Search filters

List of works by David Nutt

'Seeing through a glass darkly': casting light on imidazoline 'I' sites

scientific article published in September 1998

19th biennial IPEG Meeting

2-(4,5-Dihydro-1H-imidazol-2-yl)indazole (indazim) derivatives as selective I2 imidazoline receptor ligands ⬇️

scientific article published on October 1, 2003

2-(4,5-Dihydroimidazol-2-yl)benzimidazoles as highly selective imidazoline I2/adrenergic α2 receptor ligands

scientific article published on 16 June 2006

3-(Methoxycarbonyl)-amino-beta-carboline reduces both the sedative and anticonvulsant effects of diazepam

scientific article published in June 1989

3-Methyl-methcathinone: Pharmacokinetic profile evaluation in pigs in relation to pharmacodynamics

scientific article published on 24 March 2015

5-HT radioligands for human brain imaging with PET and SPECT

scientific article

5-HT3 receptors, nausea, and serotonin reuptake inhibition

scientific article published on 01 April 1997

5-Isothiocyanato-2-benzofuranyl-2-imidazoline (BU99006) an irreversible imidazoline(2) binding site ligand: in vitro and in vivo characterisation in rat brain.

scientific article

A Brief Outline of the Use of New Technologies for Treating Substance Use Disorders in the European Union

scientific article

A Lifetime Prevalence of Comorbidity Between Bipolar Affective Disorder and Anxiety Disorders: A Meta-analysis of 52 Interview-based Studies of Psychiatric Population

scientific article

A Proposed Algorithm for Improved Recognition and Treatment of the Depression/Anxiety Spectrum in Primary Care

scientific article

A Review of 3,4-methylenedioxymethamphetamine (MDMA)-Assisted Psychotherapy

article

A U-shaped relationship between systolic blood pressure and panic symptoms: the HUNT study.

scientific article published on 17 January 2012

A [11C]Ro15 4513 PET study suggests that alcohol dependence in man is associated with reduced α5 benzodiazepine receptors in limbic regions

scientific article published on 24 September 2010

A benzodiazepine agonist and contragonist have hypothermic effects in rodents

scientific article published on 01 January 1985

A call to reprioritise metrics to evaluate illicit drug policy

scientific article published in April 2016

A cerebrospinal fluid study of the pathophysiology of panic disorder associated with alcoholism ⬇️

scientific article published on July 1, 1990

A cognitive dysfunction in anxiety and its amelioration by effective treatment with SSRIs

scientific article published on 01 January 1995

A comparison of calcium antagonists and diazepam in reducing ethanol withdrawal tremors

scientific article published on January 1989

A comparison of the effects of a subtype selective and non-selective benzodiazepine receptor agonist in two CO(2) models of experimental human anxiety.

scientific article published on 18 June 2008

A comparison of the effects of phenelzine treatment with moclobemide treatment on cardiovascular reflexes

scientific article published on 01 November 1995

A new approach to formulating and appraising drug policy: A multi-criterion decision analysis applied to alcohol and cannabis regulation.

scientific article published on 16 February 2018

A new human (psycho)pharmacology tool: the multiple organs coincidences counter (MOCC)

scientific article published on 01 January 1995

A pharmacodynamic study of the alpha 2-adrenergic receptor antagonist ethoxyidazoxan in healthy volunteers

scientific article published on 01 October 1994

A pilot controlled study of the effects of flumazenil in posttraumatic stress disorder

scientific article published in May 1997

A pilot study of the effect of short-term escitalopram treatment on brain metabolites and gamma-oscillations in healthy subjects

scientific article published in June 2016

A pilot study of the effectiveness of D-cycloserine during cue-exposure therapy in abstinent alcohol-dependent subjects

scientific article published on 12 February 2011

A pilot study on the effects of treatment with acamprosate on craving for alcohol in alcohol-dependent patients

scientific article

A placebo-controlled investigation of synaesthesia-like experiences under LSD.

scientific article published on 5 April 2016

A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability

scientific article published on October 2017

A proof-of-concept study using [11C]flumazenil PET to demonstrate that pagoclone is a partial agonist

scientific article

A proposal for an updated neuropsychopharmacological nomenclature

scientific article published on 18 September 2013

A psychopharmacological treatment algorithm for generalised anxiety disorder (GAD)

scientific article

A qualitative report on the subjective experience of intravenous psilocybin administered in an FMRI environment.

scientific article

A randomised trial of the effect of the glycine reuptake inhibitor Org 25935 on cognitive performance in healthy male volunteers.

scientific article published in March 2014

A review of the current nomenclature for psychotropic agents and an introduction to the Neuroscience-based Nomenclature

scientific article

A single dose of FG 7142 causes long-term increases in mouse cortical β-adrenoceptors

scientific article published on 01 February 1987

A single electroconvulsive shock substantially lowers blood glucose levels in obese mice (C57BL/6J ob/ob).

scientific article published on January 1988

A single preexposure produces sensitization to the locomotor effects of cocaine in mice

scientific article published in July 1993

A tale of two Es

scientific article published on 01 May 2006

A tale of two moralities: Politicians, doctors, use of addictive substances and lobbying

scholarly article

A technique for chronic catheterization of the cisterna magna in rabbits

scientific article published on 01 December 1988

A translational rodent assay of affective biases in depression and antidepressant therapy

scientific article published on 15 March 2013

A translational, caffeine-induced model of onset insomnia in rats and healthy volunteers

scientific article published on 16 January 2007

A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers

scientific article published on 13 March 2006

A web-based survey on mephedrone ⬇️

scientific article published on March 21, 2011

ADHD matures: time for practitioners to do the same?

scientific article published on 2 September 2011

Abstinence symptoms after withdrawal of tranquillising drugs: is there a common neurochemical mechanism?

scientific article published in August 1982

Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence

scientific article

Acute acetate administration increases endogenous opioid levels in the human brain: A [<sup>11</sup>C]carfentanil molecular imaging study

scientific article published on 06 January 2021

Acute and chronic effects of cannabinoids on effort-related decision-making and reward learning: an evaluation of the cannabis 'amotivational' hypotheses

scientific article

Acute and chronic effects of the benzodiazepine receptor ligand FG 7142: proconvulsant properties and kindling

scientific article published on December 1984

Acute and chronic idazoxan in normal volunteers: biochemical, physiological and psychological effects

scientific article published on 01 January 1991

Acute effects of MDMA on trust, cooperative behaviour and empathy: A double-blind, placebo-controlled experiment

scientific article published on 15 June 2020

Acute effects of cannabis on speech illusions and psychotic-like symptoms: two studies testing the moderating effects of cannabidiol and adolescence

scientific article published on 28 April 2020

Acute increases in synaptic GABA detectable in the living human brain: a [¹¹C]Ro15-4513 PET study

scientific article published on 17 May 2014

Acute naltrexone does not remediate fronto-striatal disturbances in alcoholic and alcoholic polysubstance-dependent populations during a monetary incentive delay task

scientific article published on 6 September 2016

Acute tryptophan depletion alters gastrointestinal and anxiety symptoms in irritable bowel syndrome

scientific article published on 4 October 2006

Acute tryptophan depletion. Part I: rationale and methodology

scientific article

Acute tryptophan depletion. Part II: clinical effects and implications

scientific article

Addiction and withdrawal—current views ⬇️

scientific article published on February 1, 2001

Addiction research and theory: a commentary on the Surgeon General's Report on alcohol, drugs, and health.

scientific article published on 21 February 2017

Addiction.

scientific article published in January 2003

Addiction: brain mechanisms and their treatment implications

scientific article published on January 1996

Addiction: lifestyle choice or medical diagnosis? ⬇️

scientific article published on June 1, 2013

Adenosine receptor subtypes modulate two major functional pathways for hippocampal serotonin release.

scientific article

Adult night terrors and paroxetine ⬇️

scientific article published on July 19, 1997

Adverse effects from antidepressant treatment: randomised controlled trial of 601 depressed individuals

scientific article

Aggressive thoughts and behavior: another symptom of panic disorder?

scientific article published in May 1989

Alcohol Hangover: Underlying Biochemical, Inflammatory and Neurochemical Mechanisms

scientific article published on 01 May 2019

Alcohol alternatives – a goal for psychopharmacology?

Alcohol alternatives--a goal for psychopharmacology?

scientific article

Alcohol and Relatively Pure Cannabis Use, but Not Schizotypy, are Associated with Cognitive Attenuations

scientific article

Alcohol and the Brain

Alcohol antagonists--the continuing quest

scientific article published on 01 August 1988

Alcohol: the drug

scientific article

Alcoholism and panic disorder: is the comorbidity more than coincidence?

scientific article published on February 1990

Alpha 2-adrenoceptor antagonists block the stimulant effects of cocaine in mice

scientific article published on January 1, 1992

Alpha-2-adrenoceptor control of cortisol and ACTH in normal volunteers: preliminary open trial of the effects of acute and chronic idazoxan.

scientific article

Alpha-2-adrenoceptor function in alcoholics

scientific article published on 01 January 1988

Alterations in white matter microstructure in alcohol and alcohol‐polydrug dependence: Associations with lifetime alcohol and nicotine exposure

Altered Insula Connectivity under MDMA.

scientific article published on 14 February 2017

Altered central alpha 2-adrenoceptor sensitivity in panic disorder

scientific article published in February 1989

Amphetamine induced endogenous opioid release in the human brain detected with [¹¹C]carfentanil PET: replication in an independent cohort

scientific article

Amphetamine misuse and social phobia

scientific article published on 01 May 2000

Amphetamine, past and present--a pharmacological and clinical perspective

scientific article

An unsquared circle: Biological Council Symposium on Experimental Approaches to Anxiety and Depression: Royal Institution, April 1991

scientific article published on 01 January 1991

Analysis of dynamic radioligand displacement or "activation" studies

scientific article published on 01 January 1997

Anhedonia and chronic mild stress model in depression ⬇️

scientific article published on 01 December 1997

Anhedonia revisited: is there a role for dopamine-targeting drugs for depression?

scientific article published on 31 July 2013

Antagonist-agonist combinations as therapies for heroin addiction: back to the future?

scientific article

Antagonizing the anticonvulsant effect of ethanol using drugs acting at the benzodiazepine/GABA receptor complex

scientific article published on 01 November 1988

Anti-oxidant vitamins and mental performance of the elderly

Anticonvulsant activity of the imidazoline 6,7-benzoidazoxan ⬇️

scientific article published on 01 July 1991

Antidepressant-induced jitteriness/anxiety syndrome: systematic review.

scientific article

Antidepressants in panic disorder: clinical and preclinical mechanisms

scientific article published on January 1, 1998

Antidepressants, withdrawal, and addiction; where are we now?

scientific article published on 21 May 2019

Antidepressants; what's the beef?

scientific article published on 01 February 2019

Antipsychotics, HERG and sudden death

scientific article published on 01 February 2003

Anxiety and OCD - the chicken or the egg?

