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List of works by George M. Church

3D mapping and accelerated super-resolution imaging of the human genome using in situ sequencing

scientific article published on 27 July 2020

A BioBrick compatible strategy for genetic modification of plants

scientific article published on 20 June 2012

A CRISPR-Cas9-based gene drive platform for genetic interaction analysis in Candida albicans.

scientific article published on 23 October 2017

A Call For a Three-tiered Pandemic Public Health Strategy in Context of SARS-CoV-2

scientific article published on 16 June 2020

A Deep Learning Approach to Antibiotic Discovery

scientific article published on 01 February 2020

A National Network of Neurotechnology Centers for the BRAIN Initiative

scientific article published on 14 October 2015

A bacterial strain with a unique quadruplet codon specifying non-native amino acids

scientific article

A comprehensive library of human transcription factors for cell fate engineering

scientific article published on 30 November 2020

A computational analysis of whole-genome expression data reveals chromosomal domains of gene expression

scientific article

A deep learning approach to programmable RNA switches

scientific article published on 07 October 2020

A dynamic programming approach to de novo peptide sequencing via tandem mass spectrometry.

scientific article published in January 2001

A functional metagenomic approach for expanding the synthetic biology toolbox for biomass conversion

scientific article (publication date: 13 April 2010)

A general strategy to construct small molecule biosensors in eukaryotes

scientific article published on 29 December 2015

A haplotype-aware de novo assembly of related individuals using pedigree sequence graph

scientific article published on 20 December 2019

A highly annotated whole-genome sequence of a Korean individual

scientific article

A logic-gated nanorobot for targeted transport of molecular payloads

scientific article

A machine learning toolkit for genetic engineering attribution to facilitate biosecurity

scientific article published on 08 December 2020

A microarray-based antibiotic screen identifies a regulatory role for supercoiling in the osmotic stress response of Escherichia coli

scientific article

A motif co-occurrence approach for genome-wide prediction of transcription-factor-binding sites in Escherichia coli

scientific article published on February 2004

A multifunctional AAV-CRISPR-Cas9 and its host response

scientific article published on 05 September 2016

A network of transcriptionally coordinated functional modules in Saccharomyces cerevisiae

scientific article published on 18 August 2005

A new dawn for industrial photosynthesis

scientific article (publication date: March 2011)

A public resource facilitating clinical use of genomes

scientific article (publication date: 24 July 2012)

A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells

scientific article

A robust benchmark for detection of germline large deletions and insertions

scientific article published on 15 June 2020

A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies

scientific article published in July 2006

A single combination gene therapy treats multiple age-related diseases

scientific article published on 04 November 2019

A survey of genomic traces reveals a common sequencing error, RNA editing, and DNA editing

scientific article

A systematic comparison of error correction enzymes by next-generation sequencing

scientific article published on September 2017

A whole genome approach to in vivo DNA-protein interactions in E. coli

scientific article published on December 10, 1992

Accurate Whole Genome Sequencing as the Ultimate Genetic Test

scientific article published on 05 December 2014

Accurate multiplex gene synthesis from programmable DNA microchips

scientific article

Accurate multiplex polony sequencing of an evolved bacterial genome

scientific article

Accurate whole-genome sequencing and haplotyping from 10 to 20 human cells.

scientific article

Adaptive evolution of genomically recoded Escherichia coli.

scientific article published on 13 February 2018

Addressing the ethical issues raised by synthetic human entities with embryo-like features

scientific article published on 21 March 2017

Advanced sequencing technologies: methods and goals

scientific article

Advancing the search for extra-terrestrial genomes

Algorithms for Identifying Protein Cross-Links via Tandem Mass Spectrometry ⬇️

scientific article published on January 1, 2001

Algorithms for the selection of fluorescent reporters

scientific article published on 16 May 2020

An analysis and validation pipeline for large-scale RNAi-based screens.

