List of works - Paul J Norman

16(th) IHIW : review of HLA typing by NGS.

scientific article published on February 2013

A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia

scientific article

A comparison of HLA-DR and -DQ allele and haplotype frequencies in Trinidadian populations of African, South Asian, and mixed ancestry

scientific article

A multi-laboratory characterization of the KIR genotypes of 10th International Histocompatibility Workshop cell lines.

scientific article published on May 2003

A specific amino acid motif of mediates risk and interacts with smoking history in Parkinson's disease

scientific article published on 25 March 2019

A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44

scientific article published on 29 July 2019

Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1

scientific article published on 22 February 2022

Allele-Level Genotyping of More Than a Million Samples: Workflow, Algorithm, and Observations

scientific article published on 04 December 2018

Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires

scientific article (publication date: February 2011)

Analysis of Fc gamma receptor II (CD32) polymorphism in populations of African and South Asian ancestry reveals east-west geographic gradients of allele frequencies

article

Analysis of Genomic DNA from Medieval Plague Victims Suggests Long-Term Effect of Yersinia pestis on Human Immunity Genes

scientific article published on 01 September 2021

Bonobos Maintain Immune System Diversity with Three Functional Types of MHC-B.

scientific article published on 27 March 2017

Chimpanzee susceptibility to hepatitis C virus infection correlates with presence of Pt-KIR3DS2 and Pt-KIR2DL9: paired activating and inhibitory natural killer cell receptors

scientific article

Chimpanzees use more varied receptors and ligands than humans for inhibitory killer cell Ig-like receptor recognition of the MHC-C1 and MHC-C2 epitopes

scientific article

Class I HLA haplotypes form two schools that educate NK cells in different ways

scientific article published on 09 September 2016

Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

scientific article (publication date: October 2013)

Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands

scientific article published on 16 October 2009

Co-evolution of MHC class I and variable NK cell receptors in placental mammals

scientific article published on September 2015

Complex interactions: the immunogenetics of human leukocyte antigen and killer cell immunoglobulin-like receptors

scientific article

Conservation, Extensive Heterozygosity, and Convergence of Signaling Potential All Indicate a Critical Role for KIR3DL3 in Higher Primates

scientific article published on 28 January 2019

Cost-effective and fast KIR gene-content genotyping by multiplex melting curve analysis

scientific article published on 01 December 2018

DNA sequence variation and molecular genotyping of natural killer leukocyte immunoglobulin-like receptor, LILRA3.

scientific article

Deciphering the killer-cell immunoglobulin-like receptor system at super-resolution for natural killer and T-cell biology

scientific article published on 25 October 2016

Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing.

scientific article published on August 2016

Definition of the cattle killer cell Ig-like receptor gene family: comparison with aurochs and human counterparts

scientific article

Description of the novelKIR2DL4*035allele identified using high-throughput sequencing

scientific article published on 24 February 2016

Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2+ HLA-C in Two Indigenous Human Populations in Southern Africa.

scientific article published on 16 March 2018

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus

scientific article (publication date: 29 December 2010)

Dimorphic motifs in D0 and D1+D2 domains of killer cell Ig-like receptor 3DL1 combine to form receptors with high, moderate, and no avidity for the complex of a peptide derived from HIV and HLA-A*2402.

scientific article

Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles

scientific article published on 26 June 2017

Distribution of natural killer cell immunoglobulin-like receptor sequences in three ethnic groups

scientific article published on 01 January 2001

Diversity of KIR, HLA Class I, and Their Interactions in Seven Populations of Sub-Saharan Africans

scientific article published on 27 March 2019

Exome capture from saliva produces high quality genomic and metagenomic data

scientific article

Fluctuating and Geographically Specific Selection Characterize Rapid Evolution of the Human KIR Region.

scientific article

Genetic analyses of diverse populations improves discovery for complex traits

scientific article published on 19 June 2019

Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry

scientific article published on October 2013

Genetic determinism in the relationship between human CD4 + and CD8 + T lymphocyte populations?

article

Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism.

scientific article published on 4 June 2019

Genomic evidence for the Pleistocene and recent population history of Native Americans

scientific article

HLA class I variation in Iranian Lur and Kurd populations: high haplotype and allotype diversity with an abundance of KIR ligands.

scientific article published on 24 August 2016

Hematopoietic stem cell transplantation: Improving alloreactive Bw4 donor selection by genotyping codon 86 of KIR3DL1/S1.

scientific article published on 18 March 2016

High KIR diversity in Amerindians is maintained using few gene-content haplotypes

article

High-Resolution Characterization of <i>KIR</i> Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity

scientific article published on 07 May 2021

High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia

scientific article published on 24 September 2018

Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage

scientific article published on 20 December 2017

Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules

scientific article published on March 2012

Hunter-gatherer genomic diversity suggests a southern African origin for modern humans

scientific article

In vitro education of human natural killer cells by KIR3DL1

scientific article published on 13 November 2019

Isolation, purification and flow cytometric analysis of human intrahepatic lymphocytes using an improved technique

scientific article

KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors

scientific article published on 02 April 2020

KIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand.

