Search filters

List of works by Alexander Zarbock

12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis

scientific article published on 12 August 2009

6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice.

scientific article

A novel type of macrothrombocytopenia associated with a defect in α2,3-sialylation

scientific article

ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistance

scientific article published on 11 January 2019

Actin dynamics in the regulation of endothelial barrier functions and neutrophil recruitment during endotoxemia and sepsis

scientific article published on 2 February 2017

Acute Kidney Injury and Information Technology

scientific article published on 23 January 2018

Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup

scientific article

Acute kidney injury - remote ischaemic preconditioning: a nephroprotective strategy?

scientific article

Acute loss of renal function attenuates slow leukocyte rolling and transmigration by interfering with intracellular signaling

scientific article

Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites ⬇️

scientific article published on May 31, 2011

Alarmin S100A8 Activates Alveolar Epithelial Cells in the Context of Acute Lung Injury in a TLR4-Dependent Manner

scientific article published on 13 November 2017

Alveolar macrophage activation is a key initiation signal for acute lung ischemia-reperfusion injury

scientific article

Annexin A1 counteracts chemokine-induced arterial myeloid cell recruitment

scientific article published on 17 December 2014

Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63.

scientific article published on 28 April 2014

Anti-inflammatory mechanisms and therapeutic opportunities in myocardial infarct healing

scientific article published on 07 January 2012

ArhGAP15, a RacGAP, Acts as a Temporal Signaling Regulator of Mac-1 Affinity in Sterile Inflammation

scientific article published on 27 July 2020

Biomarker-guided implementation of the KDIGO guidelines to reduce the occurrence of acute kidney injury in patients after cardiac surgery (PrevAKI-multicentre): protocol for a multicentre, observational study followed by randomised controlled feasib

scientific article published on 06 April 2020

Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus

scholarly article by Johanna Breuer et al published 22 August 2018 in Journal of Neuroinflammation

Blocking p21-activated kinase reduces lipopolysaccharide-induced acute lung injury by preventing polymorphonuclear leukocyte infiltration

scientific article

CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis

scientific article published on 17 May 2010

COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup

scientific article published on 15 October 2020

CXCR2: From Bench to Bedside

scientific article published on 24 August 2012

Cardiac and Vascular Surgery-Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group.

scientific article

Cardiopulmonary bypass during cardiac surgery modulates systemic inflammation by affecting different steps of the leukocyte recruitment cascade

scientific article

Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment

scientific article published on 22 September 2016

Chapter 11. Intravital microscopic investigation of leukocyte interactions with the blood vessel wall

scientific article

Clinical use of [TIMP-2]•[IGFBP7] biomarker testing to assess risk of acute kidney injury in critical care: guidance from an expert panel.

scientific article

Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation

scientific article

Coordinated and unique functions of the E-selectin ligand ESL-1 during inflammatory and hematopoietic recruitment in mice

scientific article

Correction: Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease

scientific article published on 20 February 2018

Cortactin deficiency is associated with reduced neutrophil recruitment but increased vascular permeability in vivo

scientific article

Cross-Talk between Shp1 and PIPKIγ Controls Leukocyte Recruitment

scientific article

Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury ⬇️

scientific article published on January 30, 2012

Directed transport of neutrophil-derived extracellular vesicles enables platelet-mediated innate immune response

scientific article

Discussion on "Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial".

scientific article published on 9 January 2018

Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo

scientific article

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation ⬇️

scientific article published on March 19, 2012

Dual action by fumaric acid esters synergistically reduces adhesion to human endothelium

scientific article

Early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury (The ELAIN-Trial): study protocol for a randomized controlled trial

scientific article published on 18 March 2016

Echophysiology: the transesophageal echo probe as a noninvasive Swan-Ganz catheter

scientific article

Editorial: Hematopoietic cell function—a matter of age ⬇️

scientific article published on February 1, 2013

Editorial: goal-directed hemodynamic monitoring is the key prerequisite for goal-directed therapy

scientific article published on 9 December 2015

Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury: The ELAIN Randomized Clinical Trial

scientific article published on 22 May 2016

Effect of remote ischemic preconditioning on kidney injury among high-risk patients undergoing cardiac surgery: a randomized clinical trial

scientific article

Eliminating or blocking 12/15-lipoxygenase reduces neutrophil recruitment in mouse models of acute lung injury ⬇️

scientific article published on September 13, 2012

Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice

scientific article

Endothelial cell-derived CD95 ligand serves as a chemokine in induction of neutrophil slow rolling and adhesion

scientific article (publication date: 20 October 2016)

Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.

scientific article

Erratum to: 'Early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury (The ELAIN-Trial): study protocol for a randomized controlled trial'.

scientific article published on 23 May 2016

Erratum to: Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial.

scientific article

Event-tracking model of adhesion identifies load-bearing bonds in rolling leukocytes

scientific article

FGF23 signaling impairs neutrophil recruitment and host defense during CKD.

scientific article

Fibroblast growth factor 23 actions in inflammation: a key factor in CKD outcomes

scientific article published on 22 September 2016

From lung injury to fibrosis

scientific article published in January 2008

Galphai2 is required for chemokine-induced neutrophil arrest

scientific article

Gnb isoforms control a signaling pathway comprising Rac1, Plcβ2, and Plcβ3 leading to LFA-1 activation and neutrophil arrest in vivo

scientific article

Hold on to your endothelium: postarrest steps of the leukocyte adhesion cascade

scientific article

IL-17A inhibits the expansion of IL-17A-producing T cells in mice through "short-loop" inhibition via IL-17 receptor

scientific article

IL-23 is required for neutrophil homeostasis in normal and neutrophilic mice

scientific article

IL-4 enhances hypoxia induced HIF-1alpha protein levels in human transformed intestinal cells

scientific article published on 3 November 2006

Improve hip fracture outcome in the elderly patient (iHOPE): a study protocol for a pragmatic, multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia

article published in 2018

Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI).

scientific article

Inflammatory response and extracorporeal circulation

scientific article published on 27 March 2015

Inhibitors of CXC chemokine receptor type 4: putative therapeutic approaches in inflammatory diseases

scientific article

Initiation of protein O glycosylation by the polypeptide GalNAcT-1 in vascular biology and humoral immunity

scientific article

Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin

scientific article

Ischemia-reperfusion injury and anesthesia

scientific article published on 19 June 2014

Leukocyte Function Antigen-1, Kindlin-3, and Calcium Flux Orchestrate Neutrophil Recruitment during Inflammation ⬇️

scientific article published on November 9, 2012

Leukocyte integrin activation and deactivation: novel mechanisms of balancing inflammation

scientific article

Lidocaine reduces neutrophil recruitment by abolishing chemokine-induced arrest and transendothelial migration in septic patients

scientific article published on 29 November 2013

Long-Term Clinical Outcomes after Early Initiation of RRT in Critically Ill Patients with AKI.

scientific article published in December 2017

Long-term Effects of Remote Ischemic Preconditioning on Kidney Function in High-risk Cardiac Surgery Patients: Follow-up Results from the RenalRIP Trial

scientific article

Loss of cortactin causes endothelial barrier dysfunction via disturbed adrenomedullin secretion and actomyosin contractility

scientific article published on 30 June 2016

L‐selectin shedding by NSAIDs: Old friends in new dresses ⬇️

scientific article published on January 1, 2013

Management of right ventricular dysfunction in the perioperative setting

scientific article published on August 2014

Mechanisms and consequences of neutrophil interaction with the endothelium

scientific article

Mutation in the CD45 inhibitory wedge modulates integrin activation and leukocyte recruitment during inflammation

scientific article published on 10 December 2014

Neutrophil adhesion and activation under flow

scientific article

New insights into leukocyte recruitment by intravital microscopy

scientific article published on January 2009

Novel therapy for renal protection

scientific article published on August 2015

Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II.

scientific article published in June 2018

PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling

scientific article

PSGL-1-dependent myeloid leukocyte activation

scientific article published on 07 August 2009

Pathogenesis of Multiple Organ Failure in Sepsis

scientific article

Patient with chronic renal failure undergoing surgery

scientific article published on 4 March 2016

Perioperative Acute Kidney Injury: An Under-recognized Problem

scientific article published on 4 August 2017

Perioperative Inflammation and Its Modulation by Anesthetics

scientific article published on 14 September 2017

Platelet-neutrophil-interactions: linking hemostasis and inflammation

scientific article

Platelets as autonomous drones for hemostatic and immune surveillance

scientific article

Platelets in Inflammation and Resolution

scientific article published on 01 November 2019

Platelets in leucocyte recruitment and function

scientific article

Prevention of acute kidney injury

scientific article published on 18 August 2017

Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial

scientific article published on 21 January 2017

Prevention of cardiac surgery-associated acute kidney injury

scientific article published on 20 September 2016

Protein tyrosine kinases in neutrophil activation and recruitment ⬇️

scientific article published on February 19, 2011

Publisher Correction: COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup

scientific article published on 02 November 2020

Quality Improvement Goals for Acute Kidney Injury

scientific article published on 17 May 2019

Rap1a activation by CalDAG‐GEFI and p38 MAPK is involved in E‐selectin‐dependent slow leukocyte rolling ⬇️

scientific article published on June 7, 2011

Recommendations on Acute Kidney Injury Biomarkers From the Acute Disease Quality Initiative Consensus Conference: A Consensus Statement

scientific article published on 01 October 2020

Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung

scientific article

Remote Ischemic Preconditioning and Protection of the Kidney--A Novel Therapeutic Option

scientific article

Remote ischemic preconditioning and outcome: shall we all have an intermittent tourniquet?