scientific article published on 16 January 2013

An enhanced CRISPR repressor for targeted mammalian gene regulation

scientific article published on 16 July 2018

An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes

scientific article

An integrated strategy for analyzing the unique developmental programs of different myoblast subtypes

scientific article

An open-source oligomicroarray standard for human and mouse

scientific article published on 01 November 2002

An unbiased index to quantify participant's phenotypic contribution to an open-access cohort

scientific article

Analyses of human-chimpanzee orthologous gene pairs to explore evolutionary hypotheses of aging

scientific article published on 25 March 2007

Analysis of optimality in natural and perturbed metabolic networks

scientific article

Applications of Engineered Synthetic Ecosystems

article

Assaying chromosomal inversions by single-molecule haplotyping

scientific article published on June 2006

Assessing computational tools for the discovery of transcription factor binding sites

scientific article

Author Correction: A robust benchmark for detection of germline large deletions and insertions

scientific article published on 22 July 2020

Author Correction: Data privacy in the age of personal genomics

scientific article published on 01 November 2019

Autoantigen discovery with a synthetic human peptidome

scientific article

Automated electrotransformation of Escherichia coli on a digital microfluidic platform using bioactivated magnetic beads

scientific article

Automated modelling of signal transduction networks

scientific article

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

scientific article

BIOSAFETY. Safeguarding gene drive experiments in the laboratory

scientific article

Back to the future: from genome to metabolome

scientific article published on May 2012

Bacteria subsisting on antibiotics

scientific article published in April 2008

Barcoding bias in high-throughput multiplex sequencing of miRNA.

scientific article

Barcoding cells using cell-surface programmable DNA-binding domains

scientific article published on 17 March 2013

Benchmarking evolutionary tinkering underlying human-viral molecular mimicry shows multiple host pulmonary-arterial peptides mimicked by SARS-CoV-2

scientific article published on 02 October 2020

Beyond editing to writing large genomes

scientific article published on 30 August 2017

Bioart

scientific article

Biocontainment of genetically modified organisms by synthetic protein design

scientific article

Biosensor libraries harness large classes of binding domains for construction of allosteric transcriptional regulators

scientific article published in Nature Communications

Biosensor-based engineering of biosynthetic pathways

scientific article

Biotechnology. A prudent path forward for genomic engineering and germline gene modification

scientific article

Biotechnology. Regulating gene drives

scientific article

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering ⬇️

scientific article (publication date: September 2013)

CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing

scientific article

CRISPR-Cas-mediated targeted genome editing in human cells

scientific article published in January 2014

CRISPR-Cas9 System: Opportunities and Concerns

scientific article published on 22 August 2016

CRISPR/Cas9-Directed Genome Editing of Cultured Cells

scientific article published on July 2014

CRISPR/Cas9-mediated phage resistance is not impeded by the DNA modifications of phage T4

scientific article

CRISPR–Cas encoding of a digital movie into the genomes of a population of living bacteria

scientific article

Cas9 as a versatile tool for engineering biology

scientific article

Cas9 gRNA engineering for genome editing, activation and repression.

scientific article

Causes and effects of N-terminal codon bias in bacterial genes

scientific article

Cells discover fire: employing reactive oxygen species in development and consequences for aging.

scientific article

Characterization of Cas9-Guide RNA Orthologs

scientific article published on 2 May 2016

Characterizing Cas9 Protospacer-Adjacent Motifs with High-Throughput Sequencing of Library Depletion Experiments

scientific article

Characterizing the portability of phage-encoded homologous recombination proteins

scientific article published on 18 January 2021

Chromosomal periodicity of evolutionarily conserved gene pairs

scholarly article

Chromosome-scale, haplotype-resolved assembly of human genomes

scientific article published on 07 December 2020

Clinical assessment incorporating a personal genome

scientific article

Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes

scientific article

Codon usage of highly expressed genes affects proteome-wide translation efficiency

scientific article published on 07 May 2018

Cogenerating Synthetic Parts toward a Self-Replicating System

scientific article published on 23 March 2017

Collection and motif-based prediction of phosphorylation sites in human viruses

scientific article

Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.

scientific article published on August 1997

Comparison of Cas9 activators in multiple species

scientific article published on 23 May 2016

Complementary recognition in condensed DNA: accelerated DNA renaturation.

scientific article published in December 1991

Complete Genome Sequences of T4-Like Bacteriophages RB3, RB5, RB6, RB7, RB9, RB10, RB27, RB33, RB55, RB59, and RB68

scientific article

Complete mitochondrial genomes of living and extinct pigeons revise the timing of the columbiform radiation

scientific article

Composability of regulatory sequences controlling transcription and translation in Escherichia coli

scientific article

Comprehensive AAV capsid fitness landscape reveals a viral gene and enables machine-guided design

scientific article published on 01 November 2019

Computational and experimental identification of C. elegans microRNAs

scientific article

Computational comparison of two draft sequences of the human genome

scientific article published in February 2001

Computational identification of transcription factor binding sites via a transcription-factor-centric clustering (TFCC) algorithm

scientific article published in April 2002

Concerning RNA-guided gene drives for the alteration of wild populations ⬇️

scientific article published on 17 July 2014

Conservation of DNA Regulatory Motifs and Discovery of New Motifs in Microbial Genomes

scientific article published on 01 June 2000

Core commitments for field trials of gene drive organisms

scientific article published on 01 December 2020

Correction: Addressing the ethical issues raised by synthetic human entities with embryo-like features

scientific article published on 13 April 2017

Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae ⬇️

scientific article (publication date: December 2001)