scientific article

KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A * 11 while diminishing avidity for HLA-C

scientific article

KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans

scientific article published on 6 July 2017

KIR3DL1/S1 Allotypes Contribute Differentially to the Development of Behçet Disease

scientific article published on 12 August 2019

Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson Disease

scientific article published on 24 July 2020

Killer Ig-like receptor (KIR) genotype predicts the capacity of human KIR-positive CD56dim NK cells to respond to pathogen-associated signals

scientific article

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population

scientific article published on 20 August 2015

Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.

scientific article (publication date: May 2009)

Minimum information for reporting next generation sequence genotyping (MIRING): Guidelines for reporting HLA and KIR genotyping via next generation sequencing

scientific article

Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3.

scientific article

Natural Killer Cells Offer Differential Protection From Leukemia in Chinese Southern Han

scientific article published on 16 July 2019

Natural killer cell immunoglobulin-like receptor (KIR) locus profiles in African and South Asian populations

scientific article

Natural killer-cell activity after human renal transplantation in relation to killer immunoglobulin-like receptors and human leukocyte antigen mismatch1

scientific article published on 01 October 2003

Natural selection on marine carnivores elaborated a diverse family of classical MHC class I genes exhibiting haplotypic gene content variation and allelic polymorphism

scientific article

Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes

scientific article

Polymorphic sites away from the Bw4 epitope that affect interaction of Bw4+ HLA-B with KIR3DL1

scientific article

Primate-specific regulation of natural killer cells.

scientific article

Quantitative trait loci on chromosomes 1, 2, 3, 4, 8, 9, 11, 12, and 18 control variation in levels of T and B lymphocyte subpopulations

scientific article published on 9 April 2002

Race, Ethnicity and Ancestry in Unrelated Transplant Matching for the National Marrow Donor Program: A Comparison of Multiple Forms of Self-Identification with Genetics.

scientific article published on 19 August 2015

Reconstructing the population genetic history of the Caribbean.

scientific article

Reduced telomere length in rheumatoid arthritis is independent of disease activity and duration

scientific article published on 17 November 2006

Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation

scientific article published on 28 September 2015

Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17 International HLA and Immunogenetics Workshop

scientific article published on 12 October 2018

Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C.

scientific article

Review: Immunogenetics of human placentation

scientific article published on 15 December 2011

Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.

scientific article published on 30 March 2017

Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz

scientific article (publication date: May 2015)

The Combinatorial Diversity of KIR and HLA class I Allotypes in Peninsular Malaysia

scientific article published on 06 December 2020

The production of KIR-Fc fusion proteins and their use in a multiplex HLA class I binding assay

scientific article

The shaping of modern human immune systems by multiregional admixture with archaic humans

scientific article

Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes.

scientific article published on 6 March 2017

Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and γδ T cells.

scientific article published on 3 May 2017

Unusual selection on the KIR3DL1/S1 natural killer cell receptor in africans

scientific article published on 12 August 2007

Variable NK cell receptors exemplified by human KIR3DL1/S1

scientific article published on July 2011

Very long haplotype tracts characterized at high resolution from HLA homozygous cell lines

scientific article

List of works by Paul J Norman

16(th) IHIW : review of HLA typing by NGS.

A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia

A comparison of HLA-DR and -DQ allele and haplotype frequencies in Trinidadian populations of African, South Asian, and mixed ancestry

A multi-laboratory characterization of the KIR genotypes of 10th International Histocompatibility Workshop cell lines.

A specific amino acid motif of mediates risk and interacts with smoking history in Parkinson's disease

A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44

Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1

Allele-Level Genotyping of More Than a Million Samples: Workflow, Algorithm, and Observations

Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires

Analysis of Fc gamma receptor II (CD32) polymorphism in populations of African and South Asian ancestry reveals east-west geographic gradients of allele frequencies

Analysis of Genomic DNA from Medieval Plague Victims Suggests Long-Term Effect of Yersinia pestis on Human Immunity Genes

Bonobos Maintain Immune System Diversity with Three Functional Types of MHC-B.

Chimpanzee susceptibility to hepatitis C virus infection correlates with presence of Pt-KIR3DS2 and Pt-KIR2DL9: paired activating and inhibitory natural killer cell receptors

Chimpanzees use more varied receptors and ligands than humans for inhibitory killer cell Ig-like receptor recognition of the MHC-C1 and MHC-C2 epitopes

Class I HLA haplotypes form two schools that educate NK cells in different ways

Co-evolution of Human Leukocyte Antigen (HLA) Class I Ligands with Killer-Cell Immunoglobulin-Like Receptors (KIR) in a Genetically Diverse Population of Sub-Saharan Africans

Co-evolution of KIR2DL3 with HLA-C in a human population retaining minimal essential diversity of KIR and HLA class I ligands

Co-evolution of MHC class I and variable NK cell receptors in placental mammals

Complex interactions: the immunogenetics of human leukocyte antigen and killer cell immunoglobulin-like receptors

Conservation, Extensive Heterozygosity, and Convergence of Signaling Potential All Indicate a Critical Role for KIR3DL3 in Higher Primates

Cost-effective and fast KIR gene-content genotyping by multiplex melting curve analysis

DNA sequence variation and molecular genotyping of natural killer leukocyte immunoglobulin-like receptor, LILRA3.

