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List of works by Jennifer Wargo

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

851 resected cystic tumors of the pancreas: A 33-year experience at the Massachusetts General Hospital ⬇️

scientific article published on 06 July 2012

9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapy

scientific article published on 23 September 2021

A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

scientific article published in November 2017

A PAX3/BRN2 rheostat controls the dynamics of BRAF mediated MITF regulation in MITF /AXL melanoma

scientific article published on 19 October 2018

A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling.

scientific article published in March 2018

A TCR targeting the HLA-A*0201-restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer.

scientific article published on 13 December 2010

A landscape of driver mutations in melanoma

scientific article

A melanocyte lineage program confers resistance to MAP kinase pathway inhibition

scientific article published on 3 November 2013

A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors

scientific article

A phase II study of combined therapy with a BRAF inhibitor (vemurafenib) and interleukin-2 (aldesleukin) in patients with metastatic melanoma

scientific article published in February 2018

A potential role for immunotherapy in thyroid cancer by enhancing NY-ESO-1 cancer antigen expression

scientific article

A prospective study of the adaptive changes in the gut microbiome during standard-of-care chemoradiotherapy for gynecologic cancers

scientific article published on 04 March 2021

AI finds microbial signatures in tumours and blood across cancer types

scientific article published on 01 March 2020

Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells

scientific article published on 01 August 2020

An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition

scientific article

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background

scientific article

Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade

scientific article published on 14 June 2016

Analysis of the immune infiltrate in undifferentiated pleomorphic sarcoma of the extremity and trunk in response to radiotherapy: Rationale for combination neoadjuvant immune checkpoint inhibition and radiotherapy

scientific article published on 31 October 2017

Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy

scientific article published on 15 June 2022

Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3+ Regulatory T Cells (Tregs) in Human Cancers-Response

scientific article published on 01 June 2019

Anti-CTLA-4 immunotherapy does not deplete FOXP3+ regulatory T cells (Tregs) in human cancers

scientific article published on 27 July 2018

Assessment of pancreatic tumor resectability with multidetector computed tomography: semiautomated console-generated images versus dedicated workstation-generated images

scientific article published on August 2008

Association between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes

scientific article published on 22 April 2017

Association of Vitamin D Levels With Outcome in Patients With Melanoma After Adjustment For C-Reactive Protein

scientific article published on 21 March 2016

Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis.

scientific article published on 12 February 2018

Author Correction: Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

scientific article published on 01 January 2019

Author Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

scientific article published on 01 December 2018

Author Correction: PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance

scientific article published on 01 November 2019

Author Correction: Tertiary lymphoid structures improve immunotherapy and survival in melanoma

scientific article published on 01 April 2020

Autoimmune antibodies correlate with immune checkpoint therapy-induced toxicities

scientific article published on 14 October 2019

B cells and tertiary lymphoid structures promote immunotherapy response

scientific article published on 15 January 2020

B cells are associated with survival and immunotherapy response in sarcoma

scientific article published on 15 January 2020

B7-H3 Expression in Merkel Cell Carcinoma-Associated Endothelial Cells Correlates with Locally Aggressive Primary Tumor Features and Increased Vascular Density

scientific article published on 26 February 2019

BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition.

scientific article published on 27 February 2013

BRAF Inhibition Generates a Host-Tumor Niche that Mediates Therapeutic Escape

scientific article

BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice ⬇️

scientific article published on November 30, 2012

BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma.

scientific article published on 10 January 2013

BRAF inhibition is associated with increased clonality in tumor-infiltrating lymphocytes

scientific article published on 15 October 2013

Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma

scientific article published on 28 April 2017

Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase.

scientific article published on 28 April 2010

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

scientific article (publication date: 16 December 2010)

Can we harness the microbiota to enhance the efficacy of cancer immunotherapy?

scientific article published on 13 July 2020

Cancer Genomics in Clinical Context

scientific article

Cancer immunotherapy highlights from the 2014 ASCO Meeting

Case records of the Massachusetts General Hospital. Case 21-2013. A 68-year-old man with metastatic melanoma

scientific article published in July 2013

Circulating Tumor Cells and Early Relapse in Node-positive Melanoma

scientific article published on 03 February 2020

Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics

scientific article

Clinical utility of a blood-based BRAF(V600E) mutation assay in melanoma

scientific article

Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial

scientific article published on 28 April 2016

Clinicopathological features and clinical outcomes associated with TP53 and BRAFNon-V600 mutations in cutaneous melanoma patients

scientific article published on 2 December 2016

Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma

scientific article

Combination BRAF-Directed Therapy and Immunotherapy

Combination Immunotherapy Development in Melanoma

article

Combination anti-CTLA-4 plus anti-PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies

scientific article published on 21 October 2019

Combined Analysis of Antigen Presentation and T-cell Recognition Reveals Restricted Immune Responses in Melanoma

article

Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma

scientific article published in 2022

Combining checkpoint inhibitors and BRAF-targeted agents against metastatic melanoma.

scientific article published on May 2013

Combining targeted therapy and immune checkpoint inhibitors in the treatment of metastatic melanoma

scientific article

Comparative immunologic characterization of autoimmune giant cell myocarditis with ipilimumab

scientific article published on 8 August 2017

Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer

scientific article published on 11 January 2019

Comprehensive T cell repertoire characterization of non-small cell lung cancer

scientific article published on 30 January 2020

Concepts Collide: Genomic, Immune, and Microbial Influences on the Tumor Microenvironment and Response to Cancer Therapy.

scientific article published on 4 May 2018

Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab

scientific article published on 03 January 2020

Corrigendum: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance

scientific article

Cumulative Incidence and Predictors of CNS Metastasis for Patients With American Joint Committee on Cancer 8th Edition Stage III Melanoma

scientific article published on 28 January 2020

Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma

scientific article published on 01 November 2018

Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma

scientific article published on 01 January 2019

Density, Distribution, and Composition of Immune Infiltrates Correlate with Survival in Merkel Cell Carcinoma

scientific article published on 10 May 2016

Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade

scientific article published on 9 August 2017

Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma

scientific article published on 2 February 2016

Diverse types of dermatologic toxicities from immune checkpoint blockade therapy

scientific article published on 10 November 2016

Does It MEK a Difference? Understanding Immune Effects of Targeted Therapy

scientific article published on 29 May 2015

Does the mechanism of lymph node invasion affect survival in patients with pancreatic ductal adenocarcinoma?

scientific article

Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.

scientific article

EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of BRAF-Mutant Colorectal Cancers to RAF Inhibition with Vemurafenib ⬇️

scientific article published on January 16, 2012

EPHA2 is a mediator of vemurafenib resistance and a novel therapeutic target in melanoma

scientific article

Effective innate and adaptive antimelanoma immunity through localized TLR7/8 activation

scientific article

Elucidating distinct roles for NF1 in melanomagenesis

scientific article

Enhanced tumor responses to dendritic cells in the absence of CD8-positive cells

scientific article published on April 2004

Evidence of synergy with combined BRAF-targeted therapy and immune checkpoint blockade for metastatic melanoma

scientific article published on October 2014

Evolution of the Whipple procedure at the Massachusetts General Hospital ⬇️

scientific article published on July 6, 2012

Expression of PD-1 and PD-L1 in Extramammary Paget Disease: Implications for Immune-Targeted Therapy

scientific article published on 29 May 2019

FOLFIRINOX in Locally Advanced Pancreatic Cancer: The Massachusetts General Hospital Cancer Center Experience ⬇️

scientific article published on May 8, 2013

Feasibility of Ultra-High-Throughput Functional Screening of Melanoma Biopsies for Discovery of Novel Cancer Drug Combinations

scientific article published on 26 April 2017

Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients

scientific article published on 10 December 2020

Fecal microbiota transplantation as a mean of overcoming immunotherapy-resistant cancers – hype or hope?

scientific article published on 28 September 2021

Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis

scientific article published on 12 November 2018

Functional annotation of melanoma risk loci identifies novel susceptibility genes

scientific article published on 21 October 2019

Future perspectives in melanoma research "Melanoma Bridge", Napoli, November 30th-3rd December 2016. ⬇️

scientific article published on 16 November 2017

Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015.

scientific article

Gene Targeting Meets Cell-Based Therapy: Raising the Tail, or Merely a Whimper?

scientific article published on 11 November 2016

Gene expression profiling of lichenoid dermatitis immune-related adverse event from immune checkpoint inhibitors reveals increased CD14+ and CD16+ monocytes driving an innate immune response

scientific article published on 11 April 2019

Genetic and Genomic Characterization of 462 Melanoma Patient-Derived Xenografts, Tumor Biopsies, and Cell Lines

scientific article published in November 2017

Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma.

scientific article

Granulomatous/sarcoid-like lesions associated with checkpoint inhibitors: a marker of therapy response in a subset of melanoma patients

scientific article published on 12 February 2018

Gut Microbiome Modulates Response to Cancer Immunotherapy

scientific article published on 01 March 2020

Gut Microbiome Modulation Via Fecal Microbiota Transplant to Augment Immunotherapy in Patients with Melanoma or Other Cancers

scientific article published on 24 June 2020

Gut Microbiome Signatures are Predictive of Infectious Risk Following Induction Therapy for Acute Myeloid Leukemia

scientific article published on 22 August 2019

Gut microbes as biomarkers of ICI response — sharpening the focus

scientific article published on 21 April 2022

Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation

scientific article published on 22 February 2021

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.

scientific article published on 2 November 2017

Hallmarks of response to immune checkpoint blockade

scientific article

High expression of PD-1 and PD-L1 in ocular adnexal sebaceous carcinoma

scientific article published on 26 July 2018

Histopathological features of complete pathological response predict recurrence-free survival following neoadjuvant targeted therapy for metastatic melanoma

scientific article published on 30 July 2020

Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.

scientific article published on 08 October 2013

Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma

scientific article published on 25 July 2016

Immune Checkpoint Blockade across the Cancer Care Continuum

scientific article published on 01 June 2018

Immune Effects of Chemotherapy, Radiation, and Targeted Therapy and Opportunities for Combination With Immunotherapy

scientific article

Immune and Circulating Tumor DNA Profiling After Radiation Treatment for Oligometastatic Non-Small Cell Lung Cancer: Translational Correlatives from a Mature Randomized Phase II Trial

scientific article published on 31 October 2019

Immunotherapy resistance: the answers lie ahead - not in front - of us.

scientific article published on 21 February 2017

Implementation of a Pan-Genomic Approach to Investigate Holobiont-Infecting Microbe Interaction: A Case Report of a Leukemic Patient with Invasive Mucormycosis

scientific article published on 10 November 2015

Implications of incidentally discovered, nonfunctioning pancreatic endocrine tumors: short-term and long-term patient outcomes

scientific article published on May 2011

Incidental pancreatic cysts: do we really know what we are watching?

scientific article published on 17 May 2010

Influences of BRAF Inhibitors on the Immune Microenvironment and the Rationale for Combined Molecular and Immune Targeted Therapy.

scientific article published on July 2016

Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy

scientific article published on March 2016

Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma

scientific article published on 8 October 2014

Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.

scientific article

Interaction of molecular alterations with immune response in melanoma.

scientific article

Intra-patient intra-tumoral immune heterogeneity is evident at progression on targeted therapy and immunotherapy for melanoma

Intraductal papillary mucinous neoplasms: does a family history of pancreatic cancer matter?

scientific article published on 15 June 2012

Landscape of Targeted Anti-Cancer Drug Synergies in Melanoma Identifies a Novel BRAF-VEGFR/PDGFR Combination Treatment

scientific article (publication date: 2015)

Linking Associations of Rare Low-Abundance Species to Their Environments by Association Networks.

scientific article

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

scientific article published on 09 September 2016

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

scientific article published on 8 December 2015

Lymphoepithelial cysts and cystic lymphangiomas: Under-recognized benign cystic lesions of the pancreas

scientific article

MAP kinase pathway alterations in BRAF-mutant melanoma patients with acquired resistance to combined RAF/MEK inhibition

scientific article

MITF Modulates Therapeutic Resistance through EGFR Signaling

scientific article published on 19 March 2015

Melanoma Evolves Complete Immunotherapy Resistance through the Acquisition of a Hypermetabolic Phenotype

scientific article published on 11 September 2020

Melanoma genome sequencing reveals frequent PREX2 mutations

scientific article

Metastatic Tumors in the Pancreas in the Modern Era ⬇️

scientific article published on December 1, 2010

Metastatic melanoma with balloon/histiocytoid cytomorphology after treatment with immunotherapy: A histologic mimic and diagnostic pitfall

scientific article published on 18 May 2018

Modulating the microbiome to improve therapeutic response in cancer

scientific article published on 01 February 2019

Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases

scientific article published on 20 February 2019

Molecular and immune heterogeneity in synchronous melanoma metastases.

scientific article published on 4 November 2015

Monitoring immune responses in the tumor microenvironment

scientific article published on 27 May 2016

N0/N1, PNL, or LNR? The Effect of Lymph Node Number on Accurate Survival Prediction in Pancreatic Ductal Adenocarcinoma ⬇️

scientific article published on December 11, 2012

Natural killer cells play a critical role in the immune response following immunization with melanoma-antigen-engineered dendritic cells

scientific article published in June 2005

Neoadjuvant Therapy for Melanoma: A US Food and Drug Administration - Melanoma Research Alliance Public Workshop

scientific article published on 13 November 2020

Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

scientific article published on 8 October 2018

Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial

scientific article published on 18 February 2021

Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial

scientific article

Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium

scientific article published on 01 July 2019

Neoadjuvant therapy for melanoma: is it ready for prime time?

scientific article published on 03 June 2019

Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer

scientific article published on 19 August 2021

Novel Treatments in Development for Melanoma.

scientific article

Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.

scientific article

Ocular melanoma metastatic to the pancreas after a 28-year disease-free interval

scientific article published on 29 July 2009

Oncogenic BRAF Regulates Oxidative Metabolism via PGC1α and MITF ⬇️

scientific article published on March 7, 2013

Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma

scientific article

Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma

scientific article published on 16 September 2012

PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance

scientific article published on 29 July 2019

PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation

scientific article

Pancreatic ductal adenocarcinoma: Long-term survival does not equal cure ⬇️

scientific article published on July 3, 2012

Pancreatic ductal adenocarcinoma: is there a survival difference for R1 resections versus locally advanced unresectable tumors? What is a "true" R0 resection?

scientific article published on 01 April 2013

Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study.

scientific article

Pathological assessment of resection specimens after neoadjuvant therapy for metastatic melanoma

scientific article published on 01 August 2018

Phase II study of neoadjuvant checkpoint blockade in patients with surgically resectable undifferentiated pleomorphic sarcoma and dedifferentiated liposarcoma

scientific article published on 24 September 2018

Phosphorylated Histone H3 (PHH3) Is a Superior Proliferation Marker for Prognosis of Pancreatic Neuroendocrine Tumors.

scientific article

Pilot study of intratumoral (IT) cryoablation (cryo) in combination with systemic checkpoint blockade in patients with metastatic melanoma (MM).

scientific article published on 4 November 2015

Point of care assessment of melanoma tumor signaling and metastatic burden from μNMR analysis of tumor fine needle aspirates and peripheral blood

scientific article published on 16 December 2016

Poor Response to Neoadjuvant Chemotherapy Correlates with Mast Cell Infiltration in Inflammatory Breast Cancer

scientific article published on 01 May 2019

Potential role of 5-aza-2'-deoxycytidine induced MAGE-A4 expression in immunotherapy for anaplastic thyroid cancer

scientific article published on December 2013

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine

scientific article published on September 2017

Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy

scientific article published on February 2017

Prognostic model for patient survival in primary anorectal mucosal melanoma: stage at presentation determines relevance of histopathologic features

scientific article published on 05 August 2019

Prospective Analysis of Adoptive TIL Therapy in Patients with Metastatic Melanoma: Response, Impact of Anti-CTLA4, and Biomarkers to Predict Clinical Outcome

Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma

scientific article published on 01 December 2018

RAF Inhibitor Therapy Promotes Melanocytic Antigen Expression and Enhanced Anti-Tumor Immunity in Melanoma

RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

scientific article (publication date: 23 November 2011)

Raising the bar: optimizing combinations of targeted therapy and immunotherapy

scientific article published on October 2015

Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression

scientific article published on 02 August 2008

Remodeling of the collagen matrix in aging skin promotes melanoma metastasis and affects immune cell motility

scientific article published on 02 October 2018

Response to BRAF inhibition in melanoma is enhanced when combined with immune checkpoint blockade

scientific article

Role of Immune Response, Inflammation, and Tumor Immune Response-Related Cytokines/Chemokines in Melanoma Progression

scientific article published on 07 June 2019

Role of dendritic cell phenotype, determinant spreading, and negative costimulatory blockade in dendritic cell-based melanoma immunotherapy

scientific article

Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function

scientific article published on 15 June 2010

Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in <i>Braf</i>-mutated melanoma

scientific article published on 06 November 2021

Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions

scientific article published on May 2008

Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma

scientific article published on 15 April 2020

Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma

scientific article published on 12 February 2020

Superior Prognostic Importance of Perineural Invasion vs. Lymph Node Involvement After Curative Resection of Duodenal Adenocarcinoma ⬇️

scientific article published on October 18, 2011

Surgery for small and asymptomatic branch-duct IPMNs

scientific article published on 01 March 2014

Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade

scientific article published on 03 September 2019

Systematic identification of signaling pathways with potential to confer anticancer drug resistance.

scientific article

T CELL REPERTOIRE IN COMBINATION WITH T CELL DENSITY PREDICTS CLINICAL OUTCOMES IN PATIENTS WITH MERKEL CELL CARCINOMA

scientific article published on 15 April 2020

TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: An Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence.

scientific article published on 21 July 2017

TORC1 Suppression Predicts Responsiveness to RAF and MEK Inhibition in BRAF- Mutant Melanoma ⬇️

scientific article published on July 31, 2013

Targeted Therapies Combined With Immune Checkpoint Therapy.

scientific article published on March 2016

Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure

scientific article published on 12 June 2017

Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors

scientific article published on 4 April 2016

Targeting the MAGE A3 antigen in pancreatic cancer ⬇️

scientific article published on July 6, 2012

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

scientific article published on 15 January 2020

Tertiary lymphoid structures with overlapping histopathologic features of cutaneous marginal zone lymphoma during neoadjuvant cemiplimab therapy is associated with antitumor response

scientific article published on 05 January 2021

The Activation of MAPK in Melanoma Cells Resistant to BRAF Inhibition Promotes PD-L1 Expression That Is Reversible by MEK and PI3K Inhibition ⬇️

scientific article published on October 24, 2012

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

scientific article published on 09 February 2015

The Impact of Intratumoral and Gastrointestinal Microbiota on Systemic Cancer Therapy

scientific article published on 01 November 2018

The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy

scientific article published on 01 April 2018

The RNA-binding protein MEX3B mediates resistance to cancer immunotherapy by downregulating HLA-A expression

scientific article published in March 2018

The Rationale and Emerging Use of Neoadjuvant Immune Checkpoint Blockade for Solid Malignancies.

scientific article published on 2 March 2018

The Tumor Microbiome in Pancreatic Cancer: Bacteria and Beyond

scientific article published on 01 December 2019

The cancer microbiome

scientific article published on 11 June 2019

The gut microbiota influences anticancer immunosurveillance and general health

scientific article published on 10 April 2018

The human tumor microbiome is composed of tumor type-specific intracellular bacteria

scientific article

The immune microenvironment confers resistance to MAPK pathway inhibitors through macrophage-derived TNFα

scientific article

The microbiome, cancer, and cancer therapy

scientific article published on 06 March 2019

The need for a network to establish and validate predictive biomarkers in cancer immunotherapy

scientific article published on 3 November 2017

The role of the gastrointestinal microbiome in infectious complications during induction chemotherapy for acute myeloid leukemia.

scientific article

The state of melanoma: challenges and opportunities

scientific article

Toxicity of Immune Checkpoint Inhibitors: Considerations for the Surgeon

scientific article published on 21 January 2020

Tumor MHC Class I Expression Associates with Intralesional IL2 Response in Melanoma

scientific article published on 01 March 2022

Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

scientific article published on 01 August 2019

Tumor-associated B-cells induce tumor heterogeneity and therapy resistance

scientific article published on 19 September 2017

Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion ⬇️

scientific article (publication date: 26 July 2012)

Twenty-Three Years of the Warshaw Operation for Distal Pancreatectomy With Preservation of the Spleen ⬇️

scientific article published on June 1, 2011

Uncovering the role of the gut microbiota in immune checkpoint blockade therapy: A mini-review

scientific article published on 01 January 2020

Understanding hospital readmissions after pancreaticoduodenectomy: can we prevent them?: a 10-year contemporary experience with 1,173 patients at the Massachusetts General Hospital

scientific article published on 04 September 2013

Universes collide: combining immunotherapy with targeted therapy for cancer

scientific article

Update on use of aldesleukin for treatment of high-risk metastatic melanoma

scientific article published on 07 April 2015

Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations

scientific article

Utility of BRAF V600E Immunohistochemistry Expression Pattern as a Surrogate of BRAF Mutation Status in 154 Patients with Advanced Melanoma

scientific article published on 6 May 2015

Uveal melanoma: From diagnosis to treatment and the science in between

scientific article

VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

scientific article

Working with Human Tissues for Translational Cancer Research.

scientific article published on 26 November 2015

YAP in MAPK pathway targeted therapy resistance

scientific article

sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance

scientific article published on 4 April 2016

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