scientific article published in November 2006

Anxiety and depression: individual entities or two sides of the same coin?

scientific article published in January 2004

Anxiety--bridging the heart/mind divide.

scientific article published on 03 April 2009

Anxiolytics

scientific article published on January 2012

Are 5-HT receptors or beta-adrenoceptors involved in idazoxan-induced food and water intake?

scientific article published on November 1, 1992

Are multiple physical symptoms a poor prognostic factor or just a marker of depression severity? Secondary analysis of the GenPod trial

scientific article

Arthritis and serotonergic antidepressants

scientific article published in August 2001

Assessing expectancy and suggestibility in a trial of escitalopram v. psilocybin for depression

scholarly article

Assessment and management of insomnia

scientific article published on 01 March 2005

Assessment of GABAA benzodiazepine receptor (GBzR) sensitivity in patients with alcohol dependence

scientific article published on 27 June 2008

Assessment of the quality of brain regions and neuroimaging metrics as biomarkers of Alzheimer's Disease

scientific article published on December 2015

Association of short alleles of a VNTR of the serotonin transporter gene with anxiety symptoms in patients presenting after deliberate self harm

scientific article published in April 1997

Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption

scientific article

Attacks on antidepressants: signs of deep-seated stigma?

scientific article published in July 2014

Attenuation of ethanol intoxication by alpha-2 adrenoceptor antagonists

scientific article published on 01 January 1989

Attenuation of the behavioural effects of ethanol in mice by des-enkephalin-gamma-endorphin (ORG 5878) ⬇️

scientific article published on 01 July 1992

Autonomic dysregulation and the Window of Tolerance model of the effects of complex emotional trauma

scientific article published on 21 January 2010

Autoradiographical and behavioural effects of a chronic infusion of antisense to the alpha2D-adrenoceptor in the rat.

scientific article

Autoradiographical distribution of imidazoline binding sites in monoamine oxidase A deficient mice

scientific article published on 10 February 2006

Autoradiography of I2 receptors in frog brain

scientific article

BAP Position Statement: Off-label prescribing of psychotropic medication to children and adolescents

scientific article published in May 2016

BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: recommendations from BAP.

scientific article

BRAIN SEROTONIN RELEASE IS REDUCED IN PATIENTS WITH DEPRESSION: A [11C]Cimbi-36 PET STUDY WITH A D-AMPHETAMINE CHALLENGE.

scientific article published in October 2022

BU98008, a highly selective imidazoline(1)-receptor ligand.

scientific article published in December 2003

Behavioral and cardiovascular effects of 7.5% CO2 in human volunteers.

scientific article published in January 2005

Behavioral and endocrine responses to clomipramine in panic disorder patients with or without alcoholism

scientific article published on 01 January 1995

Behavioral and neuroendocrine responses to m-chlorophenylpiperazine in subtypes of alcoholics and in healthy comparison subjects

scientific article published in January 1997

Behavioral, neuroendocrine and neurochemical effects of the imidazoline I2 receptor selective ligand BU224 in naive rats and rats exposed to the stress of the forced swim test

scientific article published on 22 March 2003

Behavioural and physiological effects induced by an infusion of antisense to alpha(2D)-adrenoceptors in the rat.

scientific article published in May 2000

Behavioural tasks sensitive to acute abstinence and predictive of smoking cessation success: a systematic review and meta-analysis

scientific article

Benzodiazepine dependence in the clinic: reason for anxiety?

scientific article (publication date: 1986)

Benzodiazepine receptor function in anxiety disorders

scientific article published on January 1, 1995

Benzodiazepine receptor sensitivity in panic disorder

scientific article published in March 1991

Benzodiazepine site pharmacokinetic/pharmacodynamic quantification in man: direct measurement of drug occupancy and effects on the human brain in vivo

scientific article published in January 1996

Benzodiazepine-receptor mediated convulsions in infant rats: effects of beta-carbolines

scientific article published on 01 April 1986

Benzodiazepine-serotonin interactions in man.

scientific article published in January 1987

Benzodiazepines: risks and benefits. A reconsideration

scientific article

Beyond psychoanaleptics - can we improve antidepressant drug nomenclature?

scientific article published in June 2009

Bidirectional effects of chronic treatment with agonists and inverse agonists at the benzodiazepine receptor

scientific article

Biological Markers of Generalized Anxiety Disorder

scientific article published on 27 April 2018

Biological markers for anxiety disorders, OCD and PTSD - a consensus statement. Part I: Neuroimaging and genetics

scientific article

Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition

scientific article published on 15 July 2016

Biological markers of generalized anxiety disorder

scientific article published on June 2017

Biological predictors of pharmacological therapy in anxiety disorders

scientific article

Blockade of alcohol's amnestic activity in humans by an alpha5 subtype benzodiazepine receptor inverse agonist

scientific article published on 16 August 2007

Blunted Endogenous Opioid Release Following an Oral Amphetamine Challenge in Pathological Gamblers

scientific article published on 10 November 2015

Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol-dependent individuals

scientific article published on 25 June 2018

Body temperature discriminates between full and partial benzodiazepine receptor agonists

scientific article published on 01 August 1990

Brain dopamine response in human opioid addiction.

scientific article

Brain function in social anxiety disorder ⬇️

scientific article published on December 1, 2001

Brain imaging studies in human addicts

scientific article published on December 2003

Brain mechanisms of social anxiety disorder.

scientific article published in January 1998

Brain opioid receptor binding in early abstinence from alcohol dependence and relationship to craving: an [11C]diprenorphine PET study.

scientific article

Brain opioid receptor binding in early abstinence from opioid dependence: positron emission tomography study.

scientific article

British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders.

scientific article

British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: An update

scientific article published on 04 July 2019

Broadband cortical desynchronization underlies the human psychedelic state

scientific article

Building bridges between neuroscientific evidence and policy

scientific article

Buprenorphine-cocaine interactions in mice: effect on locomotor activity and hole-dipping behaviour

scientific article published in July 1993

Buprenorphine/naloxone versus methadone and lofexidine in community stabilisation and detoxification: A randomised controlled trial of low dose short-term opiate-dependent individuals

scientific article published in June 2017

CNS drug development in Europe — Past progress and future challenges

scientific article published on 14 May 2013

Caffeine and central noradrenaline: effects on mood, cognitive performance, eye movements and cardiovascular function

scientific article published in September 2003

Can pragmatic research, real-world data and digital technologies aid the development of psychedelic medicine?

scientific article published in 2021

Canalization and plasticity in psychopathology

scientific article published in March 2023

Cannabis Dampens the Effects of Music in Brain Regions Sensitive to Reward and Emotion

scientific article published on 2 September 2017

Cannabis and opioid overdoses: time to move on and examine potential mechanisms

Cannabis antagonists: a new era of social psychopharmacology?

scientific article published in January 2005

Cape Town consensus on posttraumatic stress disorder

scientific article published on January 2009

Carbamazepine retards the development of cocaine-kindled seizures but not sensitization to cocaine-induced hyperactivity

scientific article (publication date: August 1990)

Cardiac slowing and acute tryptophan depletion: a comment on the paper by van der Veen et al.

scientific article

Care of depressed patients with anxiety symptoms.

scientific article

Central alpha-2 adrenoceptors are responsible for a clonidine-induced cue in a rat drug discrimination paradigm

scientific article published in January 1993

Central noradrenergic responsiveness to a clonidine challenge in Generalized Anxiety Disorder: a Single Photon Emission Computed Tomography study

scientific article published on 17 September 2011

Cerebral blood flow predicts differential neurotransmitter activity.

scientific article published on 6 March 2018

Cerebrospinal fluid monoamine metabolites in alcoholic patients who attempt suicide ⬇️

scientific article published on 01 January 1990

Challenge tests: assessment of the noradrenergic and GABA systems in depression and anxiety disorders

scientific article

Changes in benzodiazepine/GABA receptor complex function in benzodiazepine-tolerant mice

scientific article published on 01 January 1988

Changes in caffeine seizure threshold after electroconvulsive shock

scientific article published on January 1988

Changes in cardiovascular function after venlafaxine but not pregabalin in healthy volunteers: a double-blind, placebo-controlled study of orthostatic challenge, blood pressure and heart rate

scientific article published in November 2013

Changes in regional cerebral blood flow elicited by craving memories in abstinent opiate-dependent subjects

scientific article

Chapter 5.1 Phenomenology of anxiety disorders

Characterisation and localisation of [3H]2-(2-benzofuranyl)-2-imidazoline binding in rat brain: a selective ligand for imidazoline I2 receptors

scientific article published in July 1998

Characterisation of imidazoline I2 binding sites in pig brain

scientific article published in September 2005

Characterisation of the contribution of the GABA-benzodiazepine α1 receptor subtype to [(11)C]Ro15-4513 PET images

scientific article published on 4 January 2012

Characterisation of the effects of caffeine on sleep in the rat: a potential model of sleep disruption.

scientific article published on 24 April 2009

Characterization and autoradiographical localization of non-adrenoceptor idazoxan binding sites in the rat brain ⬇️

scientific article published on August 1, 1992

Characterization of [(3)H]harmane binding to rat whole brain membranes.

scientific article published in December 2003

Chest pain: panic attack or heart attack?

scientific article

Chronic benzodiazepine treatment increases the effects of the inverse agonist FG7142.

scientific article published in April 1988

Chronic electroconvulsive shock and neurotransmitter receptors--an update

scientific article

Clinical correlates of benzodiazepine receptor function

scientific article published on January 1, 1992

Clinical evidence and potential neurobiological underpinnings of unresolved symptoms of depression

scientific article published on February 2008

Clinical pharmacology of anxiolytics and antidepressants: a psychopharmacological perspective

scientific article published on January 1989

Clinical relevance of as-needed treatment with nalmefene in alcohol-dependent patients

scientific article

Cognition in schizophrenia: summary Nice Consultation Meeting 2012.

scientific article published on 15 May 2013

Cognitive processing in post-traumatic stress disorder

scientific article published in January 1996

Comparison of alterations in c-fos and Egr-1 (zif268) expression throughout the rat brain following acute administration of different classes of antidepressant compounds.

scientific article published in July 2005

Comparison of crude methanolic CDS extracts from various tissues

scientific article

Comparison of the effects of benzodiazepine and β-carboline inverse agonists on body temperature in mice ⬇️

scientific article published on November 26, 1991

Comparison of the effects of chronic desmethylimipramine administration on α2- and β-adrenoceptors in different regions of rat brain ⬇️

scientific article published on January 1, 1983

Comparison of the effects of repeated electroconvulsive shock on alpha 2- and beta-adrenoceptors in different regions of rat brain

scientific article published on 01 July 1982

Compound asset sharing initiatives between pharmaceutical companies, funding bodies, and academia: Learnings and successes

scientific article published on 30 July 2019

Concerns regarding conclusions made about LSD-treatments (received 25 October 2016).

scientific article

Consensus Statement on European Brain Research: the need to expand brain research in Europe - 2015.

