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List of works by Jean-Philippe Pin

3-carboxy-4-phosphonocyclopentane amino acids: new metabotropic glutamate receptor ligands.

scientific article published on April 2003

35 mM K(+)-stimulated 45Ca2+ uptake in cerebellar granule cell cultures mainly results from NMDA receptor activation.

scientific article published in January 1993

A Cluster of Basic Residues in the Carboxyl-terminal Tail of the Short Metabotropic Glutamate Receptor 1 Variants Impairs Their Coupling to Phospholipase C

scientific article published on January 2, 1998

A critical pocket close to the glutamate binding site of mGlu receptors opens new possibilities for agonist design

scientific article published on 16 July 2010

A model for the functioning of family 3 GPCRs

scientific article published on 01 June 2002

A negative allosteric modulator modulates GABAB-receptor signalling through GB2 subunits.

scientific article

A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors.

scientific article published on 8 September 2010

A new family of receptor tyrosine kinases with a venus flytrap binding domain in insects and other invertebrates activated by aminoacids

scientific article

A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential

scientific article published on January 5, 2012

A novel site on the Galpha -protein that recognizes heptahelical receptors

scientific article published on 10 October 2000

A single olfactory receptor specifically binds a set of odorant molecules

scientific article published on 01 February 2002

A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor

scientific article

Activation of a dimeric metabotropic glutamate receptor by intersubunit rearrangement.

scientific article published on 13 September 2007

Agonist selectivity of mGluR1 and mGluR2 metabotropic receptors: a different environment but similar recognition of an extended glutamate conformation.

scientific article published on May 1999

Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer

scientific article (publication date: 21 June 2001)

Alleviating pain hypersensitivity through activation of type 4 metabotropic glutamate receptor.

scientific article published in November 2013

Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.

scientific article

Allosteric functioning of dimeric class C G-protein-coupled receptors.

scientific article

Allosteric interactions between GABAB1 subunits control orthosteric binding sites occupancy within GABAB oligomers.

scientific article published on 2 January 2018

Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function

scientific article

Allosteric modulation of metabotropic glutamate receptors by chloride ions

scientific article

Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state

scientific article published on 14 September 2021

Allosteric modulators of GABA(B) receptors: mechanism of action and therapeutic perspective.

scientific article published on September 2007

Allosteric modulators of group I metabotropic glutamate receptors: novel subtype-selective ligands and therapeutic perspectives.

scientific article

Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.

scientific article published on 6 December 2017

Amino-pyrrolidine tricarboxylic acids give new insight into group III metabotropic glutamate receptor activation mechanism

scientific article published on 13 December 2006

Aminobicyclo[2.2.1.]heptane dicarboxylic acids (ABHD), rigid analogs of ACPD and glutamic acid: synthesis and pharmacological activity on metabotropic receptors mGluR1 and mGluR2

scientific article published on 01 February 1998

Among the twenty classical L-amino acids, only glutamate directly activates metabotropic glutamate receptors.

scientific article published on 28 November 2005

An allosteric modulator to control endogenous G protein-coupled receptors with light.

scientific article published on 31 August 2014

An unusual receptor tyrosine kinase of Schistosoma mansoni contains a Venus Flytrap module.

scientific article

Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand.

scientific article published on 10 July 2017

Antibodies targeting G protein-coupled receptors: Recent advances and therapeutic challenges.

scientific article published on 5 May 2017

Asymmetric conformational changes in a GPCR dimer controlled by G-proteins.

scientific article published on 30 November 2006

Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.

scientific article

BAY36-7620: a potent non-competitive mGlu1 receptor antagonist with inverse agonist activity

scientific article

BRET and Time-resolved FRET strategy to study GPCR oligomerization: from cell lines toward native tissues.

scientific article

Biased signaling through G-protein-coupled PROKR2 receptors harboring missense mutations

scientific article published on 15 May 2014

Ca(2+) requirement for high-affinity gamma-aminobutyric acid (GABA) binding at GABA(B) receptors: involvement of serine 269 of the GABA(B)R1 subunit

scientific article

Cell surface detection of membrane protein interaction with homogeneous time-resolved fluorescence resonance energy transfer technology

scientific article published in June 2004

Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to G protein-coupled receptor oligomerization

scientific article published on January 1, 2011

Cerebellar granule cell survival and maturation induced by K+ and NMDA correlate with c-fos proto-oncogene expression

scientific article published on 01 December 1989

Changes in the carboxyl-terminal domain of metabotropic glutamate receptor 1 by alternative splicing generate receptors with differing agonist-independent activity.