Crispr-mediated Gene Targeting of Human Induced Pluripotent Stem Cells

scientific article published on 4 November 2015

Crystal structure of yeast phenylalanine transfer RNA

Cushing's syndrome mutant PKAL205R exhibits altered substrate specificity

scientific article published on 18 January 2017

DNA sequencing with direct transfer electrophoresis and nonradioactive detection.

scientific article published in January 1993

DNA synthesis and biological security

scientific article published on June 2007

Daisy-chain gene drives for the alteration of local populations

scientific article published on 02 April 2019

Data integration of bulk and single-cell transcriptomics from cerebral organoids and post-mortem brains to identify cell types and cell type specific driver genes in autism

scientific article published on 2 December 2020

Data privacy in the age of personal genomics

scientific article published on 01 October 2019

Databases for gene expression

article

Deciphering the functions and regulation of brain-enriched A-to-I RNA editing

scientific article

Design and characterization of a nanopore-coupled polymerase for single-molecule DNA sequencing by synthesis on an electrode array

scientific article published on 11 October 2016

Design, synthesis, and testing toward a 57-codon genome.

scientific article published in August 2016

Detection via laser desorption and mass spectrometry of multiplex electrophore-labeled albumin ⬇️

scientific article published on January 1, 1997

Developmental barcoding of whole mouse via homing CRISPR

scientific article published on 09 August 2018

Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human

scientific article published on 20 July 2009

Digital genotyping and haplotyping with polymerase colonies

scientific article

Digital quantitative measurements of gene expression

scientific article published on April 2004

Direct mutagenesis of thousands of genomic targets using microarray-derived oligonucleotides

scientific article published on 20 June 2014

Discovering functional transcription-factor combinations in the human cell cycle

scientific article published on June 2005

Discrimination between paralogs using microarray analysis: application to the Yap1p and Yap2p transcriptional networks

scientific article

Dissecting limiting factors of the Protein synthesis Using Recombinant Elements (PURE) system

scientific article published on 9 May 2017

Efficient Reassignment of a Frequent Serine Codon in Wild-Type Escherichia coli

scientific article published on 6 November 2015

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

scientific article

Efficient microRNA capture and bar-coding via enzymatic oligonucleotide adenylation

scientific article published in September 2008

Efficient, footprint-free human iPSC genome editing by consolidation of Cas9/CRISPR and piggyBac technologies

scientific article published on 08 December 2016

Electrophore Mass Tag Dideoxy DNA Sequencing ⬇️

scientific article published on September 1, 1997

Elevated coding mutation rate during the reprogramming of human somatic cells into induced pluripotent stem cells

scientific article published in March 2012

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

scientific article published on 06 September 2016

Enabling large-scale genome editing at repetitive elements by reducing DNA nicking

scientific article published on 21 April 2020

Engineered Living Materials For Sustainability

scientific article published on 13 December 2022

Engineering Ca<sup>2+</sup>-Dependent DNA Polymerase Activity

scientific article published on 19 October 2023

Engineering allostery

scientific article

Engineering an allosteric transcription factor to respond to new ligands

scientific article published on 21 December 2015

Engineering and optimising deaminase fusions for genome editing

scientific article published on 2 November 2016

Engineering posttranslational proofreading to discriminate nonstandard amino acids.

scientific article published on 4 January 2018

Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection

scientific article

Erratum: Corrigendum: Biocontainment of genetically modified organisms by synthetic protein design

scientific article published in Nature

Erratum: Corrigendum: Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

article

Escherichia coli gene expression responsive to levels of the response regulator EvgA.

scientific article

Essential genes as antimicrobial targets and cornerstones of synthetic biology

scientific article published on 30 August 2012

Establishing a Cell-Free Vibrio natriegens Expression System

scientific article published on 12 September 2018

Ethical and practical guidelines for reporting genetic research results to study participants: updated guidelines from a National Heart, Lung, and Blood Institute working group

scientific article

Evidence for large diversity in the human transcriptome created by Alu RNA editing

scientific article published on 8 September 2009

Evolthon: A community endeavor to evolve lab evolution

scientific article published on 29 March 2019

Evolution-guided optimization of biosynthetic pathways

scientific article

Evolutionary dynamics of CRISPR gene drives

scientific article

Expansion Sequencing: Spatially Precise In Situ Transcriptomics in Intact Biological Systems

scientific article published on 15 May 2020

Extensive germline genome engineering in pigs

scientific article published on 21 September 2020

Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases

scientific article

Extensive sequencing of seven human genomes to characterize benchmark reference materials

scientific article

Extracellular Vesicle Isolation and Analysis by Western Blotting

scientific article published in January 2017

Filling gaps in a metabolic network using expression information

scientific article published in August 2004

Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation

scientific article

Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues.

scientific article

Fluorescent in situ sequencing on polymerase colonies

scientific article

From Annotated Genomes to Metabolic Flux Models and Kinetic Parameter Fitting ⬇️

scientific article published on January 1, 2003

From Designing the Molecules of Life to Designing Life: Future Applications Derived from Advances in DNA Technologies

scientific article published on 9 January 2018

From genetic privacy to open consent

scientific article

Functional characterization of the antibiotic resistance reservoir in the human microflora

scientific article

Functional genomics of the rapidly replicating bacterium Vibrio natriegens by CRISPRi

scientific article published on 08 April 2019

Fungal lysis by a soil bacterium fermenting cellulose

scientific article published on 4 May 2014

Gene expression profiling reveals progesterone-mediated cell cycle and immunoregulatory roles of Hoxa-10 in the preimplantation uterus

scientific article

Gene synthesis by circular assembly amplification

scientific article published on 25 November 2007

Generation of functional human hepatic endoderm from human induced pluripotent stem cells

scientific article

Genetically encoded sensors enable real-time observation of metabolite production

scientific article published on 8 February 2016

Genome and Transcriptome of Clostridium phytofermentans, Catalyst for the Direct Conversion of Plant Feedstocks to Fuels

scientific article published on 2 June 2015

Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA).

scientific article

Genome editing in human stem cells

scientific article published on January 2014

Genome engineering

scientific article

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

scientific article

Genome-scale metabolic model of Helicobacter pylori 26695.

scientific article published on August 2002

Genome-scale promoter engineering by coselection MAGE

scientific article

Genome-wide co-occurrence of promoter elements reveals a cis-regulatory cassette of rRNA transcription motifs in Saccharomyces cerevisiae

scientific article published on November 2002

Genome-wide expression dynamics of a marine virus and host reveal features of co-evolution

scientific article

Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing

scientific article

Genome-wide inactivation of porcine endogenous retroviruses (PERVs).

scientific article

Genomic analysis of LexA binding reveals the permissive nature of the Escherichia coli genome and identifies unconventional target sites

scientific article

Genomic analysis of the hydrocarbon-producing, cellulolytic, endophytic fungus Ascocoryne sarcoides

scientific article

Genomic sequencing ⬇️

scientific article published on April 1, 1984

Genomic studies with Escherichia coli MelR protein: applications of chromatin immunoprecipitation and microarrays.

scientific article

Genomically recoded organisms expand biological functions

scientific article

Genomics is mired in misunderstanding

scientific article published in Nature

Global RNA half-life analysis in Escherichia coli reveals positional patterns of transcript degradation

scientific article

Global citizen deliberation on genome editing

scientific article published on 01 September 2020

Global gene expression of Prochlorococcus ecotypes in response to changes in nitrogen availability

scientific article

HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy

scientific article

Harvard Personal Genome Project: lessons from participatory public research

scientific article published on 28 February 2014

Heritable custom genomic modifications in Caenorhabditis elegans via a CRISPR-Cas9 system

scientific article published on 26 August 2013

Heritable genome editing in C. elegans via a CRISPR-Cas9 system

scientific article

Heterologous erythromycin production across strain and plasmid construction.

scientific article published on 28 September 2017

High-fidelity gene synthesis by retrieval of sequence-verified DNA identified using high-throughput pyrosequencing

scientific article

High-resolution antibody dynamics of vaccine-induced immune responses

scientific article (publication date: April 2014)

High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR-Cas9 in yeast

scientific article published on 21 May 2018

High-throughput multiplex sequencing of miRNA

scientific article

Highly efficient Cas9-mediated transcriptional programming

scientific article

Highly multiplexed subcellular RNA sequencing in situ

scientific article

Hippocrates revisited? Old ideals and new realities

scientific article published on January 2008

How accurate can genetic predictions be?