Deciphering the killer-cell immunoglobulin-like receptor system at super-resolution for natural killer and T-cell biology

Defining KIR and HLA Class I Genotypes at Highest Resolution via High-Throughput Sequencing.

Definition of the cattle killer cell Ig-like receptor gene family: comparison with aurochs and human counterparts

Description of the novelKIR2DL4*035allele identified using high-throughput sequencing

Different Selected Mechanisms Attenuated the Inhibitory Interaction of KIR2DL1 with C2+ HLA-C in Two Indigenous Human Populations in Southern Africa.

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus

Dimorphic motifs in D0 and D1+D2 domains of killer cell Ig-like receptor 3DL1 combine to form receptors with high, moderate, and no avidity for the complex of a peptide derived from HIV and HLA-A*2402.

Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles

Distribution of natural killer cell immunoglobulin-like receptor sequences in three ethnic groups

Diversity of KIR, HLA Class I, and Their Interactions in Seven Populations of Sub-Saharan Africans

Exome capture from saliva produces high quality genomic and metagenomic data

Fluctuating and Geographically Specific Selection Characterize Rapid Evolution of the Human KIR Region.

Genetic analyses of diverse populations improves discovery for complex traits

Genetic and environmental determinants of human NK cell diversity revealed by mass cytometry

Genetic determinism in the relationship between human CD4 + and CD8 + T lymphocyte populations?

Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism.

Genomic evidence for the Pleistocene and recent population history of Native Americans

HLA class I variation in Iranian Lur and Kurd populations: high haplotype and allotype diversity with an abundance of KIR ligands.

Hematopoietic stem cell transplantation: Improving alloreactive Bw4 donor selection by genotyping codon 86 of KIR3DL1/S1.

High KIR diversity in Amerindians is maintained using few gene-content haplotypes

High-Resolution Characterization of <i>KIR</i> Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity

High-Resolution Genetic and Phenotypic Analysis of KIR2DL1 Alleles and Their Association with Pre-Eclampsia

Human NK Cells Downregulate Zap70 and Syk in Response to Prolonged Activation or DNA Damage

Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules

Hunter-gatherer genomic diversity suggests a southern African origin for modern humans

In vitro education of human natural killer cells by KIR3DL1

Isolation, purification and flow cytometric analysis of human intrahepatic lymphocytes using an improved technique

KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors

KIR diversity in Māori and Polynesians: populations in which HLA-B is not a significant KIR ligand.

KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A * 11 while diminishing avidity for HLA-C

KIR2DS5 allotypes that recognize the C2 epitope of HLA-C are common among Africans and absent from Europeans

KIR3DL1/S1 Allotypes Contribute Differentially to the Development of Behçet Disease

Killer Cell Immunoglobulin-like Receptor Variants Are Associated with Protection from Symptoms Associated with More Severe Course in Parkinson Disease

Killer Ig-like receptor (KIR) genotype predicts the capacity of human KIR-positive CD56dim NK cells to respond to pathogen-associated signals

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population

Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.

Minimum information for reporting next generation sequence genotyping (MIRING): Guidelines for reporting HLA and KIR genotyping via next generation sequencing

Mutation at positively selected positions in the binding site for HLA-C shows that KIR2DL1 is a more refined but less adaptable NK cell receptor than KIR2DL3.

Natural Killer Cells Offer Differential Protection From Leukemia in Chinese Southern Han

Natural killer cell immunoglobulin-like receptor (KIR) locus profiles in African and South Asian populations

Natural killer-cell activity after human renal transplantation in relation to killer immunoglobulin-like receptors and human leukocyte antigen mismatch1

Natural selection on marine carnivores elaborated a diverse family of classical MHC class I genes exhibiting haplotypic gene content variation and allelic polymorphism

Polymorphic HLA-C Receptors Balance the Functional Characteristics of KIR Haplotypes

Polymorphic sites away from the Bw4 epitope that affect interaction of Bw4+ HLA-B with KIR3DL1

Primate-specific regulation of natural killer cells.

Quantitative trait loci on chromosomes 1, 2, 3, 4, 8, 9, 11, 12, and 18 control variation in levels of T and B lymphocyte subpopulations

Race, Ethnicity and Ancestry in Unrelated Transplant Matching for the National Marrow Donor Program: A Comparison of Multiple Forms of Self-Identification with Genetics.

Reconstructing the population genetic history of the Caribbean.

Reduced telomere length in rheumatoid arthritis is independent of disease activity and duration

Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation

Report from the Killer-cell Immunoglobulin-like Receptors (KIR) component of the 17 International HLA and Immunogenetics Workshop

Resurrecting KIR2DP1: A Key Intermediate in the Evolution of Human Inhibitory NK Cell Receptors That Recognize HLA-C.

Review: Immunogenetics of human placentation

Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.

Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz

The Combinatorial Diversity of KIR and HLA class I Allotypes in Peninsular Malaysia

The production of KIR-Fc fusion proteins and their use in a multiplex HLA class I binding assay