scientific article

Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3

scientific article published on 11 August 2018

Cinnabarinic Acid, an Endogenous Metabolite of the Kynurenine Pathway, Activates Type 4 Metabotropic Glutamate Receptors

scientific article published on February 6, 2012

Class C G protein-coupled receptors: reviving old couples with new partners

scientific article published on 28 February 2017

Cloning and functional expression of a Drosophila metabotropic glutamate receptor expressed in the embryonic CNS.

scientific article published on November 1996

Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.

scientific article published on 4 July 2004

Common and selective molecular determinants involved in metabotopic glutamate receptor agonist activity

scientific article published in July 2002

Comparative effect of L-CCG-I, DCG-IV and gamma-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes.

scientific article published on August 1998

Complex GABAB receptor complexes: how to generate multiple functionally distinct units from a single receptor.

scientific article published on 11 February 2014

Conformational analysis of glutamic acid analogues as probes of glutamate receptors using molecular modelling and NMR methods. Comparison with specific agonists

scientific article published on 01 February 1997

Conservation of the ligand recognition site of metabotropic glutamate receptors during evolution.

scientific article

Correction: Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator

scientific article

Coupling of agonist binding to effector domain activation in metabotropic glutamate-like receptors

scientific article published on 20 June 2006

Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by homer1 proteins and neuronal excitation

scientific article published on 01 December 2000

Determination of the absolute configuration of phosphinic analogues of glutamate

scientific article published on 24 November 2014

Differential association modes of the thrombin receptor PAR1 with Galphai1, Galpha12, and beta-arrestin 1

scientific article published on 21 April 2010

Dimers and beyond: The functional puzzles of class C GPCRs.

scientific article published on 20 January 2011

Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs.

scientific article

Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling

scientific article published on September 17, 2012

Divergent evolution in metabotropic glutamate receptors. A new receptor activated by an endogenous ligand different from glutamate in insects.

scientific article published on December 2003

Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors.

scientific article published on January 1994

Dominant role of GABAB2 and Gbetagamma for GABAB receptor-mediated-ERK1/2/CREB pathway in cerebellar neurons.

scientific article

Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4.

scientific article published on 20 December 2016

Dynamics and modulation of metabotropic glutamate receptors.

scientific article published on 17 December 2014

Editorial overview: neurosciences: targeting glutamatergic signaling in CNS diseases: new hopes?

scientific article published on 15 January 2015

Effect of Glutamate and Ionomycin on the Release of Arachidonic Acid, Prostaglandins and HETEs from Cultured Neurons and Astrocytes

scientific article published on 01 January 1991

Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism.

scientific article

Exploring the Active Conformation of Cyclohexane Carboxylate Positive Allosteric Modulators of the Type 4 Metabotropic Glutamate Receptor

scientific article published on 05 September 2014

Extended glutamate activates metabotropic receptor types 1, 2 and 4: selective features at mGluR4 binding site

scientific article published on 01 October 1999

Extreme C Terminus of G Protein α-Subunits Contains a Site That Discriminates between Gi-coupled Metabotropic Glutamate Receptors

scientific article published on October 2, 1998

FRET-Based Sensors Unravel Activation and Allosteric Modulation of the GABAB Receptor

scientific article published on 6 March 2017

Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy

scientific article published in Nature Communications

First enantiospecific synthesis of a 3,4-dihydroxy-L-glutamic acid [(3S,4S)-DHGA], a new mGluR1 agonist.

scientific article

Fluorescent ligands to investigate GPCR binding properties and oligomerization.

scientific article

From the Promiscuous Asenapine to Potent Fluorescent Ligands Acting at a Series of Aminergic G-Protein-Coupled Receptors

scientific article published on 8 December 2017

Functioning of the dimeric GABA(B) receptor extracellular domain revealed by glycan wedge scanning.

scientific article published on 3 April 2008

G Protein-Coupled Receptor Multimers: A Question Still Open Despite the Use of Novel Approaches

scientific article

G protein activation by the leukotriene B4 receptor dimer. Evidence for an absence of trans-activation.