scientific article

How collaboration between bioethicists and neuroscientists can advance research

Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays

scientific article

Identification of a Novel Set of Genes Regulated by a Unique Liver X Receptor-α-mediated Transcription Mechanism

scientific article published in Journal of Biological Chemistry

Identification of foreign gene sequences by transcript filtering against the human genome

scientific article

Identification of many microRNAs that copurify with polyribosomes in mammalian neurons

scientific article

Identifying metabolic enzymes with multiple types of association evidence

scientific article published on 29 March 2006

Identifying regulatory mechanisms using individual variation reveals key role for chromatin modification

scholarly article

Identifying regulatory networks by combinatorial analysis of promoter elements

scientific article (publication date: October 2001)

Imaging of Isolated Extracellular Vesicles Using Fluorescence Microscopy

scientific article published in January 2017

Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures

scientific article published on 05 June 2020

Improved bacterial recombineering by parallelized protein discovery

scientific article published on 28 May 2020

Improved cell-free RNA and protein synthesis system

scientific article

Improving lambda red genome engineering in Escherichia coli via rational removal of endogenous nucleases

scientific article

Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics

scientific article

Improving molecular cancer class discovery through sparse non-negative matrix factorization

scientific article published in November 2005

In situ genome sequencing resolves DNA sequence and structure in intact biological samples

scientific article published on 31 December 2020

In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation

scientific article published on 25 June 2013

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

scientific article published on 31 December 2015

Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9.

scientific article

Information access. Raw personal data: providing access

scientific article

Insights into the evolution of longevity from the bowhead whale genome ⬇️

scientific article

Integrating B cell lineage information into statistical tests for detecting selection in Ig sequences

scientific article published on 27 December 2013

Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers

scientific article

Korean Genome Project: 1094 Korean personal genomes with clinical information

scientific article published on 27 May 2020

Lambda red recombineering in Escherichia coli occurs through a fully single-stranded intermediate.

scientific article

Large scale bacterial gene discovery by similarity search.

scientific article published on June 1994

Large-scale DNA editing of retrotransposons accelerates mammalian genome evolution.

scientific article published in November 2011

Large-scale de novo DNA synthesis: technologies and applications

scientific article

Large-scale identification of genetic design strategies using local search

scientific article published on 18 August 2009

Let us go forth and safely multiply

scientific article

Light and carbon: Synthetic biology toward new cyanobacteria-based living biomaterials

Lineage barcoding in mice with homing CRISPR

scientific article published on 10 March 2021

Localization to the proteasome is sufficient for degradation

scientific article published on 23 March 2004

Long-range polony haplotyping of individual human chromosome molecules

scientific article published on 19 February 2006

Mammalian ultraconserved elements are strongly depleted among segmental duplications and copy number variants

scientific article published on 24 September 2006

Manipulating replisome dynamics to enhance lambda Red-mediated multiplex genome engineering.

scientific article

MapQuant: open-source software for large-scale protein quantification

scientific article published on March 2006

Matching phenotypes to whole genomes: Lessons learned from four iterations of the personal genome project community challenges.

scientific article published on 23 May 2017

Mathematical models of diffusion-constrained polymerase chain reactions: basis of high-throughput nucleic acid assays and simple self-organizing systems

scientific article published in May 2004

Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip

article

Measuring absolute expression with microarrays with a calibrated reference sample and an extended signal intensity range

scientific article

Measuring cation dependent DNA polymerase fidelity landscapes by deep sequencing

scientific article published in 2012

Meta-analysis of age-related gene expression profiles identifies common signatures of aging.

scientific article

Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization ⬇️

scientific article published on October 1, 1997

Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx.

scientific article published on March 2000

Millstone: software for multiplex microbial genome analysis and engineering

scientific article

Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions

scientific article published on 22 September 2008

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

scientific article

Modified bases enable high-efficiency oligonucleotide-mediated allelic replacement via mismatch repair evasion

scientific article

Modular epistasis in yeast metabolism

scientific article published on 12 December 2004

Molecular recordings by directed CRISPR spacer acquisition

scientific article published on 09 June 2016

Molecular threading: mechanical extraction, stretching and placement of DNA molecules from a liquid-air interface

scientific article

Molecular weight assessment of proteins in total proteome profiles using 1D-PAGE and LC/MS/MS

scientific article

Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells

scientific article

Multiple haplotype-resolved genomes reveal population patterns of gene and protein diplotypes

scientific article

Multiplex DNA Sequencing ⬇️

scientific article published on April 8, 1988

Multiplex Sequencing of 1.5 Mb of the Mycobacterium leprae Genome ⬇️

scientific article published on August 1, 1997

Multiplex Single-Molecule Kinetics of Nanopore-Coupled Polymerases

scientific article published on 28 December 2020

Multiplex amplification of large sets of human exons

scientific article

Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9.

