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List of works by Hengli Tang

A Conserved Tandem Cyclophilin-Binding Site in Hepatitis C Virus Nonstructural Protein 5A Regulates Alisporivir Susceptibility ⬇️

scientific article published on February 15, 2012

A major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approach

scientific article

Advances in Zika Virus Research: Stem Cell Models, Challenges, and Opportunities

scientific article (publication date: December 2016)

Aggregate formation and suspension culture of human pluripotent stem cells and differentiated progeny

scientific article published in December 2015

An hPSC-Derived Tissue-Resident Macrophage Model Reveals Differential Responses of Macrophages to ZIKV and DENV Infection

article

Apolipoprotein E mediates attachment of clinical hepatitis C virus to hepatocytes by binding to cell surface heparan sulfate proteoglycan receptors

scientific article published on 2 July 2013

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

scientific article

Castanospermine reduces Zika virus infection-associated seizure by inhibiting both the viral load and inflammation in mouse models

scientific article published on 16 September 2020

Cell death-inducing DFFA-like effector b is required for hepatitis C virus entry into hepatocytes

scientific article published on 14 May 2014

Cellular and molecular biology of HCV infection and hepatitis

scientific article published on 15 June 2009

Characterization of Hepatitis C Virus Subgenomic Replicon Resistance to Cyclosporine In Vitro

scientific article (publication date: June 2007)

Comparisons of RNAi approaches for validation of human RNA helicase A as an essential factor in hepatitis C virus replication

scientific article published on 30 September 2008

Critical Role of Cyclophilin A and Its Prolyl-Peptidyl Isomerase Activity in the Structure and Function of the Hepatitis C Virus Replication Complex

scientific article

Cyclophilin A Is an Essential Cofactor for Hepatitis C Virus Infection and the Principal Mediator of Cyclosporine Resistance In Vitro

scientific article (publication date: June 2008)

Cyclophilin Inhibitors as a Novel HCV Therapy ⬇️

scientific article published on August 5, 2010

Cyclophilins as modulators of viral replication

scientific article published on 11 July 2013

Cyclosporine Inhibits Flavivirus Replication through Blocking the Interaction between Host Cyclophilins and Viral NS5 Protein

scientific article (publication date: August 2009)

Design, synthesis and discovery of andrographolide derivatives against Zika virus infection

scientific article published on 30 November 2019

Development of bivalent oleanane-type triterpenes as potent HCV entry inhibitors

scientific article published on 7 March 2014

Effect of cell growth on hepatitis C virus (HCV) replication and a mechanism of cell confluence-based inhibition of HCV RNA and protein expression

scientific article

Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.

scientific article published on 5 June 2018

Hepatitis C Virus Attachment Mediated by Apolipoprotein E Binding to Cell Surface Heparan Sulfate ⬇️

scientific article published on April 24, 2012

Hepatitis C Virus-Induced Degradation of Cell Death-Inducing DFFA-Like Effector B Leads to Hepatic Lipid Dysregulation

scientific article published on 10 February 2016

High-Throughput Zika Viral Titer Assay for Rapid Screening of Antiviral Drugs

scientific article published on 01 April 2019

Identification of a common Ara h 3 epitope recognized by both the capture and the detection monoclonal antibodies in an ELISA detection kit.

scientific article published on 11 August 2017

Identification of cellular cofactors for human immunodeficiency virus replication via a ribozyme-based genomics approach

scientific article

Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

scientific article

Inhibition of zika virus infection by fused tricyclic derivatives of 1,2,4,5-tetrahydroimidazo[1,5-a]quinolin-3(3aH)-one

scientific article published on 01 September 2020

Intrinsic antiviral immunity of barrier cells revealed by an iPSC-derived blood-brain barrier cellular model

scientific article published in 2022

Massive-scale biological activity-based modeling identifies novel antiviral leads against SARS-CoV-2

scientific article published on 27 July 2020

Modeling Dengue Virus-Hepatic Cell Interactions Using Human Pluripotent Stem Cell-Derived Hepatocyte-like Cells

scientific article (publication date: 13 September 2016)

Molecular determinants of nucleolar translocation of RNA helicase A.

scientific article published on 14 August 2007

Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

scientific article

Multiplexed biomarker panels discriminate Zika and Dengue virus infection in humans

scientific article published on 15 November 2017

Mutations in the hepatitis C virus polymerase that increase RNA binding can confer resistance to cyclosporine A

scientific article

Novel technologies for studying virus-host interaction and discovering new drug targets for HCV and HIV.

scientific article

Productive hepatitis C virus infection of stem cell-derived hepatocytes reveals a critical transition to viral permissiveness during differentiation

scientific article

Racing to Uncover the Link between Zika Virus and Microcephaly

scientific article

Selection and characterization of drug-resistant HCV replicons in vitro with a flow cytometry-based assay

scientific article published on January 2009

Short-hairpin RNAs delivered by lentiviral vector transduction trigger RIG-I-mediated IFN activation

scientific article published on 03 September 2009

Simultaneous reduction and digestion of proteins with disulfide bonds for hydrogen/deuterium exchange monitored by mass spectrometry

scientific article

Suppression of viral RNA binding and the assembly of infectious hepatitis C virus particles in vitro by cyclophilin inhibitors

scientific article

The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function

scientific article

The Isomerase Active Site of Cyclophilin A Is Critical for Hepatitis C Virus Replication

scientific article

The interaction between claudin-1 and dengue viral prM/M protein for its entry

scientific article published on 7 September 2013

The missing pieces of the HCV entry puzzle

scientific article

Zika Says No Dice to Dicer

scientific article published on 01 October 2020

Zika Virus Infection Induces DNA Damage Response in Human Neural Progenitors That Enhances Viral Replication

scientific article published on 30 September 2019

Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

scientific article

Zika virus and neural developmental defects: building a case for a cause

scientific article

Zika virus directly infects peripheral neurons and induces cell death

scientific article published on 31 July 2017

Zika-Virus-Encoded NS2A Disrupts Mammalian Cortical Neurogenesis by Degrading Adherens Junction Proteins

scientific article published on 16 August 2017

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