scientific article published on 15 March 2016

Consensus statement and research needs: the role of dopamine and norepinephrine in depression and antidepressant treatment

scientific article published on 01 January 2006

Consensus statement on depression, anxiety, and cardiovascular disease.

scientific article

Consensus statement on depression, anxiety, and functional gastrointestinal disorders.

scientific article

Consensus statement on depression, anxiety, and oncology.

scientific article

Consensus statement on generalized anxiety disorder from the International Consensus Group on Depression and Anxiety.

scientific article published in January 2001

Consensus statement on panic disorder from the International Consensus Group on Depression and Anxiety

scientific article published on 01 January 1998

Consensus statement on posttraumatic stress disorder from the International Consensus Group on Depression and Anxiety

scientific article

Consensus statement on social anxiety disorder from the International Consensus Group on Depression and Anxiety

scientific article published in January 1998

Consensus statement on the benefit to the community of ESEMeD (European Study of the Epidemiology of Mental Disorders) survey data on depression and anxiety.

scientific article

Consensus statement on the primary care management of depression from the International Consensus Group on Depression and Anxiety

scientific article

Consensus statement on transcultural issues in depression and anxiety from the International Consensus Group on Depression and Anxiety.

scientific article

Consensus statement update on posttraumatic stress disorder from the international consensus group on depression and anxiety

scientific article

Considerations on the role of buprenorphine in recovery from heroin addiction from a UK perspective

scientific article

Correction to: Imaging and Genetic Approaches to Inform Biomarkers for Anxiety Disorders, Obsessive-Compulsive Disorders, and PSTD

scientific article published on 01 January 2018

Correction to: The hidden therapist: evidence for a central role of music in psychedelic therapy

scientific article published on 01 May 2018

Correction: DMT alters cortical travelling waves

scientific article published on 09 November 2020

Correlation of subjective and objective sleep measurements at different stages of the treatment of depression ⬇️

scientific article published on September 30, 2003

Crossover trial of pagoclone and placebo in patients with DSM-IV panic disorder

scientific article published in September 2001

Current and former ecstasy users report different sleep to matched controls: a web-based questionnaire study

scientific article published on 18 June 2008

Current research priorities in chronic fatigue syndrome/myalgic encephalomyelitis: disease mechanisms, a diagnostic test and specific treatments

scientific article

Cyproterone to treat aggressivity in dementia: a clinical case and systematic review

scientific article

Cytokine levels in euthymic bipolar patients

scientific article published on 01 November 2010

D-Cycloserine and performance under different states of anxiety in healthy volunteers.

scientific article published on 18 May 2007

DMT Models the Near-Death Experience

article by Christopher Timmermann et al published 15 August 2018 in Frontiers in Psychology

David Nutt: Champions off-licence prescribing

scientific article published on 27 May 2015

Death and dependence: current controversies over the selective serotonin reuptake inhibitors

scientific article published on December 2003

Death by tricyclic: the real antidepressant scandal?

scientific article

Deaths from "legal highs": a problem of definitions

scientific article published on 01 March 2014

Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study

scientific article

Decreased mental time travel to the past correlates with default-mode network disintegration under lysergic acid diethylamide

scientific article

Defining substance use disorders: do we really need more than heavy use?

scientific article published on 07 August 2013

Demonstration of clomipramine and venlafaxine occupation at serotonin reuptake sites in man in vivo

scientific article published in January 1997

Depleting Serotonin Enhances Both Cardiovascular and Psychological Stress Reactivity in Recovered Patients With Anxiety Disorders

scientific article published on 01 August 2006

Desipramine binding to noradrenaline reuptake sites in cardiac sympathetic neurons in man in vivo

scientific article published on 01 March 2000

Determination of [(11)C]PBR28 binding potential in vivo: a first human TSPO blocking study

scientific article

Determination of [11C]PBR28 binding potential in vivo: a first human TSPO blocking study.

scientific article published in July 2014

Development and validation of the Generalized Anxiety Disorder Inventory (GADI)

scientific article published in March 2007

Development of a rational scale to assess the harm of drugs of potential misuse

scientific article

Diazepam alters brain 5-HT function in man: implications for the acute and chronic effects of benzodiazepines.

scientific article published in August 1987

Diazepam and Ro 15-1788 increase absence epilepsy in WAG/Rij rats chronically exposed to diazepam

scientific article published in March 1990

Differences between magnetoencephalographic (MEG) spectral profiles of drugs acting on GABA at synaptic and extrasynaptic sites: a study in healthy volunteers

scientific article published on 4 September 2014

Differential effects of selective mu-, kappa- and delta-opioid antagonists on electroshock seizure threshold in mice

scientific article

Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 1, a pharmacokinetic/pharmacodynamic comparison with paroxetine in healthy men.

scientific article

Discontinuation of Vioxx

Discriminative stimulus produced by the imidazoline I2 site ligand, 2 -BFI ⬇️

scientific article published on January 1, 1996

Discriminative stimulus properties of ethoxy idazoxan ⬇️

scientific article published on 01 January 1995

Dissociable effects of cannabis with and without cannabidiol on the human brain's resting-state functional connectivity

scientific article published on 23 April 2019

Distinct Neuropsychological Mechanisms May Explain Delayed- Versus Rapid-Onset Antidepressant Efficacy

scientific article published on 5 March 2015

Distribution of [(3)H]BU224, a selective imidazoline I(2) binding site ligand, in rat brain

scientific article published in August 2002

Disturbances across whole brain networks during reward anticipation in an abstinent addiction population

scientific article published on 26 May 2020

Disturbances of hypothalamic-pituitary-adrenal axis functioning during ethanol withdrawal in six men.

scientific article published in August 1991

Dizziness produced by a potent 5HT(1A) receptor agonist (eptapirone) is not due to postural hypotension

scientific article published on 24 December 2004

Do Opioid, alpha(2)-Adrenoreceptors, or Benzodiazepine Receptors Mediate ECS-Induced Hypothermia in Mice?

scientific article

Do SSRIs prolong seizure duration during ECT?

scientific article published on 01 January 1997

Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine

scientific article

Does alcohol increase the risk of overdose death: the need for a translational approach

scientific article published on 7 April 2008

Does baseline fatigue influence treatment response to reboxetine or citalopram in depression? An open label randomized controlled trial

scientific article published on 4 January 2012

Does the Brain Noradrenaline Network Mediate the Effects of the CO2 Challenge? ⬇️

scientific article published on September 1, 2003

Doing it by numbers: a simple approach to reducing the harms of alcohol

scientific article

Don't panic. A guide to tryptophan depletion with disorder-specific anxiety provocation

scientific article published on 20 June 2016

Dopamine and social anxiety disorder ]]>

scientific article published on 01 December 2006

Dopamine transporter binding in females with panic disorder may vary with clinical status.

scientific article published on 24 May 2009

Dopaminergic challenges in social anxiety disorder: evidence for dopamine D3 desensitisation following successful treatment with serotonergic antidepressants.

scientific article published on 6 October 2008

Dr Shipman's last legacy: e-surveillance of the medical profession

scientific article published on 01 September 2005

Drug harms in the UK: a multicriteria decision analysis

scientific article

Dual function of the hydration layer around an antifreeze protein revealed by atomistic molecular dynamics simulations

scientific article published on 6 September 2008

Dynamical exploration of the repertoire of brain networks at rest is modulated by psilocybin

scientific article published on 25 May 2019

E-cigarettes are less harmful than smoking.

scientific article

ECNP Summit on the future of CNS drug research in Europe 2011: report prepared for ECNP by David Nutt and Guy Goodwin

scientific article published in July 2011

Editorial

Editorial

Editorial

article published in 1996

Effect of Single and Repeated Electroconvulsive Shock on Body Temperature in Mice

scientific article published on 01 January 1989

Effect of benzodiazepine and beta-carboline antagonists and partial agonists on loprazolam- and ZK 93423-induced hypothermia

scientific article published in February 1991

Effect of chloride or glucose on the incidence of lactate-induced panic attacks

scientific article published on 01 May 1995

Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans

Effect of pregnancy on panic attacks

scientific article published in August 1987

Effect of short-term escitalopram treatment on neural activation during emotional processing

scientific article published on 8 December 2015

Effect of single and repeated electroconvulsive shock on the hypothalamic-pituitary-adrenal axis and plasma catecholamines in rats

scientific article published on 01 January 1989

Effect of the cyclopyrrolones suriclone and RP 59037 on body temperature in mice

scientific article published on 01 May 1992

Effects of 5 weeks of administration of fluoxetine and dothiepin in normal volunteers on sleep, daytime sedation, psychomotor performance and mood.

scientific article

Effects of 7.5% CO(2) inhalation on allocation of spatial attention to facial cues of emotional expression

scientific article

Effects of 7.5% CO2 challenge in generalized anxiety disorder

scientific article published on 16 March 2010

Effects of 7.5% CO2-Induced Anxiety on Individual Performance During a Group Computer Combat Game

article published in 2013

Effects of DMT on mental health outcomes in healthy volunteers

scholarly article

Effects of External Stimulation on Psychedelic State Neurodynamics

scholarly article published on 12 January 2024

Effects of Schedule I drug laws on neuroscience research and treatment innovation

scientific article published on 12 June 2013

Effects of acute and chronic electroconvulsive shock on noradrenaline release in the rat hippocampus and frontal cortex ⬇️

scientific article published on June 1, 1992

Effects of acute tryptophan depletion in serotonin reuptake inhibitor-remitted patients with generalized anxiety disorder.

scientific article published on 21 November 2009

Effects of acute tyrosine/phenylalanine depletion on the selective processing of smoking-related cues and the relative value of cigarettes in smokers

scientific article published on 25 November 2007

Effects of benzodiazepine receptor inverse agonists on locomotor activity and exploration in mice

scientific article published on October 20, 1992

Effects of bupropion augmentation in escitalopram-resistant patients with major depressive disorder: an open-label, naturalistic study.

scientific article published in July 2009

Effects of chronic treatment with benzodiazepine receptor ligands on cortical adrenoceptors

scientific article

Effects of chronic α2-adrenoceptor blockade on platelet and lymphocyte adrenoceptor binding in normal volunteers ⬇️

scientific article published on 01 January 1991

Effects of naltrexone are influenced by childhood adversity during negative emotional processing in addiction recovery

scientific article

Effects of psilocybin therapy on personality structure

Effects of stressful life events, maternal depression and 5-HTTLPR genotype on emotional symptoms in pre-adolescent children

scientific article

Effects of the Common Cold on Subjective Alertness, Reaction Time, and Eye Movements

Effects of upper respiratory tract illnesses, ibuprofen and caffeine on reaction time and alertness

scientific article published on 28 November 2013

Effects on sleep architecture of pindolol, paroxetine and their combination in healthy volunteers

scientific article published on 21 January 2003

Effects on sleep stages and microarchitecture of caffeine and its combination with zolpidem or trazodone in healthy volunteers.