scientific article published on August 2013

Multiplex base editing to convert TAG into TAA codons in the human genome

scientific article published in 2022

Multiplex padlock targeted sequencing reveals human hypermutable CpG variations

scientific article published on 12 June 2009

Multiplex single-molecule interaction profiling of DNA-barcoded proteins

scientific article

Multiplexed Engineering in Biology

scientific article published on 11 January 2016

Multiplexed genome engineering and genotyping methods applications for synthetic biology and metabolic engineering

scientific article

Multiplexed in vivo His-tagging of enzyme pathways for in vitro single-pot multienzyme catalysis

scientific article

Mutants of Cre recombinase with improved accuracy

scientific article

Nanoscale imaging of RNA with expansion microscopy

scientific article published on 04 July 2016

Nanotools for neuroscience and brain activity mapping

scientific article published on 20 March 2013

Natural reassignment of CUU and CUA sense codons to alanine in Ashbya mitochondria

scientific article published on 17 September 2013

Neuroscience. The brain activity map

scientific article published on 07 March 2013

Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing.

scientific article published on 20 October 2015

New class of biological detectors for WIMPs

New technologies for integrating genomic, environmental and trait data

scientific article

Next stop for the CRISPR revolution: RNA-guided epigenetic regulators

scientific article published on June 2016

Next-generation carrier screening

scientific article published on 13 June 2013

Next-generation digital information storage in DNA.

scientific article

Nucleic acid memory.

scientific article published in March 2016

Nucleotide-time alignment for molecular recorders

scientific article

On the complete determination of biological systems

scientific article published on 01 June 2003

On the design of clone-based haplotyping

scientific article published on January 2013

Opportunities, Barriers, and a Strategy for Overcoming Translational Challenges to Therapeutic Nucleic Acid Nanotechnology

scientific article published on 24 July 2020

Optical control of mammalian endogenous transcription and epigenetic states

scientific journal article

Optimization of scarless human stem cell genome editing

scientific article published on 31 July 2013

Optimizing complex phenotypes through model-guided multiplex genome engineering

scientific article published on 25 May 2017

Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder

scientific article published on 10 June 2022

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

scientific article

Orthogonally induced differentiation of stem cells for the programmatic patterning of vascularized organoids and bioprinted tissues

scientific article published on 24 March 2022

Overcoming Challenges in Engineering the Genetic Code

scientific article published on 05 September 2015

Overview of DNA sequencing strategies

scientific article published on January 2008

Overview of DNA sequencing strategies

scientific article published on October 2011

PEPPeR, a platform for experimental proteomic pattern recognition.

scientific article published on 19 July 2006

Panel discussion: can there be a biomarker for sleepiness?

scientific article

Parallel competition analysis of Saccharomyces cerevisiae strains differing by a single base using polymerase colonies

scientific article

Patterns and implications of gene gain and loss in the evolution of Prochlorococcus

scientific article published in December 2007

Performance of optimized noncanonical amino acid mutagenesis systems in the absence of release factor 1.

scientific article

Perspective: Encourage the innovators

scientific article published in December 2015

PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis

scientific article

Phased whole-genome genetic risk in a family quartet using a major allele reference sequence

scientific article

Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage

scientific article published on 16 October 2020

Photosynthesis genes in marine viruses yield proteins during host infection

scientific article

Physical principles for scalable neural recording.

scientific article

Please Reanimate

scientific article published on 01 September 2013

Pleiotropic mutations within two yeast mitochondrial cytochrome genes block mRNA processing

scientific article published on December 1979

Pluripotent stem cell-derived CAR-macrophage cells with antigen-dependent anti-cancer cell functions

scientific article published on 11 November 2020

Polony multiplex analysis of gene expression (PMAGE) in mouse hypertrophic cardiomyopathy

scientific article

Porcine genome engineering for xenotransplantation

scientific article published on 07 April 2020

Precise Cas9 targeting enables genomic mutation prevention.

scientific article published on 19 March 2018

Precise manipulation of chromosomes in vivo enables genome-wide codon replacement

scientific article (publication date: 15 July 2011)

