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List of works by Jean-Antoine Girault

A molecular view on paranodal junctions of myelinated fibers.

scientific article

A novel mechanism by which reward and drugs of abuse alter chromatin in neurons

scientific article

A phosphatase cascade by which rewarding stimuli control nucleosomal response

scientific article

A translational systems biology approach in both animals and humans identifies a functionally related module of accumbal genes involved in the regulation of reward processing and binge drinking in males.

scientific article published on 11 December 2015

ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain

scientific article published in January 1990

ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro

scientific article published in May 1989

Activation of the bilateral corticostriatal glutamatergic projection by infusion of GABA into thalamic motor nuclei in the cat: an in vivo release study.

scientific article published on January 1989

Acute drug-induced spine changes in the nucleus accumbens are dependent on β-adducin.

scientific article published on 29 July 2016

Adaptive reaction of nigral neurons following lesion of their ventromedial-thalamic projection field

scientific article published in June 1984

Addictive and non-addictive drugs induce distinct and specific patterns of ERK activation in mouse brain.

scientific article published in April 2004

Adenylate cyclase 1 as a key actor in the refinement of retinal projection maps.

scientific article published in March 2003

Alternative splicing controls the mechanisms of FAK autophosphorylation

scientific journal article

Alternatively spliced focal adhesion kinase in rat brain with increased autophosphorylation activity

scientific article published in November 1997

Apomorphine and haloperidol effects on striatal 3H-dopamine release in anesthetized, awake restrained and freely moving rats

scientific article published in February 1986

Association of Caspr/paranodin with tumour suppressor schwannomin/merlin and beta1 integrin in the central nervous system

scientific article

Association of TAG-1 with Caspr2 is essential for the molecular organization of juxtaparanodal regions of myelinated fibers

scientific article

Autophosphorylation of Tyr397 and its phosphorylation by Src-family kinases are altered in focal-adhesion-kinase neuronal isoforms

scientific article published on May 2000

Autophosphorylation-independent and -dependent functions of focal adhesion kinase during development

scientific article published on 23 September 2009

Axones et cellules de Schwann… si loin, si proches

scientific article published on 28 November 2008

Bilateral cerebral metabolic alterations following lesion of the ventromedial thalamic nucleus: mapping by the 14C-deoxyglucose method in conscious rats

scientific article published in January 1985

Calcineurin is essential for depolarization-induced nuclear translocation and tyrosine phosphorylation of PYK2 in neurons

scientific article published on 07 August 2007

Cannabinoids activate p38 mitogen-activated protein kinases through CB1 receptors in hippocampus

scientific article

Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II.

scientific article

Characterization of dopamine D1 and D2 receptor-expressing neurons in the mouse hippocampus.

scientific article published on 6 July 2012

Characterization of the interaction between DARPP-32 and protein phosphatase 1 (PP-1): DARPP-32 peptides antagonize the interaction of PP-1 with binding proteins

scientific article

Chronic treatment of rats with SCH-23390 or raclopride does not affect the concentrations of DARPP-32 or its mRNA in dopamine-innervated brain regions

scientific article published in July 1990

Cocaine conditioned place preference: unexpected suppression of preference due to testing combined with strong conditioning.

scientific article published on 10 January 2018

Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease

scientific article published on 30 January 2019

Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells.

scientific article

Contacts cellulaires des fibres myélinisées du système nerveux périphérique

scientific article published on 01 February 2005

Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia

scientific article published in June 2007

Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation.

scientific article published on 4 November 2010

Cyclin-Dependent Kinase 5 Dysfunction Contributes to Depressive-like Behaviors in Huntington's Disease by Altering the DARPP-32 Phosphorylation Status in the Nucleus Accumbens

scientific article published on 13 March 2019

DARPP-32 binds to tra2-beta1 and influences alternative splicing.

scientific article

DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons

scientific article

DARPP-32 is a robust integrator of dopamine and glutamate signals

scientific article

DARPP-32: an integrator of neurotransmission

scientific article published on January 2004

DARPP-32: molecular integration of phosphorylation potential.

