List of works - Ma-Li Wong

A molecular mechanism for stress-induced alterations in susceptibility to disease

scientific article published on July 1995

ADORA1-driven brain-sympathetic neuro-adipose connections control body weight and adipose lipid metabolism

scientific article published on 16 October 2020

Acute systemic inflammation up-regulates secretory sphingomyelinase in vivo: a possible link between inflammatory cytokines and atherogenesis

scientific article

Advances in depression research: 2011 ⬇️

scientific article published on July 1, 2011

Advances in the pharmacogenomics of adverse drug reactions

scientific article published on 01 January 2002

Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity

scientific article

Approaches to dissecting mechanisms of adverse drug reactions in psychiatry: clozapine-binding sites in the bone marrow

scientific article published in January 2003

Approaching the shared biology of obesity and depression: the stress axis as the locus of gene-environment interactions

scientific article published on August 2006

Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans

scientific article

Association study of the serotonin transporter promoter polymorphism and mirtazapine antidepressant response in major depressive disorder

article

Autoimmunity in autism

scientific article published on 01 January 2002

Back to where it all started: monoamines and behavior--from drug responses to genes

scientific article published in May 2004

Brain iNOS: current understanding and clinical implications

scientific article

Brain-derived neurotrophic factor (BDNF) in stress and affective disorders

scientific article published in January 2002

Brain-derived neurotrophic factor gene polymorphisms and mirtazapine responses in Koreans with major depression.

scientific article published on 3 June 2009

Brain-derived neurotrophic factor in depression: a male problem?

scientific article

CYP2C9 allele frequency differences between populations of Mexican-Mestizo, Mexican-Tepehuano, and Spaniards.

scientific article

Candidate biomarkers for systemic inflammatory response syndrome and inflammation: a pathway for novel translational therapeutics

scientific article published on 29 May 2010

Cardiac implications of increased arterial entry and reversible 24-h central and peripheral norepinephrine levels in melancholia

scientific article

Caspase 1 deficiency reduces inflammation-induced brain transcription

scholarly article

Changes in insulin sensitivity during leptin replacement therapy in leptin-deficient patients

scientific article published on 14 October 2008

Characterization and functional expression of a somatostatin receptor coupled to adenylyl cyclase

scientific article published in June 1993

Chronic administration of the non-peptide CRH type 1 receptor antagonist antalarmin does not blunt hypothalamic-pituitary-adrenal axis responses to acute immobilization stress

scientific article

Chronic imipramine downregulates cyclic AMP signaling in rat hippocampus.

scientific article published in February 2009

Circadian interleukin-6 secretion and quantity and depth of sleep

scientific article published in August 1999

Circumscribed lesion of the medial forebrain bundle area causes structural impairment of lymphoid organs and severe depression of immune function in rats

scientific article published in September 1998

Complexity and pharmacogenomics

scientific article published in January 2002

Conceptualizing depression

scientific article published on 01 January 2002

Congenital leptin deficiency: diagnosis and effects of leptin replacement therapy

scientific article

Corticotropin releasing hormone in the pathophysiology of melancholic and atypical depression and in the mechanism of action of antidepressant drugs

scientific article published on December 1995

Deconvolution of insulin secretion, insulin hepatic extraction post-hepatic delivery rates and sensitivity during 24-hour standardized meals: time course of glucose homeostasis in leptin replacement treatment

scientific article published on 22 August 2008

Depression and anxiety symptoms in diabetic patients on continuous subcutaneous insulin infusion (CSII).

scientific article published in November 2005

Depression and cardiovascular disease: co-occurrence or shared genetic substrates?

scientific article published on 01 January 2002

Depression and obesity treatments are life saving

scientific article

Depression, antidepressants and suicidality: a critical appraisal

scientific article

Differential effects of kindled and electrically induced seizures on a glutamate receptor (GluR1) gene expression

scientific article published in March 1993

Dynamics of plasma proteome during leptin-replacement therapy in genetically based leptin deficiency

scientific article published on 11 May 2010

Effect of leptin replacement on brain structure in genetically leptin-deficient adults

scientific article

Effects of Leptin on Lipid Metabolism

scientific article published on 11 July 2008

Effects of leptin on intake of specific micro- and macronutrients in a woman with leptin gene deficiency studied off and on leptin at stable body weight

scientific article

Effects of leptin replacement on macro- and micronutrient preferences

scientific article published on 07 August 2007

Effects of leptin replacement on risk factors for cardiovascular disease in genetically leptin-deficient subjects.