scientific article published on 7 April 2009

Efficacy and safety of sodium oxybate in alcohol-dependent patients with a very high drinking risk level

scientific article published on 01 July 2018

Efficacy of mirtazapine in clinically relevant subgroups of depressed patients ⬇️

scientific article published on January 1, 1998

Ego-Dissolution and Psychedelics: Validation of the Ego-Dissolution Inventory (EDI)

scientific article published on 14 June 2016

Electroconvulsive Shock Does Not Increase Plasma Insulin in Rats

scientific article published on 01 January 1988

Electroconvulsive shock (ECS) and the adenosine neuromodulatory system: effect of single and repeated ECS on the adenosine A1 and A2 receptors, adenylate cyclase, and the adenosine uptake site

scientific article published on February 1989

Elevating endogenous GABA levels with GAT-1 blockade modulates evoked but not induced responses in human visual cortex

scientific article published on 9 January 2013

Elucidation of neurobiology of anxiety disorders in children through pharmacological challenge tests and cortisol measurements: a systematic review

scientific article published on 19 July 2010

Emotional symptoms in children: The effect of maternal depression, life events, and COMT genotype

scientific article published on March 2009

Enantioselective intramolecular michael addition of nitronates onto conjugated esters: access to cyclic gamma-amino acids with up to three stereocenters

scientific article published in November 2009

Endocrine response to syncope in panic disorder

scientific article published in June 1989

Endogenous beta-carbolines as clonidine-displacing substances

scientific article published on December 2003

Endogenous indoleamines demonstrate moderate affinity for I2 binding sites

scientific article

Endogenous opioid release in the human brain reward system induced by acute amphetamine administration

scientific article

Endogenous opioids may be involved in idazoxan-induced food intake

scientific article published on August 1, 1992

Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions--I. The effects of single and repeated bicuculline-induced seizures

scientific article published on 01 September 1980

Enhanced 5-hydroxytryptamine and dopamine-mediated behavioural responses following convulsions--II. The effects of anaesthesia and current conditions on the appearance of enhanced responses following electroconvulsive shock

scientific article published in September 1980

Enhanced repertoire of brain dynamical states during the psychedelic experience. ⬇️

scientific article published on 3 July 2014

Equasy — An overlooked addiction with implications for the current debate on drug harms

scientific article published in January 2009

Equivalent effects of acute tryptophan depletion on REM sleep in ecstasy users and controls.

scientific article published on 8 July 2009

Erratum: Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence

correction of an scholarly article

Erratum: Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence

correction of a scholarly article

Estimating the harms of nicotine-containing products using the MCDA approach

scientific article (publication date: 2014)

Estimating the synaptic concentration of norepinephrine in dentate gyrus which produces beta-receptor mediated long-lasting potentiation in vivo using microdialysis and intracerebroventricular norepinephrine.

scientific article published on February 1996

Estimation of endogenous noradrenaline release in rat brain in vivo using [3H]RX 821002.

scientific article published in February 2005

Ethyl beta-carboline carboxylate lowers seizure threshold and antagonizes flurazepam-induced sedation in rats.

scientific article

European rating of drug harms

scientific article published on 28 April 2015

Evaluation and initial in vitro and ex vivo characterization of the potential positron emission tomography ligand, BU99008 (2-(4,5-dihydro-1H-imidazol-2-yl)-1- methyl-1H-indole), for the imidazoline₂ binding site

scientific article published on 22 February 2012

Evaluation in rat of RS-79948-197 as a potential PET ligand for central alpha 2-adrenoceptors.

scientific article published in December 1996

Evaluation of 11C-BU99008, a PET ligand for the imidazoline2 binding sites in rhesus brain

scientific article published on 7 April 2014

Evaluation of 11C-BU99008, a positron emission tomography ligand for the Imidazoline2 binding site in human brain.

scientific article published on 9 March 2018

Evaluation of [O-methyl-11C]RS-15385-197 as a positron emission tomography radioligand for central alpha2-adrenoceptors

scientific article published in May 2000

Evaluation of actigraphy and automated telephoned questionnaires to assess hypnotic effects in insomnia

scientific article published on March 2004

Evaluation of an operant successive negative contrast task as a method to study affective state in rodents.

scientific article published on 23 June 2012

Evaluation of severe insomnia in the general population--implications for the management of insomnia: the UK perspective

scientific article

Evaluation of severe insomnia in the general population: results of a European multinational survey

scientific article

Evaluation of the effects of venlafaxine and pregabalin on the carbon dioxide inhalation models of Generalised Anxiety Disorder and panic

scientific article published on 19 April 2012

Evidence for GABA-A receptor dysregulation in gambling disorder: correlation with impulsivity

scientific article published on 13 October 2016

Evidence for serotonin function as a neurochemical difference between fear and anxiety disorders in humans?

scientific article

Evidence-based guidelines for management of attention-deficit/hyperactivity disorder in adolescents in transition to adult services and in adults: recommendations from the British Association for Psychopharmacology

scientific article published on 8 November 2006

Evidence-based guidelines for the pharmacological management of attention deficit hyperactivity disorder: update on recommendations from the British Association for Psychopharmacology

scientific article published on 12 February 2014

Evidence-based guidelines for the pharmacological management of substance misuse, addiction and comorbidity: recommendations from the British Association for Psychopharmacology

scientific article published in September 2004

Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology

scientific article

Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 1993 British Association for Psychopharmacology guidelines. British Association for Psychopharmacology

scientific article

Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: a revision of the 2005 guidelines from the British Association for Psychopharmacology

scientific article

Experienced drug users assess the relative harms and benefits of drugs: a web-based survey

scientific article

Exploring delta-receptor function using the selective opioid antagonist naltrindole

scientific article published in December 1989

Exploring the pharmacology of the pro-convulsant effects of alpha 2-adrenoceptor antagonists in mice

scientific article published on 01 January 1991

Extraction of active clonidine-displacing substance from bovine lung and comparison with clonidine-displacing substance extracted from other tissues

scientific article published in August 1999

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

scientific article

Finding the self by losing the self: Neural correlates of ego-dissolution under psilocybin

scientific article

First evaluation of PET-based human biodistribution and radiation dosimetry of 11C-BU99008, a tracer for imaging the imidazoline2 binding site

scientific article published on 30 July 2018

First study of safety and tolerability of 3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy in patients with alcohol use disorder: preliminary data on the first four participants

scientific article published on 15 July 2019

Flumazenil as an anti-epileptic agent ⬇️

scientific article published on March 23, 1991

Flumazenil challenge in social phobia

scientific article

Flumazenil provocation of panic attacks. Evidence for altered benzodiazepine receptor sensitivity in panic disorder

scientific article

Foresight brain science, addiction and drugs project

scientific article published in July 2005

Functional connectivity analysis of the neural circuits of opiate craving: "more" rather than "different"?

scientific article

Functional connectivity measures after psilocybin inform a novel hypothesis of early psychosis

scientific article published on 08 October 2012

Functional evaluation of NK antagonism on cue reactivity in opiate dependence; An fMRI study

Functional studies of specific imidazoline-2 receptor ligands.

scientific article

GABA system dysfunction in autism and related disorders: from synapse to symptoms

scientific article published on 25 July 2012

GABA&lt;SUB&gt;A&lt;/SUB&gt; Receptors: Subtypes, Regional Distribution, and Function ⬇️

scholarly article

GABA-A receptor differences in schizophrenia: a positron emission tomography study using [11C]Ro154513

scientific article published on 15 April 2020

GABA-A receptors and the response to CO(2) inhalation - a translational trans-species model of anxiety?

scientific article published on 09 April 2008

GABA-benzodiazepine receptor function in alcohol dependence: a combined 11C-flumazenil PET and pharmacodynamic study

scientific article published on 28 April 2005

GABAA receptor availability is not altered in adults with autism spectrum disorder or in mouse models

article

GABAA receptors: subtypes, regional distribution, and function.

scientific article

GABAAbenzodiazepine receptor (GBzR) sensitivity: test-retest reliability in normal volunteers

scientific article published on 01 June 2000

GABAB receptors in addiction and its treatment

scientific article published on January 2010

GABAergic control of novelty stress-responsive epigenetic and gene expression mechanisms in the rat dentate gyrus.

scientific article published in April 2011

GENetic and clinical predictors of treatment response in depression: the GenPod randomised trial protocol

scientific article published on 22 May 2008

Gamma hydroxy butyrate abuse and dependency

scientific article

Gender differences in brain serotonin transporter availability in panic disorder

scientific article published on 8 December 2010

Gene expression subtypes in patients with chronic fatigue syndrome/myalgic encephalomyelitis.

scientific article published in April 2008

Gene-Tailored Treatments for Brain Disorders: Challenges and Opportunities

scientific article published on June 2016

Generalized anxiety disorder: A comorbid disease

scientific article published on 5 June 2006

Generalized anxiety disorder: comorbidity, comparative biology and treatment

scientific article

Generic legislation of new psychoactive drugs

scientific article

Glutamate and cortisol--a critical confluence in PTSD?

scientific article published in July 2008

Government vs science over drug and alcohol policy

scientific article

Harmane and harmalan are bioactive components of classical clonidine-displacing substance.

scientific article published in December 2004

Harmane: an atypical neurotransmitter?

scientific article published on 24 January 2015

Harms associated with psychoactive substances: findings of the UK National Drug Survey

scientific article published on 25 November 2009

Help luck along to find psychiatric medicines

scientific article

Hemispheric language asymmetry in first episode psychosis and schizotypy: the role of cannabis consumption and cognitive disorganization

scientific article

Highlights of the International Consensus Statement on Major Depressive Disorder

scientific article published on June 1, 2011

History of cannabis use is not associated with alterations in striatal dopamine D2/D3 receptor availability

scientific article published on 2 September 2011

History of cigarette smoking is associated with higher limbic GABAA receptor availability

scientific article published on 14 December 2012

Home cage presentation of complex discrimination tasks to marmosets and rhesus monkeys

scientific article published on 01 July 1999

Human functional neuroimaging connectivity research in dependence

scientific article

Human taste thresholds are modulated by serotonin and noradrenaline.

scientific article published in December 2006

Hypophysectomy alters both 5-hydroxytryptamine- and α2-adrenoceptor-mediated behavioural changes in the rat ⬇️

scientific article published on April 22, 1983

Hypophysectomy does not prevent the enhanced monoamine-mediated behavioural responses following repeated electroconvulsive shocks

scientific article published on 01 September 1982

Hypothermic responses to infection are inhibited by alpha2-adrenoceptor agonists with possible clinical implications

scientific article published on 23 July 2009

Idazoxan-induced reductions in cortical glucose use are accompanied by an increase in noradrenaline release: complementary [14C]2-deoxyglucose and microdialysis studies

scientific article published on 01 June 1995

Identification of an I(2) binding protein from rabbit brain

scientific article published in December 2003

Identification of an imidazoline binding protein: creatine kinase and an imidazoline-2 binding site

scientific article published on 03 May 2009

Identification of ligands selective for central I2-imidazoline binding sites

scientific article published on 01 January 1997

Illegal drugs laws: clearing a 50-year-old obstacle to research

scientific article

Imaging alcohol cue exposure in alcohol dependence using a PET 15O-H2O paradigm: results from a pilot study

scientific article published on March 2006

Imaging and Genetic Approaches to Inform Biomarkers for Anxiety Disorders, Obsessive-Compulsive Disorders, and PSTD.

scientific article published on 24 May 2018

Imaging endogenous opioid peptide release with [11C]carfentanil and [3H]diprenorphine: influence of agonist-induced internalization

scientific article published on 9 July 2014

Imaging imidazoline-I2 binding sites in porcine brain using 11C-BU99008.

scientific article

Imaging the GABA-benzodiazepine receptor subtype containing the alpha5-subunit in vivo with [11C]Ro15 4513 positron emission tomography

scientific article

Imidazoline 2 binding sites reflecting astroglia pathology in Parkinson's disease: an in vivo11C-BU99008 PET study

scientific article published on 01 October 2019

Imidazoline binding sites in Huntington's and Parkinson's disease putamen

scientific article published in April 1996

Imidazoline ligand BU224 reverses cognitive deficits, reduces microgliosis and enhances synaptic connectivity in a mouse model of Alzheimer's disease

scientific article published on 03 November 2020

Imidazoline(2) (I(2)) binding site- and alpha(2)-adrenoceptor-mediated modulation of central noradrenergic and HPA axis function in control rats and chronically stressed rats with adjuvant-induced arthritis

scientific article

Imidazoline2 (I2) receptor- and alpha2-adrenoceptor-mediated modulation of hypothalamic-pituitary-adrenal axis activity in control and acute restraint stressed rats

scientific article published in March 2004

Imipramine in panic disorder. 1. Clinical response and pharmacological changes ⬇️

scientific article published on 01 January 1991

Imipramine in panic disorder. 2. Effects on α2-adrenoceptor function ⬇️

scientific article published on 01 January 1991

Implications for psychedelic-assisted psychotherapy: functional magnetic resonance imaging study with psilocybin.

scientific article published on 26 January 2012

Impulsivity in abstinent alcohol and polydrug dependence: a multidimensional approach

scientific article published on 25 February 2016

In vitro and ex vivo distribution of [3H]harmane, an endogenous beta-carboline, in rat brain

scientific article published on 19 October 2005

In vitro and in vivo approaches to the characterization of the alpha2-adrenoceptor

scientific article published on December 1999

In vitro and in vivo effect of BU99006 (5-isothiocyanato-2-benzofuranyl-2-imidazoline) on I2 binding in relation to MAO: evidence for two distinct I2 binding sites

scientific article published on 10 October 2006

In vivo estimation of imidazoline(2) binding site turnover.

scientific article published in December 2003

In vivo imaging of cerebral dopamine D3 receptors in alcoholism.

scientific article

In vivo imaging of microglial activation by positron emission tomography with [(11)C]PBR28 in the 5XFAD model of Alzheimer's disease

scientific article

Increased Global Functional Connectivity Correlates with LSD-Induced Ego Dissolution

scientific article published on 11 April 2016

Increased amygdala responses to emotional faces after psilocybin for treatment-resistant depression

scientific article published on 27 December 2017

Increased central alpha 2-adrenoceptor sensitivity in panic disorder

scientific article

Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome ⬇️

scientific article published on October 1, 2010

Increased sympathetic response to standing in panic disorder

scientific article published in May 2003

Infecting the brain to stop addiction?

scholarly article

Influence of agonist induced internalization on [3H]Ro15-4513 binding-an application to imaging fluctuations in endogenous GABA with positron emission tomography

scientific article published on 19 September 2014

Influence of different cellular environments on [(3)H]DASB radioligand binding

scientific article published on 20 September 2012

Informed consent--a new approach to drug regulation?

scientific article published on 01 January 2006

Inhalation of 35% CO(2) results in activation of the HPA axis in healthy volunteers

scientific article published in August 2002

Inhibition of baolofen-induced hypothermia in mice by the novel GABAB antagonist CGP 35348 ⬇️

scientific article published on May 1, 1991

Inhibition of central monoamine oxidase by imidazoline2 site-selective ligands

scientific article

Initial evaluation of novel selective ligands for imidazoline(2) receptors in rat whole brain.

scientific article published in December 2003

Innovative solutions to novel drug development in mental health

scientific article (publication date: December 2013)

Integrating the cognitive and physiological aspects of craving ⬇️

scientific article published on January 1, 1998

Interactions between classic psychedelics and serotonergic antidepressants: Effects on the acute psychedelic subjective experience, well-being and depressive symptoms from a prospective survey study

scholarly article

Interactions of the imidazodiazepine Ro 15-4513 with chemical convulsants

scientific article published on January 1988

International consensus statement on major depressive disorder

scientific article published on January 2010

Intrinsic actions of benzodiazepine antagonists ⬇️

scientific article published on October 8, 1982

Introduction to the 2016 Consensus Document on European Brain Research

scientific article published on 6 June 2016

Introduction. The neurobiology of drug addiction: new vistas

scientific article

Inverse agonists - What do they mean for psychiatry?

scientific article

Investigating benzodiazepine receptor function in vivo using an intravenous infusion of DMCM

scientific article published on 01 August 1984

Investigating expectation and reward in human opioid addiction with [(11) C]raclopride PET

scientific article

Investigation of the Different Types of Opioid Receptor Involved in Electroconvulsive Shock-induced Antinociception and Catalepsy in the Rat ⬇️

scientific article published on September 1, 1991

Investigation of the affinities of two new beta-carbolines for rat brain imidazoline(2) receptors

scientific article published in December 2003

Investigation of the involvement of opioid receptors in the action of anticonvulsants

scientific article published on January 1993

Investigation of the sleep electrocorticogram of the common marmoset (Callithrix jacchus) using radiotelemetry ⬇️

scientific article published on December 1, 2001

Investigations on the "set-point" theory of benzodiazepine receptor function

scientific article

Invited review: the evolution of antidepressant mechanisms

scientific article (publication date: February 2004)

Involvement of μ-opioid receptors in electroconvulsive shock-induced antinociception in the rat ⬇️

scientific article published on January 1, 1991

Is the UK's 2017 drug strategy fit for purpose?

scientific article published on 29 September 2017

Is the association of hypertension and panic disorder explained by clustering of autonomic panic symptoms in hypertensive patients?

scientific article published on 29 April 2008

Is there cognitive impairment in clinically 'healthy' abstinent alcohol dependence?

scientific article published on 26 September 2005

Isolation of RP-HPLC pure clonidine-displacing substance from NG108-15 cells

scientific article

Ketamine treatment for depression: opportunities for clinical innovation and ethical foresight.

scientific article published on 5 April 2017

Ketamine--the real perspective

scientific article published on 11 March 2016

Kindling and withdrawal changes at the benzodiazepine receptor

scientific article published on 01 January 1987

L-Tryptophan and prolactin release: Evidence for interaction between 5-HT1 and 5-HT2 receptors

article

LSD alters eyes-closed functional connectivity within the early visual cortex in a retinotopic fashion

scientific article

LSD enhances suggestibility in healthy volunteers

scientific article published on 23 September 2014

LSD enhances the emotional response to music.

scientific article

LSD modulates effective connectivity and neural adaptation mechanisms in an auditory oddball paradigm

scientific article published on 31 October 2017

LSD modulates music-induced imagery via changes in parahippocampal connectivity.

scientific article

LSD-induced entropic brain activity predicts subsequent personality change.

scientific article

Lactate and hyperventilation substantially attenuate vagal tone in normal volunteers. A possible mechanism of panic provocation?

scientific article published on February 1989

Lactate-induced electrolyte changes in the cerebrospinal fluid of rabbits

scientific article

Lamotrigine for attention deficit-hyperactivity disorder comorbid with mood disorders: a case series

scientific article

Legal highs: a problem of definitions? - Authors' reply

scientific article published on 01 May 2014

Let not the best be the enemy of the good ⬇️

scientific article published on September 6, 2011

Lithium treatment effect on serotonin function

scientific article published in March 1990

Long-term treatment strategies in anxiety disorders

scientific article

Low affinity hypothalamic [3H]mazindol binding: a probe for hypothalamic body weight regulation?

scientific article published on April 1989

Low sensitivity of the positron emission tomography ligand [11C]diprenorphine to agonist opiates

scientific article

Low serotonergic tone and elevated risk for substance misuse ⬇️

scientific article published on November 1, 2011

MDMA, politics and medical research: have we thrown the baby out with the bathwater?

scientific article published in November 2007

Maintenance buprenorphine for opioid users

scientific article published in February 2003

Making a medicine out of MDMA.

scientific article published in January 2015

Making sense of GABA(A) receptor subtypes: is a new nomenclature needed?

scientific article published in May 2005

Management of insomnia: treatments and mechanismsi

scientific article published in September 2007

Management of panic disorder in primary care

Manifesto for a European anxiety disorders research network

scientific article published on 30 March 2010

Massive overuse or appropriate medical intervention? The modern-day use of antidepressants ⬇️

scientific article published on January 28, 2012

Measuring endogenous 5-HT release by emission tomography: promises and pitfalls

scientific article published on 28 July 2010

Measuring the serotonin uptake site using [3H]paroxetine--a new serotonin uptake inhibitor

scientific article

Mechanism of action of antidepressants.

scientific article

Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse.

scientific article

Mechanisms of action of selective serotonin reuptake inhibitors in the treatment of psychiatric disorders

scientific article

Medical cannabis in the UK: From principle to practice

scientific article published on 10 June 2020

Membrane Permeation of Psychedelic Tryptamines by Dynamic Simulations

scholarly article

Mice and rats are sensitized to the proconvulsant action of a benzodiazepine-receptor inverse agonist (FG 7142) following a single dose of lorazepam

scientific article published in August 1986

Microbial infections in eight genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis

scientific article

Microdosing psychedelics: More questions than answers? An overview and suggestions for future research ⬇️

scientific article published on 14 July 2019

Mind-altering drugs and research: from presumptive prejudice to a Neuroscientific Enlightenment?: Science & Society series on "Drugs and Science"

scientific article published on 14 February 2014

Mirtazapine induces REM sleep behavior disorder (RBD) in parkinsonism

scientific article published in October 2003

Moclobemide in the treatment of social phobia

Monoamine function in anxiety and depression: Information from neuroendocrine challenge tests

Mourning and melancholia revisited: correspondences between principles of Freudian metapsychology and empirical findings in neuropsychiatry

scientific article

N1'-fluoroethyl-naltrindole (BU97001) and N1'-fluoroethyl-(14-formylamino)-naltrindole (BU97018) potential delta-opioid receptor PET ligands

scientific article published in May 2002

NAPSAQ-1: National Patient Sleep Assessment Questionnaire in depression

scientific article published in January 2009

NHS drug budget. Flawed assumption in analysis

scientific article published on 01 February 2011

NICE: The National Institute of Clinical Excellence -- or Eccentricity? Reflections on the Z-drugs as hypnotics

scientific article

Nalmefene Reduces Reward Anticipation in Alcohol Dependence: An Experimental Functional Magnetic Resonance Imaging Study.