scientific article published on July 2008

Delayed, context- and dopamine D1 receptor-dependent activation of ERK in morphine-sensitized mice

scientific article published on 3 June 2008

Dendritic diameter influences the rate and magnitude of hippocampal cAMP and PKA transients during β-adrenergic receptor activation

scientific article published on 11 August 2016

Dendritic geometry shapes neuronal cAMP signalling to the nucleus

scientific article

Dephosphorylation of Ser-137 in DARPP-32 by protein phosphatases 2A and 2C: different roles in vitro and in striatonigral neurons

scientific article published on February 1998

Depolarization activates ERK and proline-rich tyrosine kinase 2 (PYK2) independently in different cellular compartments in hippocampal slices

scientific journal article

Depolarization and neurotransmitters increase neuronal protein tyrosine phosphorylation

scientific article

Development of nodes of Ranvier

scientific article

Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons

scientific article published on 20 May 2013

Differential expression of ARPP-16 and ARPP-19, two highly related cAMP-regulated phosphoproteins, one of which is specifically associated with dopamine-innervated brain regions

scientific journal article

Differential regulation of Cdc2 and Aurora-A in Xenopus oocytes: a crucial role of phosphatase 2A.

scientific article published in June 2005

Differential regulation of FAK+ and PYK2/Cakbeta, two related tyrosine kinases, in rat hippocampal slices: effects of LPA, carbachol, depolarization and hyperosmolarity

scientific article published in May 1998

Differential regulation of proline-rich tyrosine kinase 2/cell adhesion kinase beta (PYK2/CAKbeta) and pp125(FAK) by glutamate and depolarization in rat hippocampus

scientific article

Distribution and compartmental organization of GABAergic medium-sized spiny neurons in the mouse nucleus accumbens.

scientific article published on 19 February 2013

Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.

scientific article published on September 1992

Dopamine D1 agonist SKF 38393 increases the state of phosphorylation of ARPP-21 in substantia nigra

scientific article published in March 1993

Dopamine D2 receptors gate generalization of conditioned threat responses through mTORC1 signaling in the extended amygdala

scientific article

Drugs of abuse, protein phosphatases, and ERK pathway

scientific article published in May 2005

Dual role of Fyn in the regulation of FAK+6,7 by cannabinoids in hippocampus

scientific article published on 23 July 2001

ERK2: a logical AND gate critical for drug-induced plasticity?

scientific article published on 7 November 2006

Effects of riluzole on N-methyl-D-aspartate-induced tyrosine phosphorylation in the rat hippocampus.

scientific article published in June 2001

Enhancement of glutamate release in the rat striatum following electrical stimulation of the nigrothalamic pathway

scientific article published in May 1986

Essential role of oligodendrocytes in the formation and maintenance of central nervous system nodal regions.

scientific article published in December 2001

Excitatory amino acid antagonists and Parkinson's disease

scientific article published in August 1990

Ezrin interacts with focal adhesion kinase and induces its activation independently of cell-matrix adhesion

scientific article published on 23 July 2001

F3/contactin, a neuronal cell adhesion molecule implicated in axogenesis and myelination.

scientific article

FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3.

scientific article

FAK and PYK2/CAKbeta in the nervous system: a link between neuronal activity, plasticity and survival?

scientific article

FAK dimerization controls its kinase-dependent functions at focal adhesions

scientific article

FAK+ and PYK2/CAKbeta, two related tyrosine kinases highly expressed in the central nervous system: similarities and differences in the expression pattern

scientific journal article

Fluorescence-activated sorting of fixed nuclei: a general method for studying nuclei from specific cell populations that preserves post-translational modifications.

scientific article published in April 2014

Focal Adhesion Kinase in Rat Central Nervous System

scientific article published on 01 August 1995

Focal adhesion kinase pp125FAK interacts with the large conductance calcium-activated hSlo potassium channel in human osteoblasts: potential role in mechanotransduction.

scientific article published on October 2003

Focal adhesion kinase splice variants maintain primitive acute myeloid leukemia cells through altered Wnt signaling.

scientific article

Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum

scientific article published on 23 April 2020

G(olf) and Gs in rat basal ganglia: possible involvement of G(olf) in the coupling of dopamine D1 receptor with adenylyl cyclase

scientific article

Galpha(olf) levels are regulated by receptor usage and control dopamine and adenosine action in the striatum

scientific journal article

Gene expression analyses identify Narp contribution in the development of L-DOPA-induced dyskinesia

scientific article published on January 2015

Genetic variants in autism-related CNTNAP2 impair axonal growth of cortical neurons

scholarly article by Giorgia Canali et al published 21 March 2018 in Human Molecular Genetics

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Ghrelin and food reward

scientific article published on 05 January 2019

Glutamate Counteracts Dopamine/PKA Signaling via Dephosphorylation of DARPP-32 Ser-97 and Alteration of Its Cytonuclear Distribution

scientific article

Glutamate-dependent phosphorylation of elongation factor-2 and inhibition of protein synthesis in neurons.

scientific article published on May 1997

Growth factor activity of endothelin-1 in primary astrocytes mediated by adhesion-dependent and -independent pathways

scientific article published in August 1997

Gα(olf) mutation allows parsing the role of cAMP-dependent and extracellular signal-regulated kinase-dependent signaling in L-3,4-dihydroxyphenylalanine-induced dyskinesia.

scientific article

Haloperidol promotes mTORC1-dependent phosphorylation of ribosomal protein S6 via dopamine- and cAMP-regulated phosphoprotein of 32 kDa and inhibition of protein phosphatase-1.

scientific article published on 3 May 2013

Haloperidol regulates the state of phosphorylation of ribosomal protein S6 via activation of PKA and phosphorylation of DARPP-32

scientific article

Haloperidol-induced Nur77 expression in striatopallidal neurons is under the control of protein phosphatase 1 regulation by DARPP-32.

scientific article published on 15 January 2014

Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons

scientific article

Heterozygous Gnal Mice Are a Novel Animal Model with Which to Study Dystonia Pathophysiology.

scientific article published on 25 May 2017

Histone H3 phosphorylation is under the opposite tonic control of dopamine D2 and adenosine A2A receptors in striatopallidal neurons.

scientific article published on 21 January 2009

Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A.

scientific article published on November 1998

How can drug discovery for psychiatric disorders be improved?

scientific article published in March 2007

How to awaken your nanomachines: Site-specific activation of focal adhesion kinases through ligand interactions

scientific article published on 17 June 2015

Immunocytochemical localization of phosphatase inhibitor-1 in rat brain

scientific article published on August 1991

Improving the quality of immunoblots by chromatography of polyclonal antisera on keratin affinity columns

scientific article published on 01 October 1989

In vivo release of [3H]gamma-aminobutyric acid in the rat neostriatum--I. Characterization and topographical heterogeneity of the effects of dopaminergic and cholinergic agents

scientific article published on December 1986

In vivo release of [3H]gamma-aminobutyric acid in the rat neostriatum--II. Opposing effects of D1 and D2 dopamine receptor stimulation in the dorsal caudate putamen

scientific article published on December 1986

In vivo release of endogenous amino acids from the rat striatum: further evidence for a role of glutamate and aspartate in corticostriatal neurotransmission

scientific article published in July 1986

Integrating neurotransmission in striatal medium spiny neurons.

scientific article published on January 2012

Janus kinases and focal adhesion kinases play in the 4.1 band: a superfamily of band 4.1 domains important for cell structure and signal transduction

scientific article

L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice

scientific article published in February 2009

Lack of change in striatal DARPP-32 levels following nigrostriatal dopaminergic lesions in animals and in parkinsonian syndromes in man.

scientific article published in January 1990

Local cerebral metabolic effects induced by nigral stimulation following ventromedial thalamic lesions. I: Basal ganglia and related motor structures

scientific article published in June 1984

Local cerebral metabolic effects induced by nigral stimulation following ventromedial thalamic lesions. II: Sensory motor, reticular and limbic systems

scientific article published in April 1985

Localization of cyclic GMP-dependent protein kinase in rat basal ganglia neurons

scientific article

Localization of focal adhesion kinase isoforms in cells of the central nervous system

scientific article

Long-lasting tagging of neurons activated by seizures or cocaine administration in Egr1-CreERT2 transgenic mice

scientific article published on 23 November 2020

Looking BAC at striatal signaling: cell-specific analysis in new transgenic mice.