scientific article published on 22 August 2008

Elevated cortisol levels and increased rates of diabetes and mood symptoms in Soviet Union-born Jewish immigrants to Germany

scientific article published in November 2005

Elevated plasma prolactin in abstinent methamphetamine-dependent subjects

scientific article

Elevated stress-hemoconcentration in major depression is normalized by antidepressant treatment: secondary analysis from a randomized, double-blind clinical trial and relevance to cardiovascular disease risk

scientific article

Endogenous interleukin-1 receptor antagonist is neuroprotective

scientific article

Expression of corticotropin releasing hormone receptors type I and type II mRNA in suicide victims and controls

scientific article published on 01 September 2001

Extracorporeal apheresis therapy for Alzheimer disease-targeting lipids, stress, and inflammation

scientific article published on 08 October 2019

Focal cerebral ischemia induces CRH mRNA in rat cerebral cortex and amygdala

scientific article published on 01 September 1995

From monoamines to genomic targets: a paradigm shift for drug discovery in depression

scientific article published on February 2004

Global meta-analysis of the C-11377G alteration in the ADIPOQ gene indicates the presence of population-specific effects: challenge for global health initiatives

scientific article published on 4 March 2008

Human leptin levels are pulsatile and inversely related to pituitary-adrenal function.

scientific article

Hypothalamic-pituitary-end organ function in women with bipolar depression

scientific article published on 20 February 2007

IL-1 receptor type I gene expression in the amygdala of inflammatory susceptible Lewis and inflammatory resistant Fischer rats

scientific article published in December 2001

IL-1β, IL-1 receptor type I and iNOS gene expression in rat brain vasculature and perivascular areas

article

Identification of hypothalamic transcripts upregulated by antidepressants

scientific article published in December 1996

Identification, characterization, and gene expression profiling of endotoxin-induced myocarditis

scientific article

Immunological assays for understanding neuroimmune interactions

scientific article

Inducible nitric oxide synthase gene expression in the brain during systemic inflammation

scientific article

Induction of constitutive heat shock protein 73 mRNA in the dentate gyrus by seizures

scientific article published in March 1992

Interleukin (IL) 1beta, IL-1 receptor antagonist, IL-10, and IL-13 gene expression in the central nervous system and anterior pituitary during systemic inflammation: pathophysiological implications

scientific article

Interleukin 1 receptor antagonist gene expression in rat pituitary in the systemic inflammatory response syndrome: pathophysiological implications

scientific article

Interleukin 1β and fever

scientific article published on 01 December 1996

Is the worldwide epidemic of obesity a communicable feature of globalization?

scientific article published on 05 September 2008

Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders

scientific article published on 02 December 2020

Leptin

scientific article published on 01 December 1998

Leptin replacement alters brain response to food cues in genetically leptin-deficient adults

scientific article

Leptin replacement improves cognitive development

scientific article

Leptin replacement prevents weight loss-induced metabolic adaptation in congenital leptin-deficient patients

scientific article

Localization of corticotropin-releasing hormone (CRH) receptor mRNA in adult rat brain by in situ hybridization histochemistry

scientific article published in November 1994

Localization of interleukin 1 type I receptor mRNA in rat brain.

scientific article

Localization of interleukin-1 beta converting enzyme mRNA in rat brain vasculature: evidence that the genes encoding the interleukin-1 system are constitutively expressed in brain blood vessels. Pathophysiological implications.

scientific article

Long-term body weight outcomes of antidepressant-environment interactions

scientific article

Lower frequency of CYP2C9*2 in Mexican-Americans compared to Spaniards.

