List of works by Marlous Hoogstraat

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity.

scientific article

An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer

scientific article published on 06 September 2021

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer

scientific article

Comprehensive characterization of pre- and post-treatment samples of breast cancer reveal potential mechanisms of chemotherapy resistance

scientific article published on 06 May 2022

CopywriteR: DNA copy number detection from off-target sequence data

scientific article

Detailed imaging and genetic analysis reveal a secondary BRAF(L505H) resistance mutation and extensive intrapatient heterogeneity in metastatic BRAF mutant melanoma patients treated with vemurafenib

scientific article

Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence

scientific article published in 2022

Effective Therapeutic Intervention and Comprehensive Genetic Analysis of mTOR Signaling in PEComa: A Case Report.

scientific article published in June 2015

Enrichment of high-grade tumors in breast cancer gene expression studies

scientific article published on 18 December 2017

GPCR-SAS: A web application for statistical analyses on G protein-coupled receptors sequences

scientific article published in PLoS ONE

Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer.

scientific article published on 10 August 2015

Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer

scientific article published on 09 June 2022

Genomic and transcriptomic plasticity in treatment-naive ovarian cancer

scientific article

Long-term prognosis of young breast cancer patients (≤40 years) who did not receive adjuvant systemic treatment: protocol for the PARADIGM initiative cohort study.

scientific article published on 14 November 2017

Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages.

scientific article published on 19 June 2017

Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response

scientific article

Ovarian cancer cell line panel (OCCP): clinical importance of in vitro morphological subtypes

scientific article

PRI-CAT: a web-tool for the analysis, storage and visualization of plant ChIP-seq experiments

scientific article

Predicting clinical benefit from everolimus in patients with advanced solid tumors, the CPCT-03 study

scientific article

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases

scientific article

RUBIC identifies driver genes by detecting recurrent DNA copy number breaks

scientific article published on 11 July 2016

Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms

scientific article published on 20 March 2015

Simultaneous Detection of Clinically Relevant Mutations and Amplifications for Routine Cancer Pathology

scientific article published on 24 October 2014

TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition of mTORC1/2 and Bcl-2.

scientific article

Targeted next-generation sequencing: a novel diagnostic tool for primary immunodeficiencies.

scientific article published on 15 October 2013

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