List of works - Alain de Bruin

<i>H2AFZ</i>: A Novel Prognostic Marker in Canine Melanoma and a Predictive Marker for Resistance to CDK4/6 Inhibitor Treatment

scientific article published on 16 August 2021

A hypomorphic mutation in Lpin1 induces progressively improving neuropathy and lipodystrophy in the rat

scientific article

Atypical E2F repressors and activators coordinate placental development

scientific journal article

C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.

scientific article published on 14 June 2019

Chk1 and 14-3-3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest

scientific article

Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation

scientific journal article

Cyclin F-dependent degradation of E2F7 is critical for DNA repair and G2-phase progression

scientific article published on 02 September 2019

E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

scientific article published on 23 January 2020

E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1

scientific article

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression

scientific journal article

E2F8 is essential for polyploidization in mammalian cells

scientific journal article

Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease

scientific article published on 8 February 2016

Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation

scientific journal article

Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia

scientific article published on 12 April 2017

Molecular pathways of senescence regulate placental structure and function

scientific article published on 19 August 2019

Molecular pathways of senescence regulate placental structure and function

scientific article published on 01 August 2020

PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis

scientific article published on 23 November 2020

Par1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytes

scientific article

Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb -deficient mice ⬇️

scientific article published on May 5, 2003

The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism

scientific journal article

The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiency

scientific article published in 2014

List of works by Alain de Bruin

<i>H2AFZ</i>: A Novel Prognostic Marker in Canine Melanoma and a Predictive Marker for Resistance to CDK4/6 Inhibitor Treatment

A hypomorphic mutation in Lpin1 induces progressively improving neuropathy and lipodystrophy in the rat

Atypical E2F repressors and activators coordinate placental development

C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice.

Chk1 and 14-3-3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest

Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation

Cyclin F-dependent degradation of E2F7 is critical for DNA repair and G2-phase progression

E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression

E2F8 is essential for polyploidization in mammalian cells

Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease

Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation

Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia

Molecular pathways of senescence regulate placental structure and function

Molecular pathways of senescence regulate placental structure and function

PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis

Par1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytes

Rb function in extraembryonic lineages suppresses apoptosis in the CNS of Rb -deficient mice ⬇️

The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism

The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiency