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List of works by Friedemann Kiefer

A novel family of fluorescent hypoxia sensors reveal strong heterogeneity in tumor hypoxia at the cellular level

scientific article published on 23 November 2015

A novel model for ectopic, chronic, intravital multiphoton imaging of bone marrow vasculature and architecture in split femurs

scientific article published on May 2015

A qualitative comparison of ten tissue clearing techniques

scientific article published on 12 May 2017

Activation of hematopoietic progenitor kinase 1 involves relocation, autophosphorylation, and transphosphorylation by protein kinase D1.

scientific article published on March 2005

Activation or suppression of NFkappaB by HPK1 determines sensitivity to activation-induced cell death

scientific article published on 8 December 2005

Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state

scientific article published on 22 June 2012

An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation

scientific article

B cell adaptor containing src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1

scientific article

CCR7-mediated LFA-1 functions in T cells are regulated by 2 independent ADAP/SKAP55 modules

scientific article published on 23 November 2011

Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes

scientific article published on 21 August 2007

Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB

scientific article published on 29 January 2001

Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2.

scientific article

Cx47 fine-tunes the handling of serum lipids but is dispensable for lymphatic vascular function

scientific article published on 21 July 2017

Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

scientific article published on 19 April 2021

Distinct roles of VE-cadherin for development and maintenance of specific lymph vessel beds

article

Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion

scientific journal article

Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases.

scientific article published on February 1994

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature

scientific article

Fusing VE-cadherin to α-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation

scientific article

Generation of completely embryonic stem cell-derived mutant mice using tetraploid blastocyst injection

scientific article published in March 1997

HPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion

scientific article

HPK1 competes with ADAP for SLP-76 binding and via Rap1 negatively affects T-cell adhesion.

scientific article

HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.

scientific article published on April 2000

Hematopoietic progenitor kinase 1 (HPK1) is required for LFA-1-mediated neutrophil recruitment during the acute inflammatory response

scientific article

Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response

scientific article published on 29 September 2009

Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation

scientific article published in May 2009

Identification of a clonally expanding haematopoietic compartment in bone marrow

scientific article published on 27 November 2012

Intravital two-photon microscopy of lymphatic vessel development and function using a transgenic Prox1 promoter-directed mOrange2 reporter mouse

scientific article published on December 2011

Introductory remarks

scientific article published on 01 January 2014

Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program.

scientific article published on 17 April 2018

Maturation of Platelet Function During Murine Fetal Development In Vivo.

scientific article

Mechanotransduction, PROX1, and FOXC2 cooperate to control connexin37 and calcineurin during lymphatic-valve formation

scientific article published on 2 February 2012

Migration inhibition of mammary epithelial cells by Syk is blocked in the presence of DDR1 receptors

scientific article published on 17 April 2011

Modulation of synaptic function through the α-neurexin-specific ligand neurexophilin-1.

scientific article published on 17 March 2014

Multiple roles of lymphatic vessels in peripheral lymph node development

article

Novel components of mammalian stress-activated protein kinase cascades

scientific article published on May 1997

Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells

scholarly article

Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development

scientific article

Rapid methods for the evaluation of fluorescent reporters in tissue clearing and the segmentation of large vascular structures

scientific article published on 26 May 2021

Receptor tyrosine kinase inhibitors: Are they real tumor killers?

scientific article published on 25 February 2015

Regulation of developmental lymphangiogenesis by Syk(+) leukocytes

scientific article

SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1

scientific article

ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation

scientific article

Signal transduction and co-stimulatory pathways

scientific article

Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability

scientific article

Statistical Permutation-based Artery Mapping (SPAM): a novel approach to evaluate imaging signals in the vessel wall.

scientific article published on 26 May 2017

Suboptimal B-cell antigen receptor signaling activity in vivo elicits germinal center counterselection mechanisms.

scientific article published on 2 December 2014

Sustained JNK signaling by proteolytically processed HPK1 mediates IL-3 independent survival during monocytic differentiation.

scientific article

Synergistic regulation of immunoreceptor signaling by SLP-76-related adaptor Clnk and serine/threonine protein kinase HPK-1.

scientific article

Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization

scientific article

The BAFFling function of Syk in B-cell homeostasis

scientific article published on 20 February 2015

The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction

scientific article

The guanine nucleotide exchange factor Arhgef7/βPix promotes axon formation upstream of TC10.

scientific article published on 11 June 2018

The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis

scientific article published on 27 May 2015

The junctional adhesion molecule (JAM) family members JAM-2 and JAM-3 associate with the cell polarity protein PAR-3: a possible role for JAMs in endothelial cell polarity

scientific article (publication date: October 2003)

The role of chemokines and their receptors in angiogenesis

scientific article published on 09 April 2011

The role of fatty acid β-oxidation in lymphangiogenesis

scientific article published on 26 December 2016

Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy

scientific article published on 16 January 2014

Tissue clearing may alter emission and absorption properties of common fluorophores

scientific article published on 01 April 2022

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

scientific article published on 7 March 2016

Unperturbed Immune Function despite Mutation of C-Terminal Tyrosines in Syk Previously Implicated in Signaling and Activity Regulation

scientific article published on 31 July 2017

VE-PTP controls blood vessel development by balancing Tie-2 activity

scientific article

VIPAR, a quantitative approach to 3D histopathology applied to lymphatic malformations

scientific article

Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities

scientific article published on 20 September 2021

Visualization of lymphatic vessel development, growth, and function

scientific article published on January 2014

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