scientific article published on 16 September 2009

MafA transcription factor is phosphorylated by p38 MAP kinase

scientific article published in July 2005

Mechanisms of locomotor sensitization to drugs of abuse in a two-injection protocol.

scientific article published on January 2010

Mitogen- and stress-activated protein kinase 1 is required for specific signaling responses in dopamine-denervated mouse striatum, but is not necessary for L-DOPA-induced dyskinesia

scientific article published on 16 September 2014

Modulation of the voltage-gated sodium current in rat striatal neurons by DARPP-32, an inhibitor of protein phosphatase

scientific article published in April 1998

Mouse Modeling Dissecting Macrophage-Breast Cancer Communication Uncovered Roles of PYK2 in Macrophage Recruitment and Breast Tumorigenesis

Neurofascin is a glial receptor for the paranodin/Caspr-contactin axonal complex at the axoglial junction

scientific article (publication date: 5 February 2002)

Nodal, paranodal and juxtaparanodal axonal proteins during demyelination and remyelination in multiple sclerosis

scientific article published on 9 June 2006

Nodes of ranvier and paranodes in chronic acquired neuropathies

scientific article

Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol

scientific article published in May 2008

Organization and post-transcriptional processing of focal adhesion kinase gene

scientific article published on 4 August 2006

PGY repeats and N-glycans govern the trafficking of paranodin and its selective association with contactin and neurofascin-155

scientific article published on 8 November 2006

PKA-dependent phosphorylation of ribosomal protein S6 does not correlate with translation efficiency in striatonigral and striatopallidal medium-sized spiny neurons

scientific article published in March 2015

PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions.

scientific article

PTK2B/Pyk2 overexpression improves a mouse model of Alzheimer's disease.

scientific article

Paranodin, a glycoprotein of neuronal paranodal membranes

scientific journal article

Parsing molecular and behavioral effects of cocaine in mitogen- and stress-activated protein kinase-1-deficient mice.

scientific article

Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease.

scientific article

Phosphorylation of DARPP-32 and protein phosphatase inhibitor-1 in rat choroid plexus: regulation by factors other than dopamine

scientific article published in August 1992

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

scientific article

Phosphorylation of DARPP-32, a Dopamine- and cAMP-regulated Phosphoprotein, by Casein Kinase Iin Vitroandin Vivo

scientific article published in Journal of Biological Chemistry

Phosphorylation of arfaptin 2 at Ser260 by Akt Inhibits PolyQ-huntingtin-induced toxicity by rescuing proteasome impairment

scientific article (publication date: 10 June 2005)

Plasticity-associated gene Krox24/Zif268 is required for long-lasting behavioral effects of cocaine.

scientific article

Plea for a Simple But Radical Change in Scientific Publication: To Improve Openness, Reliability, and Reproducibility, Let’s Deposit and Validate Our Results before Writing Articles

scientific article published in 2022

Protein 4.1B associates with both Caspr/paranodin and Caspr2 at paranodes and juxtaparanodes of myelinated fibres

scientific article (publication date: 2003)

Protein 4.1B contributes to the organization of peripheral myelinated axons

scientific article

Protein interaction mapping: a Drosophila case study

scientific article published on 14 February 2005

Protein phosphorylation and dephosphorylation in mammalian central nervous system.

scientific article

Protein phosphotyrosine in mouse brain: developmental changes and regulation by epidermal growth factor, type I insulin-like growth factor, and insulin

scientific article published on February 1992

Pyk2 Regulates MAMs and Mitochondrial Dynamics in Hippocampal Neurons

scientific article published on 01 March 2022

Pyk2 cytonuclear localization: mechanisms and regulation by serine dephosphorylation

scientific article

Pyk2 in the amygdala modulates chronic stress sequelae via PSD-95-related micro-structural changes

scientific article published on 15 January 2019

Pyk2 is essential for astrocytes mobility following brain lesion

scientific article published on 11 December 2015

Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model

scientific article published on 30 May 2017

Quantitative changes in Galphaolf protein levels, but not D1 receptor, alter specifically acute responses to psychostimulants

scientific article published on 25 October 2006

RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release

scientific article

Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum

scientific article

Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus.