scientific article

G protein-coupled receptor oligomerization revisited: functional and pharmacological perspectives

scientific article published on 10 February 2014

G-protein-coupled receptor oligomers: two or more for what? Lessons from mGlu and GABAB receptors.

scientific article published on September 2009

GABAB receptor activation protects neurons from apoptosis via IGF-1 receptor transactivation.

scientific article published in January 2010

GABAB receptor promotes its own surface expression by recruiting a Rap1-dependent signaling cascade.

scientific article published on 12 May 2015

GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base.

scientific article

Generic GPCR residue numbers - aligning topology maps while minding the gaps

scientific article

Get receptive to metabotropic glutamate receptors

scientific article published on June 1, 1995

Group III and subtype 4 metabotropic glutamate receptor agonists: Discovery and pathophysiological applications in Parkinson's disease

scientific article published on June 1, 2012

Group III metabotropic glutamate receptors inhibit hyperalgesia in animal models of inflammation and neuropathic pain.

scientific article

HTRF® Total and Phospho-YAP (Ser127) Cellular Assays

scientific article published on 01 January 2019

HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.

scientific article published on 30 January 2017

Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.

scholarly article

Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons.

scientific article published in June 2002

Homogeneous time-resolved fluorescence-based assay to monitor extracellular signal-regulated kinase signaling in a high-throughput format

scientific article published on 23 June 2014

IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels

scientific article

Identification of key phosphorylation sites in PTH1R that determine arrestin3 binding and fine-tune receptor signaling

scientific article

Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals

scientific article published on 19 December 2016

Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors

scientific article published on 4 March 2013

Illuminating the allosteric modulation of the calcium-sensing receptor

scientific article published on 19 August 2020

Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites.

scientific article published on 4 February 2018

Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice.

scientific article published on 12 March 2018

Integrated synthetic, pharmacological, and computational investigation of cis-2-(3,5-dichlorophenylcarbamoyl)cyclohexanecarboxylic acid enantiomers as positive allosteric modulators of metabotropic glutamate receptor subtype 4.

scientific article published on January 2011

Interaction of Protease-Activated Receptor 2 with G Proteins and β-Arrestin 1 Studied by Bioluminescence Resonance Energy Transfer

scientific article published on 20 December 2013

Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses.

scientific article published on 15 February 2007

Interdomain movements in metabotropic glutamate receptor activation

scientific article published on September 6, 2011

International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers.

scientific article published on March 2007

International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands.

scientific article

International Union of Pharmacology. LVI. Ghrelin receptor nomenclature, distribution, and function

scientific article

International Union of Pharmacology. XLVI. G protein-coupled receptor list.

scientific article

Intracellular messengers associated with excitatory amino acid (EAA) receptors.

scientific article published on January 1990

Introduction to the special issue on High Resolution Neuropharmacology

scientific article published on 04 September 2010

Investigation of prolactin receptor activation and blockade using time-resolved fluorescence resonance energy transfer

scientific article

L-(+)-2-Amino-4-thiophosphonobutyric acid (L-thioAP4), a new potent agonist of group III metabotropic glutamate receptors: increased distal acidity affords enhanced potency.

scientific article published on 28 August 2007

Le site de référence du Partenariat européen d’innovation pour un vieillissement actif et en bonne santé MACVIA-LR (contre les maladies chroniques pour un vieillissement en bonne santé en Languedoc-Roussillon)

scientific article published in November 2015

Locking the dimeric GABA(B) G-protein-coupled receptor in its active state.

scientific article published on January 2004

Long-term expression of the c-fos protein during the in vitro differentiation of cerebellar granule cells induced by potassium or NMDA.

scientific article published in January 1992

Maitotoxin-evoked gamma-aminobutyric acid release is due not only to the opening of calcium channels.

scientific article published in April 1988

Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer.

scientific article published on 15 December 2014

Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors

scientific article published on 01 December 2000

Measurement of gamma-enolase release, a new method for selective quantification of neurotoxicity independently from glial lysis

scientific article published on October 9, 1992

Metabotropic glutamate receptors: from the workbench to the bedside

scientific article published on October 29, 2010

Metabotropic receptors for glutamate and GABA in pain.

scientific article published on 25 December 2008

Modeling the binding and function of metabotropic glutamate receptors.

scientific article published on 20 February 2008

Molecular determinants involved in the allosteric control of agonist affinity in the GABAB receptor by the GABAB2 subunit.

