOD2/CARD15 does not influence response to infliximab in Crohn's disease

article

NOD2/CARD15 gene mutations in North Algerian patients with inflammatory bowel disease

scientific article published in July 2015

NOD2: a potential target for regulating liver injury

scientific article published on 28 January 2008

Network Modeling of Crohn's Disease Incidence

scientific article

Nod2 Deficiency Leads to a Specific and Transmissible Mucosa-associated Microbial Dysbiosis Which Is Independent of the Mucosal Barrier Defect.

scientific article

Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice

scientific article

Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches.

scientific article published on 15 October 2009

Nod2: The intestinal gate keeper.

scientific article

PPAR and Crohn's disease: another piece of the puzzle?

scientific article published on 01 February 2005

Pancreatic involvement in inflammatory bowel diseases in children

scientific article

Peyer's Patches: The Immune Sensors of the Intestine.

scientific article

Plummer-Vinson Syndrome in Children

scientific article published in November 2015

Preliminary note: Talpa aquitania nov. sp. (Talpidae, Soricomorpha) a new mole species from southwest France and north Spain

scientific article published in 2015

Prevalence of CARD15/NOD2 mutations in Caucasian healthy people

scientific article

Prevalence of Species in the Ileum of Crohn's Disease Patients and Controls

scientific article published on 21 September 2018

Prolonged enteral feeding is often required to avoid long-term nutritional and metabolic complications after esophagogastric dissociation

scientific article published on 01 March 2010

Pseudomonas fluorescens alters the intestinal barrier function by modulating IL-1β expression through hematopoietic NOD2 signaling.

scientific article published on March 2015

RIP2 polymorphisms in inflammatory bowel diseases.

scientific article

Recurrent autoimmune pancreatitis in a 10-year-old boy

scientific article published on 01 March 2009

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

scientific article

Respective Roles of Hematopoietic and Nonhematopoietic Nod2 on the Gut Microbiota and Mucosal Homeostasis

scientific article

Results of the Paris Program: Ten Years of Pediatric Intestinal Transplantation

scientific article published on 01 May 2005

SKIV2L mutations cause syndromic diarrhea, or trichohepatoenteric syndrome.

scientific article published on 22 March 2012

Serum antibodies to Mycobacterium avium subspecies paratuberculosis combined with anti-Saccharomyces cerevisiae antibodies in Crohn's disease patients: prevalence and diagnostic role.

scientific article published on 8 January 2011

Severe dysimmune cytopenia in children treated with tacrolimus after organ transplantation.

scientific article

Significant linkage to spondyloarthropathy on 9q31-34

scientific article published on 01 August 2004

Sporadic Blau syndrome with a double CARD15 mutation. Report of a case with lifelong follow-up

scientific article published on 01 October 2004

Sur le genre Trypanoxyuris (Oxyuridae, Nematoda) IV. Sous-genre Trypanoxyuris parasite de Primates Cebidae et Atelidae (suite) Étude morphologique de Trypanoxyuris callicebi n. sp.

scientific article published in 1985

Surgical Management of Crohn Disease in Children: Guidelines From the Paediatric IBD Porto Group of ESPGHAN.

scientific article published on 6 March 2017

TNFSF15 polymorphisms are associated with susceptibility to inflammatory bowel disease in a new European cohort

scientific article published on 13 January 2009

Tacrolimus Exerts Only a Transient Effectiveness in Refractory Pediatric Crohn Disease: A Case Series

scientific article published on 16 July 2016

Talpa aquitania sp. nov. (Talpidae, Soricomorpha), a new mole species from SW France and N Spain ⬇️

scientific article published in 2017

The IBD International Genetics Consortium Provides Further Evidence for Linkage to IBD4 and Shows Gene-Environment Interaction

article

The NLR gene family: a standard nomenclature

scientific article

The NOD2-RICK complex signals from the plasma membrane.

scientific article published on 13 March 2007

Trace-element deficiencies in microvillous inclusion disease

scientific article published on 01 May 2012

Treatments for pediatric achalasia: Heller myotomy or pneumatic dilatation?

scientific article published on 29 March 2010

Trough Levels of Infliximab at Week 6 Are Predictive of Remission at Week 14 in Pediatric Crohn's Disease

scientific article published on 01 March 2020

Two distinct deleted regions on the short arm of chromosome I in neuroblastoma

scientific article published on 01 August 1994

Ultrasonographic assessment of inflammatory bowel disease in children: comparison with ileocolonoscopy

scientific article published on 01 January 1997

Unusual feature of neonatal hypernatremic dehydration due to microvillus inclusion disease: a case report

scientific article published on 11 June 2018

Update on genetics of inflammatory bowel disease

scientific article published on 01 July 2002

Which Environmental Factors Cause IBD Relapses?

scientific article

Yersinia pseudotuberculosis disrupts intestinal barrier integrity through hematopoietic TLR-2 signaling.

scientific article published on 8 May 2012

Yersinia pseudotuberculosis effector YopJ subverts the Nod2/RICK/TAK1 pathway and activates caspase-1 to induce intestinal barrier dysfunction.

scientific article

[Arthropathies following the administration of pefloxacin to an adolescent with mucoviscidosis]

scientific article

[Chronic inflammatory bowel diseases in the child: clinical aspects]

scientific article published on 01 January 1998

[Diarrhea in children]

scientific article published on 01 February 1998

[Failure to thrive and intestinal diseases in congenital disorders of glycosylation]

scientific article published on 01 July 2003

[Genetic epidemiology and therapeutic approach of inflammatory diseases of the digestive tract]

scientific article published on 01 January 1996

[Genetics of Crohn disease: a complex model]

scientific article published on 01 January 1996

[Genetics of inflammatory bowel diseases]

scientific article published on 01 November 1995

[Hemorrhagic ascites revealing duodenal duplication]

scientific article published on 27 February 2009

[Low bone mineral density in children with Crohn's disease]

scientific article published on 01 July 2004

[New therapeutic approaches in Crohn's disease]

scientific article published on 01 May 2001

[Role of NOD2 gene in Crohn's disease]

scientific article published on 01 January 2002

[Treatment of Crohn disease in children]

scientific article published on 01 January 1996

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