Search filters

List of works by Stefan Legewie

A mesoscale model of G1/S phase transition in liver regeneration

scientific article published in February 2008

A minimal circadian clock model.

scientific article published on January 2007

A multi-scale model of hepcidin promoter regulation reveals factors controlling systemic iron homeostasis

scientific article

A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts

scientific article published on 12 January 2009

Atypical protein kinase C zeta exhibits a proapoptotic function in ovarian cancer.

scientific article

Caspase-8 activity has an essential role in CD95/Fas-mediated MAPK activation

scientific article published on 6 October 2011

Cell-specific responses to the cytokine TGFβ are determined by variability in protein levels

scientific article published on 25 January 2018

Competing docking interactions can bring about bistability in the MAPK cascade

scientific article published on 25 May 2007

Correction: Multi-Target Regulation by Small RNAs Synchronizes Gene Expression Thresholds and May Enhance Ultrasensitive Behavior

scientific article published in PLoS ONE

Correlated receptor transport processes buffer single-cell heterogeneity

scientific article published on 25 September 2017

Determinants of cell-to-cell variability in protein kinase signaling

scientific article

Effects of sequestration on signal transduction cascades

scientific article published in March 2006

Estrogen-dependent control and cell-to-cell variability of transcriptional bursting.

scientific article published on 23 February 2018

High-throughput mutagenesis identifies mutations and RNA-binding proteins controlling CD19 splicing and CART-19 therapy resistance

scientific article published in 2022

Identifying Novel Transcriptional Regulators with Circadian Expression

scientific article published on 07 December 2015

Intra- and interdimeric caspase-8 self-cleavage controls strength and timing of CD95-induced apoptosis

scientific article

Kinetic mechanisms for overexpression insensitivity and oncogene cooperation.

scientific article published on 4 December 2008

Mathematical modeling identifies inhibitors of apoptosis as mediators of positive feedback and bistability

scientific article

Modelling Systemic Iron Regulation during Dietary Iron Overload and Acute Inflammation: Role of Hepcidin-Independent Mechanisms

scientific article

Multi-target regulation by small RNAs synchronizes gene expression thresholds and may enhance ultrasensitive behavior

scientific article

Multiparametric image analysis reveals role of Caveolin1 in endosomal progression rather than internalization of EGFR.

scientific article

Negative feedback in the bone morphogenetic protein 4 (BMP4) synexpression group governs its dynamic signaling range and canalizes development

scientific article

Quantitative analysis of ultrasensitive responses

scientific article published on August 2005

Recurrent design patterns in the feedback regulation of the mammalian signalling network

scientific article published on 6 May 2008

Reverse engineering a hierarchical regulatory network downstream of oncogenic KRAS.

scientific article

Robust Ordering of Anaphase Events by Adaptive Thresholds and Competing Degradation Pathways.

scientific article

Robustness of signal transduction pathways ⬇️

scientific article published on September 25, 2012

Silence on the relevant literature and errors in implementation

scientific article published in April 2015

Small RNAs establish delays and temporal thresholds in gene expression

scientific article

Systems analysis of MAPK signal transduction.

scientific article published on January 2008

Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.

scientific article published on 07 April 2009

Ultrasensitization: switch-like regulation of cellular signaling by transcriptional induction

scientific article

Paulina is supported by:

About Paulina

Help