scientific article published on 21 January 2004

Molecular mechanisms of GABA(B) receptor activation: new insights from the mechanism of action of CGP7930, a positive allosteric modulator.

scientific article published in November 2004

Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1.

scientific article published on May 1995

Multicolor time-resolved Förster resonance energy transfer microscopy reveals the impact of GPCR oligomerization on internalization processes

scientific article published on 17 February 2015

Multiple Cl(-)-independent binding sites for the excitatory amino acids: glutamate, aspartate and cysteine sulfinate in rat brain membranes

scientific article published on 01 January 1987

NMDA receptor activation stimulates phospholipase A2 and somatostatin release from rat cortical neurons in primary cultures

scientific article published on March 12, 1992

New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III.

scientific article

New perspectives for the development of selective metabotropic glutamate receptor ligands.

scientific article

No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.

scientific article published on September 2002

Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics.

scientific article published on 10 July 2018

Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator

scientific article published on 11 April 2017

OptoGluNAM4.1, a Photoswitchable Allosteric Antagonist for Real-Time Control of mGlu4 Receptor Activity.

scientific article published on 27 July 2016

Organization and functions of mGlu and GABAB receptor complexes

scientific article published on December 2016

Original Fluorescent Ligand-Based Assays Open New Perspectives in G-Protein Coupled Receptor Drug Screening.

scientific article

Overlapping binding sites drive allosteric agonism and positive cooperativity in type 4 metabotropic glutamate receptors

scientific article published on 23 October 2014

PROKR2 missense mutations associated with Kallmann syndrome impair receptor signalling activity

scientific article

Pharmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures.

scientific article

Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells

scientific article

Pharmacology and functions of metabotropic glutamate receptors

scientific article (publication date: 1997)

Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses

scientific article published on 01 August 1995

Phospholipase A and Somatostatin Release are Activated in Response to N-Methyl-D-Aspartate Receptor Stimulation in Hypothalamic Neurons in Primary Culture.

scientific article

Physiological and pharmacological profile oftrans-azetidine-2,4-dicarboxylic acid: Metabotropic glutamate receptor agonism and effects on long-term potentiation

scientific article published in June 1996

Plasticity of NMDA receptor expression during mouse cerebellar granule cell development.

scientific article published in October 1994

Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5 negative allosteric modulation.

scientific article published on 12 January 2017

Positive Allosteric Modulators for γ-Aminobutyric AcidBReceptors Open New Routes for the Development of Drugs Targeting Family 3 G-Protein-Coupled Receptors

scientific article published on November 1, 2001

Probing the existence of G protein-coupled receptor dimers by positive and negative ligand-dependent cooperative binding.

scientific article published on 22 August 2006

Rat group I metabotropic glutamate receptors inhibit neuronal Ca2+ channels via multiple signal transduction pathways in HEK 293 cells.

scientific article published in January 1998

Real-time analysis of agonist-induced activation of protease-activated receptor 1/Galphai1 protein complex measured by bioluminescence resonance energy transfer in living cells

scientific article

Rearrangement of the transmembrane domain interfaces associated with the activation of a GPCR hetero-oligomer

scientific article published on 24 June 2019

Receptor-G protein interaction studied by bioluminescence resonance energy transfer: lessons from protease-activated receptor 1.

scientific article published on 22 June 2012

Release of endogenous amino acids from striatal neurons in primary culture.

scientific article published on August 1986

RgIA4 Potently Blocks Mouse α9α10 nAChRs and Provides Long Lasting Protection against Oxaliplatin-Induced Cold Allodynia.

scientific article

Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.

scientific article

Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective

scientific article published on 7 April 2015

Stability of GABAB receptor oligomers revealed by dual TR-FRET and drug-induced cell surface targeting.

scientific article published on 21 May 2012

Structural basis of the activation of a metabotropic GABA receptor

scientific article published on 17 June 2020

Structure and functional interaction of the extracellular domain of human GABAB receptor GBR2

scientific article

Surface expression of metabotropic glutamate receptor variants mGluR1a and mGluR1b in transfected HEK293 cells.

scientific article

Synthesis and Pharmacological Characterization of Aminocyclopentanetricarboxylic Acids: New Tools to Discriminate between Metabotropic Glutamate Receptor Subtypes

scientific article published on September 12, 1997

Synthesis and studies on the mGluR agonist activity of FAP4 stereoisomers.