scientific article published in January 2004

Mice lacking Casp1, Ifngr and Nos2 genes exhibit altered depressive- and anxiety-like behaviour, and gut microbiome composition

article

Microanalysis of eating behavior of three leptin deficient adults treated with leptin therapy

scientific article published in August 2005

Modeling of the temporal patterns of fluoxetine prescriptions and suicide rates in the United States

scientific article

Molecular Psychiatry, August 2020: new impact factor, and highlights of recent advances in psychiatry, including an overview of the brain's response to stress during infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

scientific article published on 28 July 2020

Neutrophil-activating peptide-1/interleukin-8 mRNA is localized in rat hypothalamus and hippocampus

scientific article published in September 1992

Pathways and mechanisms for cytokine signaling of the central nervous system ⬇️

scientific article published on December 15, 1997

Patient-oriented investigation in pharmacogenomics

scientific article published on 01 January 2002

Peripheral is Central to the question

scientific article published on 01 May 2005

Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response

scientific article

Pharmacogenomics in psychiatry: clinical issues to be considered

scientific article published in July 2005

Pharmacogenomics in psychiatry: genomic considerations

scientific article published in August 2005

Pharmacogenomics of antidepressant treatment effects ⬇️

scientific article published on January 1, 2011

Pharmacogenomics of antidepressants: what is next?

scientific article published on 01 May 2010

Pharmacogenomics of neuroimmune interactions in human psychiatric disorders

scientific article published on 3 August 2007

Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults

scientific article

Phosphodiesterase genes and antidepressant treatment response: a review

scientific article published on January 2009

Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response

scientific article

Polyamine effects upon N-methyl-D-aspartate receptor functioning: differential alteration by glutamate and glycine site antagonists.

scientific article published in October 1991

Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant response

scientific article published on 27 May 2008

Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: relation to hypercortisolism and corticotropin-releasing hormone

scientific article

Pulsatility of 24-hour concentrations of circulating interleukin-1-alpha in healthy women: analysis of integrated basal levels, discrete pulse properties, and correlation with simultaneous interleukin-2 concentrations.

scientific article published in July 1994

Repeated antidepressant therapy increases cyclic GMP signaling in rat hippocampus

scientific article

Research and treatment approaches to depression

scientific article

Ritanserin antagonism of m-chlorophenylpiperazine effects in neuroleptic-free schizophrenics patients: support for serotonin-2 receptor modulation of schizophrenia symptoms

scientific article published on 5 April 2002

Sequence and function in pharmacogenomics

scientific article

Sequence polymorphisms of MC1R gene and their association with depression and antidepressant response

scientific article

Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans

scientific article

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis

scientific article published on 07 May 2020

Sex differences in circulating human leptin pulse amplitude: clinical implications

scientific article

Simultaneous and continuous 24-hour plasma and cerebrospinal fluid leptin measurements: dissociation of concentrations in central and peripheral compartments.

scientific article published in January 2004

St John's wort and imipramine-induced gene expression profiles identify cellular functions relevant to antidepressant action and novel pharmacogenetic candidates for the phenotype of antidepressant treatment response

scientific article published on March 2004

Stress-inducible-stem cells: a new view on endocrine, metabolic and mental disease?

scientific article published on 21 September 2018

Suicidality Scores During Double-Blind Fluoxetine and Desipramine Treatment in Mexican Americans

article

Synchronicity of frequently sampled thyrotropin (TSH) and leptin concentrations in healthy adults and leptin-deficient subjects: evidence for possible partial TSH regulation by leptin in humans

scientific article

Synchronicity of frequently sampled, 24-h concentrations of circulating leptin, luteinizing hormone, and estradiol in healthy women.

scientific article

Ten years of leptin replacement therapy ⬇️

scientific article published on March 17, 2011

The COVID-19 pandemic and epidemiologic insights from recession-related suicide mortality

scientific article published on 01 September 2020

The Metabolic Syndrome - a global challenge for prevention

scientific article published on November 2007

The brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism and depression in Mexican-Americans

scientific article

The evolution of signaling complexity suggests a mechanism for reducing the genomic search space in human association studies

scientific article

The gene encoding for the novel transacting factor proopiomelanocortin corticotropin-releasing hormone responsive element binding protein 1 (PCRH-REB-1) is constitutively expressed in rat pituitary and in discrete brain regions containing CRH or CRH