scientific article published in March 2003

Release of newly synthesized 3H-dopamine in the striatum: an adaptation of the push-pull cannula method to awake restrained and anesthetized rats

scientific article published in February 1986

Requirement of pyk2 for the activation of the MAP kinase cascade induced by Ca(2+) (but not by PKC or G protein) in PC12 cells

scientific article published on 01 November 1999

Role of cannabinoid type 1 receptors in locomotor activity and striatal signaling in response to psychostimulants

scientific article published in June 2007

Role of the ERK pathway in psychostimulant-induced locomotor sensitization.

scientific article published on 2 March 2006

Role of the ERK/MSK1 signalling pathway in chromatin remodelling and brain responses to drugs of abuse.

scientific article published on 12 January 2009

Role of the plasticity-associated transcription factor zif268 in the early phase of instrumental learning

scientific article published on 23 January 2014

Rôle et régulation du récepteur D1 de la dopamine dans le striatum : implications dans les dyskinésies de la maladie de Parkinson

scientific article published on 01 June 2006

Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.

scientific article published on 15 December 2016

Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments.

scientific article

Selective Effects of PDE10A Inhibitors on Striatopallidal Neurons Require Phosphatase Inhibition by DARPP-32(1,2,3)

scientific article

Signaling in striatal neurons: the phosphoproteins of reward, addiction, and dyskinesia.

scientific article published on January 2012

Spatial distribution of D1R- and D2R-expressing medium-sized spiny neurons differs along the rostro-caudal axis of the mouse dorsal striatum

scientific article published on 29 July 2013

Specific interactions of neuronal focal adhesion kinase isoforms with Src kinases and amphiphysin

scientific article (publication date: 2003)

Stimulation of protein-tyrosine phosphorylation in rat striatum after lesion of dopamine neurons or chronic neuroleptic treatment

scientific article published on April 1992

Striatal medium-sized spiny neurons: identification by nuclear staining and study of neuronal subpopulations in BAC transgenic mice

scientific article

Striatal neurones have a specific ability to respond to phasic dopamine release

scientific article

Study of the conformation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by fluorescence spectroscopy

scientific article published in Journal of Biological Chemistry

Syndecan-3 and syndecan-4 are enriched in Schwann cell perinodal processes ⬇️

scientific article published on November 18, 2003

The DARPP-32/protein phosphatase-1 cascade: a model for signal integration

article

The ERK/MAP-kinases cascade in the nervous system.

scientific article

The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development.

scientific article

The neurobiology of dopamine signaling

scientific article

The paranodal complex of F3/contactin and caspr/paranodin traffics to the cell surface via a non-conventional pathway.

scientific article published on 12 September 2003

The role of DARPP-32 in the actions of drugs of abuse

scientific article published in January 2004

The translocation of focal adhesion kinase in brain synaptosomes is regulated by phosphorylation and actin assembly

scientific article

Transient and rapid activation of Akt/GSK-3β and mTORC1 signaling by D3 dopamine receptor stimulation in dorsal striatum and nucleus accumbens

scientific article published on 11 March 2013

Tumor Suppressor Schwannomin/Merlin Is Critical for the Organization of Schwann Cell Contacts in Peripheral Nerves

scientific article published on 01 October 2008

Two-photon Imaging of Microglial Processes' Attraction Toward ATP or Serotonin in Acute Brain Slices

scientific article published on 31 January 2019

Tyrosine phosphorylation of NMDA receptor in rat striatum: effects of 6-OH-dopamine lesions

scientific article published on 01 December 1995

Unilateral Lesion of Dopamine Neurons Induces Grooming Asymmetry in the Mouse

scientific article published on 23 September 2015

What is the degree of segregation between striatonigral and striatopallidal projections? ⬇️

scientific article published on October 7, 2010

[23] Production of phosphorylation state-specific antibodies

article

[Effect of lesions of the ventromedial nucleus of the thalamus on cerebral metabolism: experimental study in the rat using the 14C-deoxyglucose method]

scientific article published on 01 January 1986

[Paranodal junctions of myelinated fibers: site of anchorage and interactions]

scientific article published on 01 January 2003

cAMP and extracellular signal-regulated kinase signaling in response to d-amphetamine and methylphenidate in the prefrontal cortex in vivo: role of beta 1-adrenoceptors

scientific article published on 12 May 2005

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