Precision Chemistry for Precision Medicine

scientific article

Predicting phenotype from patterns of annotation

scientific article published on January 2003

Predicting protein post-translational modifications using meta-analysis of proteome scale data sets

scientific article

Prediction of similarly acting cis-regulatory modules by subsequence profiling and comparative genomics in Drosophila melanogaster and D.pseudoobscura

scientific article published on 14 May 2004

Preferred in vivo ubiquitination sites

scientific article published on 15 July 2004

Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes

scientific article

Probing the limits of genetic recoding in essential genes.

scientific article

Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

scientific article published on 6 February 2017

Programming cells by multiplex genome engineering and accelerated evolution

scientific article

Protein interaction discovery using parallel analysis of translated ORFs (PLATO)

scientific article

Proteogenomic mapping as a complementary method to perform genome annotation

scientific article published on January 2004

Proteome-wide systems analysis of a cellulosic biofuel-producing microbe

scientific article

Public access to genome-wide data: five views on balancing research with privacy and protection

scientific article (publication date: October 2009)

Publisher Correction: Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder

scientific article published on 14 July 2020

Puzzle Imaging: Using Large-Scale Dimensionality Reduction Algorithms for Localization ⬇️

scientific article

Quantification of microRNA expression with next-generation sequencing

scientific article published on July 2013

Quantifying DNA-protein interactions by double-stranded DNA arrays.

scientific article

Quantitative monitoring by polymerase colony assay of known mutations resistant to ABL kinase inhibitors

scientific article published on 06 August 2007

Quantitative morphological signatures define local signaling networks regulating cell morphology.

scientific article

Quantitative whole-genome analysis of DNA-protein interactions by in vivo methylase protection in E. coli ⬇️

scientific article published on June 1, 1998

RNA - ligand interactions:(I) magnesium binding sites in yeast tRNAPhe ⬇️

scientific article published on August 1, 1977

RNA expression analysis using a 30 base pair resolution Escherichia coli genome array

scientific article (publication date: December 2000)

RNA sequencing reveals differential expression of mitochondrial and oxidation reduction genes in the long-lived naked mole-rat when compared to mice

scientific article

RNA-guided human genome engineering via Cas9

scientific article

Rapid Sequential in Situ Multiplexing with DNA Exchange Imaging in Neuronal Cells and Tissues

scientific article published on 21 September 2017

Rapid neurogenesis through transcriptional activation in human stem cells.

scientific article

Rapid prototyping of 3D DNA-origami shapes with caDNAno

scientific article

Rapidly evolving homing CRISPR barcodes

scientific article

Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder

scientific article

Rational optimization of tolC as a powerful dual selectable marker for genome engineering

scientific article published on 22 January 2014

Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing

scientific article published on 01 October 2020

Reading and writing omes ⬇️

scientific article published on January 1, 2013

Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array

scientific article published on 18 April 2016

Realizing the potential of synthetic biology

scientific article published on 12 March 2014

Recent progress in engineering human-associated microbiomes

scientific article

Recoding the genetic code with selenocysteine.

scientific article published on January 2014

Redirector: designing cell factories by reconstructing the metabolic objective

scientific article

Regulatory network of acid resistance genes in Escherichia coli

scientific article

Regulatory networks revealed by transcriptional profiling of damaged Saccharomyces cerevisiae cells: Rpn4 links base excision repair with proteasomes

scientific article

Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells

scientific article published on November 2006

Release Factor Inhibiting Antimicrobial Peptides Improve Nonstandard Amino Acid Incorporation in Wild-type Bacterial Cells

scientific article published on 30 June 2020

Reprogramming of T cells from human peripheral blood

scientific article

Reprogramming to recover youthful epigenetic information and restore vision

scientific article published on 02 December 2020

Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA

scientific article published on 24 July 2020

SDip: A novel graph-based approach to haplotype-aware assembly based structural variant calling in targeted segmental duplications sequencing

scientific article published on 26 February 2020

Safeguarding CRISPR-Cas9 gene drives in yeast

scientific article

Scalable Device for Automated Microbial Electroporation in a Digital Microfluidic Platform.

scientific article

Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips

scientific article

Secondary structural complementarity between DNA and proteins ⬇️

scientific article published on April 1, 1977

Sequencing genomes from single cells by polymerase cloning

scientific article

Sequencing thoroughbreds.

scientific article

Simulating Serial-Target Antibacterial Drug Synergies Using Flux Balance Analysis

scientific article

Simultaneous Discovery of Cell-Free DNA and the Nucleosome Ladder.

scientific article published in May 2018

Single molecule profiling of alternative pre-mRNA splicing

scientific article

Single molecule profiling of tau gene expression in Alzheimer's disease

scientific article published on 28 August 2007

Single-Cell CRISPR-Based Lineage Tracing in Mice

scientific article published on 15 November 2019

Spatial Sequencing: A Perspective

scientific article published on 29 April 2020

Spatial information in large-scale neural recordings

scientific article published on January 2014

Spontaneous CRISPR loci generation in vivo by non-canonical spacer integration

scientific article published on 29 January 2018

Stable gene targeting in human cells using single-strand oligonucleotides with modified bases

scientific article (publication date: 2012)

Statistical analysis of molecular signal recording

scientific article (publication date: 2013)

Strategies to identify and edit improvements in synthetic genome segments episomally

Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA.

scientific article published on October 2012

Synthetic biology projects in vitro

scientific article published on 6 December 2006

Synthetic biosensors for precise gene control and real-time monitoring of metabolites

scientific article published on 7 July 2015

Synthetic gene networks that count

scientific article

Syntrophic exchange in synthetic microbial communities

scientific article

Systematic determination of genetic network architecture

scientific article (publication date: July 1999)

Systematic identification of edited microRNAs in the human brain

scientific article

TBDB: a database of structurally annotated T-box riboswitch:tRNA pairs

scientific article published on 03 September 2020

Targeted Intracellular Degradation of SARS-CoV-2 via Computationally-Optimized Peptide Fusions

scientific article published on 31 August 2020

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

scientific article (publication date: April 2009)

Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells

scientific article published on 26 November 2014

Targeted gene inactivation in Clostridium phytofermentans shows that cellulose degradation requires the family 9 hydrolase Cphy3367

scientific article (publication date: December 2009)

Targeted intracellular degradation of SARS-CoV-2 via computationally optimized peptide fusions

scientific article published on 23 November 2020

Terminator-free template-independent enzymatic DNA synthesis for digital information storage.

scientific article published on 3 June 2019

The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing

scientific article published on 20 August 2020

The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies

scientific article

The Future of Multiplexed Eukaryotic Genome Engineering.

scientific article

The Genome Project–Write ⬇️

scientific article

The Human Ageing Genomic Resources: online databases and tools for biogerontologists.

scientific article

The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations

scientific article

The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop

scientific article

The amino-acid mutational spectrum of human genetic disease

scientific article

The biosecurity benefits of genetic engineering attribution

scientific article published on 08 December 2020

The brain activity map project and the challenge of functional connectomics

scientific article

The challenges of sequencing by synthesis

scientific article

The cleavage site of the restriction endonuclease Ava II ⬇️

scientific article published on July 1, 1978

The complete genome and proteome of Mycoplasma mobile

scientific article

The inherent challenges of classifying senescence-Response

scientific article

The most conserved genome segments for life detection on Earth and other planets

scientific article published on 14 October 2008

The promise of organ and tissue preservation to transform medicine

scientific article published on June 2017

The role of replicates for error mitigation in next-generation sequencing

scientific article

The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation

scientific article published on October 2011

The transition between transcriptional initiation and elongation in E. coli is highly variable and often rate limiting.

scientific article

The whale shark genome reveals how genomic and physiological properties scale with body size

scientific article published on 04 August 2020

The whole genome sequences and experimentally phased haplotypes of over 100 personal genomes.

scientific article

Thoughts on theManchester Manifesto

Tools for the Microbiome: Nano and Beyond

scientific article published on 22 December 2015

Towards in situ sequencing for life detection

Towards next-generation cell factories by rational genome-scale engineering

Towards synthesis of a minimal cell

scientific article

Transcriptional profiling of CD4 T cells identifies distinct subgroups of HIV-1 elite controllers

scientific article

Transparency is key to ethical vaccine research

scientific article

Tuberculosis drug resistance mutation database

scientific article

Unified rational protein engineering with sequence-based deep representation learning

scientific article published on 21 October 2019

Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability

scientific article published in April 2023

Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach

scientific article

Using bacteria to determine protein kinase specificity and predict target substrates

scientific article

Yeast oligo-mediated genome engineering (YOGE).

scientific article

pLogo: a probabilistic approach to visualizing sequence motifs

scientific article published on 6 October 2013

sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity.

scientific article

αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model

scientific article published on 01 March 2020

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