scientific article published on 01 October 1995

The gut microbiome from patients with schizophrenia modulates the glutamate-glutamine-GABA cycle and schizophrenia-relevant behaviors in mice

scientific article published on 07 February 2019

The gut microbiome modulates gut-brain axis glycerophospholipid metabolism in a region-specific manner in a nonhuman primate model of depression

scientific article published on 06 May 2020

The hypothalamic-pituitary-adrenal axis in anorexia nervosa

scientific article

The impact of the nonpeptide corticotropin-releasing hormone antagonist antalarmin on behavioral and endocrine responses to stress

scientific article

The nitric oxide hypothesis of aging

scientific article published in November 1998

The procognitive effects of leptin in the brain and their clinical implications

scientific article

The role of inflammatory mediators in the biology of major depression: central nervous system cytokines modulate the biological substrate of depressive symptoms, regulate stress-responsive systems, and contribute to neurotoxicity and neuroprotection

scientific article

Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia

scientific article published on 14 September 2020

Translational research in psychiatry: pitfalls and opportunities for career development

article

Will pharmacogenomics guide clinical practice?

scientific article published on 01 January 2002

cGMP Signaling, Phosphodiesterases and Major Depressive Disorder ⬇️

scientific article published on December 1, 2011

List of works by Ma-Li Wong

A molecular mechanism for stress-induced alterations in susceptibility to disease

ADORA1-driven brain-sympathetic neuro-adipose connections control body weight and adipose lipid metabolism

Acute systemic inflammation up-regulates secretory sphingomyelinase in vivo: a possible link between inflammatory cytokines and atherogenesis

Advances in depression research: 2011 ⬇️

Advances in the pharmacogenomics of adverse drug reactions

Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity

Approaches to dissecting mechanisms of adverse drug reactions in psychiatry: clozapine-binding sites in the bone marrow

Approaching the shared biology of obesity and depression: the stress axis as the locus of gene-environment interactions

Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans

Association study of the serotonin transporter promoter polymorphism and mirtazapine antidepressant response in major depressive disorder

Autoimmunity in autism

Back to where it all started: monoamines and behavior--from drug responses to genes

Brain iNOS: current understanding and clinical implications

Brain-derived neurotrophic factor (BDNF) in stress and affective disorders

Brain-derived neurotrophic factor gene polymorphisms and mirtazapine responses in Koreans with major depression.

Brain-derived neurotrophic factor in depression: a male problem?

CYP2C9 allele frequency differences between populations of Mexican-Mestizo, Mexican-Tepehuano, and Spaniards.

Candidate biomarkers for systemic inflammatory response syndrome and inflammation: a pathway for novel translational therapeutics

Cardiac implications of increased arterial entry and reversible 24-h central and peripheral norepinephrine levels in melancholia

Caspase 1 deficiency reduces inflammation-induced brain transcription

Changes in insulin sensitivity during leptin replacement therapy in leptin-deficient patients

Characterization and functional expression of a somatostatin receptor coupled to adenylyl cyclase

Chronic administration of the non-peptide CRH type 1 receptor antagonist antalarmin does not blunt hypothalamic-pituitary-adrenal axis responses to acute immobilization stress

Chronic imipramine downregulates cyclic AMP signaling in rat hippocampus.

Circadian interleukin-6 secretion and quantity and depth of sleep

Circumscribed lesion of the medial forebrain bundle area causes structural impairment of lymphoid organs and severe depression of immune function in rats

Complexity and pharmacogenomics

Conceptualizing depression

Congenital leptin deficiency: diagnosis and effects of leptin replacement therapy

Corticotropin releasing hormone in the pathophysiology of melancholic and atypical depression and in the mechanism of action of antidepressant drugs

Deconvolution of insulin secretion, insulin hepatic extraction post-hepatic delivery rates and sensitivity during 24-hour standardized meals: time course of glucose homeostasis in leptin replacement treatment

Depression and anxiety symptoms in diabetic patients on continuous subcutaneous insulin infusion (CSII).

Depression and cardiovascular disease: co-occurrence or shared genetic substrates?