scientific article

Renal Replacement Therapy in Acute Kidney Injury - Indication and Implementation

scientific article published on 9 February 2018

Renal biomarkers for the initiation of renal replacement therapy-is this the future?

Renal protection in the 21st century

scientific article published on December 2016

Renal replacement therapy in critically ill patients: who, when, why, and how.

scientific article

Renoprotection by remote ischemic conditioning during elective coronary revascularization: A systematic review and meta-analysis of randomized controlled trials

scientific article

Risks associated with peripherally inserted central catheters

scientific article

Rolling on E- or P-selectin induces the extended but not high-affinity conformation of LFA-1 in neutrophils

scientific article

STIMulation of signaling in neutrophils.

scientific article

Second consensus on the assessment of sublingual microcirculation in critically ill patients: results from a task force of the European Society of Intensive Care Medicine

scientific article published on 6 February 2018

Sepsis-induced acute kidney injury revisited: pathophysiology, prevention and future therapies

scientific article

Severe Impairment of Leukocyte Recruitment in ppGalNAcT-1–Deficient Mice ⬇️

scientific article published on April 27, 2012

Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation

scientific article

Skap2 is required for β2 integrin-mediated neutrophil recruitment and functions

scientific article published on 9 February 2017

Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1.

scientific article

Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability

scientific article

Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap-mediated sterile inflammation

scientific article published on 12 December 2013

T cells modulate neutrophil-dependent acute renal failure during endotoxemia: critical role for CD28.

scientific article published on 2 February 2005

T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo

scientific article

The Bruton's tyrosine kinase inhibitor PRN473 inhibits neutrophil recruitment via inhibition of Mac-1 signaling.

scientific article published on 11 November 2017

The European Society of Anaesthesiology research support programme at 15 years: a lot done, still more to do.

scientific article published in December 2017

The ITIM Domain–Containing NK Receptor Ly49Q Impacts Pulmonary Infection by Mediating Neutrophil Functions

scientific article published on 30 April 2018

The Neutrophil Btk Signalosome Regulates Integrin Activation during Sterile Inflammation

scientific article published on 04 January 2016

The New World Health Organization Recommendations on Perioperative Administration of Oxygen to Prevent Surgical Site Infections: A Dangerous Reductionist Approach?

scientific article published on 4 July 2017

The PSGL-1-L-selectin signaling complex regulates neutrophil adhesion under flow

scientific article

The Role of the Tec Kinase Bruton's Tyrosine Kinase (Btk) in Leukocyte Recruitment ⬇️

scientific article published on April 1, 2012

The intensive care medicine agenda on acute kidney injury

scientific article published on 30 January 2017

The plexin C1 receptor promotes acute inflammation

scientific article published on 30 June 2014

The role for decorin in delayed-type hypersensitivity

scientific article published on 31 October 2011

The role of kindlin in neutrophil recruitment to inflammatory sites

scientific article

The role of platelets in acute lung injury (ALI)

scientific article

Thoracic epidural anesthesia time-dependently modulates pulmonary endothelial dysfunction in septic rats

scientific article

Timing of renal replacement therapy in acute kidney injury-an issue of importance?

scientific article published on September 2016

Timing of renal replacement therapy in critically ill patients with acute kidney injury

scientific article published on September 2016

Tissue-Specific Neutrophil Recruitment into the Lung, Liver, and Kidney ⬇️

scientific article published on December 21, 2012

Urinary TIMP-2 and IGFBP7 as early biomarkers of acute kidney injury and renal recovery following cardiac surgery

scientific article

VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells

scientific article published on 18 August 2014

Validation of cell-cycle arrest biomarkers for acute kidney injury after pediatric cardiac surgery

scientific article

What endpoints should be used for clinical studies in acute kidney injury?

scientific article

β2-integrin activity: the role of thiols ⬇️

scientific article published on May 9, 2013

Paulina is supported by:

About Paulina

Help