List of works - Leonardo Bottolo

A Bayesian Approach for Analysis of Whole-Genome Bisulfite Sequencing Data Identifies Disease-Associated Changes in DNA Methylation

scientific article

A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels

scientific article (publication date: 2012)

A second generation human haplotype map of over 3.1 million SNPs

scientific article

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

scientific article published on 8 September 2010

Author Correction: WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling

scientific article published on 09 September 2019

Bayesian Hierarchical Mixture Models

Bayesian Models for Sparse Regression Analysis of High Dimensional Data*

Bayesian detection of expression quantitative trait loci hot spots

scientific article published on 16 September 2011

Deciphering the complex: methodological overview of statistical models to derive OMICS-based biomarkers

scientific article published on 05 August 2013

Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue.

scientific article

ESS++: a C++ objected-oriented algorithm for Bayesian stochastic search model exploration

scientific article published on 13 January 2011

Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function

scientific article

Expression QTLs Mapping and Analysis: A Bayesian Perspective

scientific article published on January 2017

Functionally Conserved Noncoding Regulators of Cardiomyocyte Proliferation and Regeneration in Mouse and Human

scientific article published on 01 February 2018

GUESS-ing polygenic associations with multiple phenotypes using a GPU-based evolutionary stochastic search algorithm

scientific article

Genome-wide detection and characterization of positive selection in human populations

scientific article

Low copy number of the salivary amylase gene predisposes to obesity.

scientific article published on 30 March 2014

MT-HESS: an efficient Bayesian approach for simultaneous association detection in OMICS datasets, with application to eQTL mapping in multiple tissues

scientific article

Metabolic effects of bezafibrate in mitochondrial disease

scientific article published on 28 February 2020

MethylCal: Bayesian calibration of methylation levels

scientific article published on 01 August 2019

Misspecification and Domain Issues in Fitting Garch(1, 1) Models: A Monte Carlo Investigation

Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules

scientific article published on 2 January 2014

New insights into the genetic control of gene expression using a Bayesian multi-tissue approach

scientific article

Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity

scientific article

Particle MCMC algorithms and architectures for accelerating inference in state-space models

scientific article

R2GUESS: A Graphics Processing Unit-Based R Package for Bayesian Variable Selection Regression of Multivariate Responses.

scientific article published in January 2016

Stationarity domains for -power Garch process with heavy tails

Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

scientific article

Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease

scientific article published on 21 December 2015

Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans

scientific article published on 31 October 2012

The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age.

scientific article

The distribution and causes of meiotic recombination in the human genome

scientific article

WGBSSuite: simulating whole-genome bisulphite sequencing data and benchmarking differential DNA methylation analysis tools

scientific article

WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling

scientific article published on 09 August 2019

Wars2 is a determinant of angiogenesis.

scientific article

List of works by Leonardo Bottolo

A Bayesian Approach for Analysis of Whole-Genome Bisulfite Sequencing Data Identifies Disease-Associated Changes in DNA Methylation

A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels

A second generation human haplotype map of over 3.1 million SNPs

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk

Author Correction: WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling

Bayesian Hierarchical Mixture Models

Bayesian Models for Sparse Regression Analysis of High Dimensional Data*

Bayesian detection of expression quantitative trait loci hot spots

Deciphering the complex: methodological overview of statistical models to derive OMICS-based biomarkers

Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue.

ESS++: a C++ objected-oriented algorithm for Bayesian stochastic search model exploration

Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function

Expression QTLs Mapping and Analysis: A Bayesian Perspective

Functionally Conserved Noncoding Regulators of Cardiomyocyte Proliferation and Regeneration in Mouse and Human

GUESS-ing polygenic associations with multiple phenotypes using a GPU-based evolutionary stochastic search algorithm

Genome-wide detection and characterization of positive selection in human populations

Low copy number of the salivary amylase gene predisposes to obesity.

MT-HESS: an efficient Bayesian approach for simultaneous association detection in OMICS datasets, with application to eQTL mapping in multiple tissues

Metabolic effects of bezafibrate in mitochondrial disease

MethylCal: Bayesian calibration of methylation levels

Misspecification and Domain Issues in Fitting Garch(1, 1) Models: A Monte Carlo Investigation

Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules

New insights into the genetic control of gene expression using a Bayesian multi-tissue approach

Novel association approach for variable number tandem repeats (VNTRs) identifies DOCK5 as a susceptibility gene for severe obesity

Particle MCMC algorithms and architectures for accelerating inference in state-space models

R2GUESS: A Graphics Processing Unit-Based R Package for Bayesian Variable Selection Regression of Multivariate Responses.

Stationarity domains for -power Garch process with heavy tails

Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease

Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans

The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age.

The distribution and causes of meiotic recombination in the human genome

WGBSSuite: simulating whole-genome bisulphite sequencing data and benchmarking differential DNA methylation analysis tools

WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling

Wars2 is a determinant of angiogenesis.