Depression and obesity treatments are life saving

Depression, antidepressants and suicidality: a critical appraisal

Differential effects of kindled and electrically induced seizures on a glutamate receptor (GluR1) gene expression

Dynamics of plasma proteome during leptin-replacement therapy in genetically based leptin deficiency

Effect of leptin replacement on brain structure in genetically leptin-deficient adults

Effects of Leptin on Lipid Metabolism

Effects of leptin on intake of specific micro- and macronutrients in a woman with leptin gene deficiency studied off and on leptin at stable body weight

Effects of leptin replacement on macro- and micronutrient preferences

Effects of leptin replacement on risk factors for cardiovascular disease in genetically leptin-deficient subjects.

Elevated cortisol levels and increased rates of diabetes and mood symptoms in Soviet Union-born Jewish immigrants to Germany

Elevated plasma prolactin in abstinent methamphetamine-dependent subjects

Elevated stress-hemoconcentration in major depression is normalized by antidepressant treatment: secondary analysis from a randomized, double-blind clinical trial and relevance to cardiovascular disease risk

Endogenous interleukin-1 receptor antagonist is neuroprotective

Expression of corticotropin releasing hormone receptors type I and type II mRNA in suicide victims and controls

Extracorporeal apheresis therapy for Alzheimer disease-targeting lipids, stress, and inflammation

Focal cerebral ischemia induces CRH mRNA in rat cerebral cortex and amygdala

From monoamines to genomic targets: a paradigm shift for drug discovery in depression

Global meta-analysis of the C-11377G alteration in the ADIPOQ gene indicates the presence of population-specific effects: challenge for global health initiatives

Human leptin levels are pulsatile and inversely related to pituitary-adrenal function.

Hypothalamic-pituitary-end organ function in women with bipolar depression

IL-1 receptor type I gene expression in the amygdala of inflammatory susceptible Lewis and inflammatory resistant Fischer rats

IL-1β, IL-1 receptor type I and iNOS gene expression in rat brain vasculature and perivascular areas

Identification of hypothalamic transcripts upregulated by antidepressants

Identification, characterization, and gene expression profiling of endotoxin-induced myocarditis

Immunological assays for understanding neuroimmune interactions

Inducible nitric oxide synthase gene expression in the brain during systemic inflammation

Induction of constitutive heat shock protein 73 mRNA in the dentate gyrus by seizures

Interleukin (IL) 1beta, IL-1 receptor antagonist, IL-10, and IL-13 gene expression in the central nervous system and anterior pituitary during systemic inflammation: pathophysiological implications

Interleukin 1 receptor antagonist gene expression in rat pituitary in the systemic inflammatory response syndrome: pathophysiological implications

Interleukin 1β and fever

Is the worldwide epidemic of obesity a communicable feature of globalization?

Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders

Leptin

Leptin replacement alters brain response to food cues in genetically leptin-deficient adults

Leptin replacement improves cognitive development

Leptin replacement prevents weight loss-induced metabolic adaptation in congenital leptin-deficient patients

Localization of corticotropin-releasing hormone (CRH) receptor mRNA in adult rat brain by in situ hybridization histochemistry

Localization of interleukin 1 type I receptor mRNA in rat brain.

Localization of interleukin-1 beta converting enzyme mRNA in rat brain vasculature: evidence that the genes encoding the interleukin-1 system are constitutively expressed in brain blood vessels. Pathophysiological implications.

Long-term body weight outcomes of antidepressant-environment interactions

Lower frequency of CYP2C9*2 in Mexican-Americans compared to Spaniards.

Mice lacking Casp1, Ifngr and Nos2 genes exhibit altered depressive- and anxiety-like behaviour, and gut microbiome composition

Microanalysis of eating behavior of three leptin deficient adults treated with leptin therapy

Modeling of the temporal patterns of fluoxetine prescriptions and suicide rates in the United States

Molecular Psychiatry, August 2020: new impact factor, and highlights of recent advances in psychiatry, including an overview of the brain's response to stress during infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Neutrophil-activating peptide-1/interleukin-8 mRNA is localized in rat hypothalamus and hippocampus