scientific article published on 22 April 2015

The C terminus of the metabotropic glutamate receptor subtypes 2 and 7 specifies the receptor signaling pathways

scientific journal article

The C-terminal domain of the mGluR1 metabotropic glutamate receptor affects sensitivity to agonists.

scientific article published on July 1996

The Ca2+/C1- dependent L-[3H]glutamate binding: a new receptor or a particular transport process?

scientific article published in September 1984

The Concise Guide to PHARMACOLOGY 2013/14: overview

scientific article

The G Protein-Coupling Profile of Metabotropic Glutamate Receptors, as Determined with Exogenous G Proteins, Is Independent of Their Ligand Recognition Domain

scientific article published on April 1, 1998

The N-terminal domain of gamma-aminobutyric Acid(B) receptors is sufficient to specify agonist and antagonist binding.

scientific article published on August 1999

The asymmetric/symmetric activation of GPCR dimers as a possible mechanistic rationale for multiple signalling pathways.

scientific article published on 04 December 2009

The chemokine CXC4 and CC2 receptors form homo- and heterooligomers that can engage their signaling G-protein effectors and βarrestin.

scientific article

The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor

scientific article

The metabotropic glutamate receptor mGluR5 is endocytosed by a clathrin-independent pathway.

scientific article published on 15 January 2003

The metabotropic glutamate receptors: structure and functions

scientific journal article

The metabotropic glutamate receptors: structure, activation mechanism and pharmacology

scientific article (publication date: June 2002)

The metabotropic glutamate receptors: their second intracellular loop plays a critical role in the G-protein coupling specificity.

scientific article

The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate recepto

scientific article published on 01 October 2000

The oligomeric state sets GABA(B) receptor signalling efficacy

scientific journal article

The presence of non-neuronal cells influences somatostatin release from cultured cerebral cortical cells

scientific article published on 01 May 1988

The rat mGlu1d receptor splice variant shares functional properties with the other short isoforms of mGlu1 receptor.

scientific article

The second intracellular loop of metabotropic glutamate receptor 1 cooperates with the other intracellular domains to control coupling to G-proteins.

scientific article published in January 1996

The second intracellular loop of metabotropic glutamate receptors recognizes C termini of G-protein alpha-subunits.

scientific article

Time resolved FRET strategy with fluorescent ligands to analyze receptor interactions in native tissues: application to GPCR oligomerization.

scientific article published in January 2011

Time-resolved FRET between GPCR ligands reveals oligomers in native tissues.

scientific article

Time-resolved FRET binding assay to investigate hetero-oligomer binding properties: proof of concept with dopamine D1/D3 heterodimer.

scientific article published on 11 November 2014

Time-resolved FRET strategy to screen GPCR ligand library

scientific article published on January 2015

Trans-activation between 7TM domains: implication in heterodimeric GABABreceptor activation

scientific article published on November 9, 2010

Tuning synaptic activity with light-controlled GPCRs

scientific article published on 01 April 2013

Two distinct mechanisms, differentially affected by excitatory amino acids, trigger GABA release from fetal mouse striatal neurons in primary culture

scientific article published in February 1989

Untangling dopamine-adenosine receptor-receptor assembly in experimental parkinsonism in rats

scientific article

Virtual screening workflow development guided by the "receiver operating characteristic" curve approach. Application to high-throughput docking on metabotropic glutamate receptor subtype 4

scientific article published on 01 April 2005

[G-protein-coupled receptors dimers and oligomers: for which purpose? The GABA(B) receptor under investigation]

scientific article published on 12 October 2012

[Use of a G-protein-coupled receptor to communicate. An evolutionary success]

scientific article published on 01 July 1998

mGluR7-like metabotropic glutamate receptors inhibit NMDA-mediated excitotoxicity in cultured mouse cerebellar granule neurons.

scientific article published in February 1999

mGluR7-like receptor and GABA(B) receptor activation enhance neurotoxic effects of N-methyl-D-aspartate in cultured mouse striatal GABAergic neurones.

scientific article

α-Amino-β-fluorocyclopropanecarboxylic acids as a new tool for drug development: Synthesis of glutamic acid analogs and agonist activity towards metabotropic glutamate receptor 4

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