scientific article

Naloxone displacement at opioid receptor sites measured in vivo in the human brain

scientific article published in January 2003

Naltrexone ameliorates functional network abnormalities in alcohol-dependent individuals

scientific article

Naltrexone differentially modulates the neural correlates of motor impulse control in abstinent alcohol-dependent and poly-substance dependent individuals

scientific article published on 26 November 2018

Natural speech algorithm applied to baseline interview data can predict which patients will respond to psilocybin for treatment-resistant depression

scientific article

Neural correlates of the DMT experience assessed with multivariate EEG

scientific article published on 19 November 2019

Neural correlates of the LSD experience revealed by multimodal neuroimaging

scientific article

Neural correlates of the psychedelic state as determined by fMRI studies with psilocybin

scientific article

Neural substrates of cue reactivity and craving in gambling disorder

scientific article published on 3 January 2017

Neurobiological mechanisms in generalized anxiety disorder

scientific article

Neurobiology of addiction and implications for treatment

scientific article

Neurochemical binding profiles of novel indole and benzofuran MDMA analogues

scientific article published on 20 September 2016

Neuroendocrine and clinical effects of electroconvulsive therapy and their relationship to treatment outcome

scientific article published on 01 August 1994

Neuroimaging of serotonin system in anxiety disorders

scientific article published on January 2012

Neuropharmacological Aspects of ECT: In Search of the Primary Mechanism of Action

scientific article published on 01 January 1989

Neuropharmacological and clinical aspects of alcohol withdrawal

scientific article published on January 1990

Neuropsychopharmacology across brain diseases

scientific article

Neuroreceptor science: a clarification of terms

scientific article published on 01 December 1988

Neuroscience in recession?

scientific article published in May 2011

Neuroscience-based Nomenclature (NbN) for Journal of Psychopharmacology

scientific article published in May 2016

New ACMD regulations threaten UK's pharmaceutical discovery

scientific article published in June 2017

New insights into the role of the GABAA–benzodiazepine receptor in psychiatric disorder ⬇️

scientific article published on November 1, 2001

New psychoactive substances: Pharmacology influencing UK practice, policy and the law

scientific article published on 04 February 2020

New victims of current drug laws

scientific article published on 23 October 2013

No psychiatry without psychopharmacology.

scientific article published in October 2011

Noradrenaline in depression: half a century of progress

scientific article published on 01 January 1997

Noradrenergic function in generalized anxiety disorder: impact of treatment with venlafaxine on the physiological and psychological responses to clonidine challenge

article

Noradrenergic mechanisms appear not to be involved in cocaine-induced seizures and lethality

scientific article (publication date: 1990)

Noradrenergic mechanisms in the prefrontal cortex

scientific article published on January 1997

Novel ligands for the investigation of imidazoline receptors and their binding proteins.

scientific article published in December 2003

Novel selective compounds for the investigation of imidazoline receptors

scientific article

Nutt damage – Author's reply

scientific article published in The Lancet

On assessing potential efficacy for vortioxetine in generalized anxiety disorder

scientific article published on 17 August 2012

On the convulsant action of Ro 5-4864 and the existence of a micromolar benzodiazepine binding site in rat brain

scientific article

On the measurement in rats of the convulsant effect of drugs and the changes which follow electroconvulsive shock

scientific article published on 01 October 1980

On the role of GABA in anxiety and depression

scientific article published in July 2004

Open letter from UK based academic scientists to the secretaries of state for digital, culture, media and sport and for health and social care regarding the need for independent funding for the prevention and treatment of gambling harms

scientific article published on 01 July 2020

Opiate agonists and antagonists modulate taste perception in opiate-maintained and recently detoxified subjects

scientific article published on 29 January 2013

Opioids and anxiety.

scientific article published on 08 June 2010

Optimising PET approaches to measuring 5-HT release in human brain

scientific article published on 19 June 2015

Optimizing the pentetrazol infusion test for seizure threshold measurement

scientific article

Orexin-A infusion in the locus ceruleus triggers norepinephrine (NE) release and NE-induced long-term potentiation in the dentate gyrus.

scientific article

Overview of diagnosis and drug treatments of anxiety disorders

scientific article

Oxytocin and vasopressin responses to ECT

scientific article published on 01 May 1990

P.609 Therapeutic mechanisms of psychedelic drugs: Changes in amygdala and prefrontal functional connectivity during emotional processing after psilocybin for treatment-resistant depression ⬇️

scholarly article

P.8.a.026 Pharmacokinetics of (S)-zopiclone and (S)-desmethylzopiclone following dosing with zopiclone and eszopiclone

PM298. Dissociable effects of cannabinoids on anticipatory and consummatory reward processing.

scientific article published on 27 May 2016

Panic and hypertension: brothers in arms through 5-HT?

scientific article published in August 2007

Panic attacks and alcohol withdrawal: can subjects differentiate the symptoms?

scientific article published in June 1988

Panic attacks are more likely to include autonomic symptoms in patients with hypertension than in normotensives — a comparison of symptoms, and factor analysis

Panic response to lactate administration in alcoholic and nonalcoholic patients with panic disorder

scientific article published in September 1989

Patient access. How to wipe out a growing killer.

scientific article published in October 2011

Personalized risk assessment of drug-related harm is associated with health outcomes

scientific article (publication date: 2013)

Perverse effects of the precautionary principle: how banning mephedrone has unexpected implications for pharmaceutical discovery

scientific article

Pharmacoendocrine studies in anxiety

scientific article published on January 1, 1992

Pharmacokinetics for psychiatrists

Pharmacokinetics for psychiatrists

Pharmacological and behavioural studies of benzodiazepine antagonists and contragonists

scientific article published on January 1, 1983

Pharmacological characterisation of novel alpha 2-adrenoceptor antagonists as potential brain imaging agents.

scientific article published in May 2004

Pharmacological cognitive enhancement in healthy people: potential and concerns

scientific article published on January 2013

Pharmacological mechanisms of benzodiazepine withdrawal

scientific article published on January 1990

Pharmacology of saccadic eye movements in man. 1. Effects of the benzodiazepine receptor ligands midazolam and flumazenil

scientific article published in January 1991

Pharmacology of saccadic eye movements in man. 2. Effects of the alpha 2-adrenoceptor ligands idazoxan and clonidine

scientific article published on 01 January 1991

Pharmacology should be at the centre of all preclinical and clinical studies on new psychoactive substances (recreational drugs).

scientific article

Pharmacotherapy of anxiety.

scientific article published on January 2005

Pindolol augmentation of sertraline in resistant depression and its effect on sleep ⬇️

scientific article published on January 1, 1998

Platelet alpha 2-adrenoceptor binding does not predict brain alpha 2-adrenoceptor function

scientific article

Platelet binding studies in panic disorder

scientific article published in January 1987

Polymorphism of the 5-HT transporter and response to antidepressants: randomised controlled trial

scientific article

Popular intoxicants: what lessons can be learned from the last 40 years of alcohol and cannabis regulation?

scientific article published on 17 September 2011

Potentiation of barbiturate-induced alterations in presynaptic noradrenergic function in rat frontal cortex by imidazol(in)e alpha2-adrenoceptor agonists.

scientific article published in October 1998

Predicting Responses to Psychedelics: A Prospective Study

article

Preliminary evidence of anxiolytic effects of the CRF(1) receptor antagonist R317573 in the 7.5% CO(2) proof-of-concept experimental model of human anxiety

scientific article

Preparation, structure and affinity for imidazoline I2 receptors and alpha2-adrenoceptors of 1-[(4,5-dihydroimidazolidin-2-yl)imino]indan-2-ols

scientific article published in November 2005

Prescribing antidepressants post Cipriani et al

scientific article published on 01 November 2009

Probes for imidazoline binding sites: synthesis and evaluation of a selective, irreversible I2 ligand

scientific article published on 01 March 2000

Progress in mind: focus on alcohol use disorders, an elsevier resource centre.

scientific article published on 25 February 2015

Psilocybin and MDMA reduce costly punishment in the Ultimatum Game.

scientific article published on 29 May 2018

Psilocybin for anxiety and depression in cancer care? Lessons from the past and prospects for the future

scientific article published in December 2016

Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms

scientific article published on 13 October 2017

Psilocybin lacks antidepressant-like effect in the Flinders Sensitive Line rat

scientific article published on 20 May 2019

Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study

scientific article (publication date: July 2016)

Psilocybin with psychological support for treatment-resistant depression: six-month follow-up.

scientific article published on 8 November 2017

Psilocybin with psychological support improves emotional face recognition in treatment-resistant depression.

scientific article

Psychedelic Psychiatry's Brave New World

scientific article published on 01 April 2020

Psychedelic experience dose-dependently modulated by cannabis: results of a prospective online survey

scientific article published on 04 November 2021

Psychedelics - Re-opening the doors of perception

scientific article published on 23 August 2018

Psychedelics and related drugs: therapeutic possibilities, mechanisms and regulation

scientific article published in February 2018

Psychedelics and sexual functioning: a mixed-methods study

scholarly article

Psychiatry & the psychedelic drugs. Past, present & future

scientific article published on 25 December 2017

Psychiatry's next top model: cause for a re-think on drug models of psychosis and other psychiatric disorders

scientific article published on 19 June 2013

Psychopharmacological characterisation of the successive negative contrast effect in rats

scientific article published on 21 March 2015

Psychopharmacological imaging

scientific article published on 01 January 1995

Psychotropic drugs, cardiac arrhythmia, and sudden death

scientific article

Putting the 'A' in atypical: does α2-adrenoceptor antagonism account for the therapeutic advantage of new antipsychotics? ⬇️

scientific article published on 01 January 1994

Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression

scientific article published in January 2017

Quantification of in vivo binding of [3H]RX 821002 in rat brain: evaluation as a radioligand for central alpha 2-adrenoceptors.

scientific article published in November 1992

Question-based Drug Development for psilocybin - Authors' reply

scientific article

RO 15-4513 and its interaction with ethanol

scientific article

RO 15-4513 does not protect rats against the lethal effects of ethanol ⬇️

scientific article published on June 22, 1988

Radiative efficiencies for fluorinated esters: indirect global warming potentials of hydrofluoroethers

article

Radioligands for PET studies of central benzodiazepine receptors and PK (peripheral benzodiazepine) binding sites--current status

scientific article

Randomised controlled study of sleep after nefazodone or paroxetine treatment in out-patients with depression

scientific article published in June 2002

Ranking the harm of non-medically used prescription opioids in the UK.

scientific article published on 14 September 2015

Rapid induction of lorazepam dependence and reversal with flumazenil

scientific article published on 01 January 1988

Rapid tryptophan depletion following cognitive behavioural therapy for panic disorder

scientific article published on 13 October 2009

Rationale for, barriers to, and appropriate medication for the long-term treatment of depression

scientific article published on January 2010

Redistribution of slow wave activity of sleep during pharmacological treatment of depression with paroxetine but not with nefazodone.

