List of works - Marilisa Leone

A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles

scholarly article in RSC Advances, vol. 5 no. 37, 2015

A structure-based approach to retinoid X receptor-alpha inhibition.

scientific article published on 10 April 2006

CD and NMR conformational studies of a peptide encompassing the Mid Loop interface of Ship2-Sam.

scientific article

Chemical modifications of peptide sequences via S-alkylation reaction

scientific article

Conformational ensembles explored dynamically from disordered peptides targeting chemokine receptor CXCR4.

scientific article

Design and NMR studies of cyclic peptides targeting the N-terminal domain of the protein tyrosine phosphatase YopH.

scientific article published on 30 November 2010

Design and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool.

scientific article

Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins

scientific article published on September 2003

Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process

scientific article

Exploring the Ability of Cyclic Peptides to Target SAM Domains: A Computational and Experimental Study

scientific article published on 26 November 2019

G-quadruplex DNA recognition by nucleophosmin: new insights from protein dissection.

scientific article

Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting.

scientific article

Heterotypic Sam-Sam association between Odin-Sam1 and Arap3-Sam: binding affinity and structural insights

scientific article published on 13 December 2012

High-Throughput Screening (HTS) by NMR Guided Identification of Novel Agents Targeting the Protein Docking Domain of YopH.

scientific article published on 23 November 2015

Intrinsically disordered amphiphilic peptides as potential targets in drug delivery vehicles

scientific article published on 01 November 2015

Lipidated peptides via post-synthetic thioalkylation promoted by molecular sieves

scientific article published on 20 April 2014

NMR Studies of a Heterotypic Sam−Sam Domain Association: The Interaction between the Lipid Phosphatase Ship2 and the EphA2 Receptor † , ‡

scientific article

NMR assignment of the phosphotyrosine binding (PTB) domain of tensin

scientific article published on 17 May 2006

NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein

scientific article (publication date: 3 March 2003)

NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH.

scientific article

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells

scientific article

Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions

scientific article

Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam

scientific article

Peptides targeting chemokine receptor CXCR4: structural behavior and biological binding studies

scientific article published on 28 January 2014

Postsynthetic Modification of Peptides via Chemoselective N-Alkylation of Their Side Chains

scientific article published on 12 March 2012

Selective incorporation of 19F-labeled Trp side chains for NMR-spectroscopy-based ligand-protein interaction studies.

scientific article

Self-assembly of PEGylated tetra-phenylalanine derivatives: structural insights from solution and solid state studies

scientific article

Solid-Phase S-Alkylation Promoted by Molecular Sieves

scientific article published on 02 November 2015

Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor

scientific article

Solution conformational features and interfacial properties of an intrinsically disordered peptide coupled to alkyl chains: a new class of peptide amphiphiles

scientific article published on 13 March 2013

Solution structure and backbone dynamics of the K18G/R82E Alicyclobacillus acidocaldarius thioredoxin mutant: a molecular analysis of its reduced thermal stability

scientific article published in May 2004

Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex

scientific article

Structural insights into and activity analysis of the antimicrobial peptide myxinidin.

scientific article published on 23 June 2014

Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site

scientific article

Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish

scientific article published on 03 September 2013

Structure-activity relationships by interligand NOE-based design and synthesis of antiapoptotic compounds targeting Bid.

scholarly article

Structure-based discovery of a new class of Bcl-xL antagonists.

scientific article published on 21 May 2007

Targeting apoptosis via chemical design: inhibition of bid-induced cell death by small organic molecules.

scientific article published on August 2004

The FRB domain of mTOR: NMR solution structure and inhibitor design

scientific article

The Nuclear Overhauser Effect in the lead identification process

scientific article published on June 2006

The PTB domain of tensin: NMR solution structure and phosphoinositides binding studies

scientific article

The Sam domain of the lipid phosphatase Ship2 adopts a common model to interact with Arap3-Sam and EphA2-Sam

scientific article

Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys₂ His₂ zinc finger induces structural rearrangements of typical DNA base determinant positions

scientific article

List of works by Marilisa Leone

A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles

A structure-based approach to retinoid X receptor-alpha inhibition.

CD and NMR conformational studies of a peptide encompassing the Mid Loop interface of Ship2-Sam.

Chemical modifications of peptide sequences via S-alkylation reaction

Conformational ensembles explored dynamically from disordered peptides targeting chemokine receptor CXCR4.

Design and NMR studies of cyclic peptides targeting the N-terminal domain of the protein tyrosine phosphatase YopH.

Design and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool.

Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins

Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process

Exploring the Ability of Cyclic Peptides to Target SAM Domains: A Computational and Experimental Study

G-quadruplex DNA recognition by nucleophosmin: new insights from protein dissection.

Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting.

Heterotypic Sam-Sam association between Odin-Sam1 and Arap3-Sam: binding affinity and structural insights

High-Throughput Screening (HTS) by NMR Guided Identification of Novel Agents Targeting the Protein Docking Domain of YopH.

Intrinsically disordered amphiphilic peptides as potential targets in drug delivery vehicles

Lipidated peptides via post-synthetic thioalkylation promoted by molecular sieves

NMR Studies of a Heterotypic Sam−Sam Domain Association: The Interaction between the Lipid Phosphatase Ship2 and the EphA2 Receptor † , ‡

NMR assignment of the phosphotyrosine binding (PTB) domain of tensin

NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein

NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH.

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells

Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions

Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam

Peptides targeting chemokine receptor CXCR4: structural behavior and biological binding studies

Postsynthetic Modification of Peptides via Chemoselective N-Alkylation of Their Side Chains

Selective incorporation of 19F-labeled Trp side chains for NMR-spectroscopy-based ligand-protein interaction studies.

Self-assembly of PEGylated tetra-phenylalanine derivatives: structural insights from solution and solid state studies

Solid-Phase S-Alkylation Promoted by Molecular Sieves

Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor

Solution conformational features and interfacial properties of an intrinsically disordered peptide coupled to alkyl chains: a new class of peptide amphiphiles

Solution structure and backbone dynamics of the K18G/R82E Alicyclobacillus acidocaldarius thioredoxin mutant: a molecular analysis of its reduced thermal stability

Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex

Structural insights into and activity analysis of the antimicrobial peptide myxinidin.

Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site

Structure-activity relations of myxinidin, an antibacterial peptide derived from the epidermal mucus of hagfish

Structure-activity relationships by interligand NOE-based design and synthesis of antiapoptotic compounds targeting Bid.

Structure-based discovery of a new class of Bcl-xL antagonists.

Targeting apoptosis via chemical design: inhibition of bid-induced cell death by small organic molecules.

The FRB domain of mTOR: NMR solution structure and inhibitor design

The Nuclear Overhauser Effect in the lead identification process

The PTB domain of tensin: NMR solution structure and phosphoinositides binding studies

The Sam domain of the lipid phosphatase Ship2 adopts a common model to interact with Arap3-Sam and EphA2-Sam

Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys₂ His₂ zinc finger induces structural rearrangements of typical DNA base determinant positions