List of works by Jacques Thèze

A programmed switch from IL-15- to IL-2-dependent activation in human NK cells.

scientific article published in May 2009

Altered responses to homeostatic cytokines in patients with idiopathic CD4 lymphocytopenia

scientific article

Analysis of the mechanisms of human cytotoxic T lymphocyte response inhibition by NO.

scientific article published in October 2002

Anti-retroviral therapy in HIV-infected patients: in vitro effects of AZT and saquinavir on the response of CD4 and CD8 lymphocytes to interleukin-7.

scientific article published in December 2005

Characteristics of plasmacytoid dendritic cell and CD4+ T cell in HIV elite controllers

scientific article

Characterization of a monoclonal antibody directed against the NH2 terminal area of interleukin-2 (IL-2) and inhibiting specifically the binding of IL-2 to IL-2 receptor beta chain (IL-2R beta).

scientific article

Characterization of an IL-2 mimetic with therapeutic potential

scientific article

Constitutive expression of IL-2Rbeta chain and its effects on IL-2-induced vascular leak syndrome

scientific article published on 27 December 2005

Correction: Membrane microdomains and cytoskeleton organization shape and regulate the IL-7 receptor signalosome in human CD4 T-cells

scientific article published in 2019

Defective interleukin-2-dependent STAT5 signalling in CD8 T lymphocytes from HIV-positive patients: restoration by antiretroviral therapy.

scientific article

Disruption of the gamma c cytokine network in T cells during HIV infection

scientific article published on 15 April 2008

Dual mechanism of impairment of interleukin-7 (IL-7) responses in human immunodeficiency virus infection: decreased IL-7 binding and abnormal activation of the JAK/STAT5 pathway

scientific article published on January 2010

Efficacy of Rifampin-Moxifloxacin-Metronidazole Combination Therapy in Hidradenitis Suppurativa ⬇️

scientific article published on November 25, 2010

HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity

scientific article

HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term.

scientific article published on 25 July 2012

HIV controllers: a multifactorial phenotype of spontaneous viral suppression

scientific article published on 04 August 2011

HIV infection impairs CCR7-dependent T-cell chemotaxis independent of CCR7 expression.

scientific article

HIV infection perturbs interleukin-7 signaling at the step of STAT5 nuclear relocalization

scientific article

HIV infection: pre-highly active antiretroviral therapy IL-7 plasma levels correlate with long-term CD4 cell count increase after treatment

scientific article

Human IL-Rbeta chains form IL-2 binding homodimers

scientific article published on 26 February 2008

IL-2 Induces Conformational Changes in Its Preassembled Receptor Core, Which Then Migrates in Lipid Raft and Binds to the Cytoskeleton Meshwork ⬇️

scientific article published on September 21, 2010

IL-2 responsiveness of CD4 and CD8 lymphocytes: further investigations with human IL-2Rbeta transgenic mice

scientific article published on 21 July 2005

Interleukin-2: from T cell growth and homeostasis to immune reconstitution of HIV patients

scientific article published on January 2006

Interleukin-7 (IL-7): immune function, involvement in the pathogenesis of HIV infection and therapeutic potential.

scientific article

Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response

scientific article

Involvement of Bcl-2 and IL-2R in HIV-positive patients whose CD4 cell counts fail to increase rapidly with highly active antiretroviral therapy.

scientific article

Lack of intermediate-affinity interleukin-2 receptor in mice leads to dependence on interleukin-2 receptor alpha, beta and gamma chain expression for T cell growth

scientific article

Lymphoadenopathy in IL-2-deficient mice: further characterization and overexpression of the antiapoptotic molecule cellular FLIP

scientific article published on 01 October 2002

Membrane microdomains and cytoskeleton organization shape and regulate the IL-7 receptor signalosome in human CD4 T-cells.

scientific article published on 17 January 2013

NK cells and polymorphonuclear neutrophils are both critical for IL-2-induced pulmonary vascular leak syndrome.

scientific article published in June 2004

Preserved central memory and activated effector memory CD4+ T-cell subsets in human immunodeficiency virus controllers: an ANRS EP36 study

scientific article published on 10 October 2007

Regulatory dysfunction of the interleukin-2 receptor during HIV infection and the impact of triple combination therapy

scientific article

Regulatory dysfunction of the interleukin-7 receptor in CD4 and CD8 lymphocytes from HIV-infected patients--effects of antiretroviral therapy

scientific article published on 01 July 2006

Role of CD4 lymphocytes in the efficient immune response of HIV controllers

scientific article published in March 2011

Short communication: nuclear JAK3 and its involvement in CD4 activation in HIV-infected patients

scientific article

Soluble IL-7Ralpha (sCD127) and measurement of IL-7 in the plasma of HIV patients

scientific article published in May 2009

Structural analysis and modeling of a synthetic interleukin-2 mimetic and its interleukin-2Rbeta2 receptor

scientific article published on 3 April 2003

Systemic administration of interleukin-2 inhibits inflammatory neutrophil migration: role of nitric oxide

scientific article published on 24 July 2006

T-bet is overexpressed in the CD4+ T cells of HIV Controllers: Retracted

scientific article

The correlation between levels of IL-7Ralpha expression and responsiveness to IL-7 is lost in CD4 lymphocytes from HIV-infected patients

scientific article published on 01 January 2007

The first alpha helix of interleukin (IL)-2 folds as a homotetramer, acts as an agonist of the IL-2 receptor beta chain, and induces lymphokine-activated killer cells

scientific article

Withdrawal: Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response

scientific article published in Journal of Biological Chemistry

[CD4 lymphocytes as targets and actors in the pathogenesis of HIV infection--therapeutic implications].

scientific article published in October 2008

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