List of works - Jean-Marc Egly

A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription

scientific article

A TBP-containing multiprotein complex (TIF-IB) mediates transcription specificity of murine RNA polymerase I

scientific article

A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A

scientific article

A yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIH

scientific article

Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7

scientific article (publication date: July 2000)

Both XPD alleles contribute to the phenotype of compound heterozygote xeroderma pigmentosum patients

scientific article

Cloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicases

scientific article

Cockayne syndrome B protein regulates the transcriptional program after UV irradiation

scientific article

DNA damage stabilizes interaction of CSB with the transcription elongation machinery

scientific article published on 28 June 2004

Design and development of a robotized system coupled to µCT imaging for intratumoral drug evaluation in a HCC mouse model

scientific article

Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activities

scientific article

Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair

scientific article

Dynamic partnership between TFIIH, PGC-1α and SIRT1 is impaired in trichothiodystrophy

scientific article

Dysregulation of the peroxisome proliferator-activated receptor target genes by XPD mutations

scientific article

Genomic organization and promoter characterization of two human UHS keratin genes

scientific article

Genomic structure of the putative BTF3 transcription factor

scientific article (publication date: 15 August 1992)

In TFIIH, XPD helicase is exclusively devoted to DNA repair

scientific article

Initiation of DNA repair mediated by a stalled RNA polymerase IIO.

scientific article published on 12 January 2006

Interacting partners of the Tfb2 subunit from yeast TFIIH.

scientific article

Mechanics of the IL2RA gene activation revealed by modeling and atomic force microscopy

scientific article (publication date: 2011)

Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH

scientific article

Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH

scientific journal article

New functions of XPC in the protection of human skin cells from oxidative damage

scientific article

Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK

scientific article

Ordered conformational changes in damaged DNA induced by nucleotide excision repair factors

scientific article published on 23 February 2004

Phosphorylation in transcription: the CTD and more

scientific article

Promoter of FGF8 reveals a unique regulation by unliganded RARalpha

scientific article (publication date: 7 June 2002)

Promoters of ASCL1- and NEUROD1-dependent genes are specific targets of lurbinectedin in SCLC cells

scientific article published on 09 March 2022

Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles

scientific article

Sequencing and expression of complementary DNA for the general transcription factor BTF3

scholarly article

Sequential and ordered assembly of a large DNA repair complex on undamaged chromatin

scientific article

Solution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophy

scientific article

Solution structure of the N-terminal domain of the human TFIIH MAT1 subunit: new insights into the RING finger family

scientific article

Structural basis for group A trichothiodystrophy

scientific article

Sublimiting concentration of TFIIH transcription/DNA repair factor causes TTD-A trichothiodystrophy disorder

scientific article (publication date: November 2000)

TFIIH enzymatic activities in transcription and nucleotide excision repair

scientific article

TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription

scientific article (publication date: 30 November 2001)

TFIIH-dependent MMP-1 overexpression in trichothiodystrophy leads to extracellular matrix alterations in patient skin

scientific article

The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor

scientific article

The FBP interacting repressor targets TFIIH to inhibit activated transcription

scientific article (publication date: February 2000)

The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor

scientific article

The comings and goings of nucleotide excision repair factors on damaged DNA

scientific article

The crystal structure of human cyclin H

scientific article

The gene encoding p44, a subunit of the transcription factor TFIIH, is involved in large-scale deletions associated with Werdnig-Hoffmann disease

scientific article

The human DNA repair factor XPC-HR23B distinguishes stereoisomeric benzo[a]pyrenyl-DNA lesions

scientific article (publication date: 20 June 2007)

The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process

scientific article

Trichothiodystrophy, a transcription syndrome

scientific article

True lies: the double life of the nucleotide excision repair factors in transcription and DNA repair

scientific article

p53 modulation of TFIIH–associated nucleotide excision repair activity ⬇️

scientific article published on June 1, 1995

p8/TTD-A as a repair-specific TFIIH subunit

scientific article published in January 2006

List of works by Jean-Marc Egly

A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription

A TBP-containing multiprotein complex (TIF-IB) mediates transcription specificity of murine RNA polymerase I

A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A

A yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIH

Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7

Both XPD alleles contribute to the phenotype of compound heterozygote xeroderma pigmentosum patients

Cloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicases

Cockayne syndrome B protein regulates the transcriptional program after UV irradiation

DNA damage stabilizes interaction of CSB with the transcription elongation machinery

Design and development of a robotized system coupled to µCT imaging for intratumoral drug evaluation in a HCC mouse model

Distinct regions of MAT1 regulate cdk7 kinase and TFIIH transcription activities

Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair

Dynamic partnership between TFIIH, PGC-1α and SIRT1 is impaired in trichothiodystrophy

Dysregulation of the peroxisome proliferator-activated receptor target genes by XPD mutations

Genomic organization and promoter characterization of two human UHS keratin genes

Genomic structure of the putative BTF3 transcription factor

In TFIIH, XPD helicase is exclusively devoted to DNA repair

Initiation of DNA repair mediated by a stalled RNA polymerase IIO.

Interacting partners of the Tfb2 subunit from yeast TFIIH.

Mechanics of the IL2RA gene activation revealed by modeling and atomic force microscopy

Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH

Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH

New functions of XPC in the protection of human skin cells from oxidative damage

Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK

Ordered conformational changes in damaged DNA induced by nucleotide excision repair factors

Phosphorylation in transcription: the CTD and more

Promoter of FGF8 reveals a unique regulation by unliganded RARalpha

Promoters of ASCL1- and NEUROD1-dependent genes are specific targets of lurbinectedin in SCLC cells

Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles

Sequencing and expression of complementary DNA for the general transcription factor BTF3

Sequential and ordered assembly of a large DNA repair complex on undamaged chromatin

Solution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophy

Solution structure of the N-terminal domain of the human TFIIH MAT1 subunit: new insights into the RING finger family

Structural basis for group A trichothiodystrophy

Sublimiting concentration of TFIIH transcription/DNA repair factor causes TTD-A trichothiodystrophy disorder

TFIIH enzymatic activities in transcription and nucleotide excision repair

TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription

TFIIH-dependent MMP-1 overexpression in trichothiodystrophy leads to extracellular matrix alterations in patient skin

The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor

The FBP interacting repressor targets TFIIH to inhibit activated transcription

The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor

The comings and goings of nucleotide excision repair factors on damaged DNA

The crystal structure of human cyclin H

The gene encoding p44, a subunit of the transcription factor TFIIH, is involved in large-scale deletions associated with Werdnig-Hoffmann disease

The human DNA repair factor XPC-HR23B distinguishes stereoisomeric benzo[a]pyrenyl-DNA lesions

The phosphorylation of the androgen receptor by TFIIH directs the ubiquitin/proteasome process

Trichothiodystrophy, a transcription syndrome

True lies: the double life of the nucleotide excision repair factors in transcription and DNA repair

p53 modulation of TFIIH–associated nucleotide excision repair activity ⬇️

p8/TTD-A as a repair-specific TFIIH subunit