scientific article published on 22 June 2009

Reduced heart rate variability in remitted bipolar disorder and recurrent depression

scientific article

Reduced thalamic grey matter volume in opioid dependence is influenced by degree of alcohol use: a voxel-based morphometry study

scientific article

Regional GABA concentration and [3H]-diazepam binding in rat brain following repeated electroconvulsive shock ⬇️

scientific article published on 01 January 1983

Regional neurotransmitter responses after acute and chronic electroconvulsive shock

scientific article published on 01 January 1990

Relationship between imidazoline(2) sites and monoamine oxidase

scientific article published in December 2003

Relationship of neurotransmitters to the symptoms of major depressive disorder.

scientific article

Repeated administration of subconvulsant doses of GABA antagonist drugs

Repeated administration of subconvulsant doses of GABA antagonist drugs

scientific article published on 01 January 1982

Repeated electroconvulsive shock does not change [3H]-paroxetine binding to the 5-HT uptake site in rat cortical membranes

scientific article

Repeated electroconvulsive shock does not increase the susceptibility of rats to a cage convulsant (Isopropylbicyclophosphate)

scientific article published on 01 October 1980

Repeated electroconvulsive shock increases the number of [3H]desipramine binding sites in rat cerebral cortex

scientific article

Repeated electroconvulsive shock normalizes blood glucose levels in genetically obese mice (C57BL/6J ob/ob) but not in genetically diabetic mice (C57BL/KsJ db/db)

scientific article published on 01 May 1988

Reply to OCD letter

scientific article published in May 2008

Resolution of sleepiness and fatigue in major depressive disorder: A comparison of bupropion and the selective serotonin reuptake inhibitors

scientific article

Resting state synchrony in anxiety-related circuits of abstinent alcohol-dependent patients

scientific article published in November 2013

Restrictions on drugs with medical value: Moving beyond stalemate

scientific article published on 02 October 2018

Reviews : Antisense oligonucleotides in psychopharmacology and behaviour: promises and pitfalls ⬇️

scientific article published on January 1, 1997

Rob Kerwin--an appreciation

scientific article published in May 2007

Role of GABA in anxiety and depression

scientific article

Role of GABA in memory and anxiety

scientific article published on January 1996

Saccadic eye movement parameters in normal subjects ⬇️

scientific article published on 01 January 1993

Science and non-science in UK drug policy

scientific article published in July 2010

Scopolamine: useful medicine or dangerous drug?

scientific article

Searching for perfect sleep: the continuing evolution of GABAA receptor modulators as hypnotics

scientific article

Seizures in a night club

scientific article published in The Lancet

Selective D3 receptor antagonism modulates neural response during negative emotional processing in substance dependence

Selective changes in the in vivo effects of benzodiazepine receptor ligands after chemical kindling with FG 7142

scientific article published on 01 January 1987

Selective delta-opioid receptor ligands: potential PET ligands based on naltrindole.

scientific article published in April 2001

Selective effect of lithium on cognitive performance in man.

scientific article published on January 1987

Serotonin 5-HT1A receptor binding in people with panic disorder: positron emission tomography study

scientific article

Serotonin and brain function: a tale of two receptors

scientific article published on August 2017

Serotonin and panic

scientific article published in June 1998

Serotonin and sensitivity to trauma-related exposure in selective serotonin reuptake inhibitors-recovered posttraumatic stress disorder

scientific article

Serotonin release measured in the human brain: a PET study with [11C]CIMBI-36 and d-amphetamine challenge

scientific article published on 12 November 2019

Serotonin transporter promoter region polymorphisms do not influence treatment response to escitalopram in patients with major depression

scientific article published on 9 March 2009

Sertraline, a selective serotonin reuptake inhibitor modulates extracellular noradrenaline in the rat frontal cortex

scientific article published in January 1998

Seven genomic subtypes of chronic fatigue syndrome/myalgic encephalomyelitis: a detailed analysis of gene networks and clinical phenotypes.

scientific article published on 5 December 2007

Severity of depression and response to antidepressants: GENPOD randomised controlled trial

scientific article published on 22 December 2011

Should the supply of cannabis be legalised now?

scientific article published on 03 July 2019

Significant decreases in frontal and temporal [11C]-raclopride binding after THC challenge

scientific article published on 6 May 2010

Significant reductions in human visual gamma frequency by the gaba reuptake inhibitor tiagabine revealed by robust peak frequency estimation.

scientific article

Single chemical entity legal highs: assessing the risk for long term harm.

scientific article published on December 2012

Sleep Disorders

article

Sleep and daytime sleepiness the next day following single night-time dose of fluvoxamine, dothiepin and placebo in normal volunteers

scientific article published in January 2000

Sleep and its disorders in translational medicine

scientific article published on 13 April 2011

Sleep changes during long-term treatment of depression with fluvoxamine--a home-based study

scientific article published in May 2000

Sleep disorders as core symptoms of depression

scientific article

Smaller fleas ad infinitum: pharmacological subtypes of anxiety?: The Psychopharmacology of Panic Disorder. November 2nd 1990--Royal Society, London

scientific article published on 01 January 1991

So near yet so far: why won't the UK prescribe medical cannabis?

scientific article published on 21 September 2020

Social phobia: illness or illusion?

scientific article published on 01 April 2001

Spectral signatures of serotonergic psychedelics and glutamatergic dissociatives

scientific article published on 24 June 2019

Stimulants: use and abuse in the treatment of attention deficit hyperactivity disorder

scientific article

Strain differences in response to a benzodiazepine receptor inverse agonist (FG 7142) in mice

scientific article published on 01 January 1988

Strain differences in sensitivity to the hypothermic effects of benzodiazepine receptor ligands in mice

scientific article published on January 1, 1992

Stratified medicine for mental disorders

scientific article published on 04 October 2013

Stratified medicine in psychiatry: a worrying example or new opportunity in the treatment of anxiety?

scientific article published on 20 April 2012

Striatal dopamine D₂/D₃ receptor binding in pathological gambling is correlated with mood-related impulsivity

scientific article

Structural and functional brain changes in posttraumatic stress disorder.

scientific article

Studies of alpha-2-adrenoceptor function in abstinent alcoholics

scientific article published in January 1989

Studies on [3H]diazepam and [3H]ethyl-beta-carboline carboxylate binding to rat brain in vivo. I. Regional variations in displacement

scientific article published on December 1983

Studies on [3H]diazepam and [3H]ethyl-beta-carboline carboxylate binding to rat brain in vivo. II. Effects of electroconvulsive shock

scientific article published on December 1983

Studies on the post-ictal rise in seizure threshold ⬇️

scientific article published on May 8, 1981

Substance P antagonists: novel agents in the treatment of depression

scientific article

Substitution therapy for alcoholism: time for a reappraisal?

scientific article published on 8 July 2011

Successful treatment of night terrors and somnambulism with paroxetine

scientific article published in April 1994

Synthesis of 2,3,5,6-tetrahydro-3H-imidazo[2,1-b] [1,3,5]benzotriazepines and their oxidative ring contraction into 1-(4,5-dihydro-1H-imidazol-2-yl)-1H-benzimidazoles

scientific article

THuNDRous news for human dopamine researchers: A selective dopamine D1 receptor antagonist will soon be available for clinical research

scientific article published on 24 October 2018

TNF alpha mimics the endocrine but not the thermoregulatory responses of bacterial lipopolysaccharide (LPS): correlation with FOS-expression in the brain

scientific article published in March 1996

Tapering of SSRI treatment to mitigate withdrawal symptoms

That warm fuzzy feeling: brain serotonergic neurons and the regulation of emotion

scientific article published on 12 December 2008

The 5-HT3 antagonist ondansetron reduces gastrointestinal side effects induced by a specific serotonin re-uptake inhibitor in man

article

The Australian drug harms ranking study

scientific article published on 13 May 2019

The Current Status of Psychedelics in Psychiatry

scientific article published on 29 July 2020

The Effects of Acutely Administered 3,4-Methylenedioxymethamphetamine on Spontaneous Brain Function in Healthy Volunteers Measured with Arterial Spin Labeling and Blood Oxygen Level-Dependent Resting State Functional Connectivity

scientific article

The Effects of Electroconvulsive Therapy on Plasma Insulin and Glucose in Depression ⬇️

scientific article published on 01 July 1992

The Hamilton Depression Scale--accelerator or break on antidepressant drug discovery?

scientific article published in February 2014

The ICCAM platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part B: fMRI description

scientific article published on 04 October 2016

The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description

scientific article

The Standard Joint Unit

scientific article published on 16 May 2017

The administration of psilocybin to healthy, hallucinogen-experienced volunteers in a mock-functional magnetic resonance imaging environment: a preliminary investigation of tolerability

scientific article published on 15 April 2010

The anxiogenic action of benzodiazepine antagonists

scientific article published in October 1982

The approach to new anxiolytics

scientific article published on April 1993

The benzodiazepine antagonist, Ro 15-1788 does not decrease ethanol withdrawal convulsions in rats

scientific article published on 01 January 1985

The brain GABA-benzodiazepine receptor alpha-5 subtype in autism spectrum disorder: a pilot [(11)C]Ro15-4513 positron emission tomography study

scientific article published on 21 April 2012

The cardiovascular and subjective effects of thyrotropin releasing hormone (TRH) and a stable analogue, dimethyl proline-TRH, in healthy volunteers.

scientific article

The clinical use of buprenorphine in opiate addiction: evidence and practice.

scientific article published in October 2004

The criteria of Cloninger et al. and von Knorring et al. for subgrouping alcoholics: a comparison in a clinical population ⬇️

scientific article published on December 1, 1991

The development and validation of a human screening model of tobacco abstinence

scientific article published on 06 November 2019

The dopamine theory of addiction: 40 years of highs and lows

scientific article

The effect of 1-(4,5-dihydro-1H-imidazol-2-yl) isoquinoline on monoamine release and turnover in the rat frontal cortex

scientific article

The effect of 6-week treatment with escitalopram on CCK-4 challenge: a placebo-controlled study in CCK-4-sensitive healthy volunteers

scientific article published on 29 August 2012

The effect of a clinically effective and non-effective dose of lorazepam on 7.5% CO₂-induced anxiety

scientific article published on 2 October 2012

The effect of acute and chronic electroconvulsive shock on [3H]phorbol-dibutyrate binding to rat brain membranes

scientific article published on 01 November 1988

The effect of acutely administered MDMA on subjective and BOLD-fMRI responses to favourite and worst autobiographical memories

scientific article

The effect of clonidine on plasma MHPG: evidence against tonic alpha 2-adrenoceptor control of noradrenergic function

scientific article published on 01 January 1986

The effect of diazepam on indices of 5-HT function in man.

scientific article published in May 1986

The effect of intravenous flumazenil on interictal electroencephalographic epileptic activity: results of a placebo-controlled study

scientific article published on April 1991

The effect of lithium on 5-HT-mediated neuroendocrine responses and platelet 5-HT receptors

scientific article published in January 1986

The effect of nicotine on striatal dopamine release in man: A [11C]raclopride PET study

scientific article

The effect of repeated electroconvulsive shock on the function of THIP, a GABA agonist ⬇️

scientific article published on October 1, 1984

The effect of the imidazodiazepine Ro 15-4513 on the anticonvulsant effects of diazepam, sodium pentobarbital and ethanol

scientific article published in June 1987

The effects and after effects of the α2-adrenoceptor antagonist idazoxan on mood, memory and attention in normal volunteers ⬇️

scientific article published on January 1, 1992

The effects of 7.5% carbon dioxide inhalation on task performance in healthy volunteers

scientific article published on 2 September 2011

The effects of drugs acting at the GABAA-receptor/ionophore after chemical kindling with the benzodiazepine receptor ligand FG 7142.

scientific article published on July 1986

The effects of elevated endogenous GABA levels on movement-related network oscillations

scientific article published on 27 October 2012

The effects of flumazenil in neuropsychiatric disorders.

scientific article published on June 1995

The effects of idazoxan and other alpha 2-adrenoceptor antagonists on urine output in the rat.

scientific article published on June 1992

The effects of idazoxan and other α2-adrenoceptor antagonists on food and water intake in the rat ⬇️

scientific article published on September 1, 1991

The effects of idazoxan on reaction times, eye movements and the mood of healthy volunteers and patients with upper respiratory tract illnesses

scientific article published in January 1999

The effects of levetiracetam on objective and subjective sleep parameters in healthy volunteers and patients with partial epilepsy

scientific article published in September 2002

The effects of psilocybin and MDMA on between-network resting state functional connectivity in healthy volunteers

scientific article

The effects of single dose anxiolytic medication on the CO2 models of anxiety: differentiation of subjective and objective measures.

scientific article published on 2 October 2008

The effects of the α2-adrenoceptor antagonist idazoxan on sleep in normal volunteers ⬇️

scientific article published on January 1, 1991

The entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs

scientific article published in 2014

The entropic tongue: Disorganization of natural language under LSD

scientific article published on 08 December 2020

The extinction of drugs for clinical research: Can the ECNP medicines chest save them?

scientific article published on 23 January 2014

The feasibility of abrupt methadone-buprenorphine transfer in British opiate addicts in an outpatient setting

scientific article published on 01 April 1997

The full cost and burden of disorders of the brain in Europe exposed for the first time

scientific article published in October 2011

The hidden therapist: evidence for a central role of music in psychedelic therapy

scientific article published on 2 February 2018

The hidden third: improving outcome in treatment-resistant depression

scientific article published on 11 January 2012

The hypothermic response to clonidine is absent in alcohol withdrawal but returns in abstinence

scientific article published on 1 May 1988

The influence of different cellular environments on PET radioligand binding: an application to D2/3-dopamine receptor imaging

scientific article

The modulatory action of harmane on serotonergic neurotransmission in rat brain

scientific article

The neurobiology of social phobia

scientific article

The neurochemistry of anxiety: an update

scientific article published on January 1990

The neuropharmacology of serotonin and noradrenaline in depression.

scientific article

The other face of depression, reduced positive affect: the role of catecholamines in causation and cure

scientific article

The paradoxical psychological effects of lysergic acid diethylamide (LSD).

scientific article published on 5 February 2016

The pharmacology of human anxiety

scientific article published on January 1990

The physical health challenges in patients with severe mental illness: cardiovascular and metabolic risks

article

The processing of automatic thoughts of drug use and craving in opiate-dependent individuals

scientific article published in November 2000

The psychobiology of anxiolytic drug. Part 2: Pharmacological treatments of anxiety

scientific article

The psychobiology of anxiolytic drugs. Part 1: Basic neurobiology

scientific article

The psychobiology of posttraumatic stress disorder

scientific article

The psychopharmacology of anxiety.

scientific article published on February 1996

The psychopharmacology of social communication and its disorders: November 1992, London

scientific article published on 01 January 1993

The role of central noradrenergic dysregulation in anxiety disorders: evidence from clinical studies

scientific article published on 08 June 2010

The role of dopamine and norepinephrine in depression and antidepressant treatment.

scientific article published on January 2006

The role of serotonin in panic: evidence from tryptophan depletion studies

scientific article published on April 2004

The role of the opioid system in alcohol dependence

scientific article

The size, burden and cost of disorders of the brain in the UK.

scientific article published on 24 July 2013

The tangible common denominator of substance use disorders: a reply to commentaries to Rehm et al. (2013a).

scientific article published on 12 November 2013

The unhappy saga of 'happy pills'

scientific article published on 01 September 2003

The uptake of a fluorescently labelled antisense oligonucleotide in vitro and in vivo

scientific article published on 15 April 2005

The use of benzodiazepines in anxiety and other disorders

scientific article

The use of sleep measures to compare a new 5HT1A agonist with buspirone in humans

scientific article

Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern-era clinical studies

scientific article published on 30 October 2020

Therapeutic mechanisms of psilocybin: Changes in amygdala and prefrontal functional connectivity during emotional processing after psilocybin for treatment-resistant depression

scientific article published on 16 January 2020

Thirty years of Journal of Psychopharmacology

scientific article

Through a glass darkly: can we improve clarity about mechanism and aims of medications in drug and alcohol treatments?

Thyroid hormones do not alter rat brain benzodiazepine receptor function in-vivo ⬇️

scientific article published on November 1, 1983

Thyrotropin-releasing hormone selectively reverses lorazepam-induced sedation but not slowing of saccadic eye movements

scientific article published on January 1, 1992

Tolerability and safety aspects of mirtazapine

scientific article

Towards earlier diagnosis and treatment of disorders of the brain.

scientific article published in May 2018

Toxicological evaluation of 5-methoxy-2-aminoindane (MEAI): Binge mitigating agent in development

scientific article

Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

scientific article

Treatment of anxiety and depressive disorders in patients with cardiovascular disease

scientific article published on April 2004

Tripping up addiction: the use of psychedelic drugs in the treatment of problematic drug and alcohol use

article published in 2017

Tryptophan depletion does not modify response to CCK-4 challenge in patients with panic disorder after treatment with citalopram

scientific article published on 16 March 2006

Tryptophan depletion reverses the therapeutic effect of selective serotonin reuptake inhibitors in social anxiety disorder

scientific article published in October 2004

Tryptophan metabolism in the central nervous system: medical implications

scientific article

Tryptophan research in panic disorder

scientific article

Uncritical positive regard? Issues in the efficacy and safety of psychotherapy

scientific article published on 01 January 2008

Understanding the neurobiology of comorbidity in anxiety disorders.

scientific article published on October 2006

Unusual interactions of benzodiazepine receptor antagonists.

scientific article

Use of selective serotonin reuptake inhibitors and other serotonergic drugs in the biological dissection of affective disorders.

scientific article published on January 1995

User perceptions of the benefits and harms of hallucinogenic drug use: A web-based questionnaire study

Using Baclofen to Explore GABA-B Receptor Function in Alcohol Dependence: Insights From Pharmacokinetic and Pharmacodynamic Measures

Using Ro 15-1788 to investigate the benzodiazepine receptor in vivo: studies on the anticonvulsant and sedative effect of melatonin and the convulsant effect of the benzodiazepine Ro 05-3663.

scientific article

Using [(11)C]Ro15 4513 PET to characterise GABA-benzodiazepine receptors in opiate addiction: Similarities and differences with alcoholism

scientific article

Using [11C]diprenorphine to image opioid receptor occupancy by methadone in opioid addiction: clinical and preclinical studies

scientific article published on 3 September 2004

Using saccadic eye movements as objective measures of tolerance in methadone dependent individuals during the hydromorphone challenge test ⬇️

scientific article published on March 1, 2003

Using sleep to evaluate comparative serotonergic effects of paroxetine and citalopram

scientific article published in October 2004

Validated Method for the Quantification of Baclofen in Human Plasma Using Solid-Phase Extraction and Liquid Chromatography-Tandem Mass Spectrometry

scientific article published on 4 November 2015

Validating the inhalation of 7.5% CO(2) in healthy volunteers as a human experimental medicine: a model of generalized anxiety disorder (GAD).

scientific article published on September 2011

Variation in binding affinity of the novel anxiolytic XBD173 for the 18 kDa translocator protein in human brain

scientific article published on 01 March 2011

Venlafaxine occupation at the noradrenaline reuptake site: in-vivo determination in healthy volunteers

scientific article

Venlafaxine: a new class of antidepressant

scientific article

Venlafaxine: the yin and yang of antidepressants? ⬇️

scientific article published on 01 January 1995

Vienna Declaration: a call for evidence-based drug policies

scientific article published in The Lancet

Vitamin C, Mood and Cognitive Functioning in the Elderly

scientific article published in January 1999

Voluntary exercise alters GABA(A) receptor subunit and glutamic acid decarboxylase-67 gene expression in the rat forebrain

scientific article published on 18 September 2008

WCA Recommendations for the Long-Term Treatment of Generalized Anxiety Disorder

WCA Recommendations for the long-term treatment of posttraumatic stress disorder.

scientific article published on August 2003

WCA recommendations for the long-term treatment of generalized anxiety disorder

scientific article (publication date: August 2003)

WCA recommendations for the long-term treatment of obsessive-compulsive disorder in adults.

scientific article published on August 2003

WCA recommendations for the long-term treatment of panic disorder.

scientific article published on August 2003

WCA recommendations for the long-term treatment of social phobia.

scientific article published on August 2003

Was it a vision or a waking dream?

scientific article

What one hand giveth the other taketh away: some unpredicted effects of enantiomers in psychopharmacology

scientific article published on August 2010

Where now for schizophrenia research?

scientific article

Which antidepressants have demonstrated superior efficacy? A review of the evidence

scientific article

Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression.

scientific article published on 7 August 2013

Whole-genome expression analysis reveals genes associated with treatment response to escitalopram in major depression

scientific article published on 22 July 2016

Why Less Is Always More in the Treatment of Alcohol Use Disorders

scientific article published on 01 April 2019

Why does the world have such a 'down' on antidepressants?

scientific article

Why medical cannabis is still out of patients' reach-an essay by David Nutt

scientific article published on 01 May 2019

Women with diarrhoea-predominant irritable bowel syndrome show an increased pressure response to 35% carbon dioxide stress challenge

scientific article published in January 2009

[3H]2-(2-benzofuranyl)-2-imidazoline: a new selective high affinity radioligand for the study of rabbit brain imidazoline I2 receptors

scientific article published on 01 May 1996

beta-carboline binding to imidazoline receptors

scientific article

γ-aminobutyric acid as a metabolite: Interpreting magnetic resonance spectroscopy experiments

scientific article published on 22 March 2016

Paulina is supported by:

About Paulina

Help